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Aliases for C1orf158 Gene

Aliases for C1orf158 Gene

  • Chromosome 1 Open Reading Frame 158 2 3 5

External Ids for C1orf158 Gene

Previous GeneCards Identifiers for C1orf158 Gene

  • GC01P012741
  • GC01P011959

Summaries for C1orf158 Gene

GeneCards Summary for C1orf158 Gene

C1orf158 (Chromosome 1 Open Reading Frame 158) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C1orf158 Gene

Genomics for C1orf158 Gene

Regulatory Elements for C1orf158 Gene

Enhancers for C1orf158 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around C1orf158 on UCSC Golden Path with GeneCards custom track

Genomic Location for C1orf158 Gene

12,746,186 bp from pter
12,763,699 bp from pter
17,514 bases
Plus strand

Genomic View for C1orf158 Gene

Genes around C1orf158 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C1orf158 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C1orf158 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C1orf158 Gene

Proteins for C1orf158 Gene

  • Protein details for C1orf158 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized protein C1orf158
    Protein Accession:
    Secondary Accessions:
    • Q5VUY4

    Protein attributes for C1orf158 Gene

    194 amino acids
    Molecular mass:
    23067 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C1orf158 Gene

Post-translational modifications for C1orf158 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C1orf158 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C1orf158 Gene

Domains & Families for C1orf158 Gene

Protein Domains for C1orf158 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C1orf158: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C1orf158 Gene

Function for C1orf158 Gene

Phenotypes for C1orf158 Gene

genes like me logo Genes that share phenotypes with C1orf158: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C1orf158 Gene

Localization for C1orf158 Gene

Subcellular locations from

Jensen Localization Image for C1orf158 Gene COMPARTMENTS Subcellular localization image for C1orf158 gene
Compartment Confidence
cytosol 3
nucleus 2
mitochondrion 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C1orf158 Gene

Pathways & Interactions for C1orf158 Gene

SuperPathways for C1orf158 Gene

No Data Available

Interacting Proteins for C1orf158 Gene

Gene Ontology (GO) - Biological Process for C1orf158 Gene


No data available for Pathways by source and SIGNOR curated interactions for C1orf158 Gene

Drugs & Compounds for C1orf158 Gene

No Compound Related Data Available

Transcripts for C1orf158 Gene

mRNA/cDNA for C1orf158 Gene

Unigene Clusters for C1orf158 Gene

Chromosome 1 open reading frame 158:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C1orf158 Gene

No ASD Table

Relevant External Links for C1orf158 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C1orf158 Gene

mRNA expression in normal human tissues for C1orf158 Gene

mRNA differential expression in normal tissues according to GTEx for C1orf158 Gene

This gene is overexpressed in Testis (x34.5) and Fallopian Tube (x4.5).

Protein differential expression in normal tissues from HIPED for C1orf158 Gene

This gene is overexpressed in Plasma (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C1orf158 Gene

Protein tissue co-expression partners for C1orf158 Gene

NURSA nuclear receptor signaling pathways regulating expression of C1orf158 Gene:


SOURCE GeneReport for Unigene cluster for C1orf158 Gene:

genes like me logo Genes that share expression patterns with C1orf158: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for C1orf158 Gene

Orthologs for C1orf158 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C1orf158 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia C16H1orf158 34
  • 82.21 (n)
  • 79.27 (a)
C16H1orf158 35
  • 78 (a)
(Canis familiaris)
Mammalia C2H1orf158 34
  • 80.48 (n)
  • 74.61 (a)
C1orf158 35
  • 72 (a)
(Mus musculus)
Mammalia 1700012P22Rik 34
  • 78.87 (n)
  • 75.26 (a)
1700012P22Rik 16
1700012P22Rik 35
  • 74 (a)
(Pan troglodytes)
Mammalia C1H1orf158 34
  • 99.66 (n)
  • 98.97 (a)
C1orf158 35
  • 99 (a)
(Rattus norvegicus)
Mammalia LOC691162 34
  • 78.82 (n)
  • 75.52 (a)
(Monodelphis domestica)
Mammalia C1orf158 35
  • 59 (a)
(Ornithorhynchus anatinus)
Mammalia C1orf158 35
  • 51 (a)
(Gallus gallus)
Aves C21H1orf158 34
  • 56.28 (n)
  • 48.09 (a)
C21H1orf158 35
  • 32 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100490433 34
  • 50 (n)
  • 45.63 (a)
(Danio rerio)
Actinopterygii LOC100003307 34
  • 50.1 (n)
  • 43.11 (a)
C11H1orf158 35
  • 34 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 35
  • 30 (a)
Species where no ortholog for C1orf158 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C1orf158 Gene

Gene Tree for C1orf158 (if available)
Gene Tree for C1orf158 (if available)

Paralogs for C1orf158 Gene

No data available for Paralogs for C1orf158 Gene

Variants for C1orf158 Gene

Sequence variations from dbSNP and Humsavar for C1orf158 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs1132185 - 12,760,937(+) ATCCT(C/T)TCCCA reference, missense
rs1132187 -- 12,760,983(+) ATAGA(A/G)TCAGC utr-variant-3-prime
rs3000906 -- 12,756,465(-) GAGAC(A/G)GCTTT intron-variant
rs3000907 -- 12,756,421(-) CTCTG(A/G)CACAA intron-variant
rs3000908 -- 12,756,416(-) ACACA(A/C)CAAGT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C1orf158 Gene

Variant ID Type Subtype PubMed ID
dgv19n100 CNV loss 25217958
esv2664000 CNV deletion 23128226
esv3585239 CNV loss 21293372
nsv1000876 CNV gain 25217958
nsv1011540 CNV loss 25217958
nsv466394 CNV gain 19166990
nsv470695 CNV loss 18288195
nsv528703 CNV loss 19592680
nsv545445 CNV gain 21841781
nsv832869 CNV gain+loss 17160897
nsv999658 CNV gain 25217958

Variation tolerance for C1orf158 Gene

Residual Variation Intolerance Score: 84.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.93; 59.50% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C1orf158 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C1orf158 Gene

Disorders for C1orf158 Gene

Relevant External Links for C1orf158

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for C1orf158 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C1orf158 Gene

Publications for C1orf158 Gene

  1. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4 65
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 65
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3 65
  4. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P. … Vidal M. (Genomics 2007) 3 65

Products for C1orf158 Gene

Sources for C1orf158 Gene

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