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Aliases for C1orf185 Gene

Aliases for C1orf185 Gene

  • Chromosome 1 Open Reading Frame 185 2 3

External Ids for C1orf185 Gene

Previous GeneCards Identifiers for C1orf185 Gene

  • GC01P051281
  • GC01P051340
  • GC01P051567
  • GC01P049685

Summaries for C1orf185 Gene

GeneCards Summary for C1orf185 Gene

C1orf185 (Chromosome 1 Open Reading Frame 185) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C1orf185 Gene

Genomics for C1orf185 Gene

Regulatory Elements for C1orf185 Gene

Transcription factor binding sites by QIAGEN in the C1orf185 gene promoter:

Genomic Location for C1orf185 Gene

50,976,457 bp from pter
51,148,086 bp from pter
171,630 bases
Plus strand

Genomic View for C1orf185 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for C1orf185 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C1orf185 Gene

Proteins for C1orf185 Gene

  • Protein details for C1orf185 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized protein C1orf185
    Protein Accession:
    Secondary Accessions:
    • A6NHS3

    Protein attributes for C1orf185 Gene

    199 amino acids
    Molecular mass:
    22411 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C1orf185 Gene

Proteomics data for C1orf185 Gene at MOPED

Post-translational modifications for C1orf185 Gene

No Post-translational modifications

Other Protein References for C1orf185 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C1orf185 Gene

Domains for C1orf185 Gene

Protein Domains for C1orf185 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C1orf185: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C1orf185 Gene

Function for C1orf185 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for C1orf185 Gene

Localization for C1orf185 Gene

Subcellular locations from UniProtKB/Swiss-Prot for C1orf185 Gene

Membrane; Single-pass membrane protein.

Subcellular locations from

Jensen Localization Image for C1orf185 Gene COMPARTMENTS Subcellular localization image for C1orf185 gene
Compartment Confidence
endoplasmic reticulum 1
plasma membrane 1

Gene Ontology (GO) - Cellular Components for C1orf185 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with C1orf185: view

Pathways for C1orf185 Gene

SuperPathways for C1orf185 Gene

No Data Available

Interacting Proteins for C1orf185 Gene

Gene Ontology (GO) - Biological Process for C1orf185 Gene


No data available for Pathways by source for C1orf185 Gene

Transcripts for C1orf185 Gene

mRNA/cDNA for C1orf185 Gene

(2) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(8) Selected AceView cDNA sequences:
(4) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for C1orf185 Gene

Chromosome 1 open reading frame 185:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C1orf185

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C1orf185 Gene

No ASD Table

Relevant External Links for C1orf185 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C1orf185 Gene

mRNA expression in normal human tissues for C1orf185 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for C1orf185 Gene

This gene is overexpressed in Testis (52.3).

SOURCE GeneReport for Unigene cluster for C1orf185 Gene Hs.176177

genes like me logo Genes that share expressions with C1orf185: view

Primer Products

In Situ Assay Products

No data available for Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for C1orf185 Gene

Orthologs for C1orf185 Gene

This gene was present in the common ancestor of mammals.

Orthologs for C1orf185 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia C3H1orf185 35
  • 88.44 (n)
  • 80.4 (a)
C3H1orf185 36
  • 69 (a)
(Canis familiaris)
Mammalia C15H1orf185 35
  • 89.78 (n)
  • 84.42 (a)
C1orf185 36
  • 73 (a)
(Mus musculus)
Mammalia 4930522H14Rik 35
  • 72.59 (n)
  • 57.36 (a)
4930522H14Rik 16
4930522H14Rik 36
  • 49 (a)
(Pan troglodytes)
Mammalia C1H1orf185 35
  • 99.16 (n)
  • 98.49 (a)
C1orf185 36
  • 98 (a)
(Rattus norvegicus)
Mammalia LOC689589 35
  • 75.09 (n)
  • 64.21 (a)
Species with no ortholog for C1orf185:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C1orf185 Gene

Gene Tree for C1orf185 (if available)
Gene Tree for C1orf185 (if available)

Paralogs for C1orf185 Gene

No data available for Paralogs for C1orf185 Gene

Variants for C1orf185 Gene

Sequence variations from dbSNP and Humsavar for C1orf185 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs949504 -- 51,107,439(-) TTTTA(C/G)TATTA intron-variant
rs999138 -- 51,119,884(+) AGCCC(A/G)GCCCT intron-variant
rs1137139 -- 51,010,461(+) GGCCA(A/G)GCTGG intron-variant
rs1341979 -- 50,984,929(-) GCTGG(C/G)AAGAT intron-variant
rs1928898 -- 51,097,801(+) GTGCC(A/G)TTGCA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C1orf185 Gene

Variant ID Type Subtype PubMed ID
esv2671256 CNV Deletion 23128226

Relevant External Links for C1orf185 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C1orf185 Gene

Disorders for C1orf185 Gene

No disorders were found for C1orf185 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for C1orf185 Gene

Publications for C1orf185 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4
  3. Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction. (PMID: 21076409) Sotoodehnia N. … Arking D.E. (Nat. Genet. 2010) 3

Products for C1orf185 Gene

Sources for C1orf185 Gene

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