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Aliases for C1orf228 Gene

Aliases for C1orf228 Gene

  • Chromosome 1 Open Reading Frame 228 2 3 5
  • NCRNA00082 3 4
  • P40 3 4
  • Non-Protein Coding RNA 82 2

External Ids for C1orf228 Gene

Previous HGNC Symbols for C1orf228 Gene

  • NCRNA00082

Previous GeneCards Identifiers for C1orf228 Gene

  • GC01P044938
  • GC01P045140
  • GC01P043255

Summaries for C1orf228 Gene

GeneCards Summary for C1orf228 Gene

C1orf228 (Chromosome 1 Open Reading Frame 228) is a Protein Coding gene. GO annotations related to this gene include binding.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C1orf228 Gene

Genomics for C1orf228 Gene

Regulatory Elements for C1orf228 Gene

Enhancers for C1orf228 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around C1orf228 on UCSC Golden Path with GeneCards custom track

Genomic Location for C1orf228 Gene

Chromosome:
1
Start:
44,674,692 bp from pter
End:
44,725,591 bp from pter
Size:
50,900 bases
Orientation:
Plus strand

Genomic View for C1orf228 Gene

Genes around C1orf228 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C1orf228 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C1orf228 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C1orf228 Gene

Proteins for C1orf228 Gene

  • Protein details for C1orf228 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6PIY5-CA228_HUMAN
    Recommended name:
    Uncharacterized protein C1orf228
    Protein Accession:
    Q6PIY5
    Secondary Accessions:
    • A1KXE5

    Protein attributes for C1orf228 Gene

    Size:
    440 amino acids
    Molecular mass:
    48855 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for C1orf228 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for C1orf228 Gene

Proteomics data for C1orf228 Gene at MOPED

Post-translational modifications for C1orf228 Gene

No Post-translational modifications

No data available for DME Specific Peptides for C1orf228 Gene

Domains & Families for C1orf228 Gene

Protein Domains for C1orf228 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for C1orf228 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C1orf228: view

No data available for Gene Families and UniProtKB/Swiss-Prot for C1orf228 Gene

Function for C1orf228 Gene

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for C1orf228 Gene

Localization for C1orf228 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for C1orf228 Gene COMPARTMENTS Subcellular localization image for C1orf228 gene
Compartment Confidence
cytosol 3
nucleus 2
endoplasmic reticulum 1
mitochondrion 1
peroxisome 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C1orf228 Gene

Pathways & Interactions for C1orf228 Gene

SuperPathways for C1orf228 Gene

No Data Available

Interacting Proteins for C1orf228 Gene

Gene Ontology (GO) - Biological Process for C1orf228 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C1orf228 Gene

Drugs & Compounds for C1orf228 Gene

No Compound Related Data Available

Transcripts for C1orf228 Gene

Unigene Clusters for C1orf228 Gene

Chromosome 1 open reading frame 228:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for C1orf228 Gene

ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3 ^ 4 ^ 5a · 5b · 5c ^ 6a · 6b ^ 7 ^ 8 ^ 9 ^ 10a · 10b ^ 11a · 11b · 11c ^ 12a · 12b · 12c ^ 13 ^ 14a · 14b
SP1: - - - -
SP2: - -
SP3: - -
SP4: -
SP5: - - - - - -
SP6: - -
SP7: - - - - - - - - -
SP8: - - - - - - - -
SP9: -
SP10:

Relevant External Links for C1orf228 Gene

GeneLoc Exon Structure for
C1orf228
ECgene alternative splicing isoforms for
C1orf228

Expression for C1orf228 Gene

mRNA expression in normal human tissues for C1orf228 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for C1orf228 Gene

This gene is overexpressed in Whole Blood (x6.9) and Testis (x4.8).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C1orf228 Gene



SOURCE GeneReport for Unigene cluster for C1orf228 Gene Hs.173679

genes like me logo Genes that share expression patterns with C1orf228: view

Primer Products

No data available for Protein differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for C1orf228 Gene

Orthologs for C1orf228 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C1orf228 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia C3H1orf228 35
  • 86.74 (n)
  • 83.64 (a)
C1orf228 36
  • 82 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C15H1orf228 35
  • 86.36 (n)
  • 82.05 (a)
C1orf228 36
  • 81 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Gm1661 35
  • 81.79 (n)
  • 78.47 (a)
Gm1661 16
Gm1661 36
  • 76 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia C1H1orf228 35
  • 99.39 (n)
  • 99.77 (a)
C1orf228 36
  • 98 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia RGD1563714 35
  • 81.89 (n)
  • 77.73 (a)
oppossum
(Monodelphis domestica)
Mammalia C1orf228 36
  • 61 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia C1orf228 36
  • 60 (a)
OneToOne
chicken
(Gallus gallus)
Aves C8H1orf228 35
  • 64.58 (n)
  • 59.65 (a)
C1orf228 36
  • 56 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia C1orf228 36
  • 62 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC101733444 35
  • 61.06 (n)
  • 60.15 (a)
African clawed frog
(Xenopus laevis)
Amphibia Xl.1749 35
zebrafish
(Danio rerio)
Actinopterygii Dr.14941 35
si:ch211-241d21.5 35
  • 60.92 (n)
  • 57.5 (a)
C8H1orf228 36
  • 56 (a)
OneToOne
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.8705 35
sea squirt
(Ciona savignyi)
Ascidiacea CSA.11040 36
  • 53 (a)
OneToOne
Species with no ortholog for C1orf228:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C1orf228 Gene

ENSEMBL:
Gene Tree for C1orf228 (if available)
TreeFam:
Gene Tree for C1orf228 (if available)

Paralogs for C1orf228 Gene

No data available for Paralogs for C1orf228 Gene

Variants for C1orf228 Gene

Sequence variations from dbSNP and Humsavar for C1orf228 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs1080837 -- 44,684,578(-) ACTGG(C/G/T)TTCTT intron-variant, nc-transcript-variant, utr-variant-5-prime
rs1080838 -- 44,684,711(-) AGTGC(A/G)GGCAA intron-variant
rs1276067 -- 44,679,848(+) catct(A/G)ttttg intron-variant
rs2224403 -- 44,684,548(+) AGCAA(C/G)TGCCA intron-variant, nc-transcript-variant, utr-variant-5-prime
rs3044192 -- 44,680,167(+) GCCAA(-/GTTT)GTTTG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C1orf228 Gene

Variant ID Type Subtype PubMed ID
esv2657051 CNV Deletion 23128226
esv2662778 CNV Deletion 23128226

Variation tolerance for C1orf228 Gene

Gene Damage Index Score: 1.39; 27.44% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for C1orf228 Gene

Disorders for C1orf228 Gene

Relevant External Links for C1orf228

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C1orf228

No disorders were found for C1orf228 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C1orf228 Gene

Publications for C1orf228 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3 67

Products for C1orf228 Gene

Sources for C1orf228 Gene

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