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Aliases for C1orf50 Gene

Aliases for C1orf50 Gene

  • Chromosome 1 Open Reading Frame 50 2 3

External Ids for C1orf50 Gene

Previous GeneCards Identifiers for C1orf50 Gene

  • GC01P042903
  • GC01P043005
  • GC01P043232
  • GC01P041352

Summaries for C1orf50 Gene

GeneCards Summary for C1orf50 Gene

C1orf50 (Chromosome 1 Open Reading Frame 50) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C1orf50 Gene

Genomics for C1orf50 Gene

Regulatory Elements for C1orf50 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for C1orf50 Gene

Chromosome:
1
Start:
42,767,245 bp from pter
End:
42,794,493 bp from pter
Size:
27,249 bases
Orientation:
Plus strand

Genomic View for C1orf50 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for C1orf50 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C1orf50 Gene

Proteins for C1orf50 Gene

  • Protein details for C1orf50 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9BV19-CA050_HUMAN
    Recommended name:
    Uncharacterized protein C1orf50
    Protein Accession:
    Q9BV19

    Protein attributes for C1orf50 Gene

    Size:
    199 amino acids
    Molecular mass:
    21877 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C1orf50 Gene

Proteomics data for C1orf50 Gene at MOPED

Post-translational modifications for C1orf50 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C1orf50 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C1orf50 Gene

Domains & Families for C1orf50 Gene

Protein Domains for C1orf50 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for C1orf50 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C1orf50: view

No data available for Gene Families and UniProtKB/Swiss-Prot for C1orf50 Gene

Function for C1orf50 Gene

Gene Ontology (GO) - Molecular Function for C1orf50 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with C1orf50: view
genes like me logo Genes that share phenotypes with C1orf50: view

Animal Model Products

CRISPR Products

miRNA for C1orf50 Gene

miRTarBase miRNAs that target C1orf50

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C1orf50

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targets and HOMER Transcription for C1orf50 Gene

Localization for C1orf50 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for C1orf50 Gene COMPARTMENTS Subcellular localization image for C1orf50 gene
Compartment Confidence
nucleus 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C1orf50 Gene

Pathways & Interactions for C1orf50 Gene

SuperPathways for C1orf50 Gene

No Data Available

Gene Ontology (GO) - Biological Process for C1orf50 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C1orf50 Gene

Drugs & Compounds for C1orf50 Gene

No Compound Related Data Available

Transcripts for C1orf50 Gene

mRNA/cDNA for C1orf50 Gene

Unigene Clusters for C1orf50 Gene

Chromosome 1 open reading frame 50:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C1orf50

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C1orf50 Gene

ExUns: 1a · 1b · 1c · 1d · 1e ^ 2 ^ 3a · 3b ^ 4a · 4b ^ 5a · 5b · 5c · 5d
SP1: -
SP2: - -
SP3: - - -
SP4:
SP5: -
SP6: - - -

Relevant External Links for C1orf50 Gene

GeneLoc Exon Structure for
C1orf50
ECgene alternative splicing isoforms for
C1orf50

Expression for C1orf50 Gene

mRNA expression in normal human tissues for C1orf50 Gene

Protein differential expression in normal tissues from HIPED for C1orf50 Gene

This gene is overexpressed in Fetal ovary (17.1) and Peripheral blood mononuclear cells (9.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for C1orf50 Gene



SOURCE GeneReport for Unigene cluster for C1orf50 Gene Hs.148845

genes like me logo Genes that share expression patterns with C1orf50: view

Protein tissue co-expression partners for C1orf50 Gene

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for C1orf50 Gene

Orthologs for C1orf50 Gene

This gene was present in the common ancestor of animals.

Orthologs for C1orf50 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia C3H1orf50 35
  • 87.8 (n)
  • 86.6 (a)
C3H1ORF50 36
  • 84 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C15H1orf50 35
  • 91.57 (n)
  • 89.41 (a)
C1orf50 36
  • 74 (a)
OneToOne
mouse
(Mus musculus)
Mammalia AU022252 35
  • 85.09 (n)
  • 84.42 (a)
AU022252 16
AU022252 36
  • 84 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia C1H1orf50 35
  • 99.66 (n)
  • 99.5 (a)
C1H1ORF50 36
  • 99 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia RGD1564804 35
  • 84.25 (n)
  • 81.91 (a)
oppossum
(Monodelphis domestica)
Mammalia C1orf50 36
  • 73 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia C1orf50 36
  • 71 (a)
OneToOne
chicken
(Gallus gallus)
Aves C1ORF50 35
  • 76.52 (n)
  • 81.06 (a)
C1orf50 36
  • 68 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia c1orf50 35
  • 68.41 (n)
  • 72.67 (a)
Str.11019 35
zebrafish
(Danio rerio)
Actinopterygii zgc:112255 35
  • 68.8 (n)
  • 71.51 (a)
C11H1orf50 36
  • 66 (a)
OneToOne
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.4067 35
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP008853 35
  • 56.29 (n)
  • 49.67 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG31800 35
  • 54.9 (n)
  • 48.74 (a)
CG31800 36
  • 36 (a)
OneToOne
worm
(Caenorhabditis elegans)
Secernentea C08B11.9 35
  • 51.52 (n)
  • 41.26 (a)
C08B11.9 36
  • 35 (a)
OneToOne
Species with no ortholog for C1orf50:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for C1orf50 Gene

ENSEMBL:
Gene Tree for C1orf50 (if available)
TreeFam:
Gene Tree for C1orf50 (if available)

Paralogs for C1orf50 Gene

(1) SIMAP similar genes for C1orf50 Gene using alignment to 8 proteins:

genes like me logo Genes that share paralogs with C1orf50: view

No data available for Paralogs for C1orf50 Gene

Variants for C1orf50 Gene

Sequence variations from dbSNP and Humsavar for C1orf50 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs1801587 -- 42,775,249(+) TGCCT(A/G)CAAAC reference, missense, nc-transcript-variant
rs2760074 -- 42,771,951(+) gcctc(A/C/T)gtgac intron-variant
rs2760075 -- 42,773,724(+) TAATC(A/G)TTGTG intron-variant
rs4660232 -- 42,769,359(+) tgggc(A/G)acatg intron-variant
rs4660666 -- 42,769,351(+) gacca(A/G)cctgg intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C1orf50 Gene

Variant ID Type Subtype PubMed ID
nsv829682 CNV Loss 17160897

Variation tolerance for C1orf50 Gene

Residual Variation Intolerance Score: 65.14% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C1orf50 Gene

HapMap Linkage Disequilibrium report
C1orf50

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C1orf50 Gene

Disorders for C1orf50 Gene

Relevant External Links for C1orf50

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C1orf50
genes like me logo Genes that share disorders with C1orf50: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C1orf50 Gene

Publications for C1orf50 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 67
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 67
  3. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 67
  4. N-terminal acetylome analyses and functional insights of the N- terminal acetyltransferase NatB. (PMID: 22814378) Van Damme P. … Aldabe R. (Proc. Natl. Acad. Sci. U.S.A. 2012) 67
  5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 67

Products for C1orf50 Gene

Sources for C1orf50 Gene

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