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Aliases for C1orf204 Gene

Aliases for C1orf204 Gene

  • Chromosome 1 Open Reading Frame 204 2 3 5
  • VSIG8 4

External Ids for C1orf204 Gene

Previous GeneCards Identifiers for C1orf204 Gene

  • GC01U901196
  • GC01M158071
  • GC01M131160

Summaries for C1orf204 Gene

GeneCards Summary for C1orf204 Gene

C1orf204 (Chromosome 1 Open Reading Frame 204) is a Protein Coding gene. GO annotations related to this gene include poly(A) RNA binding. An important paralog of this gene is VSIG8.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C1orf204 Gene

Genomics for C1orf204 Gene

Regulatory Elements for C1orf204 Gene

Enhancers for C1orf204 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01F159828 1.4 FANTOM5 Ensembl ENCODE 34.2 +25.3 25321 2.7 CTCF ARNT ZNF2 ZNF644 RAD21 ZNF143 SMC3 FOS ZNF600 MAZ C1orf204 SLAMF8 SLAMF9 GC01M159841
GH01F159908 1.9 FANTOM5 Ensembl ENCODE 18.7 -62.1 -62137 18.5 HDGF PKNOX1 WRNIP1 SIN3A YBX1 FEZF1 ZNF2 YY1 ZNF143 ZNF207 ENSG00000228606 ENSG00000272668 C1orf204 VSIG8 SLAMF8 LINC01133 TAGLN2 FCRL6 NCSTN DCAF8
GH01F159935 1.7 FANTOM5 Ensembl ENCODE 18.6 -86.0 -85975 10.8 HDGF PKNOX1 CREB3L1 SIN3A FEZF1 ZNF2 YY1 ZNF143 FOS ZNF263 ATP1A4 LINC01133 C1orf204 ENSG00000272668 ENSG00000228606 IGSF9 NHLH1 VSIG8 CFAP45 VANGL2
GH01F160341 1.1 ENCODE 27.2 -487.7 -487693 3.3 HDGF PKNOX1 ARNT CREB3L1 WRNIP1 ARID4B SIN3A DMAP1 ZNF2 YY1 NCSTN ENSG00000272668 C1orf204 RPSAP18 COPA GC01M160326 ENSG00000202078
GH01F159888 1.6 FANTOM5 Ensembl ENCODE 16.3 -35.1 -35054 3.2 HDGF TBP ATF1 KLF17 PTRF SIN3A ZNF2 RAD21 RFX5 GLIS2 ENSG00000272668 VSIG8 SLAMF8 C1orf204 FCRL6 ENSG00000212161 IGSF9 DUSP23 PIGM SLAMF9
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around C1orf204 on UCSC Golden Path with GeneCards custom track

Promoters for C1orf204 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000546148 547 1601 ATF1 SIN3A BRCA1 RARA GLIS2 ZNF366 RCOR1 EGR2 SMARCC1 SP3

Genomic Location for C1orf204 Gene

159,834,474 bp from pter
159,855,347 bp from pter
20,874 bases
Minus strand

Genomic View for C1orf204 Gene

Genes around C1orf204 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C1orf204 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C1orf204 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C1orf204 Gene

Proteins for C1orf204 Gene

  • Protein details for C1orf204 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    V-set and immunoglobulin domain-containing protein 8
    Protein Accession:
    Secondary Accessions:
    • Q5VU14

    Protein attributes for C1orf204 Gene

    414 amino acids
    Molecular mass:
    43891 Da
    Quaternary structure:
    No Data Available
    • Sequence=AK096506; Type=Erroneous termination; Positions=409; Note=Translated as Lys.; Evidence={ECO:0000305};

    Alternative splice isoforms for C1orf204 Gene


neXtProt entry for C1orf204 Gene

Post-translational modifications for C1orf204 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C1orf204 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C1orf204 Gene

Domains & Families for C1orf204 Gene

Protein Domains for C1orf204 Gene

Graphical View of Domain Structure for InterPro Entry



  • Contains 2 Ig-like V-type (immunoglobulin-like) domains.
  • Contains 2 Ig-like V-type (immunoglobulin-like) domains.
genes like me logo Genes that share domains with C1orf204: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for C1orf204 Gene

Function for C1orf204 Gene

Gene Ontology (GO) - Molecular Function for C1orf204 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0044822 poly(A) RNA binding IDA --
genes like me logo Genes that share ontologies with C1orf204: view

Animal Model Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for C1orf204 Gene

Localization for C1orf204 Gene

Subcellular locations from UniProtKB/Swiss-Prot for C1orf204 Gene

Membrane; Single-pass type I membrane protein.

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C1orf204 gene
Compartment Confidence
mitochondrion 3
nucleus 2
extracellular 1

Gene Ontology (GO) - Cellular Components for C1orf204 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with C1orf204: view

Pathways & Interactions for C1orf204 Gene

SuperPathways for C1orf204 Gene

No Data Available

Interacting Proteins for C1orf204 Gene

Selected Interacting proteins: Q5VU13-VSIG8_HUMAN for C1orf204 Gene via IID

Gene Ontology (GO) - Biological Process for C1orf204 Gene


No data available for Pathways by source and SIGNOR curated interactions for C1orf204 Gene

Transcripts for C1orf204 Gene

mRNA/cDNA for C1orf204 Gene

(1) REFSEQ mRNAs :
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C1orf204 Gene

No ASD Table

Relevant External Links for C1orf204 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C1orf204 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for C1orf204 Gene

mRNA differential expression in normal tissues according to GTEx for C1orf204 Gene

This gene is overexpressed in Skin - Not Sun Exposed (Suprapubic) (x4.1).

Protein differential expression in normal tissues from HIPED for C1orf204 Gene

This gene is overexpressed in Hair follicle (39.0), Bone marrow mesenchymal stem cell (15.7), and Plasma (11.1).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C1orf204 Gene

Protein tissue co-expression partners for C1orf204 Gene

NURSA nuclear receptor signaling pathways regulating expression of C1orf204 Gene:

genes like me logo Genes that share expression patterns with C1orf204: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for C1orf204 Gene

Orthologs for C1orf204 Gene

Evolution for C1orf204 Gene

Gene Tree for C1orf204 (if available)
Gene Tree for C1orf204 (if available)

No data available for Orthologs for C1orf204 Gene

Paralogs for C1orf204 Gene

Paralogs for C1orf204 Gene

genes like me logo Genes that share paralogs with C1orf204: view

Variants for C1orf204 Gene

Sequence variations from dbSNP and Humsavar for C1orf204 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs111439060 -- 159,855,045(+) CAGGC(C/G)GGCGG intron-variant, upstream-variant-2KB
rs111455938 -- 159,835,441(+) CAGCA(C/T)GTTTC intron-variant, downstream-variant-500B, utr-variant-3-prime
rs111861505 -- 159,856,771(+) ACACC(-/CA/CACA)CACAC intron-variant, upstream-variant-2KB
rs111960068 -- 159,834,007(+) CCAGT(C/G)GCTGA intron-variant, downstream-variant-500B
rs112023946 -- 159,839,762(+) CCTGG(A/C)CTGTA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C1orf204 Gene

Variant ID Type Subtype PubMed ID
esv3587702 CNV loss 21293372
esv3587703 CNV gain 21293372
nsv1005195 CNV gain 25217958

Variation tolerance for C1orf204 Gene

Gene Damage Index Score: 2.28; 40.79% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C1orf204 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C1orf204 Gene

Disorders for C1orf204 Gene

Relevant External Links for C1orf204

Genetic Association Database (GAD)
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for C1orf204 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C1orf204 Gene

Publications for C1orf204 Gene

  1. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PMID: 15815621) Hillier L.W. … Wilson R.K. (Nature 2005) 3 4 64
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  4. A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants. (PMID: 17463248) Scott L.J. … Boehnke M. (Science 2007) 46 64

Products for C1orf204 Gene

Sources for C1orf204 Gene

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