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Aliases for C1orf158 Gene

Aliases for C1orf158 Gene

  • Chromosome 1 Open Reading Frame 158 2 3 5

External Ids for C1orf158 Gene

Previous GeneCards Identifiers for C1orf158 Gene

  • GC01P012741
  • GC01P011959

Summaries for C1orf158 Gene

GeneCards Summary for C1orf158 Gene

C1orf158 (Chromosome 1 Open Reading Frame 158) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C1orf158 Gene

Genomics for C1orf158 Gene

Regulatory Elements for C1orf158 Gene

Genomic Location for C1orf158 Gene

Chromosome:
1
Start:
12,746,186 bp from pter
End:
12,763,699 bp from pter
Size:
17,514 bases
Orientation:
Plus strand

Genomic View for C1orf158 Gene

Genes around C1orf158 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C1orf158 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C1orf158 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C1orf158 Gene

Proteins for C1orf158 Gene

  • Protein details for C1orf158 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N1D5-CA158_HUMAN
    Recommended name:
    Uncharacterized protein C1orf158
    Protein Accession:
    Q8N1D5
    Secondary Accessions:
    • Q5VUY4

    Protein attributes for C1orf158 Gene

    Size:
    194 amino acids
    Molecular mass:
    23067 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C1orf158 Gene

Proteomics data for C1orf158 Gene at MOPED

Post-translational modifications for C1orf158 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C1orf158 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C1orf158 Gene

Domains & Families for C1orf158 Gene

Protein Domains for C1orf158 Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C1orf158: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C1orf158 Gene

Function for C1orf158 Gene

Phenotypes for C1orf158 Gene

genes like me logo Genes that share phenotypes with C1orf158: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C1orf158 Gene

Localization for C1orf158 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for C1orf158 Gene COMPARTMENTS Subcellular localization image for C1orf158 gene
Compartment Confidence
cytosol 3
nucleus 2
mitochondrion 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C1orf158 Gene

Pathways & Interactions for C1orf158 Gene

SuperPathways for C1orf158 Gene

No Data Available

Interacting Proteins for C1orf158 Gene

Gene Ontology (GO) - Biological Process for C1orf158 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C1orf158 Gene

Drugs & Compounds for C1orf158 Gene

No Compound Related Data Available

Transcripts for C1orf158 Gene

mRNA/cDNA for C1orf158 Gene

Unigene Clusters for C1orf158 Gene

Chromosome 1 open reading frame 158:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for C1orf158 Gene

No ASD Table

Relevant External Links for C1orf158 Gene

GeneLoc Exon Structure for
C1orf158
ECgene alternative splicing isoforms for
C1orf158

Expression for C1orf158 Gene

mRNA expression in normal human tissues for C1orf158 Gene

mRNA differential expression in normal tissues according to GTEx for C1orf158 Gene

This gene is overexpressed in Testis (x34.5) and Fallopian Tube (x4.5).

Protein differential expression in normal tissues from HIPED for C1orf158 Gene

This gene is overexpressed in Plasma (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C1orf158 Gene



SOURCE GeneReport for Unigene cluster for C1orf158 Gene Hs.98095

genes like me logo Genes that share expression patterns with C1orf158: view

Protein tissue co-expression partners for C1orf158 Gene

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for C1orf158 Gene

Orthologs for C1orf158 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C1orf158 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C1H1orf158 35
  • 99.66 (n)
  • 98.97 (a)
C1orf158 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia C16H1orf158 36
  • 78 (a)
OneToOne
C16H1orf158 35
  • 82.21 (n)
  • 79.27 (a)
dog
(Canis familiaris)
Mammalia C2H1orf158 35
  • 80.48 (n)
  • 74.61 (a)
C1orf158 36
  • 72 (a)
OneToOne
mouse
(Mus musculus)
Mammalia 1700012P22Rik 36
  • 74 (a)
OneToOne
1700012P22Rik 35
  • 78.87 (n)
  • 75.26 (a)
1700012P22Rik 16
oppossum
(Monodelphis domestica)
Mammalia C1orf158 36
  • 59 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia C1orf158 36
  • 51 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia LOC691162 35
  • 78.82 (n)
  • 75.52 (a)
chicken
(Gallus gallus)
Aves C21H1orf158 35
  • 56.28 (n)
  • 48.09 (a)
C21H1orf158 36
  • 32 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100490433 35
  • 50 (n)
  • 45.63 (a)
zebrafish
(Danio rerio)
Actinopterygii C11H1orf158 36
  • 34 (a)
OneToOne
LOC100003307 35
  • 50.1 (n)
  • 43.11 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 30 (a)
OneToOne
Species with no ortholog for C1orf158:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C1orf158 Gene

ENSEMBL:
Gene Tree for C1orf158 (if available)
TreeFam:
Gene Tree for C1orf158 (if available)

Paralogs for C1orf158 Gene

No data available for Paralogs for C1orf158 Gene

Variants for C1orf158 Gene

Sequence variations from dbSNP and Humsavar for C1orf158 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs1132185 - 12,760,937(+) ATCCT(C/T)TCCCA reference, missense
rs3000911 -- 12,752,435(-) gctaa(G/T)ttttg intron-variant
rs3000912 -- 12,751,723(-) ctctt(G/T)ttttc intron-variant
rs3000918 -- 12,748,253(-) CTGAA(C/G)CATGC intron-variant
rs3000919 -- 12,746,293(+) AGATG(A/T)CTCCT utr-variant-5-prime

Structural Variations from Database of Genomic Variants (DGV) for C1orf158 Gene

Variant ID Type Subtype PubMed ID
essv17144 CNV CNV 17122850
dgv20e1 CNV Complex 17122850
dgv21e1 CNV Complex 17122850
nsv428410 CNV Gain+Loss 18775914
nsv466394 CNV Gain 19166990
nsv871119 CNV Gain 21882294
essv3598 CNV CNV 17122850
dgv22e1 CNV Complex 17122850
dgv146n71 CNV Gain 21882294
esv2664000 CNV Deletion 23128226
nsv832869 CNV Gain+Loss 17160897
nsv871047 CNV Gain 21882294
dgv23e1 CNV Complex 17122850
nsv470695 CNV Loss 18288195
nsv528703 CNV Loss 19592680

Variation tolerance for C1orf158 Gene

Residual Variation Intolerance Score: 84.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.93; 59.50% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C1orf158 Gene

HapMap Linkage Disequilibrium report
C1orf158

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C1orf158 Gene

Disorders for C1orf158 Gene

Relevant External Links for C1orf158

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C1orf158

No disorders were found for C1orf158 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C1orf158 Gene

Publications for C1orf158 Gene

  1. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4 67
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P. … Vidal M. (Genomics 2007) 3
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3

Products for C1orf158 Gene

Sources for C1orf158 Gene

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