C1orf198 Gene
protein-coding GIFtS : 39
GCID: GC01 M230972
chromosome 1 open reading frame 198
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Aliasesfor C1orf198 gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc ,
7 Ensembl ,
8 DME ,
9 miRBase ,
and/or 10 fRNAdb )About This Section Aliases Chromosome 1 Open Reading Frame 198 1 2 FLJ388471 DKFZp667D1521 MGC107101 FLJ145251 Uncharacterized Protein C1orf1982 FLJ162831
Export aliases for C1orf198 gene to outside databases Previous GC identifers: GC01M229039 GC01M201457
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Summariesfor C1orf198 gene (According to Entrez Gene ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
PharmGKB ,
UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
About This Section --
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Genomic Viewsfor C1orf198 gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,
and/or miRBase ,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69) ,
Regulatory elements and Epigenetics data according to
QIAGEN ,
SABiosciences , and/or
SwitchGear Genomics )About This Section RefSeq DNA sequence: NC_000001.10 NC_018912.1 NT_167186.1 Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the C1orf198 gene promoter: USF1 USF-1 USF-1:USF-2 GCNF-2 Other transcription factors Search SABiosciences Chromatin IP Primers for C1orf198 Epigenetics: QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C1orf198
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 1q42.2 Ensembl cytogenetic band: 1q42.2 HGNC cytogenetic band: 1q42.2 C1orf198 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different) GeneLoc information about chromosome 1 GeneLoc Exon Structure
GeneLoc location for GC01M230972: view genomic region
(about GC identifiers )
Start:
230,972,865 bp from pter
End:
231,005,335 bp from pter
Size:
32,471 bases
Orientation:
minus strand
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Proteinsfor C1orf198 gene
(According to
1 UniProtKB ,
HORDE ,
neXtProt ,
Ensembl ,
and/or Reactome ,
Modification sites according to 2 PhosphoSitePlus ,
Specific Peptides from DME ,
Protein expression images according to data from SPIRE MOPED and PaxDb ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
EMD Millipore ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological ,
ProSpec , and/or
Uscn ,
Biochemical Assays by
EMD Millipore ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Uscn ,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene ,
Antibodies by
EMD Millipore ,
R&D Systems ,
GenScript ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals ,
Thermo Fisher Scientific ,
Abcam , and/or
Uscn )
About This Section UniProtKB/Swiss-Prot: CA198_HUMAN, Q9H425 (See
protein sequence )Recommended Name: Uncharacterized protein C1orf198 Size : 327 amino acids; 36346 Da
Subcellular location : Cytoplasm
Secondary accessions : A8K8R8Alternative splicing : 2 isoforms : Q9H425-1 Q9H425-2 Explore the universe of human proteins at neXtProt for C1orf198: NX_Q9H425 Post-translational modifications:
View modification sites using PhosphoSitePlus 2 View neXtProt modification sites for NX_Q9H425 C1orf198 Protein expression data from MOPED and PaxDb : About this image REFSEQ proteins (3 alternative transcripts):
NP_001129966.1 NP_001129967.1 NP_116189.1 ENSEMBL proteins: ENSP00000355623 ENSP00000428172 ENSP00000411384 ENSP00000430967 ENSP00000429503 Human Recombinant Protein Products for C1orf198: Gene Ontology (GO): 1 cellular component term (GO ID links to tree view) : About this table
GO ID Qualified GO term Evidence PubMed IDs GO:0005737 cytoplasm
IEA --
C1orf198 for ontologies About GeneDecksing C1orf198 Antibody Products: Assay Products for C1orf198:
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Protein
Domains / Familiesfor C1orf198 gene (According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
About This Section ProtoNet protein and cluster: Q9H425
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Functionfor C1orf198 gene
(According to 1 UniProtKB ,
Genatlas ,
LifeMap Discovery™ ,
IUBMB , and/or
2 DME ,
Human phenotypes from GenomeRNAi ,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory ,
bound targets from SABiosciences ,
miRNA Gene Targets from miRTarBase ,
shRNA from
OriGene ,
Sirion Biotech ,
RNAi from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
microRNA from QIAGEN ,
Gene Editing from DNA2.0 ,
Sirion Biotech ,
Clones from EMD Millipore ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
Sino Biological ,
DNA2.0 ,
and Vector BioLabs ,
Cell Lines from GenScript ,
LifeMap BioReagents ,
Sirion Biotech ,
In Situ Hybridization Assays from Advanced Cell Diagnostics ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene .)
About This Section Phenotypes: 5 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for 2310022B05Rik) :
C1orf198 for phenotypes About GeneDecksing Animal Models: Clone Products: Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for C1orf198 (see all 4 ) OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for C1orf198 (see all 3 )OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector (see all 3 ): C1orf198 (NM_032800 ) Browse Sino Biological Human cDNA Clones DNA2.0 Custom Codon Optimized Gene
Synthesis Service for C1orf198 Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat C1orf198
In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C1orf198
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Pathways & Interactionsfor C1orf198 gene
(Pathways according to
EMD Millipore ,
R&D Systems ,
Cell Signaling Technology ,
KEGG ,
PharmGKB ,
BioSystems ,
Reactome ,
Tocris Bioscience ,
GeneGo (Thomson Reuters) ,
QIAGEN ,
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Interaction Networks according to
SABiosciences ,
and/or STRING ,
Interactions according to 1 UniProtKB ,
2 MINT ,
3 I2D , and/or
4 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene) .
About This Section Interactions: Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for C1orf198 STRING Interaction
Network Preview (showing 2 interactants - click image to see more details)2 Interacting proteins for C1orf198 (ENSP00000355623 4 ) via UniProtKB, MINT, STRING , and/or I2D About this table
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Drugs & Compoundsfor C1orf198 gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
EMD Millipore , Tocris Bioscience
HMDB ,
BitterDB , and/or
Novoseek , and Drugs according to
DrugBank ,
Enzo Life Sciences , and/or
PharmGKB , with drugs/clinical trials/news
search links to CenterWatch )
About This Section Browse Tocris compounds for C1orf198 Search CenterWatch for drugs/clinical trials and news about C1orf198 / CA198
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Transcriptsfor C1orf198 gene (Secondary structures according to
fRNAdb ,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank , RefSeq according to Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,
RNAi Products from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
shRNA from
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Sirion Biotech ,
microRNA from QIAGEN ,
Tagged/untagged cDNA clones from
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SwitchGear Genomics ,
GenScript ,
DNA2.0 ,
Vector BioLabs ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN
)About This Section REFSEQ mRNAs for C1orf198 gene (3 alternative transcripts): NM_001136494.1 NM_001136495.1 NM_032800.2 Unigene Cluster for C1orf198:
Chromosome 1 open reading frame 198 Hs.520494 [show with all ESTs ] Unigene Representative Sequence: NM_001136494 7 Ensembl transcripts including schematic representations, and UCSC links where relevant : ENST00000366663 (uc001hub.3 ) ENST00000470540 (uc009xfh.2 uc001hud.2 )ENST00000427697 (uc001huc.2 ) ENST00000523410 ENST00000522201 ENST00000519360 ENST00000521263 Clone Products: OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for C1orf198 (see all 4 ) OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for C1orf198 (see all 3 )OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector (see all 3 ): C1orf198 (NM_032800 ) DNA2.0 Custom Codon Optimized Gene
Synthesis Service for C1orf198 Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat C1orf198
Additional cDNA sequence: AK027431.1 AK096166.1 AK131306.1 AK292433.1 AL713769.1 AL833809.1 BC004870.2 BC066649.1
12 DOTS entries : DT.446154 DT.95332138
DT.100036713 DT.100650433 DT.95260947 DT.102827966 DT.121393703 DT.91735382 DT.100650432 DT.102827964 DT.121393766 DT.95135584 24/292 AceView cDNA sequences (see all 292 ):
AI335701 BC066649 BX955468 AA425751 BP343371 CB265680 AA291594 NM_032800 AI081780 BU727962 AA433899 AA476334 BQ717451 AA863265 AA293642 BQ024373 BE047855 BM127465 BM664998 BM750995 AW070537 AI218045 BX399779 AA434218 GeneLoc Exon Structure 5/7 Alternative Splicing Database (ASD) splice patterns (SP) for C1orf198 (see all 7 ) About this scheme ExUns: 1a · 1b ^ 2 ^ 3a · 3b · 3c ^ 4a · 4b · 4c ^ 5a · 5b ^ 6 ^ 7a · 7b · 7c · 7d · 7e ^ 8 SP1 :     -   -     -   -       -   -                 SP2 :       -     -   -   -   -   -   -   -   -             SP3 :           -   -   -     -   -                 SP4 :                   -   -                 SP5 :                                    
ECgene alternative splicing isoforms for C1orf198
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Expression for C1orf198 gene
(RNA expression data according to
H-InvDB ,
NONCODE ,
miRBase , and
RNAdb ,
Expression images according to data from
BioGPS ,
Illumina Human BodyMap , and
CGAP
SAGE ,
Sets of similar genes according to GeneDecks ,
in vivo and in vitro expression data from LifeMap Discovery™ ,
plus additional links to
Genevestigator , and/or
SOURCE , and/or
BioGPS , and/or
UniProtKB ,
PCR Arrays from
SABiosciences ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN ,
In Situ Hybridization Assays from Advanced Cell Diagnostics )
About This Section C1orf198 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this image BioGPS CGAP TAG: ATTTTGGATTAbout this image C1orf198 expression in embryonic tissues and stem cells Expression by the Database of Embryonic development, Stem cell research, and
Regenerative medicine About this table
See C1orf198 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for C1orf198 SOURCE GeneReport for Unigene cluster: Hs.520494 SABiosciences Custom PCR Arrays for C1orf198 Primer Products: OriGene genome-wide validated SYBR primer pairs in human , mouse , rat for C1orf198Browse OriGene validated miRNA SYBR primer pairs SABiosciences RT2 qPCR Primer Assay in human , mouse , rat C1orf198 QIAGEN QuantiTect SYBR Green Assays in human , mouse , rat C1orf198 QIAGEN QuantiFast Probe-based Assays in human , mouse , rat C1orf198 In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C1orf198
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Orthologsfor C1orf198 gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
,
5 MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase ,
and/or
6 Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam )
About This Section
This gene was present in the common ancestor of animals.
Orthologs for C1orf198 gene from 5/13 species (see all 13 ) About this table
ENSEMBL Gene Tree for C1orf198 (if available)TreeFam Gene Tree for C1orf198 (if available)
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Paralogsfor C1orf198 gene (Paralogs according to
1 HomoloGene , 2 Ensembl , and 3 SIMAP , Pseudogenes according to 4 Pseudogene.org Build 68)About This Section --
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Genomic Variantsfor C1orf198 gene (SNPs/Variants according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE ,
UniProtKB , and
DNA2.0 ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB) , Blood group antigen gene mutations by BGMUT ,
Resequencing Primers from QIAGEN ,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences )
About This Section
Genomic Data Transcription Related Data Allele Frequencies SNP ID Valid Clinical significance Chr 1 pos Sequence # AA Chg Type More # Allele freq Pop Total sample More
HapMap Linkage Disequilibrium report for C1orf198 (230972865 - 231005335 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV) variations for C1orf198: --
SABiosciences Cancer Mutation PCR Assays
QIAGEN SeqTarget long-range PCR primers in human , mouse , rat for resequencing C1orf198
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Disorders
/ Diseasesfor C1orf198 gene
(in which this Gene is Involved, According to MalaCards ,
OMIM, UniProtKB ,
the University of Copenhagen DISEASES
database ,
Genatlas , GeneTests ,
GAD ,
HuGE Navigator ,
and/or TGDB .)
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Publicationsfor C1orf198 gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 HMDB ,
7 DrugBank ,
8 UniProtKB/TrEMBL ,
9 Novoseek , and/or
10 fRNAdb )
About This Section PubMed articles for C1orf198 gene, integrated from 9 sources (see all 12 ): (articles sorted by number of sources associating them with C1orf198) Utopia : connect your pdf to the dynamic world of online information
The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414) 1 , 2 Gregory S.G.... Bentley D.R. (2006) The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334) 1 , 2 Gerhard D.S....Malek J. (2004) Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039) 1 , 2 Ota T.... Sugano S. (2004) Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides. (PubMed id 12665801) 1 , 2 Gevaert K.... Vandekerckhove J. (2003) Systematic validation of antibody binding and protein subcellular localization using siRNA and confocal microscopy. (PubMed id 22361696) 2 Stadler C.... Lundberg E. (2012) Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983) 1 Kim W....Gygi S.P. (2011) Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048) 1 Danielsen J.M....Nielsen M.L. (2011) Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332) 2 Mayya V.... Han D.K. (2009) Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201) 1 Abdelmohsen K....Gorospe M. (2009) Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis. (PubMed id 18220336) 2 Cantin G.T....Yates J.R. III (2008)
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External Searches for C1orf198 gene
(in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section
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Genome Databases showing C1orf198 gene
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
Kegg ,
and/or
H-InvDB )
About This Section
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Other Databases showing C1orf198 gene
(According to HUGE )
About This Section --
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Specialized Databases showing C1orf198 gene (According to PharmGKB ,
ATLAS , HORDE , IMGT , LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
Name Description
PharmGKB entry for C1orf198 Pharmacogenomics, SNPs, Pathways
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About This Section Patent Information for C1orf198 gene: Search GeneIP for patents involving C1orf198 GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Productsfor C1orf198 gene (Antibodies, recombinant proteins, and assays from EMD Millipore , R&D Systems , OriGene , QIAGEN , GenScript , Cell Signaling Technology , SABiosciences , Novus Biologicals , Sino Biological , Enzo Life Sciences , Abcam , ProSpec , Uscn , Thermo Fisher Scientific , Gene Editing from DNA2.0 and Sirion Biotech , Clones from EMD Millipore , OriGene , GenScript , Sino Biological , DNA2.0 , SwitchGear Genomics , Vector BioLabs , Cell lines from GenScript , LifeMap BioReagents , and Sirion Biotech , PCR Arrays from SABiosciences , Drugs and/or compounds from EMD Millipore , Tocris Bioscience , and/or
Enzo Life Sciences , In Situ Hybridization Assays from Advanced Cell Diagnostics , Animal models from inGenious Targeting Laboratory )About This Section
Browse OriGene Antibodies OriGene shRNA RFP for C1orf198 OriGene 29mer shRNA kits in GFP-retroviral vector in human , mouse , rat for C1orf198 OriGene genome-wide validated SYBR primer pairs in human , mouse , rat for C1orf198 OriGene Protein Over-expression Lysate for C1orf198 Browse OriGene Fluorogenic Cell Assay Kits OriGene siRNA for C1orf198 OriGene 3'-UTR Clone for C1orf198 OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for C1orf198 OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for C1orf198 Browse OriGene GFP tagged cDNA clones in CMV expression vector Browse OriGene MicroRNA Expression Plasmids Browse OriGene basic RS shRNAs Browse OriGene validated miRNA SYBR primer pairs OriGene Purified Protein for C1orf198 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling OriGene Custom Antibody Services for C1orf198 OriGene Custom Protein Services for C1orf198 OriGene Custom Immunoassay Development
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat C1orf198 QIAGEN SeqTarget long-range PCR primers in human , mouse , rat for resequencing C1orf198 QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C1orf198 QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human , mouse , rat C1orf198 QIAGEN QuantiFast Probe-based Assays in human , mouse , rat C1orf198 QIAGEN QuantiTect SYBR Green Assays in human , mouse , rat C1orf198
C1orf198 Proteins, Antibodies, CLIAs, and ELISAs
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C1orf198
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Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat C1orf198
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Aliases for C1orf198
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