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Aliases for C1orf145 Gene

Subcategory (RNA class) for C1orf145 Gene


Quality Score for this RNA gene is


Aliases for C1orf145 Gene

  • Chromosome 1 Open Reading Frame 145 2 3 5

External Ids for C1orf145 Gene

Previous GeneCards Identifiers for C1orf145 Gene

  • GC01U901147
  • GC01M226457
  • GC01M228391

Summaries for C1orf145 Gene

GeneCards Summary for C1orf145 Gene

C1orf145 (Chromosome 1 Open Reading Frame 145) is an RNA Gene, and is affiliated with the ncRNA class.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C1orf145 Gene

Genomics for C1orf145 Gene

Regulatory Elements for C1orf145 Gene

Enhancers for C1orf145 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01F228137 1.4 Ensembl ENCODE 16.6 +71.6 71600 8.8 HDGF PKNOX1 ARNT CREB3L1 ARID4B SIN3A DMAP1 YY1 ZNF143 ZNF548 OBSCN CICP26 ENSG00000269890 C1orf145 C1orf35 FAM96AP2 MRPL55 DUSP5P1 ENSG00000231563 RPL23AP15
GH01F227933 1.2 Ensembl ENCODE 14.2 +278.7 278666 2.6 ATF1 PKNOX1 INSM2 KLF17 ZEB1 ZNF391 FOS CREM ZNF280D SP3 CICP26 OBSCN C1orf145 HIST3H3 ENSG00000269890 MIR5008 PRSS38
GH01F228500 1.5 FANTOM5 Ensembl ENCODE 10.7 -287.2 -287237 1.8 WRNIP1 ARID4B SIN3A DMAP1 ZNF48 ZNF143 REST TBX21 KAT8 CREB3 HIST3H2A HIST3H2BB RPL23AP15 C1orf35 C1orf145 OBSCN RNF187 LOC105373124 ENSG00000279306
GH01F228130 1.3 Ensembl ENCODE 11.3 +82.1 82053 2.0 ATF1 PKNOX1 ARID4B GLI4 YBX1 ZNF2 ZNF121 GLIS2 ZNF143 KLF7 CICP26 ENSG00000269890 C1orf35 HIST3H3 OBSCN C1orf145 RPL23AP15 HIST3H2A HIST3H2BB ENSG00000231563
GH01F227942 1.1 ENCODE 12.9 +267.9 267948 6.0 HDGF PKNOX1 ARNT ARID4B SIN3A DMAP1 ZNF2 ZNF143 FOS KLF13 C1orf145 WNT3A OBSCN IBA57 ENSG00000269934 MRPL55 MIR5008 WNT9A
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around C1orf145 on UCSC Golden Path with GeneCards custom track

Promoters for C1orf145 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000289771 64 1601 ATF1 ZNF133 ARID4B SIN3A GLI4 YBX1 ZNF48 ZNF2 ETS1 GLIS2

Genomic Location for C1orf145 Gene

228,203,506 bp from pter
228,213,664 bp from pter
10,159 bases
Minus strand

Genomic View for C1orf145 Gene

Genes around C1orf145 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C1orf145 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C1orf145 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C1orf145 Gene

Proteins for C1orf145 Gene

  • Protein details for C1orf145 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Putative uncharacterized protein C1orf145
    Protein Accession:
    Secondary Accessions:
    • Q5T438
    • Q8N372

    Protein attributes for C1orf145 Gene

    158 amino acids
    Molecular mass:
    17524 Da
    Quaternary structure:
    No Data Available
    • Sequence=CAI15073.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

    Alternative splice isoforms for C1orf145 Gene


neXtProt entry for C1orf145 Gene

Post-translational modifications for C1orf145 Gene

No Post-translational modifications

Other Protein References for C1orf145 Gene

No data available for DME Specific Peptides for C1orf145 Gene

Domains & Families for C1orf145 Gene

Protein Domains for C1orf145 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C1orf145: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C1orf145 Gene

Function for C1orf145 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for C1orf145 Gene

Localization for C1orf145 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C1orf145 gene
Compartment Confidence
nucleus 3
mitochondrion 2
extracellular 1
peroxisome 1
cytosol 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C1orf145 Gene

Pathways & Interactions for C1orf145 Gene

SuperPathways for C1orf145 Gene

No Data Available

Interacting Proteins for C1orf145 Gene

Gene Ontology (GO) - Biological Process for C1orf145 Gene


No data available for Pathways by source and SIGNOR curated interactions for C1orf145 Gene

Transcripts for C1orf145 Gene

mRNA/cDNA for C1orf145 Gene

(1) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for C1orf145 Gene

Chromosome 1 open reading frame 145:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for C1orf145 Gene

No ASD Table

Relevant External Links for C1orf145 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C1orf145 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for C1orf145 Gene

mRNA differential expression in normal tissues according to GTEx for C1orf145 Gene

This gene is overexpressed in Brain - Putamen (basal ganglia) (x10.1), Brain - Caudate (basal ganglia) (x9.9), and Brain - Nucleus accumbens (basal ganglia) (x8.8).

NURSA nuclear receptor signaling pathways regulating expression of C1orf145 Gene:


SOURCE GeneReport for Unigene cluster for C1orf145 Gene:

genes like me logo Genes that share expression patterns with C1orf145: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for C1orf145 Gene

Orthologs for C1orf145 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for C1orf145 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia C1orf145 35
  • 100 (a)
Species where no ortholog for C1orf145 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C1orf145 Gene

Gene Tree for C1orf145 (if available)
Gene Tree for C1orf145 (if available)

Paralogs for C1orf145 Gene

No data available for Paralogs for C1orf145 Gene

Variants for C1orf145 Gene

Sequence variations from dbSNP and Humsavar for C1orf145 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs199979779 Uncertain significance 228,212,510(+) GCACC(C/G)GCACG intron-variant, nc-transcript-variant, reference, missense
rs10799470 -- 228,208,920(+) GGGGG(A/G)GCGTC intron-variant
rs10799471 -- 228,210,845(+) AGTGG(A/G)GGGGC intron-variant
rs111238500 -- 228,209,898(+) ATTAC(A/G)TGTGC intron-variant
rs111275189 -- 228,211,449(+) GCTAG(C/G)GGGTG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C1orf145 Gene

Variant ID Type Subtype PubMed ID
nsv952138 CNV deletion 24416366
nsv827019 CNV loss 20364138
nsv826908 CNV gain 20364138
nsv523935 CNV loss 19592680
nsv474639 CNV novel sequence insertion 20440878
nsv1160102 CNV deletion 26073780
nsv1143478 CNV deletion 24896259
nsv1069355 CNV deletion 25765185
esv32853 CNV gain 17666407

Variation tolerance for C1orf145 Gene

Gene Damage Index Score: 3.74; 57.75% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C1orf145 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C1orf145 Gene

Disorders for C1orf145 Gene

Relevant External Links for C1orf145

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for C1orf145 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C1orf145 Gene

Publications for C1orf145 Gene

  1. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4 64
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64
  5. Shotgun sequencing of the human transcriptome with ORF expressed sequence tags. (PMID: 10737800) Dias Neto E. … Simpson A.J.G. (Proc. Natl. Acad. Sci. U.S.A. 2000) 3 64

Products for C1orf145 Gene

Sources for C1orf145 Gene

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