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Aliases for C1orf159 Gene

Aliases for C1orf159 Gene

  • Chromosome 1 Open Reading Frame 159 2 3 5

External Ids for C1orf159 Gene

Previous GeneCards Identifiers for C1orf159 Gene

  • GC01M001059
  • GC01M001008
  • GC01M000288
  • GC01M001018

Summaries for C1orf159 Gene

GeneCards Summary for C1orf159 Gene

C1orf159 (Chromosome 1 Open Reading Frame 159) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C1orf159 Gene

Genomics for C1orf159 Gene

Regulatory Elements for C1orf159 Gene

Enhancers for C1orf159 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around C1orf159 on UCSC Golden Path with GeneCards custom track

Promoters for C1orf159 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around C1orf159 on UCSC Golden Path with GeneCards custom track

Genomic Location for C1orf159 Gene

Chromosome:
1
Start:
1,081,818 bp from pter
End:
1,116,361 bp from pter
Size:
34,544 bases
Orientation:
Minus strand

Genomic View for C1orf159 Gene

Genes around C1orf159 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C1orf159 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C1orf159 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C1orf159 Gene

Proteins for C1orf159 Gene

  • Protein details for C1orf159 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96HA4-CA159_HUMAN
    Recommended name:
    Uncharacterized protein C1orf159
    Protein Accession:
    Q96HA4
    Secondary Accessions:
    • B3KQ46
    • Q5T2W6
    • Q6UX67
    • Q6ZR77
    • Q9NWV0

    Protein attributes for C1orf159 Gene

    Size:
    380 amino acids
    Molecular mass:
    40283 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for C1orf159 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for C1orf159 Gene

Proteomics data for C1orf159 Gene at MOPED

Post-translational modifications for C1orf159 Gene

  • Glycosylation at Asn 104, Asn 111, and Asn 128
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for C1orf159 Gene

Domains & Families for C1orf159 Gene

Protein Domains for C1orf159 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for C1orf159 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C1orf159: view

No data available for Gene Families and UniProtKB/Swiss-Prot for C1orf159 Gene

Function for C1orf159 Gene

genes like me logo Genes that share phenotypes with C1orf159: view

Animal Model Products

CRISPR Products

miRNA for C1orf159 Gene

miRTarBase miRNAs that target C1orf159

Inhibitory RNA Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C1orf159 Gene

Localization for C1orf159 Gene

Subcellular locations from UniProtKB/Swiss-Prot for C1orf159 Gene

Membrane; Single-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for C1orf159 Gene COMPARTMENTS Subcellular localization image for C1orf159 gene
Compartment Confidence
extracellular 3
cytosol 2
nucleus 2
plasma membrane 2

No data available for Gene Ontology (GO) - Cellular Components for C1orf159 Gene

Pathways & Interactions for C1orf159 Gene

SuperPathways for C1orf159 Gene

No Data Available

Interacting Proteins for C1orf159 Gene

Gene Ontology (GO) - Biological Process for C1orf159 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C1orf159 Gene

Drugs & Compounds for C1orf159 Gene

No Compound Related Data Available

Transcripts for C1orf159 Gene

Unigene Clusters for C1orf159 Gene

Chromosome 1 open reading frame 159:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C1orf159 Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b ^ 8 ^ 9a · 9b · 9c ^ 10a · 10b · 10c · 10d ^ 11a · 11b ^ 12 ^ 13a · 13b ^ 14a · 14b · 14c ^ 15a ·
SP1: - - - - - - -
SP2: - - - - - - - - - - - - - - - -
SP3: - - - - - - - - - - - - - -
SP4: - - - -
SP5: - - - - - - - -
SP6: - - - - - - - - -
SP7: - - - - - - -
SP8: - - - - - -
SP9: - - - - - - -
SP10: - -
SP11: - - - - - -
SP12: - - - - - - -
SP13: - - - - - - - - - - - - -
SP14: - - - - - - - - -
SP15: - - - - - - - - - -
SP16:
SP17: - - - - - - - -
SP18:

ExUns: 15b ^ 16 ^ 17 ^ 18 ^ 19 ^ 20a · 20b ^ 21
SP1: - -
SP2: - -
SP3: - -
SP4: - -
SP5: - -
SP6:
SP7:
SP8:
SP9:
SP10:
SP11:
SP12:
SP13:
SP14:
SP15:
SP16: -
SP17:
SP18:

Relevant External Links for C1orf159 Gene

GeneLoc Exon Structure for
C1orf159
ECgene alternative splicing isoforms for
C1orf159

Expression for C1orf159 Gene

mRNA expression in normal human tissues for C1orf159 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MOPED, and MaxQB for C1orf159 Gene



SOURCE GeneReport for Unigene cluster for C1orf159 Gene Hs.235095

genes like me logo Genes that share expression patterns with C1orf159: view

Primer Products

No data available for mRNA differential expression in normal tissues , Protein differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for C1orf159 Gene

Orthologs for C1orf159 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C1orf159 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia C16H1orf159 35
  • 75.04 (n)
  • 66.84 (a)
FLJ20584 36
  • 60 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C5H1orf159 35
  • 76.46 (n)
  • 72.16 (a)
C1orf159 36
  • 42 (a)
OneToOne
mouse
(Mus musculus)
Mammalia 9430015G10Rik 35
  • 75.93 (n)
  • 73.33 (a)
9430015G10Rik 16
9430015G10Rik 36
  • 70 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia C1H1orf159 35
  • 96.85 (n)
  • 94.59 (a)
rat
(Rattus norvegicus)
Mammalia RGD1311517 35
  • 76.6 (n)
  • 72.73 (a)
oppossum
(Monodelphis domestica)
Mammalia C1orf159 36
  • 53 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia C1orf159 36
  • 34 (a)
OneToOne
chicken
(Gallus gallus)
Aves C21H1ORF159 35
  • 61.88 (n)
  • 59.67 (a)
C1orf159 36
  • 55 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia C1orf159 36
  • 46 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia c1orf159 35
  • 55.16 (n)
  • 55.95 (a)
zebrafish
(Danio rerio)
Actinopterygii LOC559239 35
  • 49.48 (n)
  • 47.8 (a)
C6H1orf159 36
  • 41 (a)
OneToOne
Species with no ortholog for C1orf159:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C1orf159 Gene

ENSEMBL:
Gene Tree for C1orf159 (if available)
TreeFam:
Gene Tree for C1orf159 (if available)

Paralogs for C1orf159 Gene

No data available for Paralogs for C1orf159 Gene

Variants for C1orf159 Gene

Sequence variations from dbSNP and Humsavar for C1orf159 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs1133647 -- 1,081,961(-) CCCCC(A/C)TCTGA nc-transcript-variant, utr-variant-3-prime
rs2298215 -- 1,083,795(-) AGTCT(C/G)TCATG intron-variant, nc-transcript-variant, utr-variant-3-prime
rs3813203 -- 1,090,481(+) GCTCA(C/T)GCCCA intron-variant
rs3737727 -- 1,087,765(-) GGCCC(C/T)GCCAT intron-variant
rs3737728 -- 1,086,035(-) CCGTC(C/T)GCTCA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C1orf159 Gene

Variant ID Type Subtype PubMed ID
dgv3e1 CNV Complex 17122850
nsv10161 CNV Gain+Loss 18304495
essv2408 CNV CNV 17122850
nsv517709 CNV Gain+Loss 19592680
nsv428334 CNV Gain 18775914
dgv2n67 CNV Gain 20364138
nsv871883 CNV Gain+Loss 21882294
dgv9n71 CNV Loss 21882294
nsv871547 CNV Loss 21882294
dgv10n71 CNV Loss 21882294
dgv11n71 CNV Loss 21882294
dgv12n71 CNV Loss 21882294
dgv13n71 CNV Loss 21882294
nsv509146 CNV Insertion 20534489
nsv870874 CNV Loss 21882294
nsv871349 CNV Loss 21882294
nsv470680 CNV Loss 18288195
nsv870663 CNV Loss 21882294
dgv17n71 CNV Loss 21882294
nsv1409 CNV Insertion 18451855
esv2744030 CNV Deletion 23290073
esv1010559 CNV Gain 20482838
esv23529 CNV Gain 19812545
esv1281251 CNV Insertion 17803354
dgv18n71 CNV Loss 21882294
nsv871553 CNV Loss 21882294
dgv19n71 CNV Loss 21882294
dgv20n71 CNV Loss 21882294
nsv160439 CNV Loss 16902084
esv2744141 CNV Deletion 23290073
nsv870771 CNV Loss 21882294
esv32594 CNV Loss 17666407

Variation tolerance for C1orf159 Gene

Gene Damage Index Score: 1.52; 29.49% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for C1orf159 Gene

Disorders for C1orf159 Gene

Relevant External Links for C1orf159

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C1orf159

No disorders were found for C1orf159 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C1orf159 Gene

Publications for C1orf159 Gene

  1. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PMID: 12975309) Clark H.F. … Gray A.M. (Genome Res. 2003) 2 3 4 67
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  4. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3

Products for C1orf159 Gene

Sources for C1orf159 Gene

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