C1orf168 Gene
protein-coding GIFtS: 39
GCID: GC01M057184
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|
chromosome 1 open reading frame 168
| |
Aliases
for C1orf168 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Chromosome 1 Open Reading Frame 1681 2 | | FLJ432081 | | RP4-758N20.21 | | Uncharacterized Protein C1orf1682 |
Export aliases for C1orf168 gene to outside databasesPrevious GC identifers: GC01M056897 GC01M055296 |
Summaries
for C1orf168 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for C1orf168 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000001.10 NC_018912.1 NT_032977.9
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the C1orf168 gene promoter:
SRF SRF (504 AA) IRF-1 IRF-2 PPAR-gamma1 POU2F1 POU2F1a PPAR-gamma2
Other transcription factors
Search SABiosciences Chromatin IP Primers for C1orf168
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C1orf168 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 1p32.2 Ensembl cytogenetic band: 1p32.2 HGNC cytogenetic band: 1p32.2C1orf168 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01M057184: view genomic region
(about GC identifiers)
Start:
|
57,184,477 bp from pter |
End:
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57,285,369 bp from pter |
Size:
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100,893 bases |
Orientation:
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minus strand |
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Proteins
for C1orf168 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CA168_HUMAN, Q5VWT5 (See
protein sequence)Recommended Name: Uncharacterized protein C1orf168 Size: 728 amino acids; 82070 Da
Secondary accessions: Q63HM3 Q6ZUY6Alternative splicing: 2 isoforms: Q5VWT5-1 Q5VWT5-2 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for C1orf168: NX_Q5VWT5
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q5VWT5
C1orf168 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_001004303.3
ENSEMBL proteins: ENSP00000345972
Human Recombinant Protein Products:
C1orf168 Antibody Products:
Assay Products for C1orf168: |
Protein
Domains /
Families
for C1orf168 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
C1orf168 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q5VWT5ProtoNet protein and cluster: Q5VWT5 |
Function
for C1orf168 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C1orf168 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C1orf168
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
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In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C1orf168 |
|
Pathways & Interactions
for C1orf168 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for C1orf168
STRING Interaction
Network Preview (showing 1 interactants - click image to see more details)
1 Interacting protein for C1orf168 (Q5VWT53 ENSP000003459724) via UniProtKB, MINT, STRING, and/or I2DAbout this table
|
Drugs & Compounds
for C1orf168 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for C1orf168
Search CenterWatch for drugs/clinical trials and news about C1orf168 / CA168
|
Transcripts
for C1orf168 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for C1orf168 gene: NM_001004303.4 Unigene Cluster for C1orf168: Chromosome 1 open reading frame 168 Hs.437655 [show with all ESTs]Unigene Representative Sequence: NM_0010043035 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000343433(uc001cym.4) ENST00000493000(uc001cyl.3) ENST00000497991
ENST00000484327(uc009vzu.1 uc009vzv.1) ENST00000371240
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C1orf168 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C1orf168
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: C1orf168 (NM_001004303) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for C1orf168 | | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat C1orf168 |
Additional cDNA sequence: AK093468.1 AK125198.1 AK310842.1 BX648439.1 6 DOTS entries: DT.101972848 DT.101966421 DT.104943 DT.100742147 DT.121434448 DT.426745 24/48 AceView cDNA sequences (see all 48): AX748145 AI475949 AI553712 AI792637 AK125198 AI076431 AI824534 AK093468 AA676740 NM_001004303 CA396100 AI078379 AI261464 BG190830 BX108433 AA678172 AI733816 BG567993 BX648439 AI452457 AA702373 AV718552 AV658587 AA700076
GeneLoc Exon Structure
2 Alternative Splicing Database (ASD) splice patterns (SP) for C1orf168 About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15a | · | 15b |
|---|
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| SP1: | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | - | | | | - | | | | - | | | | | |
ECgene alternative splicing isoforms for C1orf168
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Expression
for C1orf168 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| C1orf168 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TCAAAATTTT
About this image
See C1orf168 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for C1orf168
SOURCE GeneReport for Unigene cluster: Hs.437655
SABiosciences Custom PCR Arrays for C1orf168
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C1orf168
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat C1orf168 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C1orf168 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C1orf168 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C1orf168 |
Orthologs
for C1orf168 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for C1orf168 gene from 3/7 species (see all 7) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
C8H1orf1681 |
chromosome 8 open reading frame, human C1orf168 |
48.41(n)
31.88(a) |
|
424668 XM_422501.3 XP_422501.2 |
lizard
(Anolis carolinensis) |
Reptilia |
C1orf1686 |
-- |
46(a) |
1 ↔ 1 |
4(103269541-103284723) |
zebrafish
(Danio rerio) |
Actinopterygii |
si:dkeyp-118g6.46si:ch211-147j13.36 |
si:ch211-147j13.3 |
27(a)16(a) |
many ↔ manymany ↔ many |
5(9094420-9106454) 21(18672070-18694226) |
ENSEMBL Gene Tree for C1orf168 (if available)
TreeFam Gene Tree for C1orf168 (if available) |
Paralogs
for C1orf168 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for C1orf168 gene
- PRAM12 FYB2
C1orf168 for paralogs About GeneDecksing
|
Genomic Variants
for C1orf168 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 1 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for C1orf168 (57184477 - 57285369 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 8 variations for C1orf168
1 CNV: 97364
7 Indels: 39605 44594 60825 24230 11395 42432 39606 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing C1orf168 |
|
Disorders
/ Diseases
for C1orf168 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for C1orf168 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for C1orf168 gene integrated from 9 sources:
(articles sorted by number of sources associating them with C1orf168) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2, 3 Ota T.... Sugano S. (2004)
- Genome-wide association analysis identifies TYW3/CRYZ and NDST4 loci associated with circulating resistin levels. (PubMed id 22843503)1 Qi Q....Qi L. (2012)
- The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
- The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)2 Gregory S.G.... Bentley D.R. (2006)
- Normalization and subtraction: two approaches to facilitate gene discovery. (PubMed id 8889548)1 Bonaldo M.F.... Soares M.B. (1996)
|
External Searches for C1orf168 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing C1orf168 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing C1orf168 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing C1orf168 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for C1orf168 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for C1orf168 gene:
Search GeneIP for patents involving C1orf168
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for C1orf168 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for C1orf168 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for C1orf168 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C1orf168 | | | OriGene Protein Over-expression Lysate for C1orf168 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for C1orf168 | | OriGene 3'-UTR Clone for C1orf168 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C1orf168 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C1orf168 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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 | | | C1orf168 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C1orf168 |
|  |  |  | | | | Search ThermoFisher Antibodies for C1orf168 |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat C1orf168 |
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