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Aliases for C1orf194 Gene

Aliases for C1orf194 Gene

  • Chromosome 1 Open Reading Frame 194 2 3 5

External Ids for C1orf194 Gene

Previous GeneCards Identifiers for C1orf194 Gene

  • GC01M109450
  • GC01M109648
  • GC01M107541

Summaries for C1orf194 Gene

GeneCards Summary for C1orf194 Gene

C1orf194 (Chromosome 1 Open Reading Frame 194) is a Protein Coding gene.

Additional gene information for C1orf194 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C1orf194 Gene

Genomics for C1orf194 Gene

Regulatory Elements for C1orf194 Gene

Enhancers for C1orf194 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01H109257 1.4 FANTOM5 ENCODE dbSUPER 34.7 -143.8 -143776 1 BCOR KLF1 ZIC2 ZKSCAN1 ZNF121 ZFHX2 GLIS2 PATZ1 FOS ATF7 C1orf194 AKNAD1 CELSR2 PSRC1 PIR46363
GH01H109088 1.4 ENCODE dbSUPER 33.9 +22.8 22789 4 MLX FEZF1 DMAP1 YY1 SLC30A9 ZNF143 SP3 NFYC ZC3H11A SSRP1 C1orf194 ENSG00000258634 GNAI3 STRIP1 RPL17P7 PRPF38B RPS27P6 RANP5 WDR47 TMEM167B
GH01H109112 1 ENCODE 34.3 +0.3 301 2 PKNOX1 ATF1 ARID4B SIN3A ZNF2 ZNF766 GATA2 ZNF207 ZNF143 ATF7 C1orf194 CLCC1 RPL17P7 GSTM2 KIAA1324 LOC100420092
GH01H109079 1.4 Ensembl ENCODE dbSUPER 13.5 +33.6 33636 1 TBP HDGF PKNOX1 ARNT NFRKB DMAP1 EGR1 POLR3A ATF7 SMARCA5 C1orf194 ENSG00000258634 CLCC1 STRIP1 ATXN7L2 TAF13 TMEM167B
GH01H109099 1.4 ENCODE dbSUPER 12.6 +13.4 13399 1 MLX ZFP64 DMAP1 YY1 SLC30A9 ZNF143 SP3 MEF2D SSRP1 ZNF610 ENSG00000258634 STRIP1 PRPF38B RPL17P7 GNAI3 ENSG00000232971 SLC25A24P2 ENSG00000238122 ENSG00000235005 C1orf194
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around C1orf194 on UCSC Golden Path with GeneCards custom track

Promoters for C1orf194 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000011029 970 201 ATF1 ARID4B SIN3A ZNF2 ZNF766 ZNF207 ZNF143 ATF7 RUNX3 REST

Genomic Location for C1orf194 Gene

Chromosome:
1
Start:
109,105,951 bp from pter
End:
109,113,870 bp from pter
Size:
7,920 bases
Orientation:
Minus strand

Genomic View for C1orf194 Gene

Genes around C1orf194 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C1orf194 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C1orf194 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C1orf194 Gene

Proteins for C1orf194 Gene

  • Protein details for C1orf194 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5T5A4-CA194_HUMAN
    Recommended name:
    Uncharacterized protein C1orf194
    Protein Accession:
    Q5T5A4
    Secondary Accessions:
    • Q5T5A3

    Protein attributes for C1orf194 Gene

    Size:
    169 amino acids
    Molecular mass:
    19350 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for C1orf194 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for C1orf194 Gene

Post-translational modifications for C1orf194 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for C1orf194 Gene

Domains & Families for C1orf194 Gene

Gene Families for C1orf194 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for C1orf194 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for C1orf194 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C1orf194: view

No data available for UniProtKB/Swiss-Prot for C1orf194 Gene

Function for C1orf194 Gene

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for C1orf194
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for C1orf194 Gene

Localization for C1orf194 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C1orf194 gene
Compartment Confidence
nucleus 4
cytosol 2
mitochondrion 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Cytosol (1)
  • Nuclear speckles (1)
See all subcellular structures

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C1orf194 Gene

Pathways & Interactions for C1orf194 Gene

SuperPathways for C1orf194 Gene

No Data Available

Interacting Proteins for C1orf194 Gene

Gene Ontology (GO) - Biological Process for C1orf194 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C1orf194 Gene

Drugs & Compounds for C1orf194 Gene

No Compound Related Data Available

Transcripts for C1orf194 Gene

Unigene Clusters for C1orf194 Gene

Chromosome 1 open reading frame 194:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for C1orf194
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for C1orf194 Gene

ExUns: 1a · 1b ^ 2a · 2b · 2c ^ 3 ^ 4 ^ 5 ^ 6
SP1: - - -
SP2:
SP3: -
SP4: - - - - -
SP5: - -

Relevant External Links for C1orf194 Gene

GeneLoc Exon Structure for
C1orf194
ECgene alternative splicing isoforms for
C1orf194

Expression for C1orf194 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for C1orf194 Gene

mRNA differential expression in normal tissues according to GTEx for C1orf194 Gene

This gene is overexpressed in Testis (x26.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C1orf194 Gene



NURSA nuclear receptor signaling pathways regulating expression of C1orf194 Gene:

C1orf194

SOURCE GeneReport for Unigene cluster for C1orf194 Gene:

Hs.446962
genes like me logo Genes that share expression patterns with C1orf194: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for C1orf194 Gene

Orthologs for C1orf194 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C1orf194 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C1H1orf194 33
  • 92.78 (n)
C1orf194 34
  • 85 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C6H1orf194 33
  • 84.08 (n)
C1orf194 34
  • 73 (a)
OneToOne
mouse
(Mus musculus)
Mammalia 1700013F07Rik 33 16 34
  • 81.96 (n)
cow
(Bos Taurus)
Mammalia C3H1orf194 33
  • 81.95 (n)
C1orf194 34
  • 71 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia RGD1309139 33
  • 79.59 (n)
platypus
(Ornithorhynchus anatinus)
Mammalia C1orf194 34
  • 66 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia C1orf194 34
  • 57 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia C1orf194 34
  • 43 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100487688 33
  • 50.93 (n)
zebrafish
(Danio rerio)
Actinopterygii si:ch211-163l21.7 33
  • 53.99 (n)
C8H1orf194 34
  • 39 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea -- 34
  • 35 (a)
OneToOne
Species where no ortholog for C1orf194 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C1orf194 Gene

ENSEMBL:
Gene Tree for C1orf194 (if available)
TreeFam:
Gene Tree for C1orf194 (if available)

Paralogs for C1orf194 Gene

No data available for Paralogs for C1orf194 Gene

Variants for C1orf194 Gene

Sequence variations from dbSNP and Humsavar for C1orf194 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs1000298997 -- 109,105,868(+) CAGAG(C/T)GAGAC intron-variant, downstream-variant-500B
rs1000704087 -- 109,115,653(+) CTTAT(-/A)AAGAT intron-variant, upstream-variant-2KB
rs1000957356 -- 109,114,064(+) GAAGC(C/G)AGCCT upstream-variant-2KB, utr-variant-5-prime
rs1001108653 -- 109,113,684(+) TTCTT(A/T)CTCTC upstream-variant-2KB, utr-variant-5-prime
rs1001218149 -- 109,112,685(+) GGCTA(A/G)ATGCC intron-variant, upstream-variant-2KB, reference, synonymous-codon

Structural Variations from Database of Genomic Variants (DGV) for C1orf194 Gene

Variant ID Type Subtype PubMed ID
esv3894001 CNV gain 25118596
nsv1008458 CNV gain 25217958
nsv831026 CNV loss 17160897
nsv930465 CNV insertion 23359205

Variation tolerance for C1orf194 Gene

Residual Variation Intolerance Score: 84.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.36; 63.37% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C1orf194 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
C1orf194

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C1orf194 Gene

Disorders for C1orf194 Gene

Relevant External Links for C1orf194

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C1orf194

No disorders were found for C1orf194 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C1orf194 Gene

Publications for C1orf194 Gene

  1. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory SG … Prigmore E (Nature 2006) 4 60
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 60
  3. Creation of genome-wide protein expression libraries using random activation of gene expression. (PMID: 11329013) Harrington JJ … Ducar M (Nature biotechnology 2001) 3 60
  4. Normalization and subtraction: two approaches to facilitate gene discovery. (PMID: 8889548) Bonaldo MF … Soares MB (Genome research 1996) 4 60

Products for C1orf194 Gene

Sources for C1orf194 Gene

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