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Aliases for C1orf194 Gene

Aliases for C1orf194 Gene

  • Chromosome 1 Open Reading Frame 194 2 3 5

External Ids for C1orf194 Gene

Previous GeneCards Identifiers for C1orf194 Gene

  • GC01M109450
  • GC01M109648
  • GC01M107541

Summaries for C1orf194 Gene

GeneCards Summary for C1orf194 Gene

C1orf194 (Chromosome 1 Open Reading Frame 194) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C1orf194 Gene

Genomics for C1orf194 Gene

Regulatory Elements for C1orf194 Gene

Enhancers for C1orf194 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01F109088 1.2 ENCODE 33.9 +22.8 22789 4.6 CREB3L1 MLX FEZF1 DMAP1 YY1 SLC30A9 ZNF143 SP3 NFYC TBX21 C1orf194 ENSG00000258634 RPL17P7 RPS27P6 GNAI3 PRPF38B GSTM2 RANP5 WDR47 TMEM167B
GH01F109257 1.1 FANTOM5 ENCODE 34.7 -143.8 -143776 1.3 BCOR KLF1 ZIC2 ZNF121 ZFHX2 GLIS2 PATZ1 FOS CREM EGR2 C1orf194 AKNAD1 CELSR2 PSRC1 PIR46363
GH01F109112 1.1 ENCODE 34.3 +0.3 301 2.5 HDGF PKNOX1 CREB3L1 ARID4B SIN3A ZNF2 YY1 ZNF143 KLF13 ZNF263 C1orf194 RPL17P7 GSTM2 ENSG00000258634 KIAA1324 LOC100420092
GH01F109094 0.8 ENCODE 20.8 +19.1 19132 0.9 PKNOX1 KLF17 BACH1 ZNF2 FOSL1 ZFHX2 ZBTB48 ZNF366 SCRT2 PRDM10 C1orf194 NDUFB3P1 GC01P109115
GH01F109079 1.2 Ensembl ENCODE 13.5 +33.6 33636 1.4 HDAC1 HDGF TBP PKNOX1 CBX3 ARNT NFRKB DMAP1 ZNF48 POLR3A C1orf194 TAF13 TMEM167B
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around C1orf194 on UCSC Golden Path with GeneCards custom track

Promoters for C1orf194 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00001748301 -130 401 ATF1 PKNOX1 CREB3L1 SIN3A BMI1 ZNF48 RCOR1 EGR2 ZNF263 ZBTB11
ENSR00001748300 670 801 HDGF PKNOX1 CREB3L1 ARID4B SIN3A ZNF2 YY1 ZNF143 KLF13 ZNF263

Genomic Location for C1orf194 Gene

Chromosome:
1
Start:
109,105,951 bp from pter
End:
109,113,870 bp from pter
Size:
7,920 bases
Orientation:
Minus strand

Genomic View for C1orf194 Gene

Genes around C1orf194 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C1orf194 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C1orf194 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C1orf194 Gene

Proteins for C1orf194 Gene

  • Protein details for C1orf194 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5T5A4-CA194_HUMAN
    Recommended name:
    Uncharacterized protein C1orf194
    Protein Accession:
    Q5T5A4
    Secondary Accessions:
    • Q5T5A3

    Protein attributes for C1orf194 Gene

    Size:
    169 amino acids
    Molecular mass:
    19350 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for C1orf194 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for C1orf194 Gene

Post-translational modifications for C1orf194 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for C1orf194 Gene

Domains & Families for C1orf194 Gene

Protein Domains for C1orf194 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for C1orf194 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C1orf194: view

No data available for Gene Families and UniProtKB/Swiss-Prot for C1orf194 Gene

Function for C1orf194 Gene

Animal Model Products

Inhibitory RNA Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for C1orf194 Gene

Localization for C1orf194 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C1orf194 gene
Compartment Confidence
nucleus 4
cytosol 2
mitochondrion 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C1orf194 Gene

Pathways & Interactions for C1orf194 Gene

SuperPathways for C1orf194 Gene

No Data Available

Interacting Proteins for C1orf194 Gene

Gene Ontology (GO) - Biological Process for C1orf194 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C1orf194 Gene

Transcripts for C1orf194 Gene

Unigene Clusters for C1orf194 Gene

Chromosome 1 open reading frame 194:
Representative Sequences:

Inhibitory RNA Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C1orf194 Gene

ExUns: 1a · 1b ^ 2a · 2b · 2c ^ 3 ^ 4 ^ 5 ^ 6
SP1: - - -
SP2:
SP3: -
SP4: - - - - -
SP5: - -

Relevant External Links for C1orf194 Gene

GeneLoc Exon Structure for
C1orf194
ECgene alternative splicing isoforms for
C1orf194

Expression for C1orf194 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for C1orf194 Gene

mRNA differential expression in normal tissues according to GTEx for C1orf194 Gene

This gene is overexpressed in Testis (x26.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C1orf194 Gene



NURSA nuclear receptor signaling pathways regulating expression of C1orf194 Gene:

C1orf194

SOURCE GeneReport for Unigene cluster for C1orf194 Gene:

Hs.446962
genes like me logo Genes that share expression patterns with C1orf194: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for C1orf194 Gene

Orthologs for C1orf194 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C1orf194 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C1H1orf194 34
  • 92.78 (n)
C1orf194 35
  • 85 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C6H1orf194 34
  • 84.08 (n)
C1orf194 35
  • 73 (a)
OneToOne
mouse
(Mus musculus)
Mammalia 1700013F07Rik 34 16 35
  • 81.96 (n)
cow
(Bos Taurus)
Mammalia C3H1orf194 34
  • 81.95 (n)
C1orf194 35
  • 71 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia RGD1309139 34
  • 79.59 (n)
platypus
(Ornithorhynchus anatinus)
Mammalia C1orf194 35
  • 66 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia C1orf194 35
  • 57 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia C1orf194 35
  • 43 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100487688 34
  • 50.93 (n)
zebrafish
(Danio rerio)
Actinopterygii si:ch211-163l21.7 34
  • 53.99 (n)
C8H1orf194 35
  • 39 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea -- 35
  • 35 (a)
OneToOne
Species where no ortholog for C1orf194 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C1orf194 Gene

ENSEMBL:
Gene Tree for C1orf194 (if available)
TreeFam:
Gene Tree for C1orf194 (if available)

Paralogs for C1orf194 Gene

No data available for Paralogs for C1orf194 Gene

Variants for C1orf194 Gene

Sequence variations from dbSNP and Humsavar for C1orf194 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs1046921 -- 109,106,597(-) CCTGG(C/G)TAACA reference, synonymous-codon, missense
rs1046923 -- 109,106,589(-) ACATC(A/G)GACAC reference, missense, utr-variant-3-prime
rs111236143 -- 109,107,920(+) AGGTA(A/C/G/T)CTCGG intron-variant, splice-donor-variant
rs111469152 -- 109,114,614(+) AACTC(A/C)GAATG intron-variant, upstream-variant-2KB
rs111598268 -- 109,113,015(+) GAAGT(A/C)CTGAA intron-variant, upstream-variant-2KB, utr-variant-5-prime

Structural Variations from Database of Genomic Variants (DGV) for C1orf194 Gene

Variant ID Type Subtype PubMed ID
esv3894001 CNV gain 25118596
nsv1008458 CNV gain 25217958
nsv831026 CNV loss 17160897
nsv930465 CNV insertion 23359205

Variation tolerance for C1orf194 Gene

Residual Variation Intolerance Score: 84.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.36; 63.37% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C1orf194 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
C1orf194

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C1orf194 Gene

Disorders for C1orf194 Gene

Relevant External Links for C1orf194

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C1orf194

No disorders were found for C1orf194 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C1orf194 Gene

Publications for C1orf194 Gene

  1. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 4 64
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64
  3. Creation of genome-wide protein expression libraries using random activation of gene expression. (PMID: 11329013) Harrington J.J. … Ducar M. (Nat. Biotechnol. 2001) 3 64
  4. Normalization and subtraction: two approaches to facilitate gene discovery. (PMID: 8889548) Bonaldo M.F. … Soares M.B. (Genome Res. 1996) 4 64

Products for C1orf194 Gene

Sources for C1orf194 Gene

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