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Aliases for C1orf43 Gene

Aliases for C1orf43 Gene

  • Chromosome 1 Open Reading Frame 43 2 3
  • Hepatitis C Virus NS5A-Transactivated Protein 4 3 4
  • HCV NS5A-Transactivated Protein 4 3 4
  • NS5ATP4 3 4
  • S863-3 3 4
  • Uncharacterized Protein C1orf43 3
  • Protein NICE-3 4
  • HSPC012 3
  • NICE-3 3
  • NICE3 4

External Ids for C1orf43 Gene

Summaries for C1orf43 Gene

GeneCards Summary for C1orf43 Gene

C1orf43 (Chromosome 1 Open Reading Frame 43) is a Protein Coding gene. Diseases associated with C1orf43 include hepatitis c virus and hepatitis c. GO annotations related to this gene include coenzyme binding and oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C1orf43 Gene

Genomics for C1orf43 Gene

Genomic Location for C1orf43 Gene

Start:
154,206,706 bp from pter
End:
154,220,797 bp from pter
Size:
14,092 bases
Orientation:
Minus strand

Genomic View for C1orf43 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for C1orf43 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C1orf43 Gene

Regulatory Elements for C1orf43 Gene

Proteins for C1orf43 Gene

  • Protein details for C1orf43 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9BWL3-CA043_HUMAN
    Recommended name:
    Uncharacterized protein C1orf43
    Protein Accession:
    Q9BWL3
    Secondary Accessions:
    • A8K3G8
    • D3DV72
    • D3DV74
    • Q5M801
    • Q5VU73
    • Q5VU83
    • Q96HP7
    • Q9UFU2
    • Q9UGL7
    • Q9UGL8
    • Q9Y2R6

    Protein attributes for C1orf43 Gene

    Size:
    253 amino acids
    Molecular mass:
    28779 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=CAH71276.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

    Alternative splice isoforms for C1orf43 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for C1orf43 Gene

Proteomics data for C1orf43 Gene at MOPED

Post-translational modifications for C1orf43 Gene

  • Modification sites at PhosphoSitePlus
  • Ubiquitination at Lys73, Lys151, and Lys191

No data available for DME Specific Peptides for C1orf43 Gene

Domains for C1orf43 Gene

Protein Domains for C1orf43 Gene

InterPro:
ProtoNet:
genes like me logo Genes that share domains with C1orf43: view

No data available for Gene Families and UniProtKB/Swiss-Prot for C1orf43 Gene

Function for C1orf43 Gene

Gene Ontology (GO) - Molecular Function for C1orf43 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IEA --
GO:0050662 coenzyme binding IEA --
genes like me logo Genes that share ontologies with C1orf43: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for C1orf43 Gene

Localization for C1orf43 Gene

Subcellular locations from UniProtKB/Swiss-Prot for C1orf43 Gene

Membrane; Single-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for C1orf43 Gene COMPARTMENTS Subcellular localization image for C1orf43 gene
Compartment Confidence
extracellular 2
plasma membrane 2
cytosol 1
endoplasmic reticulum 1
golgi apparatus 1
mitochondrion 1

Gene Ontology (GO) - Cellular Components for C1orf43 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with C1orf43: view

Pathways for C1orf43 Gene

SuperPathways for C1orf43 Gene

No Data Available

Interacting Proteins for C1orf43 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000357507%0d%0a9606.ENSP00000344818%0d%0a
Selected Interacting proteins: ENSP00000357507 for C1orf43 Gene via STRING

Symbol External ID(s) Details
UBC

Gene Ontology (GO) - Biological Process for C1orf43 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0055114 oxidation-reduction process IEA --
genes like me logo Genes that share ontologies with C1orf43: view

No data available for Pathways by source for C1orf43 Gene

Transcripts for C1orf43 Gene

Unigene Clusters for C1orf43 Gene

Chromosome 1 open reading frame 43:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for C1orf43 Gene

ExUns: 1a · 1b · 1c · 1d · 1e · 1f · 1g · 1h · 1i ^ 2 ^ 3 ^ 4 ^ 5a · 5b · 5c · 5d ^ 6a · 6b · 6c · 6d · 6e ^ 7a · 7b · 7c · 7d · 7e ·
SP1: - - - - -
SP2: - - - - - -
SP3: - - - - - -
SP4: - - - - - - -
SP5: - -
SP6: - - - - - -
SP7: - - - - - - -
SP8: - - -
SP9: - - - - - - -
SP10: - - - - - - - -
SP11: - - -
SP12: - - - - - - -
SP13: - - - - - - - -
SP14: - - -
SP15:

ExUns: 7f · 7g · 7h · 7i
SP1:
SP2:
SP3:
SP4:
SP5:
SP6:
SP7:
SP8:
SP9:
SP10:
SP11:
SP12:
SP13:
SP14:
SP15:

Relevant External Links for C1orf43 Gene

GeneLoc Exon Structure for
C1orf43
ECgene alternative splicing isoforms for
C1orf43

Expression for C1orf43 Gene

mRNA expression in normal human tissues for C1orf43 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for C1orf43 Gene

SOURCE GeneReport for Unigene cluster for C1orf43 Gene Hs.287471

genes like me logo Genes that share expressions with C1orf43: view

Orthologs for C1orf43 Gene

This gene was present in the common ancestor of animals.

Orthologs for C1orf43 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C1H1orf43 36
  • 99.6 (n)
  • 99.21 (a)
C1orf43 37
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia -- 37
  • 87 (a)
OneToMany
-- 37
  • 96 (a)
OneToMany
C3H1orf43 36
  • 93.28 (n)
  • 95.65 (a)
dog
(Canis familiaris)
Mammalia C1orf43 37
  • 96 (a)
OneToOne
C7H1orf43 36
  • 91.96 (n)
  • 96.05 (a)
mouse
(Mus musculus)
Mammalia 4933434E20Rik 36
  • 89.72 (n)
  • 95.65 (a)
4933434E20Rik 16
4933434E20Rik 37
  • 96 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia C1orf43 37
  • 93 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia C1orf43 37
  • 84 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia LOC361985 36
  • 88.79 (n)
  • 95.32 (a)
chicken
(Gallus gallus)
Aves C1orf43 37
  • 83 (a)
OneToOne
C25H1ORF43 36
  • 72.99 (n)
  • 85.31 (a)
lizard
(Anolis carolinensis)
Reptilia C1orf43 37
  • 63 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia Xl.16623 36
tropical clawed frog
(Silurana tropicalis)
Amphibia c1orf43 36
  • 69.83 (n)
  • 73.52 (a)
zebrafish
(Danio rerio)
Actinopterygii C16H1orf43 (1 of 2) 37
  • 63 (a)
OneToMany
C16H1orf43 (2 of 2) 37
  • 75 (a)
OneToMany
zgc:123238 36
  • 63.65 (n)
  • 66.26 (a)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP004471 36
  • 50.77 (n)
  • 42.53 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG6665 36
  • 47.62 (n)
  • 41.94 (a)
CG6665 37
  • 26 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea -- 37
  • 25 (a)
OneToOne
Species with no ortholog for C1orf43:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C1orf43 Gene

ENSEMBL:
Gene Tree for C1orf43 (if available)
TreeFam:
Gene Tree for C1orf43 (if available)

Paralogs for C1orf43 Gene

Selected SIMAP similar genes for C1orf43 Gene using alignment to 1 proteins:

Pseudogenes.org Pseudogenes for C1orf43 Gene

genes like me logo Genes that share paralogs with C1orf43: view

No data available for Paralogs for C1orf43 Gene

Variants for C1orf43 Gene

Sequence variations from dbSNP and Humsavar for C1orf43 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs4378197 -- 154,211,546(+) TGGCT(A/C)GGATG intron-variant, utr-variant-3-prime
rs4390167 -- 154,209,889(+) ctggc(C/T)TAAtt intron-variant
rs4504882 -- 154,209,750(+) cccgg(A/C)taatt intron-variant
rs4845609 -- 154,209,478(+) tagag(G/T)gcagt intron-variant
rs7551128 -- 154,209,936(+) gccca(G/T)gttgg intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C1orf43 Gene

Variant ID Type Subtype PubMed ID
nsv2954 CNV Insertion 18451855

Relevant External Links for C1orf43 Gene

HapMap Linkage Disequilibrium report
C1orf43

Disorders for C1orf43 Gene

genes like me logo Genes that share disorders with C1orf43: view

No data available for UniProtKB/Swiss-Prot for C1orf43 Gene

Publications for C1orf43 Gene

  1. Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PMID: 11042152) Zhang Q.-H. … Chen Z. (Genome Res. 2000) 2 3 4
  2. Identification of human epidermal differentiation complex (EDC)- encoded genes by subtractive hybridization of entire YACs to a gridded keratinocyte cDNA library. (PMID: 11230159) Marenholz I. … Mischke D. (Genome Res. 2001) 2 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4
  5. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P. … Vidal M. (Genomics 2007) 3

Products for C1orf43 Gene

  • antibodies-online peptides for C1orf43
  • antibodies-online antibodies for C1orf43
  • antibodies-online kits for C1orf43

Sources for C1orf43 Gene

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