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Aliases for C1orf162 Gene

Aliases for C1orf162 Gene

  • Chromosome 1 Open Reading Frame 162 2 3 5

External Ids for C1orf162 Gene

Previous GeneCards Identifiers for C1orf162 Gene

  • GC01P111729
  • GC01P111818
  • GC01P112016
  • GC01P109888

Summaries for C1orf162 Gene

GeneCards Summary for C1orf162 Gene

C1orf162 (Chromosome 1 Open Reading Frame 162) is a Protein Coding gene.

Additional gene information for C1orf162 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C1orf162 Gene

Genomics for C1orf162 Gene

Regulatory Elements for C1orf162 Gene

Enhancers for C1orf162 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01H111502 2 FANTOM5 Ensembl ENCODE dbSUPER 19.8 +39.4 39381 8 HDGF PKNOX1 FOXA2 ARNT SIN3A ARID4B DMAP1 ZNF2 YY1 ZNF766 C1orf162 RAP1A DDX20 CEPT1 FAM212B ADORA3 DRAM2
GH01H111591 1.9 FANTOM5 Ensembl ENCODE dbSUPER 9.9 +125.8 125776 3 HNRNPUL1 HDGF ARNT FEZF1 YBX1 ZNF143 ZNF207 FOS SP3 JUNB RAP1A DENND2D TMIGD3 ADORA3 DDX20 C1orf162 FAM212B OVGP1 LINC01160
GH01H111601 1.3 Ensembl ENCODE dbSUPER 10.2 +136.2 136237 4 HDGF PKNOX1 RB1 MAX BACH1 BATF RELA POLR2A EED ATF7 FAM212B RAP1A RNU6-151P KRT18P57 DDX20 C1orf162 LINC01160 PIFO TMIGD3
GH01H111595 1.3 Ensembl ENCODE dbSUPER 9.9 +129.9 129886 3 BACH1 EBF1 RELA EED ETV6 ATF7 RUNX3 ZNF687 HLF ZBED1 RAP1A KRT18P57 RNU6-151P TMIGD3 ADORA3 C1orf162 FAM212B LINC01160
GH01H111599 1.2 ENCODE dbSUPER 10.2 +132.6 132563 1 HDAC1 PKNOX1 RB1 TBL1XR1 ARNT BATF CHAMP1 TCF12 CBX5 GATA2 KRT18P57 RNU6-151P FAM212B DDX20 C1orf162 RAP1A LINC01160 TMIGD3
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around C1orf162 on UCSC Golden Path with GeneCards custom track

Genomic Location for C1orf162 Gene

111,467,487 bp from pter
111,478,512 bp from pter
11,026 bases
Plus strand

Genomic View for C1orf162 Gene

Genes around C1orf162 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C1orf162 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C1orf162 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C1orf162 Gene

Proteins for C1orf162 Gene

  • Protein details for C1orf162 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Transmembrane protein C1orf162
    Protein Accession:
    Secondary Accessions:
    • Q5QNZ1

    Protein attributes for C1orf162 Gene

    155 amino acids
    Molecular mass:
    16886 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for C1orf162 Gene


neXtProt entry for C1orf162 Gene

Post-translational modifications for C1orf162 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C1orf162 Gene

No data available for DME Specific Peptides for C1orf162 Gene

Domains & Families for C1orf162 Gene

Gene Families for C1orf162 Gene

Human Protein Atlas (HPA):
  • Predicted membrane proteins

Protein Domains for C1orf162 Gene


Suggested Antigen Peptide Sequences for C1orf162 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C1orf162: view

No data available for UniProtKB/Swiss-Prot for C1orf162 Gene

Function for C1orf162 Gene

Phenotypes From GWAS Catalog for C1orf162 Gene

genes like me logo Genes that share phenotypes with C1orf162: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for C1orf162
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for C1orf162 Gene

Localization for C1orf162 Gene

Subcellular locations from UniProtKB/Swiss-Prot for C1orf162 Gene

Membrane; Single-pass membrane protein.

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C1orf162 gene
Compartment Confidence
plasma membrane 2
extracellular 1
mitochondrion 1
nucleus 1
endoplasmic reticulum 1
cytosol 1
golgi apparatus 1

Gene Ontology (GO) - Cellular Components for C1orf162 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with C1orf162: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for C1orf162 Gene

Pathways & Interactions for C1orf162 Gene

SuperPathways for C1orf162 Gene

No Data Available

Interacting Proteins for C1orf162 Gene

Selected Interacting proteins: Q8NEQ5-CA162_HUMAN for C1orf162 Gene via IID

Symbol External ID(s) Details

Gene Ontology (GO) - Biological Process for C1orf162 Gene


No data available for Pathways by source and SIGNOR curated interactions for C1orf162 Gene

Drugs & Compounds for C1orf162 Gene

No Compound Related Data Available

Transcripts for C1orf162 Gene

Unigene Clusters for C1orf162 Gene

Chromosome 1 open reading frame 162:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for C1orf162
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for C1orf162 Gene

ExUns: 1a · 1b ^ 2a · 2b ^ 3a · 3b ^ 4 ^ 5a · 5b ^ 6a · 6b · 6c
SP1: - - -
SP2: - -
SP3: - - -

Relevant External Links for C1orf162 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C1orf162 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for C1orf162 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for C1orf162 Gene

This gene is overexpressed in Whole Blood (x26.8).

Protein differential expression in normal tissues from HIPED for C1orf162 Gene

This gene is overexpressed in NK cells (30.6), Platelet (19.8), and Blymphocyte (18.6).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C1orf162 Gene

Protein tissue co-expression partners for C1orf162 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of C1orf162 Gene:


SOURCE GeneReport for Unigene cluster for C1orf162 Gene:


Evidence on tissue expression from TISSUES for C1orf162 Gene

  • Lung(4.3)
genes like me logo Genes that share expression patterns with C1orf162: view

Primer Products

No data available for mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for C1orf162 Gene

Orthologs for C1orf162 Gene

This gene was present in the common ancestor of mammals.

Orthologs for C1orf162 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia C1H1orf162 33 34
  • 99.57 (n)
(Bos Taurus)
Mammalia C3H1orf162 33
  • 75.38 (n)
(Mus musculus)
Mammalia I830077J02Rik 33 16 34
  • 73.81 (n)
(Rattus norvegicus)
Mammalia LOC100911379 33
  • 73.6 (n)
(Canis familiaris)
Mammalia C17H1orf162 33
  • 66.17 (n)
C1ORF162 34
  • 39 (a)
Species where no ortholog for C1orf162 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C1orf162 Gene

Gene Tree for C1orf162 (if available)
Gene Tree for C1orf162 (if available)

Paralogs for C1orf162 Gene

No data available for Paralogs for C1orf162 Gene

Variants for C1orf162 Gene

Sequence variations from dbSNP and Humsavar for C1orf162 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs1000014423 -- 111,465,642(+) TTTAC(C/T)TAAAA upstream-variant-2KB, utr-variant-5-prime
rs1000095505 -- 111,461,111(+) TCCTA(A/T)AAATG upstream-variant-2KB, utr-variant-3-prime
rs1000376188 -- 111,466,803(+) AATTC(C/T)AATTG upstream-variant-2KB, utr-variant-5-prime
rs1000707329 -- 111,465,404(+) TTCTT(C/T)GGCAA upstream-variant-2KB, utr-variant-5-prime
rs1001000095 -- 111,474,309(+) CTTTT(C/T)TTGGC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C1orf162 Gene

Variant ID Type Subtype PubMed ID
nsv463250 CNV loss 19166990
nsv547535 CNV loss 21841781

Variation tolerance for C1orf162 Gene

Residual Variation Intolerance Score: 75.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 6.56; 77.90% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C1orf162 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C1orf162 Gene

Disorders for C1orf162 Gene

Relevant External Links for C1orf162

Genetic Association Database (GAD)
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for C1orf162 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C1orf162 Gene

Publications for C1orf162 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 2 3 60
  2. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 60
  3. A genome-wide association study identifies a novel major locus for glycemic control in type 1 diabetes, as measured by both A1C and glucose. (PMID: 19875614) Paterson AD … Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Research Group (Diabetes 2010) 45 60
  4. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory SG … Prigmore E (Nature 2006) 4 60
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 60

Products for C1orf162 Gene

Sources for C1orf162 Gene

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