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Aliases for C1orf52 Gene

Aliases for C1orf52 Gene

  • Chromosome 1 Open Reading Frame 52 2 3
  • BCL10-Associated Gene Protein 3 4
  • UPF0690 Protein C1orf52 3
  • Gm117 3
  • BAG 4

External Ids for C1orf52 Gene

Previous GeneCards Identifiers for C1orf52 Gene

  • GC01M085428
  • GC01M085715
  • GC01M083826

Summaries for C1orf52 Gene

GeneCards Summary for C1orf52 Gene

C1orf52 (Chromosome 1 Open Reading Frame 52) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C1orf52 Gene

Genomics for C1orf52 Gene

Regulatory Elements for C1orf52 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for C1orf52 Gene

85,249,953 bp from pter
85,259,672 bp from pter
9,720 bases
Minus strand

Genomic View for C1orf52 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for C1orf52 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C1orf52 Gene

Proteins for C1orf52 Gene

  • Protein details for C1orf52 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    UPF0690 protein C1orf52
    Protein Accession:
    Secondary Accessions:
    • B3KX89
    • Q8TDK5
    • Q8TDK6

    Protein attributes for C1orf52 Gene

    182 amino acids
    Molecular mass:
    20599 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for C1orf52 Gene


neXtProt entry for C1orf52 Gene

Proteomics data for C1orf52 Gene at MOPED

Post-translational modifications for C1orf52 Gene

  • Ubiquitination at Lys78
  • Modification sites at PhosphoSitePlus

Other Protein References for C1orf52 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C1orf52 Gene

Domains for C1orf52 Gene

Protein Domains for C1orf52 Gene


Suggested Antigen Peptide Sequences for C1orf52 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the UPF0690 family.
  • Belongs to the UPF0690 family.
genes like me logo Genes that share domains with C1orf52: view

No data available for Gene Families for C1orf52 Gene

Function for C1orf52 Gene

Gene Ontology (GO) - Molecular Function for C1orf52 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0044822 poly(A) RNA binding IDA 22658674
genes like me logo Genes that share ontologies with C1orf52: view

Animal Model Products

CRISPR Products

miRNA for C1orf52 Gene

miRTarBase miRNAs that target C1orf52

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C1orf52

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targets and HOMER Transcription for C1orf52 Gene

Localization for C1orf52 Gene

Subcellular locations from

Jensen Localization Image for C1orf52 Gene COMPARTMENTS Subcellular localization image for C1orf52 gene
Compartment Confidence
nucleus 3
cytosol 2

Gene Ontology (GO) - Cellular Components for C1orf52 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IDA --
GO:0005654 nucleoplasm IDA --
genes like me logo Genes that share ontologies with C1orf52: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for C1orf52 Gene

Pathways for C1orf52 Gene

SuperPathways for C1orf52 Gene

No Data Available

Interacting Proteins for C1orf52 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
Selected Interacting proteins: Q8N6N3-CA052_HUMAN ENSP00000419417 for C1orf52 Gene via MINT STRING I2D

Gene Ontology (GO) - Biological Process for C1orf52 Gene


No data available for Pathways by source for C1orf52 Gene

Transcripts for C1orf52 Gene

Unigene Clusters for C1orf52 Gene

Chromosome 1 open reading frame 52:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C1orf52

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C1orf52 Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4a · 4b
SP2: -

Relevant External Links for C1orf52 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C1orf52 Gene

mRNA expression in normal human tissues for C1orf52 Gene

Protein differential expression in normal tissues for C1orf52 Gene

This gene is overexpressed in Cervix (44.9) and Lung (19.4).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for C1orf52 Gene

SOURCE GeneReport for Unigene cluster for C1orf52 Gene Hs.26226

mRNA Expression by UniProt/SwissProt for C1orf52 Gene

Tissue specificity: Expressed in all tissues tested including heart, placenta, liver, skeletal muscle, kidney and pancreas. Weak expression in brain and lung.
genes like me logo Genes that share expressions with C1orf52: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and Expression partners for C1orf52 Gene

Orthologs for C1orf52 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C1orf52 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia C3H1orf52 35
  • 90.29 (n)
  • 92.86 (a)
C1orf52 36
  • 93 (a)
(Canis familiaris)
Mammalia C6H1orf52 35
  • 89.74 (n)
  • 93.96 (a)
C1orf52 36
  • 94 (a)
(Mus musculus)
Mammalia 2410004B18Rik 35
  • 82.04 (n)
  • 86.11 (a)
2410004B18Rik 16
2410004B18Rik 36
  • 84 (a)
(Pan troglodytes)
Mammalia C1H1orf52 35
  • 99.82 (n)
  • 100 (a)
C1orf52 36
  • 100 (a)
(Rattus norvegicus)
Mammalia RGD1560065 35
  • 82.92 (n)
  • 83.95 (a)
(Monodelphis domestica)
Mammalia C1orf52 36
  • 76 (a)
(Gallus gallus)
Aves C8H1ORF52 35
  • 67.05 (n)
  • 65.34 (a)
C8H1ORF52 36
  • 53 (a)
(Anolis carolinensis)
Reptilia C1orf52 36
  • 57 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia c1orf52 35
  • 71.01 (n)
  • 70.19 (a)
(Danio rerio)
Actinopterygii zgc65873 35
zgc:65873 35
  • 58.05 (n)
  • 56.18 (a)
CZv9_NA991H1orf52 36
  • 44 (a)
Species with no ortholog for C1orf52:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C1orf52 Gene

Gene Tree for C1orf52 (if available)
Gene Tree for C1orf52 (if available)

Paralogs for C1orf52 Gene

No data available for Paralogs for C1orf52 Gene

Variants for C1orf52 Gene

Sequence variations from dbSNP and Humsavar for C1orf52 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs11370 -- 85,250,195(+) TGACA(C/T)GTGGG utr-variant-3-prime, nc-transcript-variant
rs750517 -- 85,254,330(-) TTTGT(A/G)TGAAC intron-variant
rs1077996 -- 85,254,405(-) CAAAA(A/G)AAAAA intron-variant
rs3179654 -- 85,250,026(-) CCTCT(C/T)GCCTT utr-variant-3-prime, nc-transcript-variant
rs4074156 -- 85,253,927(+) AATTG(C/T)AGCTT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C1orf52 Gene

Variant ID Type Subtype PubMed ID
esv34165 CNV Loss 18971310
nsv830459 CNV Loss 17160897

Relevant External Links for C1orf52 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C1orf52 Gene

Disorders for C1orf52 Gene

Relevant External Links for C1orf52

Human Genome Epidemiology (HuGE) Navigator

No disorders were found for C1orf52 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for C1orf52 Gene

Publications for C1orf52 Gene

  1. Identification of six novel genes by experimental validation of GeneMachine predicted genes. (PMID: 11891061) Makalowska I. … Carpten J.D. (Gene 2002) 2 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. Immunoaffinity profiling of tyrosine phosphorylation in cancer cells. (PMID: 15592455) Rush J. … Comb M.J. (Nat. Biotechnol. 2005) 3 4
  4. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4
  5. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PMID: 17081983) Olsen J.V. … Mann M. (Cell 2006) 3 4

Products for C1orf52 Gene

Sources for C1orf52 Gene

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