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Aliases for C1orf220 Gene

Subcategory (RNA class) for C1orf220 Gene

ncRNA

Quality Score for this RNA gene is

13

Aliases for C1orf220 Gene

  • Chromosome 1 Open Reading Frame 220 2 3 5

External Ids for C1orf220 Gene

Previous GeneCards Identifiers for C1orf220 Gene

  • GC01P176780
  • GC01P178511
  • GC01P149739

Summaries for C1orf220 Gene

GeneCards Summary for C1orf220 Gene

C1orf220 (Chromosome 1 Open Reading Frame 220) is an RNA Gene, and is affiliated with the ncRNA class.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C1orf220 Gene

Genomics for C1orf220 Gene

Regulatory Elements for C1orf220 Gene

Enhancers for C1orf220 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01G178575 1.2 Ensembl ENCODE dbSUPER 18.1 +33.3 33252 1.3 RFX1 BHLHE40 ZNF384 TBX21 FOXM1 ZNF664 PRDM6 EGR1 EED IKZF1 C1orf220 TEX35 ENSG00000201791 GC01M178575 GC01P178569
GH01G178603 1.7 FANTOM5 Ensembl ENCODE dbSUPER 11.5 +66.5 66491 11.0 PKNOX1 NFIB ZSCAN4 RAD21 YY1 RFX5 ZNF207 RELB FOS IKZF2 RALGPS2 TEX35 C1orf220 TOR3A GC01P178598 GC01M178650
GH01G179016 1.6 Ensembl ENCODE dbSUPER 10.6 +475.1 475081 3.2 PKNOX1 FOXA2 CREB3L1 ARID4B SIN3A YY1 FOS KLF13 DEK SP5 TOR3A FAM20B C1orf220 GC01P179007
GH01G178580 1.4 FANTOM5 ENCODE dbSUPER 11.4 +38.7 38736 1.7 FOXA2 NFIB RAD21 YY1 RARA CREM IKZF2 CEBPB REST ZNF623 TEX35 C1orf220 RALGPS2 LOC105371632 GC01P178598
GH01G179002 1.2 Ensembl ENCODE 11.8 +460.8 460774 2.5 HDGF PKNOX1 RB1 ARID4B FEZF1 ZNF2 ZNF48 ZSCAN9 RAD21 YY1 C1orf220 TOR3A FAM20B GC01P179007 LOC102724754
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around C1orf220 on UCSC Golden Path with GeneCards custom track

Promoters for C1orf220 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000016338 -152 1601 MLX ZFP64 ARID4B SIN3A DMAP1 ZNF2 YY1 ZNF143 DEK ZNF263

Genomic Location for C1orf220 Gene

Chromosome:
1
Start:
178,542,752 bp from pter
End:
178,548,889 bp from pter
Size:
6,138 bases
Orientation:
Plus strand

Genomic View for C1orf220 Gene

Genes around C1orf220 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C1orf220 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C1orf220 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C1orf220 Gene

Proteins for C1orf220 Gene

  • Protein details for C1orf220 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5T0J3-CA220_HUMAN
    Recommended name:
    Putative uncharacterized protein C1orf220
    Protein Accession:
    Q5T0J3
    Secondary Accessions:
    • B2RN72
    • Q8NAD3

    Protein attributes for C1orf220 Gene

    Size:
    134 amino acids
    Molecular mass:
    15074 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C1orf220 Gene

Post-translational modifications for C1orf220 Gene

No Post-translational modifications

No data available for DME Specific Peptides for C1orf220 Gene

Domains & Families for C1orf220 Gene

Protein Domains for C1orf220 Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C1orf220: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C1orf220 Gene

Function for C1orf220 Gene

genes like me logo Genes that share phenotypes with C1orf220: view

Animal Model Products

Inhibitory RNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C1orf220 Gene

Localization for C1orf220 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C1orf220 gene
Compartment Confidence
mitochondrion 2
plasma membrane 1
extracellular 1
peroxisome 1
nucleus 1
cytosol 1
golgi apparatus 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C1orf220 Gene

Pathways & Interactions for C1orf220 Gene

SuperPathways for C1orf220 Gene

No Data Available

Interacting Proteins for C1orf220 Gene

Gene Ontology (GO) - Biological Process for C1orf220 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C1orf220 Gene

Drugs & Compounds for C1orf220 Gene

No Compound Related Data Available

Transcripts for C1orf220 Gene

mRNA/cDNA for C1orf220 Gene

(1) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(34) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for C1orf220 Gene

Chromosome 1 open reading frame 220:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for C1orf220 Gene

No ASD Table

Relevant External Links for C1orf220 Gene

GeneLoc Exon Structure for
C1orf220
ECgene alternative splicing isoforms for
C1orf220

Expression for C1orf220 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for C1orf220 Gene

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C1orf220 Gene



NURSA nuclear receptor signaling pathways regulating expression of C1orf220 Gene:

C1orf220

SOURCE GeneReport for Unigene cluster for C1orf220 Gene:

Hs.668085
genes like me logo Genes that share expression patterns with C1orf220: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for C1orf220 Gene

Orthologs for C1orf220 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for C1orf220 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C1orf220 35
  • 98 (a)
OneToOne
Species where no ortholog for C1orf220 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C1orf220 Gene

ENSEMBL:
Gene Tree for C1orf220 (if available)
TreeFam:
Gene Tree for C1orf220 (if available)

Paralogs for C1orf220 Gene

No data available for Paralogs for C1orf220 Gene

Variants for C1orf220 Gene

Sequence variations from dbSNP and Humsavar for C1orf220 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs1001530267 -- 178,544,413(+) GAGTA(C/G)ATGTT intron-variant
rs1001995434 -- 178,548,976(+) TTTAA(A/G)GGGCT downstream-variant-500B
rs1002127270 -- 178,545,017(+) GGGCC(A/T)GTGGG intron-variant
rs1002729592 -- 178,546,695(+) AGATT(G/T)TTCTT intron-variant
rs1003224217 -- 178,541,882(+) TTCTT(C/T)CCAGG upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for C1orf220 Gene

Variant ID Type Subtype PubMed ID
nsv527862 CNV loss 19592680

Relevant External Links for C1orf220 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
C1orf220

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for C1orf220 Gene

Disorders for C1orf220 Gene

Relevant External Links for C1orf220

Genetic Association Database (GAD)
C1orf220
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C1orf220

No disorders were found for C1orf220 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C1orf220 Gene

Publications for C1orf220 Gene

  1. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 2 3 64
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  3. Discovery and refinement of loci associated with lipid levels. (PMID: 24097068) . … Abecasis G.R. (Nat. Genet. 2013) 3 64
  4. A genome-wide association for kidney function and endocrine-related traits in the NHLBI's Framingham Heart Study. (PMID: 17903292) Hwang S.J. … Fox C.S. (BMC Med. Genet. 2007) 46 64
  5. Genome-wide association with select biomarker traits in the Framingham Heart Study. (PMID: 17903293) Benjamin E.J. … Vasan R.S. (BMC Med. Genet. 2007) 46 64

Products for C1orf220 Gene

Sources for C1orf220 Gene

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