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Aliases for C1orf167 Gene

Aliases for C1orf167 Gene

  • Chromosome 1 Open Reading Frame 167 2 3 5

External Ids for C1orf167 Gene

Previous GeneCards Identifiers for C1orf167 Gene

  • GC01P011757
  • GC01P011744
  • GC01P011755
  • GC01P011821
  • GC01P010981

Summaries for C1orf167 Gene

GeneCards Summary for C1orf167 Gene

C1orf167 (Chromosome 1 Open Reading Frame 167) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C1orf167 Gene

Genomics for C1orf167 Gene

Regulatory Elements for C1orf167 Gene

Enhancers for C1orf167 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01F011879 1.9 VISTA FANTOM5 Ensembl ENCODE 10.2 +120.2 120224 4.1 HDGF PKNOX1 ZFP64 ARID4B YY1 KLF13 SP5 REST MEF2D SMARCA4 PLOD1 KIAA2013 NPPB RNU5E-1 RNU5E-4P NPPA-AS1 LOC102724659 C1orf167 LOC390997 ENSG00000226849
GH01F011707 1.2 Ensembl ENCODE 11.3 -54.0 -54031 0.9 HDGF FEZF1 GLIS2 POLR3A SCRT2 ZNF548 ZNF263 USF2 CEBPB ZEB2 EXOSC10 AGTRAP ENSG00000226849 MTOR FBXO2 FBXO44 C1orf167 LOC102724659 MTHFR ENSG00000271895
GH01F011813 0.6 Ensembl 11.9 +51.5 51514 0.2 RFX1 NR2F1 ZNF384 PRDM10 NR2F6 RARA LOC102724659 C1orf167 NPPB RNU5E-1 RNU5E-4P PLOD1 KIAA2013 MTHFR NPPA-AS1
GH01F011704 0.5 ENCODE 11.3 -57.4 -57359 0.1 PKNOX1 PBX2 ZBTB20 AGTRAP FBXO2 FBXO44 C1orf167 LOC102724659 C1orf127 MAD2L2 GC01P011722
GH01F011703 0.5 Ensembl 11.3 -57.9 -57887 0.2 ZFHX2 ZNF600 EBF1 EGR2 AGTRAP FBXO2 FBXO44 C1orf167 LOC102724659 C1orf127 MAD2L2 GC01P011722
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around C1orf167 on UCSC Golden Path with GeneCards custom track

Genomic Location for C1orf167 Gene

11,761,787 bp from pter
11,789,585 bp from pter
27,799 bases
Plus strand

Genomic View for C1orf167 Gene

Genes around C1orf167 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C1orf167 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C1orf167 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C1orf167 Gene

Proteins for C1orf167 Gene

  • Protein details for C1orf167 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized protein C1orf167
    Protein Accession:
    Secondary Accessions:
    • Q8NDA9
    • Q8NDF3

    Protein attributes for C1orf167 Gene

    1468 amino acids
    Molecular mass:
    162423 Da
    Quaternary structure:
    No Data Available
    • Sequence=CAI15881.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

    Alternative splice isoforms for C1orf167 Gene


neXtProt entry for C1orf167 Gene

Post-translational modifications for C1orf167 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for C1orf167 Gene

Domains & Families for C1orf167 Gene

Protein Domains for C1orf167 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C1orf167: view

No data available for Gene Families and UniProtKB/Swiss-Prot for C1orf167 Gene

Function for C1orf167 Gene

genes like me logo Genes that share phenotypes with C1orf167: view

Animal Model Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for C1orf167 Gene

Localization for C1orf167 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C1orf167 gene
Compartment Confidence
nucleus 2
mitochondrion 1
cytosol 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C1orf167 Gene

Pathways & Interactions for C1orf167 Gene

SuperPathways for C1orf167 Gene

No Data Available

Interacting Proteins for C1orf167 Gene

Gene Ontology (GO) - Biological Process for C1orf167 Gene


No data available for Pathways by source and SIGNOR curated interactions for C1orf167 Gene

Transcripts for C1orf167 Gene

Unigene Clusters for C1orf167 Gene

Chromosome 1 open reading frame 167:
Representative Sequences:

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C1orf167 Gene

No ASD Table

Relevant External Links for C1orf167 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C1orf167 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for C1orf167 Gene

mRNA differential expression in normal tissues according to GTEx for C1orf167 Gene

This gene is overexpressed in Testis (x50.8).

Protein differential expression in normal tissues from HIPED for C1orf167 Gene

This gene is overexpressed in Esophagus (34.9), Platelet (14.9), and Peripheral blood mononuclear cells (11.6).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for C1orf167 Gene

Protein tissue co-expression partners for C1orf167 Gene

NURSA nuclear receptor signaling pathways regulating expression of C1orf167 Gene:


SOURCE GeneReport for Unigene cluster for C1orf167 Gene:

genes like me logo Genes that share expression patterns with C1orf167: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for C1orf167 Gene

Orthologs for C1orf167 Gene

This gene was present in the common ancestor of mammals.

Orthologs for C1orf167 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia LOC737382 34
  • 98.04 (n)
C1orf167 35
  • 96 (a)
(Bos Taurus)
Mammalia C1orf167 35
  • 54 (a)
(Ornithorhynchus anatinus)
Mammalia C1orf167 35
  • 30 (a)
(Canis familiaris)
Mammalia C1orf167 35
  • 28 (a)
Species where no ortholog for C1orf167 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C1orf167 Gene

Gene Tree for C1orf167 (if available)
Gene Tree for C1orf167 (if available)

Paralogs for C1orf167 Gene

(1) SIMAP similar genes for C1orf167 Gene using alignment to 7 proteins:

genes like me logo Genes that share paralogs with C1orf167: view

No data available for Paralogs for C1orf167 Gene

Variants for C1orf167 Gene

Sequence variations from dbSNP and Humsavar for C1orf167 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs10158409 -- 11,763,216(+) gggcc(A/G)atcac intron-variant, upstream-variant-2KB
rs10218813 -- 11,765,794(+) CTGGA(C/G)AGCTT intron-variant
rs1057624 -- 11,786,213(-) AGGCT(A/G)TCAAC intron-variant, utr-variant-3-prime
rs10779764 -- 11,772,254(+) TGGCT(C/G)TGCAG reference, synonymous-codon
rs10779765 -- 11,777,954(+) TCCCC(C/T)GGGCT intron-variant, nc-transcript-variant

Structural Variations from Database of Genomic Variants (DGV) for C1orf167 Gene

Variant ID Type Subtype PubMed ID
nsv832758 CNV loss 17160897
nsv508880 CNV insertion 20534489

Variation tolerance for C1orf167 Gene

Gene Damage Index Score: 14.54; 96.48% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C1orf167 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C1orf167 Gene

Disorders for C1orf167 Gene

Relevant External Links for C1orf167

Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for C1orf167 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C1orf167 Gene

Publications for C1orf167 Gene

  1. Multiple transcription start sites and alternative splicing in the methylenetetrahydrofolate reductase gene result in two enzyme isoforms. (PMID: 12370778) Tran P. … Rozen R. (Mamm. Genome 2002) 2 3 64
  2. Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease. (PMID: 23824729) van Meurs J.B. … Ahmadi K.R. (Am. J. Clin. Nutr. 2013) 3 64
  3. Identification of type 2 diabetes-associated combination of SNPs using support vector machine. (PMID: 20416077) Ban H.J. … Park K.J. (BMC Genet. 2010) 3 64
  4. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PMID: 20628086) Bailey S.D. … Anand S. (Diabetes Care 2010) 3 64
  5. Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. (PMID: 19913121) Talmud P.J. … . (Am. J. Hum. Genet. 2009) 3 64

Products for C1orf167 Gene

Sources for C1orf167 Gene

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