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Aliases for C1orf189 Gene

Aliases for C1orf189 Gene

  • Chromosome 1 Open Reading Frame 189 2 3

External Ids for C1orf189 Gene

Summaries for C1orf189 Gene

GeneCards Summary for C1orf189 Gene

C1orf189 (Chromosome 1 Open Reading Frame 189) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C1orf189 Gene

Genomics for C1orf189 Gene

Genomic Location for C1orf189 Gene

Start:
154,199,085 bp from pter
End:
154,206,365 bp from pter
Size:
7,281 bases
Orientation:
Minus strand

Genomic View for C1orf189 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for C1orf189 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C1orf189 Gene

Regulatory Elements for C1orf189 Gene

Proteins for C1orf189 Gene

  • Protein details for C1orf189 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5VU69-CA189_HUMAN
    Recommended name:
    Uncharacterized protein C1orf189
    Protein Accession:
    Q5VU69
    Secondary Accessions:
    • A1L4E3

    Protein attributes for C1orf189 Gene

    Size:
    101 amino acids
    Molecular mass:
    12131 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C1orf189 Gene

Proteomics data for C1orf189 Gene at MOPED

Post-translational modifications for C1orf189 Gene

No Post-translational modifications

Other Protein References for C1orf189 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C1orf189 Gene

Domains for C1orf189 Gene

Protein Domains for C1orf189 Gene

InterPro:
ProtoNet:
genes like me logo Genes that share domains with C1orf189: view

No data available for Gene Families and UniProtKB/Swiss-Prot for C1orf189 Gene

Function for C1orf189 Gene

Gene Ontology (GO) - Molecular Function for C1orf189 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with C1orf189: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for C1orf189 Gene

Localization for C1orf189 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for C1orf189 Gene COMPARTMENTS Subcellular localization image for C1orf189 gene
Compartment Confidence
cytosol 2
nucleus 2
mitochondrion 1

No data available for Gene Ontology (GO) - Cellular Components for C1orf189 Gene

Pathways for C1orf189 Gene

SuperPathways for C1orf189 Gene

No Data Available

Interacting Proteins for C1orf189 Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000357511%0d%0a9606.ENSP00000345341%0d%0a9606.ENSP00000356785%0d%0a
Selected Interacting proteins: ENSP00000357511 Q5VU69-CA189_HUMAN for C1orf189 Gene via STRING UniProtKB

Gene Ontology (GO) - Biological Process for C1orf189 Gene

None

No data available for Pathways by source for C1orf189 Gene

Transcripts for C1orf189 Gene

mRNA/cDNA for C1orf189 Gene

(1) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(6) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for C1orf189 Gene

Chromosome 1 open reading frame 189:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for C1orf189 Gene

No ASD Table

Relevant External Links for C1orf189 Gene

GeneLoc Exon Structure for
C1orf189
ECgene alternative splicing isoforms for
C1orf189

Expression for C1orf189 Gene

mRNA expression in normal human tissues for C1orf189 Gene

mRNA differential expression in normal tissues according to GTEx for C1orf189 Gene

This gene is overexpressed in Testis (31.6) and Cervix - Endocervix (4.7).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for C1orf189 Gene

SOURCE GeneReport for Unigene cluster for C1orf189 Gene Hs.104967

genes like me logo Genes that share expressions with C1orf189: view

Orthologs for C1orf189 Gene

This gene was present in the common ancestor of mammals.

Orthologs for C1orf189 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C1H1orf189 36
  • 99.67 (n)
  • 99.01 (a)
C1orf189 37
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia C3H1orf189 36
  • 88.45 (n)
  • 83.17 (a)
C3H1orf189 37
  • 83 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C1orf189 37
  • 81 (a)
OneToOne
C7H1orf189 36
  • 88.45 (n)
  • 81.19 (a)
mouse
(Mus musculus)
Mammalia 1700094D03Rik 36
  • 83.17 (n)
  • 74.26 (a)
1700094D03Rik 16
1700094D03Rik 37
  • 71 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia C1orf189 37
  • 58 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia RGD1564171 36
  • 83.17 (n)
  • 78.22 (a)
Species with no ortholog for C1orf189:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C1orf189 Gene

ENSEMBL:
Gene Tree for C1orf189 (if available)
TreeFam:
Gene Tree for C1orf189 (if available)

Paralogs for C1orf189 Gene

No data available for Paralogs for C1orf189 Gene

Variants for C1orf189 Gene

Sequence variations from dbSNP and Humsavar for C1orf189 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs4845608 -- 154,199,277(+) GAGAG(G/T)GGAGA utr-variant-3-prime
rs6703024 -- 154,203,519(+) aacct(A/C)ttagg intron-variant
rs11265285 -- 154,202,093(+) CACCA(C/T)GCCCA intron-variant
rs12726220 -- 154,199,074(+) AGCCC(A/G)GTGGT downstream-variant-500B
rs34647909 -- 154,201,788(+) TTTTT(-/T)GAGAA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C1orf189 Gene

Variant ID Type Subtype PubMed ID
nsv2954 CNV Insertion 18451855

Relevant External Links for C1orf189 Gene

HapMap Linkage Disequilibrium report
C1orf189

Disorders for C1orf189 Gene

No disorders were found for C1orf189 Gene.

No data available for UniProtKB/Swiss-Prot for C1orf189 Gene

Publications for C1orf189 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  2. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4
  3. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for C1orf189 Gene

Sources for C1orf189 Gene

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