Free for academic non-profit institutions. Other users need a Commercial license

Aliases for C1orf27 Gene

Aliases for C1orf27 Gene

  • Chromosome 1 Open Reading Frame 27 2 3
  • Transactivated By Recombinant Transforming Growth Factor Beta 2 3
  • Transactivated By Transforming Growth Factor Beta Protein 1 3 4
  • LAG1-Interacting Protein 3 4
  • TTG1 3 4
  • ODR4 3 4
  • Odorant Response Abnormal 4 3
  • Protein Odr-4 Homolog 3
  • HODR-4 4
  • Odr-4 3
  • TTG1A 4

External Ids for C1orf27 Gene

Summaries for C1orf27 Gene

GeneCards Summary for C1orf27 Gene

C1orf27 (Chromosome 1 Open Reading Frame 27) is a Protein Coding gene. GO annotations related to this gene include oxidoreductase activity.

UniProtKB/Swiss-Prot for C1orf27 Gene

  • May play a role in the trafficking of a subset of G-protein coupled receptors.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C1orf27 Gene

Genomics for C1orf27 Gene

Genomic Location for C1orf27 Gene

186,375,758 bp from pter
186,421,378 bp from pter
45,621 bases
Plus strand

Genomic View for C1orf27 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for C1orf27 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C1orf27 Gene

Regulatory Elements for C1orf27 Gene

Proteins for C1orf27 Gene

  • Protein details for C1orf27 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein odr-4 homolog
    Protein Accession:
    Secondary Accessions:
    • B4DNY0
    • E9PFR7
    • Q19CC6
    • Q8WYB6
    • Q9BTS2
    • Q9H6A6
    • Q9NX06

    Protein attributes for C1orf27 Gene

    454 amino acids
    Molecular mass:
    51103 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAB15356.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for C1orf27 Gene


neXtProt entry for C1orf27 Gene

Proteomics data for C1orf27 Gene at MOPED

Post-translational modifications for C1orf27 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C1orf27 Gene

No data available for DME Specific Peptides for C1orf27 Gene

Domains for C1orf27 Gene

Protein Domains for C1orf27 Gene


Graphical View of Domain Structure for InterPro Entry



  • Belongs to the ODR-4 family.:
    • Q5SWX8
genes like me logo Genes that share domains with C1orf27: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for C1orf27 Gene

Function for C1orf27 Gene

Molecular function for C1orf27 Gene

UniProtKB/Swiss-Prot Function: May play a role in the trafficking of a subset of G-protein coupled receptors.

Gene Ontology (GO) - Molecular Function for C1orf27 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008270 zinc ion binding IEA --
GO:0016491 oxidoreductase activity IEA --
genes like me logo Genes that share ontologies with C1orf27: view

Phenotypes for C1orf27 Gene

genes like me logo Genes that share phenotypes with C1orf27: view

miRNA for C1orf27 Gene

miRTarBase miRNAs that target C1orf27

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for C1orf27 Gene

Localization for C1orf27 Gene

Subcellular locations from UniProtKB/Swiss-Prot for C1orf27 Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for C1orf27 Gene COMPARTMENTS Subcellular localization image for C1orf27 gene
Compartment Confidence
plasma membrane 3
cytosol 1
nucleus 1
peroxisome 1

Gene Ontology (GO) - Cellular Components for C1orf27 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with C1orf27: view

Pathways for C1orf27 Gene

SuperPathways for C1orf27 Gene

No Data Available

Interacting Proteins for C1orf27 Gene

STRING Interaction Network Preview (showing 4 interactants - click image to see details)
Selected Interacting proteins: ENSP00000287859 for C1orf27 Gene via STRING

Gene Ontology (GO) - Biological Process for C1orf27 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0055114 oxidation-reduction process IEA --
genes like me logo Genes that share ontologies with C1orf27: view

No data available for Pathways by source for C1orf27 Gene

Transcripts for C1orf27 Gene

Unigene Clusters for C1orf27 Gene

Chromosome 1 open reading frame 27:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for C1orf27 Gene

No ASD Table

Relevant External Links for C1orf27 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C1orf27 Gene

mRNA expression in normal human tissues for C1orf27 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for C1orf27 Gene

SOURCE GeneReport for Unigene cluster for C1orf27 Gene Hs.371210

mRNA Expression by UniProt/SwissProt for C1orf27 Gene

Tissue specificity: Ubiquitously expressed.
genes like me logo Genes that share expressions with C1orf27: view

No data available for mRNA differential expression in normal tissues for C1orf27 Gene

Orthologs for C1orf27 Gene

This gene was present in the common ancestor of animals.

Orthologs for C1orf27 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia C1H1orf27 35
  • 99.85 (n)
  • 99.56 (a)
C1orf27 36
  • 100 (a)
(Bos Taurus)
Mammalia C16H1orf27 35
  • 90.82 (n)
  • 88.99 (a)
C1orf27 36
  • 89 (a)
(Canis familiaris)
Mammalia C1orf27 36
  • 88 (a)
C7H1orf27 35
  • 90.68 (n)
  • 88.55 (a)
(Mus musculus)
Mammalia BC003331 35
  • 87.84 (n)
  • 86.8 (a)
BC003331 16
BC003331 36
  • 87 (a)
(Monodelphis domestica)
Mammalia C1orf27 36
  • 74 (a)
(Ornithorhynchus anatinus)
Mammalia C1orf27 36
  • 70 (a)
(Rattus norvegicus)
Mammalia RGD1307830 35
  • 87.4 (n)
  • 85.68 (a)
(Gallus gallus)
Aves C8H1ORF27 35
  • 69.88 (n)
  • 64.13 (a)
C8H1ORF27 36
  • 64 (a)
(Anolis carolinensis)
Reptilia C1orf27 36
  • 62 (a)
African clawed frog
(Xenopus laevis)
Amphibia Xl.10013 35
tropical clawed frog
(Silurana tropicalis)
Amphibia c1orf27 35
  • 59.55 (n)
  • 50.11 (a)
Str.15466 35
(Danio rerio)
Actinopterygii C2H1orf27 36
  • 45 (a)
zgc:63674 35
  • 53.71 (n)
  • 46.52 (a)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP006119 35
  • 41.76 (n)
  • 31.18 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG10616 35
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 22 (a)
Species with no ortholog for C1orf27:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C1orf27 Gene

Gene Tree for C1orf27 (if available)
Gene Tree for C1orf27 (if available)

Paralogs for C1orf27 Gene

No data available for Paralogs for C1orf27 Gene

Variants for C1orf27 Gene

Sequence variations from dbSNP and Humsavar for C1orf27 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs8824 -- 186,421,171(+) CACAA(A/C)TTCAG utr-variant-3-prime
rs958713 -- 186,382,463(-) TGTTT(C/T)TTGTT intron-variant
rs1003127 -- 186,389,456(-) AGATA(C/T)GCGTA intron-variant
rs1285177 -- 186,388,108(+) AATTA(A/C)ATTTT intron-variant
rs1285178 -- 186,388,162(+) AAAAA(G/T)GTTAG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C1orf27 Gene

Variant ID Type Subtype PubMed ID
nsv872589 CNV Loss 21882294

Relevant External Links for C1orf27 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C1orf27 Gene

Disorders for C1orf27 Gene

No disorders were found for C1orf27 Gene.

No data available for UniProtKB/Swiss-Prot for C1orf27 Gene

Publications for C1orf27 Gene

  1. Protein expression, genomic structure, and polymorphisms of oculomedin. (PMID: 12868032) Fujiwara N. … Ohtsuki H. (Ophthalmic Genet. 2003) 2 3
  2. Ubiquitously expressed GPCR membrane-trafficking orthologs. (PMID: 15718105) Lehman C.W. … Komives C.F. (Genomics 2005) 3 4
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  4. V(D)J recombinase binding and cleavage of cryptic recombination signal sequences identified from lymphoid malignancies. (PMID: 18187418) Zhang M. … Swanson P.C. (J. Biol. Chem. 2008) 3
  5. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PMID: 21139048) Danielsen J.M. … Nielsen M.L. (Mol. Cell Proteomics 2011) 3

Products for C1orf27 Gene

Sources for C1orf27 Gene

Back to Top