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C1orf61 Gene

protein-coding   GIFtS: 39
GCID: GC01M156374

Chromosome 1 Open Reading Frame 61

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
Chromosome 1 Open Reading Frame 611 2     CROC42 3
Contingent Replication Of CDNA-41 2     Protein CROC-42
Transcriptional Activator Of The C Fos Promoter1 2     Transcriptional Activator Of The C-Fos Promoter2
Contingent Replication Of CDNA 42 3     

External Ids:    HGNC: 307801   Entrez Gene: 104852   Ensembl: ENSG000001254627   UniProtKB: Q135363   
ORGUL members:         

Export aliases for C1orf61 gene to outside databases

Previous GC identifers: GC01M153188 GC01M154640 GC01M127734


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for C1orf61 Gene:
C1orf61 (chromosome 1 open reading frame 61) is a protein-coding gene.

UniProtKB/Swiss-Prot: CROC4_HUMAN, Q13536
Function: May play a role in FOS signaling pathways involved in development and remodeling of neurons. Promotes
transcription of the FOS promoter




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000001.10  NT_004487.20  NC_018912.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the C1orf61 gene promoter:
         Max1   Olf-1   Arnt   HNF-4alpha1   MZF-1   S8   c-Rel   ARP-1   c-Myc   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for C1orf61

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat C1orf61


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q22   Ensembl cytogenetic band:  1q22   HGNC cytogenetic band: 1q22

C1orf61 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
C1orf61 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M156374:  view genomic region     (about GC identifiers)

Start:
156,374,042 bp from pter      End:
156,400,493 bp from pter
Size:
26,452 bases      Orientation:
minus strand
ORGUL member locations:
Legend (see complete legend)

ORGUL Member Locations for C1orf61

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: CROC4_HUMAN, Q13536 (See protein sequence)
Recommended Name: Protein CROC-4  
Size: 156 amino acids; 17231 Da
Sequence caution: Sequence=CAI12173.1; Type=Erroneous gene model prediction; Sequence=CAI12175.1; Type=Erroneous
gene model prediction;
Secondary accessions: B1ALL5 B1ALL8

Explore the universe of human proteins at neXtProt for C1orf61: NX_Q13536

Explore proteomics data for C1orf61 at MOPED


See C1orf61 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins: NP_006356.1  
ENSEMBL proteins: 
 ENSP00000383776   ENSP00000357225   ENSP00000310651   ENSP00000357226   ENSP00000350661  

C1orf61 Human Recombinant Protein Products:

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OriGene Protein Over-expression Lysate for C1orf61
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Browse Sino Biological Recombinant Proteins
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Browse Proteins at Cloud-Clone Corp.

 
Search eBioscience for Proteins for C1orf61 

C1orf61 Antibody Products:

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C1orf61 Assay Products:

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Search eBioscience for ELISAs for C1orf61 


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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ProtoNet protein and cluster: Q13536


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Molecular Function:

     UniProtKB/Swiss-Prot Summary: CROC4_HUMAN, Q13536
Function: May play a role in FOS signaling pathways involved in development and remodeling of neurons. Promotes
transcription of the FOS promoter

Phenotypes:
     1 GenomeRNAi human phenotype for C1orf61:

 Increased cell number in G2M,  

Animal Models:
   inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for C1orf61
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   genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for C1orf61
   genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for C1orf61

miRNA
Products:
    
miRTarBase miRNAs that target C1orf61:
hsa-mir-335-5p (MIRT018018)

Block miRNA regulation of human, mouse, rat C1orf61 using miScript Target Protectors
1 qRT-PCR Assays for microRNA that regulate C1orf61:
hsa-miR-924
SwitchGear 3'UTR luciferase reporter plasmidC1orf61 3' UTR sequence
Inhib. RNA
Products:
    
OriGene RNAi products in human, mouse, rat for C1orf61
Predesigned siRNA for gene silencing in human, mouse, rat C1orf61

Gene Editing
Products:
DNA2.0 Custom Protein Engineering Service for C1orf61

Clone
Products:
     
OriGene clones in human, mouse for C1orf61 (see all 7)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: C1orf61 (NM_006365)
Browse Sino Biological Human cDNA Clones
DNA2.0 Custom Codon Optimized Gene Synthesis Service for C1orf61
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C1orf61

Cell Line
Products:
     
GenScript Custom overexpressing Cell Line Services for C1orf61
Browse ESI BIO Cell Lines and PureStem Progenitors for C1orf61 
In Situ Assay
Products:
   

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C1orf61


(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from UniProtKB/Swiss-Prot
CROC4_HUMAN, Q13536: Nucleus. Note=Associates within the nuclear transcriptional apparatus during proliferation
and differentiation
Subcellular locations from COMPARTMENTS: 

CompartmentConfidence
nucleus5
extracellular2
mitochondrion1

Gene Ontology (GO): 1 cellular component term:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005634nucleus IEA--

Find genes that share ontologies with C1orf61           About GenesLikeMe


(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for C1orf61
Interactions:

    Search GeneGlobe Interaction Network for C1orf61

1 Interacting protein for C1orf61 (Q135363) via UniProtKB, MINT, STRING, and/or I2D
InteractantInteraction Details
GeneCardExternal ID(s)
CDK5Q005353I2D: score=2 
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(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Browse Tocris compounds for C1orf61 (CROC4)



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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REFSEQ mRNAs for C1orf61 gene: 
NM_006365.1  

Unigene Cluster for C1orf61:

Chromosome 1 open reading frame 61
Hs.380027  [show with all ESTs]
Unigene Representative Sequence: AK124566
Selected Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 26):
ENST00000608007 ENST00000400991 ENST00000368242 ENST00000471156 ENST00000497824(uc001fov.1 uc001fow.1 uc001fox.1)
ENST00000488498 ENST00000465270 ENST00000462458 ENST00000486517 ENST00000465570
ENST00000310027 ENST00000368243(uc001fou.1) ENST00000498346 ENST00000497822
ENST00000492750 ENST00000357975 ENST00000464238 ENST00000482932
miRNA
Products:
     
Block miRNA regulation of human, mouse, rat C1orf61 using miScript Target Protectors
1 qRT-PCR Assays for microRNA that regulate C1orf61:
hsa-miR-924
SwitchGear 3'UTR luciferase reporter plasmidC1orf61 3' UTR sequence
Inhib. RNA
Products:
     
OriGene RNAi products in human, mouse, rat for C1orf61
Predesigned siRNA for gene silencing in human, mouse, rat C1orf61
Clone
Products:
     
OriGene clones in human, mouse for C1orf61 (see all 7)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: C1orf61 (NM_006365)
DNA2.0 Custom Codon Optimized Gene Synthesis Service for C1orf61
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C1orf61
Primer
Products:
    
OriGene qPCR primer pairs and template standards for C1orf61
OriGene qSTAR qPCR primer pairs in human, mouse for C1orf61
Pre-validated RT2 qPCR Primer Assay in human, mouse / rat C1orf61
  QuantiTect SYBR Green Assays in human, mouse, rat C1orf61
  QuantiFast Probe-based Assays in human, mouse, rat C1orf61

Additional mRNA sequence: 

AK091014.1 AK094493.1 AK095626.1 AK124566.1 AK124870.1 BC010558.1 BC016405.1 BC016978.1 
BC043285.1 BC050448.1 BC050741.1 BC054045.1 BC059943.1 BC065916.1 BC107686.1 BC128199.1 
BC128200.1 BC141918.1 BC141919.1 U49857.1 

24 DOTS entries:

DT.95126609  DT.40107395  DT.95126602  DT.99939234  DT.40284009  DT.95126586  DT.117971  DT.92070426 
DT.95262004  DT.121327860  DT.100678872  DT.101965733  DT.91758170  DT.100791255  DT.91758187  DT.95126588 
DT.121327840  DT.40107394  DT.86838378  DT.91758177  DT.95126585  DT.100665815  DT.92001708  DT.95126599 

Selected AceView cDNA sequences (see all 236):

BC016405 AA012926 BC050448 AA357828 U49857 AI825197 AA442633 BC016978 
H51362 AW589841 Z40002 AL138161 BE551493 CR600735 AL712227 AI205510 
AL535057 BI824013 BC059943 BM707628 AI419151 Z45079 BC054045 CR612522 

GeneLoc Exon Structure

Selected Alternative Splicing Database (ASD) splice patterns (SP) for C1orf61 (see all 22)    About this scheme

ExUns: 1 ^ 2a · 2b ^ 3a · 3b · 3c · 3d · 3e · 3f ^ 4 ^ 5 ^ 6a · 6b ^ 7a · 7b ^ 8 ^ 9a · 9b ^ 10 ^ 11a · 11b ^ 12a · 12b · 12c · 12d · 12e ^
SP1:                                                              -     -     -     -     -     -     -           -                 -     -     -     -     -   
SP2:                                                                                -     -           -     -     -                                   -     -   
SP3:                                                                                            -     -     -     -                 -     -     -     -     -   
SP4:        -           -                                                                                                                                       
SP5:                                                              -     -     -     -     -     -     -     -     -                 -     -     -     -     -   

ExUns: 13 ^ 14a · 14b · 14c ^ 15a · 15b ^ 16a · 16b · 16c · 16d · 16e · 16f · 16g · 16h
SP1:  -                 -                                                               
SP2:  -                                                                                 
SP3:  -                 -                                                               
SP4:                                                                                    
SP5:  -                 -     -     -                                                   


ECgene alternative splicing isoforms for C1orf61

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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C1orf61 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: ACTCCCATAT
C1orf61 Expression
About this image


C1orf61 expression in embryonic tissues and stem cells    About this table
Data from LifeMap, the Embryonic Development and Stem Cells Database
 selected tissues (see all 4) fully expand
 
 Neural Ectoderm (Nervous System)
         Neural ectoderm cells
 
 Neural Tube (Nervous System)
         Floor plate-like cells
 
 Brain (Nervous System)
         Cerebral Cortex
 
 Spinal Cord (Nervous System)
C1orf61 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

C1orf61 Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.380027

UniProtKB/Swiss-Prot: CROC4_HUMAN, Q13536
Tissue specificity: Expressed throughout the brain in the thalamus, subthalamic nucleus, corpus callosum,
hippocampus, substantia nigra, caudate nucleus, and amygdala

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QuantiFast Probe-based Assays in human, mouse, rat C1orf61
In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C1orf61

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of human and chimp.

Orthologs for C1orf61 gene from 1 species (see representative species )    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
chimpanzee
(Pan troglodytes)
Mammalia C1H1orf611 chromosome 1 open reading frame, human C1orf61 89.38(n)
87.91(a)
  457395  XM_513885.4  XP_513885.4 


ENSEMBL Gene Tree for C1orf61 (if available)
TreeFam Gene Tree for C1orf61 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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Selected SNPs for C1orf61 (see all 470)    About this table                                 

Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 1 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs1143949531,2
F--156373560(+) TGAGGG/TTGGAC 1 -- ds50011Minor allele frequency- T:0.06WA 118
rs1123361441,2
F--156373565(+) GTGGAG/CAGAGA 1 -- ds50011Minor allele frequency- C:0.50CSA 2
rs168373681,2
C,F,H--156373583(+) GGAATG/AGAAGA 1 -- ds500117Minor allele frequency- A:0.15NA NS EA WA CSA 1466
rs1468124001,2
--156373810(+) CTGACA/CGGATC 1 -- ds50010--------
rs1406815151,2
C--156373811(+) TGACCA/GGATCA 1 -- ds50010--------
rs1159171101,2
F--156373817(+) GATCAC/TGGATG 1 -- ds50011Minor allele frequency- T:0.01WA 118
rs1145370221,2
C,F--156373880(+) TCACCG/ACCCCA 1 -- ds50011Minor allele frequency- A:0.03WA 118
rs611651861,2
C,F--156373887(+) CCCACC/TCCCTA 1 -- ds50012Minor allele frequency- T:0.08WA 120
rs558709311,2
C,F--156374016(+) TCCAAC/ACCTGT 1 -- ds50011Minor allele frequency- A:0.50WA 2
rs1137662181,2
C--156374047(+) TATTAA/TTGTGA 1 -- ds50010--------

HapMap Linkage Disequilibrium report for C1orf61 (156374042 - 156400493 bp)

Structural Variations
      Database of Genomic Variants (DGV) variations for C1orf61: --
Site Specific Mutation Identification with PCR Assays
SeqTarget long-range PCR primers for resequencing C1orf61
DNA2.0 Custom Variant and Variant Library Synthesis for C1orf61

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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PubMed articles for C1orf61 gene integrated from 10 sources:
(articles sorted by number of sources associating them with C1orf61)
    Utopia: connect your pdf to the dynamic
world of online information

  1. CROC-4: a novel brain specific transcriptional activator of c-fos expressed from proliferation through to maturation of multiple neuronal cell types. (PubMed id 10995546)1, 2, 3 Jeffrey P.L.... Lin S.L. (Mol. Cell. Neurosci. 2000)
  2. C1orf61 acts as a tumor activator in human hepatocellular carcinoma and is associated with tumorigenesis and metastasis. (PubMed id 23012322)1, 3 Hu H.M....Li W. (FASEB J. 2013)
  3. Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women. (PubMed id 22589738)1 Fox C.S....Borecki I.B. (PLoS Genet. 2012)
  4. Eight genes are highly associated with BMD variation in postmenopausal Caucasian women. (PubMed id 19922823)1 Reppe S....Gautvik K.M. (Bone 2010)
  5. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)2 Gregory S.G.... Bentley D.R. (Nature 2006)
  6. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (Nat. Genet. 2004)
  7. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

(in PubMed, OMIM, and NCBI Bookshelf)
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 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 10485 HGNC: 30780 AceView: CROC4 Ensembl:ENSG00000125462 euGenes: HUgn10485
ECgene: C1orf61 H-InvDB: C1orf61

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for C1orf61 Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for C1orf61 gene:
Search GeneIP for patents involving C1orf61

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014

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