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Aliases for C1orf146 Gene

Aliases for C1orf146 Gene

  • Chromosome 1 Open Reading Frame 146 2 3 5

External Ids for C1orf146 Gene

Previous GeneCards Identifiers for C1orf146 Gene

  • GC01P092397
  • GC01P092456
  • GC01P092683
  • GC01P090803

Summaries for C1orf146 Gene

GeneCards Summary for C1orf146 Gene

C1orf146 (Chromosome 1 Open Reading Frame 146) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C1orf146 Gene

Genomics for C1orf146 Gene

Regulatory Elements for C1orf146 Gene

Enhancers for C1orf146 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around C1orf146 on UCSC Golden Path with GeneCards custom track

Genomic Location for C1orf146 Gene

Chromosome:
1
Start:
92,217,912 bp from pter
End:
92,245,813 bp from pter
Size:
27,902 bases
Orientation:
Plus strand

Genomic View for C1orf146 Gene

Genes around C1orf146 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C1orf146 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C1orf146 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C1orf146 Gene

Proteins for C1orf146 Gene

  • Protein details for C1orf146 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5VVC0-CA146_HUMAN
    Recommended name:
    Uncharacterized protein C1orf146
    Protein Accession:
    Q5VVC0
    Secondary Accessions:
    • Q5VVC4

    Protein attributes for C1orf146 Gene

    Size:
    180 amino acids
    Molecular mass:
    20418 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=CAH70760.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

neXtProt entry for C1orf146 Gene

Proteomics data for C1orf146 Gene at MOPED

Post-translational modifications for C1orf146 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C1orf146 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C1orf146 Gene

Domains & Families for C1orf146 Gene

Protein Domains for C1orf146 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C1orf146: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C1orf146 Gene

Function for C1orf146 Gene

Phenotypes for C1orf146 Gene

genes like me logo Genes that share phenotypes with C1orf146: view

Animal Model Products

CRISPR Products

miRNA for C1orf146 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C1orf146 Gene

Localization for C1orf146 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for C1orf146 Gene COMPARTMENTS Subcellular localization image for C1orf146 gene
Compartment Confidence
cytosol 2
nucleus 2
extracellular 1
peroxisome 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C1orf146 Gene

Pathways & Interactions for C1orf146 Gene

SuperPathways for C1orf146 Gene

No Data Available

Interacting Proteins for C1orf146 Gene

Gene Ontology (GO) - Biological Process for C1orf146 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C1orf146 Gene

Drugs & Compounds for C1orf146 Gene

No Compound Related Data Available

Transcripts for C1orf146 Gene

mRNA/cDNA for C1orf146 Gene

(3) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(10) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for C1orf146 Gene

Chromosome 1 open reading frame 146:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for C1orf146 Gene

No ASD Table

Relevant External Links for C1orf146 Gene

GeneLoc Exon Structure for
C1orf146
ECgene alternative splicing isoforms for
C1orf146

Expression for C1orf146 Gene

mRNA expression in normal human tissues for C1orf146 Gene

mRNA differential expression in normal tissues according to GTEx for C1orf146 Gene

This gene is overexpressed in Testis (x22.9), Brain - Cerebellar Hemisphere (x5.2), and Brain - Cerebellum (x4.2).

SOURCE GeneReport for Unigene cluster for C1orf146 Gene Hs.558823

genes like me logo Genes that share expression patterns with C1orf146: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for C1orf146 Gene

Orthologs for C1orf146 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C1orf146 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia C3H1orf146 35
  • 93.33 (n)
  • 91.67 (a)
C1orf146 36
  • 91 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C6H1orf146 35
  • 92.78 (n)
  • 88.89 (a)
C1orf146 36
  • 88 (a)
OneToOne
mouse
(Mus musculus)
Mammalia 1700028K03Rik 35
  • 85.98 (n)
  • 84.09 (a)
1700028K03Rik 16
1700028K03Rik 36
  • 81 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia C1H1orf146 35
  • 100 (n)
  • 100 (a)
C1orf146 36
  • 100 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia LOC689986 35
  • 84.92 (n)
  • 79.33 (a)
oppossum
(Monodelphis domestica)
Mammalia C1orf146 36
  • 51 (a)
OneToOne
chicken
(Gallus gallus)
Aves C1ORF146 35
  • 66.87 (n)
  • 59.64 (a)
C1ORF146 36
  • 56 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia C1orf146 36
  • 60 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC101733338 35
  • 63.92 (n)
  • 54.71 (a)
zebrafish
(Danio rerio)
Actinopterygii gb:ex154042 35
  • 50.46 (n)
  • 41.78 (a)
C6H1orf146 36
  • 40 (a)
OneToOne
Species with no ortholog for C1orf146:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C1orf146 Gene

ENSEMBL:
Gene Tree for C1orf146 (if available)
TreeFam:
Gene Tree for C1orf146 (if available)

Paralogs for C1orf146 Gene

Pseudogenes.org Pseudogenes for C1orf146 Gene

genes like me logo Genes that share paralogs with C1orf146: view

No data available for Paralogs for C1orf146 Gene

Variants for C1orf146 Gene

Sequence variations from dbSNP and Humsavar for C1orf146 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs1825813 -- 92,243,416(+) ATCTC(A/G)GCTCA intron-variant
rs2046617 -- 92,239,393(+) TAATT(C/G)TGTAA intron-variant
rs2046618 -- 92,240,302(+) AATTT(C/G)TGTGT intron-variant
rs3122319 -- 92,238,350(+) TTTTG(G/T)TTTGG intron-variant
rs3122320 -- 92,240,081(+) tgcTC(C/T)AGAGA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C1orf146 Gene

Variant ID Type Subtype PubMed ID
esv2714684 CNV Deletion 23290073
nsv871508 CNV Gain 21882294
nsv830592 CNV Gain 17160897
nsv870667 CNV Loss 21882294

Variation tolerance for C1orf146 Gene

Residual Variation Intolerance Score: 61.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.72; 32.73% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for C1orf146 Gene

Disorders for C1orf146 Gene

Relevant External Links for C1orf146

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C1orf146

No disorders were found for C1orf146 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C1orf146 Gene

Publications for C1orf146 Gene

  1. Finishing the euchromatic sequence of the human genome. (PMID: 15496913) (Nature 2004) 2 3 67
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for C1orf146 Gene

Sources for C1orf146 Gene

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