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Aliases for C1orf189 Gene

Aliases for C1orf189 Gene

  • Chromosome 1 Open Reading Frame 189 2 3

External Ids for C1orf189 Gene

Previous GeneCards Identifiers for C1orf189 Gene

  • GC01M150985
  • GC01M152438
  • GC01M154171
  • GC01M125535

Summaries for C1orf189 Gene

GeneCards Summary for C1orf189 Gene

C1orf189 (Chromosome 1 Open Reading Frame 189) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C1orf189 Gene

Genomics for C1orf189 Gene

Regulatory Elements for C1orf189 Gene

Genomic Location for C1orf189 Gene

154,199,085 bp from pter
154,206,365 bp from pter
7,281 bases
Minus strand

Genomic View for C1orf189 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
GeneLoc Logo Gene Density

RefSeq DNA sequence for C1orf189 Gene

Proteins for C1orf189 Gene

  • Protein details for C1orf189 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized protein C1orf189
    Protein Accession:
    Secondary Accessions:
    • A1L4E3

    Protein attributes for C1orf189 Gene

    101 amino acids
    Molecular mass:
    12131 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C1orf189 Gene

Proteomics data for C1orf189 Gene at MOPED

Post-translational modifications for C1orf189 Gene

No Post-translational modifications

Other Protein References for C1orf189 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C1orf189 Gene

Domains & Families for C1orf189 Gene

Protein Domains for C1orf189 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C1orf189: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C1orf189 Gene

Function for C1orf189 Gene

Gene Ontology (GO) - Molecular Function for C1orf189 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with C1orf189: view

Phenotypes for C1orf189 Gene

GenomeRNAi human phenotypes for C1orf189:
genes like me logo Genes that share phenotypes with C1orf189: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C1orf189

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targets and HOMER Transcription for C1orf189 Gene

Localization for C1orf189 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for C1orf189 Gene

Pathways & Interactions for C1orf189 Gene

SuperPathways for C1orf189 Gene

No Data Available

Interacting Proteins for C1orf189 Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
Selected Interacting proteins: Q5VU69-CA189_HUMAN ENSP00000357511 for C1orf189 Gene via UniProtKB STRING

Gene Ontology (GO) - Biological Process for C1orf189 Gene


No data available for Pathways by source and SIGNOR curated interactions for C1orf189 Gene

Drugs & Compounds for C1orf189 Gene

No Compound Related Data Available

Transcripts for C1orf189 Gene

mRNA/cDNA for C1orf189 Gene

(1) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(6) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for C1orf189 Gene

Chromosome 1 open reading frame 189:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C1orf189

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C1orf189 Gene

No ASD Table

Relevant External Links for C1orf189 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C1orf189 Gene

mRNA expression in normal human tissues for C1orf189 Gene

mRNA differential expression in normal tissues according to GTEx for C1orf189 Gene

This gene is overexpressed in Testis (x31.6) and Cervix - Endocervix (x4.7).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for C1orf189 Gene

SOURCE GeneReport for Unigene cluster for C1orf189 Gene Hs.104967

genes like me logo Genes that share expression patterns with C1orf189: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for C1orf189 Gene

Orthologs for C1orf189 Gene

This gene was present in the common ancestor of mammals.

Orthologs for C1orf189 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia C3H1orf189 35
  • 88.45 (n)
  • 83.17 (a)
C3H1orf189 36
  • 83 (a)
(Canis familiaris)
Mammalia C7H1orf189 35
  • 88.45 (n)
  • 81.19 (a)
C1orf189 36
  • 81 (a)
(Mus musculus)
Mammalia 1700094D03Rik 35
  • 83.17 (n)
  • 74.26 (a)
1700094D03Rik 16
1700094D03Rik 36
  • 71 (a)
(Pan troglodytes)
Mammalia C1H1orf189 35
  • 99.67 (n)
  • 99.01 (a)
C1orf189 36
  • 99 (a)
(Rattus norvegicus)
Mammalia RGD1564171 35
  • 83.17 (n)
  • 78.22 (a)
(Monodelphis domestica)
Mammalia C1orf189 36
  • 58 (a)
Species with no ortholog for C1orf189:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C1orf189 Gene

Gene Tree for C1orf189 (if available)
Gene Tree for C1orf189 (if available)

Paralogs for C1orf189 Gene

No data available for Paralogs for C1orf189 Gene

Variants for C1orf189 Gene

Sequence variations from dbSNP and Humsavar for C1orf189 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs4845608 -- 154,199,277(+) GAGAG(G/T)GGAGA utr-variant-3-prime
rs6703024 -- 154,203,519(+) aacct(A/C)ttagg intron-variant
rs11265285 -- 154,202,093(+) CACCA(C/T)GCCCA intron-variant
rs12726220 -- 154,199,074(+) AGCCC(A/G)GTGGT downstream-variant-500B
rs34647909 -- 154,201,788(+) TTTTT(-/T)GAGAA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C1orf189 Gene

Variant ID Type Subtype PubMed ID
nsv2954 CNV Insertion 18451855

Variation tolerance for C1orf189 Gene

Residual Variation Intolerance Score: 65.21% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.08; 22.10% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C1orf189 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C1orf189 Gene

Disorders for C1orf189 Gene

Relevant External Links for C1orf189

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with C1orf189: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C1orf189 Gene

Publications for C1orf189 Gene

  1. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 67
  2. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 67
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 67
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 67

Products for C1orf189 Gene

Sources for C1orf189 Gene

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