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Aliases for C1orf198 Gene

Aliases for C1orf198 Gene

  • Chromosome 1 Open Reading Frame 198 2 3

External Ids for C1orf198 Gene

Previous GeneCards Identifiers for C1orf198 Gene

  • GC01M229039
  • GC01M230972
  • GC01M201457

Summaries for C1orf198 Gene

GeneCards Summary for C1orf198 Gene

C1orf198 (Chromosome 1 Open Reading Frame 198) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C1orf198 Gene

Genomics for C1orf198 Gene

Regulatory Elements for C1orf198 Gene

Genomic Location for C1orf198 Gene

230,837,119 bp from pter
230,869,589 bp from pter
32,471 bases
Minus strand

Genomic View for C1orf198 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for C1orf198 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C1orf198 Gene

Proteins for C1orf198 Gene

  • Protein details for C1orf198 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized protein C1orf198
    Protein Accession:
    Secondary Accessions:
    • A8K8R8
    • B3KTW1
    • G5EA08

    Protein attributes for C1orf198 Gene

    327 amino acids
    Molecular mass:
    36346 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for C1orf198 Gene


neXtProt entry for C1orf198 Gene

Proteomics data for C1orf198 Gene at MOPED

Post-translational modifications for C1orf198 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C1orf198 Gene

No data available for DME Specific Peptides for C1orf198 Gene

Domains & Families for C1orf198 Gene

Protein Domains for C1orf198 Gene


Suggested Antigen Peptide Sequences for C1orf198 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C1orf198: view

No data available for Gene Families and UniProtKB/Swiss-Prot for C1orf198 Gene

Function for C1orf198 Gene

Phenotypes for C1orf198 Gene

genes like me logo Genes that share phenotypes with C1orf198: view

Animal Model Products

CRISPR Products

miRNA for C1orf198 Gene

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C1orf198

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , Transcription Factor Targets and HOMER Transcription for C1orf198 Gene

Localization for C1orf198 Gene

Subcellular locations from UniProtKB/Swiss-Prot for C1orf198 Gene


Subcellular locations from

Jensen Localization Image for C1orf198 Gene COMPARTMENTS Subcellular localization image for C1orf198 gene
Compartment Confidence
cytosol 3

Gene Ontology (GO) - Cellular Components for C1orf198 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005737 cytoplasm IDA --
genes like me logo Genes that share ontologies with C1orf198: view

Pathways & Interactions for C1orf198 Gene

SuperPathways for C1orf198 Gene

No Data Available

Interacting Proteins for C1orf198 Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
Selected Interacting proteins: ENSP00000355623 for C1orf198 Gene via STRING

Gene Ontology (GO) - Biological Process for C1orf198 Gene


No data available for Pathways by source and SIGNOR curated interactions for C1orf198 Gene

Drugs & Compounds for C1orf198 Gene

No Compound Related Data Available

Transcripts for C1orf198 Gene

Unigene Clusters for C1orf198 Gene

Chromosome 1 open reading frame 198:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C1orf198

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C1orf198 Gene

ExUns: 1a · 1b ^ 2 ^ 3a · 3b · 3c ^ 4a · 4b · 4c ^ 5a · 5b ^ 6 ^ 7a · 7b · 7c · 7d · 7e ^ 8
SP1: - - - - - -
SP2: - - - - - - - - -
SP3: - - - - -
SP4: - -
SP7: -

Relevant External Links for C1orf198 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C1orf198 Gene

mRNA expression in normal human tissues for C1orf198 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for C1orf198 Gene

This gene is overexpressed in Bone marrow stromal cell (25.3), Adrenal (7.9), Peripheral blood mononuclear cells (7.8), and Gallbladder (7.1).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for C1orf198 Gene

SOURCE GeneReport for Unigene cluster for C1orf198 Gene Hs.520494

genes like me logo Genes that share expression patterns with C1orf198: view

Primer Products

In Situ Assay Products

No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for C1orf198 Gene

Orthologs for C1orf198 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C1orf198 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia C28H1orf198 35
  • 85.15 (n)
  • 82.69 (a)
C1orf198 36
  • 71 (a)
(Canis familiaris)
Mammalia C4H1orf198 35
  • 86.97 (n)
  • 84.62 (a)
C1orf198 36
  • 81 (a)
(Mus musculus)
Mammalia 2310022B05Rik 35
  • 80.35 (n)
  • 78.83 (a)
2310022B05Rik 16
2310022B05Rik 36
  • 80 (a)
(Rattus norvegicus)
Mammalia RGD1559896 35
  • 79.63 (n)
  • 78.43 (a)
(Monodelphis domestica)
Mammalia C1orf198 36
  • 63 (a)
(Pan troglodytes)
Mammalia C1orf198 36
  • 97 (a)
(Gallus gallus)
Aves C1orf198 36
  • 52 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100485462 35
  • 59.91 (n)
  • 51.13 (a)
(Danio rerio)
Actinopterygii wu:fa18f11 35
  • 57.13 (n)
  • 50.72 (a)
C20H1orf198 36
  • 41 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 22 (a)
Species with no ortholog for C1orf198:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C1orf198 Gene

Gene Tree for C1orf198 (if available)
Gene Tree for C1orf198 (if available)

Paralogs for C1orf198 Gene

No data available for Paralogs for C1orf198 Gene

Variants for C1orf198 Gene

Sequence variations from dbSNP and Humsavar for C1orf198 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs12699 -- 230,837,661(+) ACACA(G/T)GAGCC utr-variant-3-prime
rs748080 -- 230,850,205(+) CTAAC(A/G)GTAAC intron-variant
rs1010189 -- 230,838,515(+) CATTT(A/T)AAAAA utr-variant-3-prime
rs1010958 -- 230,841,227(-) CCTCT(C/T)GTTTC intron-variant
rs1046589 -- 230,837,281(-) CCCGT(C/T)TGAGC utr-variant-3-prime

Variation tolerance for C1orf198 Gene

Residual Variation Intolerance Score: 68.92% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.00; 20.51% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C1orf198 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for C1orf198 Gene

Disorders for C1orf198 Gene

Relevant External Links for C1orf198

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with C1orf198: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C1orf198 Gene

Publications for C1orf198 Gene

  1. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 67
  2. An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. (PMID: 24275569) Bian Y. … Zou H. (J. Proteomics 2014) 67
  3. Systematic validation of antibody binding and protein subcellular localization using siRNA and confocal microscopy. (PMID: 22361696) Stadler C. … Lundberg E. (J. Proteomics 2012) 67
  4. N-terminal acetylome analyses and functional insights of the N- terminal acetyltransferase NatB. (PMID: 22814378) Van Damme P. … Aldabe R. (Proc. Natl. Acad. Sci. U.S.A. 2012) 67
  5. Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PMID: 19690332) Mayya V. … Han D.K. (Sci. Signal. 2009) 67

Products for C1orf198 Gene

Sources for C1orf198 Gene

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