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Aliases for C1orf162 Gene

Aliases for C1orf162 Gene

  • Chromosome 1 Open Reading Frame 162 2 3 5

External Ids for C1orf162 Gene

Previous GeneCards Identifiers for C1orf162 Gene

  • GC01P111729
  • GC01P111818
  • GC01P112016
  • GC01P109888

Summaries for C1orf162 Gene

GeneCards Summary for C1orf162 Gene

C1orf162 (Chromosome 1 Open Reading Frame 162) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C1orf162 Gene

Genomics for C1orf162 Gene

Regulatory Elements for C1orf162 Gene

Enhancers for C1orf162 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01F111504 1.1 FANTOM5 ENCODE 19.1 +40.4 40436 6.0 HDGF PKNOX1 WRNIP1 SIN3A ARID4B DMAP1 ZNF2 ZNF143 MXD4 REST C1orf162 RAP1A FAM212B ADORA3 DRAM2 CEPT1
GH01F111502 0.5 ENCODE 11.7 +36.4 36364 2.1 HDAC1 GATA2 ETV6 USF2 CEBPB ZEB2 ELF1 ZNF623 CREB3 MEF2D C1orf162 ADORA3 GC01M111493 RNU6-792P
GH01F111627 0.4 ENCODE 10.8 +161.6 161552 2.1 PKNOX1 ARID4B DNMT3B CHAMP1 RARA ZNF766 ZNF143 CREM MIER1 CEBPB UBE2FP3 RNU6-151P KRT18P57 C1orf162 LINC01160
GH01F111441 0.2 ENCODE 10.7 -25.7 -25734 0.2 GATAD2A CTCF ESRRA SMC3 RAD21 C1orf162 DENND2D ENSG00000243960 GC01P111447
GH01F111624 0.6 ENCODE 10.4 +157.0 156970 0.7 TBP MXI1 RAP1A RNU6-151P KRT18P57 ATP5F1 WDR77 C1orf162 UBE2FP3 LINC01160
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around C1orf162 on UCSC Golden Path with GeneCards custom track

Genomic Location for C1orf162 Gene

Chromosome:
1
Start:
111,467,487 bp from pter
End:
111,478,512 bp from pter
Size:
11,026 bases
Orientation:
Plus strand

Genomic View for C1orf162 Gene

Genes around C1orf162 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C1orf162 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C1orf162 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C1orf162 Gene

Proteins for C1orf162 Gene

  • Protein details for C1orf162 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NEQ5-CA162_HUMAN
    Recommended name:
    Transmembrane protein C1orf162
    Protein Accession:
    Q8NEQ5
    Secondary Accessions:
    • Q5QNZ1

    Protein attributes for C1orf162 Gene

    Size:
    155 amino acids
    Molecular mass:
    16886 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for C1orf162 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for C1orf162 Gene

Post-translational modifications for C1orf162 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C1orf162 Gene

No data available for DME Specific Peptides for C1orf162 Gene

Domains & Families for C1orf162 Gene

Protein Domains for C1orf162 Gene

ProtoNet:

Suggested Antigen Peptide Sequences for C1orf162 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C1orf162: view

No data available for Gene Families and UniProtKB/Swiss-Prot for C1orf162 Gene

Function for C1orf162 Gene

genes like me logo Genes that share phenotypes with C1orf162: view

Animal Model Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for C1orf162 Gene

Localization for C1orf162 Gene

Subcellular locations from UniProtKB/Swiss-Prot for C1orf162 Gene

Membrane; Single-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for C1orf162 Gene COMPARTMENTS Subcellular localization image for C1orf162 gene
Compartment Confidence
plasma membrane 2
cytosol 1
endoplasmic reticulum 1
extracellular 1
golgi apparatus 1
mitochondrion 1
nucleus 1

Gene Ontology (GO) - Cellular Components for C1orf162 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with C1orf162: view

Pathways & Interactions for C1orf162 Gene

SuperPathways for C1orf162 Gene

No Data Available

Interacting Proteins for C1orf162 Gene

Selected Interacting proteins: Q8NEQ5-CA162_HUMAN for C1orf162 Gene via IID

Symbol External ID(s) Details
FGL2
MYO1F

Gene Ontology (GO) - Biological Process for C1orf162 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C1orf162 Gene

Transcripts for C1orf162 Gene

Unigene Clusters for C1orf162 Gene

Chromosome 1 open reading frame 162:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C1orf162 Gene

ExUns: 1a · 1b ^ 2a · 2b ^ 3a · 3b ^ 4 ^ 5a · 5b ^ 6a · 6b · 6c
SP1: - - -
SP2: - -
SP3: - - -

Relevant External Links for C1orf162 Gene

GeneLoc Exon Structure for
C1orf162
ECgene alternative splicing isoforms for
C1orf162

Expression for C1orf162 Gene

mRNA expression in normal human tissues for C1orf162 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for C1orf162 Gene

This gene is overexpressed in Whole Blood (x26.8).

Protein differential expression in normal tissues from HIPED for C1orf162 Gene

This gene is overexpressed in NK cells (30.6), Platelet (19.8), and Blymphocyte (18.6).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C1orf162 Gene



Protein tissue co-expression partners for C1orf162 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of C1orf162 Gene:

C1orf162

SOURCE GeneReport for Unigene cluster for C1orf162 Gene:

Hs.288010
genes like me logo Genes that share expression patterns with C1orf162: view

Primer Products

No data available for mRNA Expression by UniProt/SwissProt for C1orf162 Gene

Orthologs for C1orf162 Gene

This gene was present in the common ancestor of mammals.

Orthologs for C1orf162 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C1H1orf162 34 35
  • 99.57 (n)
cow
(Bos Taurus)
Mammalia C3H1orf162 34
  • 75.38 (n)
mouse
(Mus musculus)
Mammalia I830077J02Rik 34 16 35
  • 73.81 (n)
rat
(Rattus norvegicus)
Mammalia LOC100911379 34
  • 73.6 (n)
dog
(Canis familiaris)
Mammalia C17H1orf162 34
  • 66.17 (n)
C1ORF162 35
  • 39 (a)
OneToOne
Species where no ortholog for C1orf162 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C1orf162 Gene

ENSEMBL:
Gene Tree for C1orf162 (if available)
TreeFam:
Gene Tree for C1orf162 (if available)

Paralogs for C1orf162 Gene

No data available for Paralogs for C1orf162 Gene

Variants for C1orf162 Gene

Sequence variations from dbSNP and Humsavar for C1orf162 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs10489793 -- 111,461,500(+) AATAA(C/G)TAAAT upstream-variant-2KB, utr-variant-3-prime
rs10489794 -- 111,465,513(+) GTAAC(A/G)TAGGA upstream-variant-2KB, utr-variant-5-prime
rs1054680 -- 111,478,407(+) GGTAC(A/G)GAGCT utr-variant-3-prime
rs10857883 -- 111,465,320(+) caaaa(C/T)agagg upstream-variant-2KB, utr-variant-5-prime
rs10857884 -- 111,469,517(+) aatac(A/G)gaaaa intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C1orf162 Gene

Variant ID Type Subtype PubMed ID
nsv463250 CNV loss 19166990
nsv547535 CNV loss 21841781

Variation tolerance for C1orf162 Gene

Residual Variation Intolerance Score: 75.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 6.56; 77.90% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C1orf162 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
C1orf162

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C1orf162 Gene

Disorders for C1orf162 Gene

Relevant External Links for C1orf162

Genetic Association Database (GAD)
C1orf162
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C1orf162

No disorders were found for C1orf162 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C1orf162 Gene

Publications for C1orf162 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3 64
  2. A genome-wide association study identifies a novel major locus for glycemic control in type 1 diabetes, as measured by both A1C and glucose. (PMID: 19875614) Paterson A.D. … Bull S.B. (Diabetes 2010) 46 64
  3. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 4 64
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 64
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4 64

Products for C1orf162 Gene

Sources for C1orf162 Gene

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