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Aliases for C1orf185 Gene

Aliases for C1orf185 Gene

  • Chromosome 1 Open Reading Frame 185 2 3 5

External Ids for C1orf185 Gene

Previous GeneCards Identifiers for C1orf185 Gene

  • GC01P051281
  • GC01P051340
  • GC01P051567
  • GC01P049685
  • GC01P050976

Summaries for C1orf185 Gene

GeneCards Summary for C1orf185 Gene

C1orf185 (Chromosome 1 Open Reading Frame 185) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C1orf185 Gene

Genomics for C1orf185 Gene

Regulatory Elements for C1orf185 Gene

Transcription factor binding sites by QIAGEN in the C1orf185 gene promoter:

Genomic Location for C1orf185 Gene

Chromosome:
1
Start:
51,102,234 bp from pter
End:
51,148,086 bp from pter
Size:
45,853 bases
Orientation:
Plus strand

Genomic View for C1orf185 Gene

Genes around C1orf185 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C1orf185 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C1orf185 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C1orf185 Gene

Proteins for C1orf185 Gene

  • Protein details for C1orf185 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5T7R7-CA185_HUMAN
    Recommended name:
    Uncharacterized protein C1orf185
    Protein Accession:
    Q5T7R7
    Secondary Accessions:
    • A6NHS3

    Protein attributes for C1orf185 Gene

    Size:
    199 amino acids
    Molecular mass:
    22411 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C1orf185 Gene

Proteomics data for C1orf185 Gene at MOPED

Post-translational modifications for C1orf185 Gene

No Post-translational modifications

Other Protein References for C1orf185 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C1orf185 Gene

Domains & Families for C1orf185 Gene

Protein Domains for C1orf185 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C1orf185: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C1orf185 Gene

Function for C1orf185 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for C1orf185 Gene

Localization for C1orf185 Gene

Subcellular locations from UniProtKB/Swiss-Prot for C1orf185 Gene

Membrane; Single-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for C1orf185 Gene COMPARTMENTS Subcellular localization image for C1orf185 gene
Compartment Confidence
endoplasmic reticulum 1
plasma membrane 1

No data available for Gene Ontology (GO) - Cellular Components for C1orf185 Gene

Pathways & Interactions for C1orf185 Gene

SuperPathways for C1orf185 Gene

No Data Available

Interacting Proteins for C1orf185 Gene

Gene Ontology (GO) - Biological Process for C1orf185 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C1orf185 Gene

Drugs & Compounds for C1orf185 Gene

No Compound Related Data Available

Transcripts for C1orf185 Gene

mRNA/cDNA for C1orf185 Gene

(2) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(8) Selected AceView cDNA sequences:
(4) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for C1orf185 Gene

Chromosome 1 open reading frame 185:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for C1orf185 Gene

No ASD Table

Relevant External Links for C1orf185 Gene

GeneLoc Exon Structure for
C1orf185
ECgene alternative splicing isoforms for
C1orf185

Expression for C1orf185 Gene

mRNA expression in normal human tissues for C1orf185 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for C1orf185 Gene

This gene is overexpressed in Testis (x52.3).

SOURCE GeneReport for Unigene cluster for C1orf185 Gene Hs.176177

genes like me logo Genes that share expression patterns with C1orf185: view

Primer Products

In Situ Assay Products

No data available for Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for C1orf185 Gene

Orthologs for C1orf185 Gene

This gene was present in the common ancestor of mammals.

Orthologs for C1orf185 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C1H1orf185 35
  • 99.16 (n)
  • 98.49 (a)
C1orf185 36
  • 98 (a)
OneToOne
cow
(Bos Taurus)
Mammalia C3H1orf185 36
  • 69 (a)
OneToOne
C3H1orf185 35
  • 88.44 (n)
  • 80.4 (a)
dog
(Canis familiaris)
Mammalia C15H1orf185 35
  • 89.78 (n)
  • 84.42 (a)
C1orf185 36
  • 73 (a)
OneToOne
mouse
(Mus musculus)
Mammalia 4930522H14Rik 36
  • 49 (a)
OneToOne
4930522H14Rik 16
4930522H14Rik 35
  • 72.59 (n)
  • 57.36 (a)
rat
(Rattus norvegicus)
Mammalia LOC689589 35
  • 75.09 (n)
  • 64.21 (a)
Species with no ortholog for C1orf185:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C1orf185 Gene

ENSEMBL:
Gene Tree for C1orf185 (if available)
TreeFam:
Gene Tree for C1orf185 (if available)

Paralogs for C1orf185 Gene

No data available for Paralogs for C1orf185 Gene

Variants for C1orf185 Gene

Sequence variations from dbSNP and Humsavar for C1orf185 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs999138 -- 51,119,884(+) AGCCC(A/G)GCCCT intron-variant
rs2026813 -- 51,111,374(+) TCTTT(C/T)TTTTT intron-variant
rs2026814 -- 51,118,410(+) TTAGC(C/T)CTGCA intron-variant
rs2897090 -- 51,112,323(+) GCATG(A/G)GACTA intron-variant
rs4926879 -- 51,104,374(+) TAATA(C/T)ATAGG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C1orf185 Gene

Variant ID Type Subtype PubMed ID
esv2671256 CNV Deletion 23128226

Variation tolerance for C1orf185 Gene

Gene Damage Index Score: 1.46; 28.59% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C1orf185 Gene

HapMap Linkage Disequilibrium report
C1orf185

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C1orf185 Gene

Disorders for C1orf185 Gene

Relevant External Links for C1orf185

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C1orf185

No disorders were found for C1orf185 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C1orf185 Gene

Publications for C1orf185 Gene

  1. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4 67
  2. Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction. (PMID: 21076409) Sotoodehnia N. … Arking D.E. (Nat. Genet. 2010) 3
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3

Products for C1orf185 Gene

Sources for C1orf185 Gene

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