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Aliases for C1orf216 Gene

Aliases for C1orf216 Gene

  • Chromosome 1 Open Reading Frame 216 2 3

External Ids for C1orf216 Gene

Summaries for C1orf216 Gene

GeneCards Summary for C1orf216 Gene

C1orf216 (Chromosome 1 Open Reading Frame 216) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C1orf216 Gene

Genomics for C1orf216 Gene

Genomic Location for C1orf216 Gene

Start:
35,713,875 bp from pter
End:
35,719,472 bp from pter
Size:
5,598 bases
Orientation:
Minus strand

Genomic View for C1orf216 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for C1orf216 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C1orf216 Gene

Regulatory Elements for C1orf216 Gene

Proteins for C1orf216 Gene

  • Protein details for C1orf216 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8TAB5-CA216_HUMAN
    Recommended name:
    UPF0500 protein C1orf216
    Protein Accession:
    Q8TAB5
    Secondary Accessions:
    • D3DPS1
    • Q8N8N6

    Protein attributes for C1orf216 Gene

    Size:
    229 amino acids
    Molecular mass:
    24968 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAC04799.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for C1orf216 Gene

Proteomics data for C1orf216 Gene at MOPED

Post-translational modifications for C1orf216 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C1orf216 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C1orf216 Gene

Domains for C1orf216 Gene

Protein Domains for C1orf216 Gene

InterPro:
ProtoNet:

UniProtKB/Swiss-Prot:

CA216_HUMAN
Family:
  • Belongs to the UPF0500 family.:
    • Q8TAB5
genes like me logo Genes that share domains with C1orf216: view

No data available for Gene Families for C1orf216 Gene

Function for C1orf216 Gene

Gene Ontology (GO) - Molecular Function for C1orf216 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 16189514
genes like me logo Genes that share ontologies with C1orf216: view

miRNA for C1orf216 Gene

miRTarBase miRNAs that target C1orf216

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for C1orf216 Gene

Localization for C1orf216 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for C1orf216 Gene COMPARTMENTS Subcellular localization image for C1orf216 gene
Compartment Confidence
cytosol 2
nucleus 2
extracellular 1

No data available for Gene Ontology (GO) - Cellular Components for C1orf216 Gene

Pathways for C1orf216 Gene

SuperPathways for C1orf216 Gene

No Data Available

Gene Ontology (GO) - Biological Process for C1orf216 Gene

None

No data available for Pathways by source for C1orf216 Gene

Transcripts for C1orf216 Gene

mRNA/cDNA for C1orf216 Gene

Unigene Clusters for C1orf216 Gene

Chromosome 1 open reading frame 216:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for C1orf216 Gene

ExUns: 1a · 1b ^ 2 ^ 3a · 3b
SP1:
SP2: -

Relevant External Links for C1orf216 Gene

GeneLoc Exon Structure for
C1orf216
ECgene alternative splicing isoforms for
C1orf216

Expression for C1orf216 Gene

mRNA expression in normal human tissues for C1orf216 Gene

mRNA differential expression in normal tissues according to GTEx for C1orf216 Gene

This gene is overexpressed in Brain - Cortex (4.4) and Brain - Frontal Cortex (BA9) (4.2).

SOURCE GeneReport for Unigene cluster for C1orf216 Gene Hs.112023

genes like me logo Genes that share expressions with C1orf216: view

Orthologs for C1orf216 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C1orf216 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C1H1orf216 36
  • 99.71 (n)
  • 99.13 (a)
C1orf216 37
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia C1orf216 37
  • 85 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C15H1orf216 36
  • 84.21 (n)
  • 84.65 (a)
C1orf216 37
  • 85 (a)
OneToOne
mouse
(Mus musculus)
Mammalia 5730409E04Rik 36
  • 83.04 (n)
  • 83.33 (a)
5730409E04Rik 16
5730409E04Rik 37
  • 83 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia C1orf216 37
  • 55 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia LOC100912566 36
  • 83.04 (n)
  • 82.14 (a)
chicken
(Gallus gallus)
Aves C1ORF216 36
  • 65.17 (n)
  • 58.5 (a)
C1orf216 37
  • 48 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia C1orf216 37
  • 54 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia c1orf216 36
  • 53.24 (n)
  • 50 (a)
zebrafish
(Danio rerio)
Actinopterygii C1orf216 37
  • 22 (a)
OneToOne
Species with no ortholog for C1orf216:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C1orf216 Gene

ENSEMBL:
Gene Tree for C1orf216 (if available)
TreeFam:
Gene Tree for C1orf216 (if available)

Paralogs for C1orf216 Gene

No data available for Paralogs for C1orf216 Gene

Variants for C1orf216 Gene

Sequence variations from dbSNP and Humsavar for C1orf216 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs1053755 -- 35,713,992(-) ATCCA(A/G)AGAGT utr-variant-3-prime
rs3179908 -- 35,713,876(-) AATTA(A/C)ATTTC utr-variant-3-prime
rs3795501 -- 35,715,371(-) TGTGT(A/G)TGTAG utr-variant-3-prime
rs6658453 -- 35,720,505(+) AGTGC(A/G)GTGGC upstream-variant-2KB
rs6669654 -- 35,720,511(+) GTGGC(A/G)CAATC upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for C1orf216 Gene

Variant ID Type Subtype PubMed ID
nsv871396 CNV Gain 21882294
nsv834680 CNV Gain 17160897

Relevant External Links for C1orf216 Gene

HapMap Linkage Disequilibrium report
C1orf216

Disorders for C1orf216 Gene

No disorders were found for C1orf216 Gene.

No data available for UniProtKB/Swiss-Prot for C1orf216 Gene

Publications for C1orf216 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. Towards a proteome-scale map of the human protein-protein interaction network. (PMID: 16189514) Rual J.F. … Vidal M. (Nature 2005) 3
  4. The palmitoyl acyltransferase HIP14 shares a high proportion of interactors with huntingtin: implications for a role in the pathogenesis of Huntington's disease. (PMID: 24705354) Butland S.L. … Hayden M.R. (Hum. Mol. Genet. 2014) 3
  5. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3

Products for C1orf216 Gene

Sources for C1orf216 Gene

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