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Aliases for C1orf210 Gene

Aliases for C1orf210 Gene

  • Chromosome 1 Open Reading Frame 210 2 3
  • TEMP 3 4

External Ids for C1orf210 Gene

Previous GeneCards Identifiers for C1orf210 Gene

  • GC01M043520
  • GC01M043747
  • GC01M041867

Summaries for C1orf210 Gene

GeneCards Summary for C1orf210 Gene

C1orf210 (Chromosome 1 Open Reading Frame 210) is a Protein Coding gene.

UniProtKB/Swiss-Prot for C1orf210 Gene

  • May be involved in membrane trafficking between endosomes and plasma membrane

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C1orf210 Gene

Genomics for C1orf210 Gene

Regulatory Elements for C1orf210 Gene

Genomic Location for C1orf210 Gene

Chromosome:
1
Start:
43,281,865 bp from pter
End:
43,285,840 bp from pter
Size:
3,976 bases
Orientation:
Minus strand

Genomic View for C1orf210 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for C1orf210 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C1orf210 Gene

Proteins for C1orf210 Gene

  • Protein details for C1orf210 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8IVY1-CA210_HUMAN
    Recommended name:
    Type III endosome membrane protein TEMP
    Protein Accession:
    Q8IVY1
    Secondary Accessions:
    • D3DPX2

    Protein attributes for C1orf210 Gene

    Size:
    113 amino acids
    Molecular mass:
    12024 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C1orf210 Gene

Proteomics data for C1orf210 Gene at MOPED

Post-translational modifications for C1orf210 Gene

  • Glycosylation at Asn 5
  • Modification sites at PhosphoSitePlus

Other Protein References for C1orf210 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C1orf210 Gene

Domains & Families for C1orf210 Gene

Protein Domains for C1orf210 Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C1orf210: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C1orf210 Gene

Function for C1orf210 Gene

Molecular function for C1orf210 Gene

UniProtKB/Swiss-Prot Function:
May be involved in membrane trafficking between endosomes and plasma membrane
genes like me logo Genes that share phenotypes with C1orf210: view

Animal Model Products

CRISPR Products

miRNA for C1orf210 Gene

miRTarBase miRNAs that target C1orf210

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , Transcription Factor Targets and HOMER Transcription for C1orf210 Gene

Localization for C1orf210 Gene

Subcellular locations from UniProtKB/Swiss-Prot for C1orf210 Gene

Membrane; Single-pass type III membrane protein. Early endosome. Recycling endosome. Cell membrane. Note=Also localizes to tubular endosome structures. {ECO:0000250 UniProtKB:Q9CQM1}.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for C1orf210 Gene COMPARTMENTS Subcellular localization image for C1orf210 gene
Compartment Confidence
endosome 3
plasma membrane 3

Gene Ontology (GO) - Cellular Components for C1orf210 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005769 early endosome IEA --
GO:0005886 plasma membrane IEA --
GO:0016021 integral component of membrane IEA --
GO:0055037 recycling endosome IEA --
genes like me logo Genes that share ontologies with C1orf210: view

Pathways & Interactions for C1orf210 Gene

SuperPathways for C1orf210 Gene

No Data Available

Interacting Proteins for C1orf210 Gene

Gene Ontology (GO) - Biological Process for C1orf210 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0002230 positive regulation of defense response to virus by host IMP 22020285
genes like me logo Genes that share ontologies with C1orf210: view

No data available for Pathways by source and SIGNOR curated interactions for C1orf210 Gene

Drugs & Compounds for C1orf210 Gene

No Compound Related Data Available

Transcripts for C1orf210 Gene

mRNA/cDNA for C1orf210 Gene

(3) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(20) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for C1orf210 Gene

Chromosome 1 open reading frame 210:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C1orf210

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C1orf210 Gene

No ASD Table

Relevant External Links for C1orf210 Gene

GeneLoc Exon Structure for
C1orf210
ECgene alternative splicing isoforms for
C1orf210

Expression for C1orf210 Gene

mRNA expression in normal human tissues for C1orf210 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for C1orf210 Gene

This gene is overexpressed in Colon - Transverse (x7.8), Kidney - Cortex (x5.0), Pancreas (x4.7), and Stomach (x4.6).

Protein differential expression in normal tissues from HIPED for C1orf210 Gene

This gene is overexpressed in Fetal Liver (27.0), Pancreas (16.7), Colon (15.5), and Rectum (9.8).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C1orf210 Gene



SOURCE GeneReport for Unigene cluster for C1orf210 Gene Hs.158963

genes like me logo Genes that share expression patterns with C1orf210: view

Protein tissue co-expression partners for C1orf210 Gene

Primer Products

In Situ Assay Products

No data available for mRNA Expression by UniProt/SwissProt for C1orf210 Gene

Orthologs for C1orf210 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C1orf210 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia C3H1orf210 35
  • 81.12 (n)
  • 72.57 (a)
C3H1ORF210 36
  • 73 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C15H1orf210 35
  • 80.56 (n)
  • 73.15 (a)
C1orf210 36
  • 73 (a)
OneToOne
mouse
(Mus musculus)
Mammalia 2610528J11Rik 35
  • 80.06 (n)
  • 77.57 (a)
2610528J11Rik 16
2610528J11Rik 36
  • 75 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia C1H1orf210 35
  • 99.71 (n)
  • 100 (a)
C1orf210 36
  • 100 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia RGD1305347 35
  • 80.67 (n)
  • 78 (a)
oppossum
(Monodelphis domestica)
Mammalia C1orf210 36
  • 51 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii C6H1orf210 36
  • 15 (a)
OneToOne
Species with no ortholog for C1orf210:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C1orf210 Gene

ENSEMBL:
Gene Tree for C1orf210 (if available)
TreeFam:
Gene Tree for C1orf210 (if available)

Paralogs for C1orf210 Gene

No data available for Paralogs for C1orf210 Gene

Variants for C1orf210 Gene

Sequence variations from dbSNP and Humsavar for C1orf210 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs1198976 -- 43,282,461(+) GAATA(A/G)CATTG utr-variant-3-prime
rs1763696 -- 43,282,380(-) TCTTC(C/T)CCTAA utr-variant-3-prime
rs2784466 -- 43,286,306(-) GATAA(C/G/T)GAGGA upstream-variant-2KB
rs2991342 -- 43,285,169(+) TACTA(C/G)GTCCG intron-variant
rs3120123 -- 43,284,084(+) CTGAA(G/T)CAGGA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C1orf210 Gene

Variant ID Type Subtype PubMed ID
nsv829693 CNV Loss 17160897

Variation tolerance for C1orf210 Gene

Residual Variation Intolerance Score: 68.35% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.18; 39.49% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C1orf210 Gene

HapMap Linkage Disequilibrium report
C1orf210

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C1orf210 Gene

Disorders for C1orf210 Gene

Relevant External Links for C1orf210

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C1orf210
genes like me logo Genes that share disorders with C1orf210: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C1orf210 Gene

Publications for C1orf210 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 67
  2. Image-based genome-wide siRNA screen identifies selective autophagy factors. (PMID: 22020285) Orvedahl A. … Levine B. (Nature 2011) 67
  3. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P. … Vidal M. (Genomics 2007) 67
  4. Transcriptome analysis of human gastric cancer. (PMID: 16341674) Oh J.H. … Kim N.S. (Mamm. Genome 2005) 67
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 67

Products for C1orf210 Gene

Sources for C1orf210 Gene

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