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Aliases for C1orf143 Gene

Subcategory (RNA class) for C1orf143 Gene


Quality Score for this RNA gene is


Aliases for C1orf143 Gene

  • Chromosome 1 Open Reading Frame 143 2 3 5

External Ids for C1orf143 Gene

Previous GeneCards Identifiers for C1orf143 Gene

  • GC01P215072
  • GC01U901251
  • GC01P218684

Summaries for C1orf143 Gene

GeneCards Summary for C1orf143 Gene

C1orf143 (Chromosome 1 Open Reading Frame 143) is an RNA Gene, and is affiliated with the ncRNA class.

Additional gene information for C1orf143 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C1orf143 Gene

Genomics for C1orf143 Gene

Regulatory Elements for C1orf143 Gene

Enhancers for C1orf143 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01H218373 1.8 FANTOM5 Ensembl ENCODE dbSUPER 10.8 -134.2 -134243 4 FOXA2 SIN3A FEZF1 BRCA1 GLIS2 FOS RUNX3 SP3 JUNB TSHZ1 RRP15 TGFB2-AS1 TGFB2 C1orf143 GC01M218380
GH01H218487 1.5 FANTOM5 Ensembl ENCODE dbSUPER 12.8 -21.2 -21238 3 SMARCA5 PKNOX1 ZNF362 NFIB JUN YBX1 ZNF384 BMI1 FOXA1 ZNF217 TGFB2 C1orf143 TGFB2-AS1 GC01P218475 GC01P218504
GH01H218472 1.7 FANTOM5 Ensembl ENCODE dbSUPER 11.2 -31.9 -31890 10 PKNOX1 FOXA2 NFIB SIN3A BMI1 ZBTB40 ZEB1 RFX5 ZNF366 RCOR1 TGFB2 C1orf143 TGFB2-AS1 RRP15 GC01P218475 GC01P218504
GH01H218584 1.4 FANTOM5 Ensembl ENCODE 10.4 +75.6 75597 2 TBP RAD21 BRCA1 GLIS2 ZNF366 FOS SMARCC1 CEBPB ZEB2 SMARCA4 C1orf143 GC01M218543 GC01P218626
GH01H218400 1.3 Ensembl ENCODE dbSUPER 10.3 -108.0 -107985 3 SOX13 TFAP4 FOXA2 ARID4B RARA GATA3 RERE NR2F6 CREM THAP11 TGFB2 TGFB2-AS1 C1orf143 GC01P218405 GC01M218380
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around C1orf143 on UCSC Golden Path with GeneCards custom track

Genomic Location for C1orf143 Gene

218,510,096 bp from pter
218,525,978 bp from pter
15,883 bases
Plus strand

Genomic View for C1orf143 Gene

Genes around C1orf143 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C1orf143 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C1orf143 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

No data available for RefSeq DNA sequence for C1orf143 Gene

Proteins for C1orf143 Gene

Post-translational modifications for C1orf143 Gene

No Post-translational modifications

No data available for DME Specific Peptides for C1orf143 Gene

Domains & Families for C1orf143 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C1orf143 Gene

Function for C1orf143 Gene

Phenotypes From GWAS Catalog for C1orf143 Gene

Animal Model Products

CRISPR Products

Clone Products

  • Applied Biological Materials Clones for C1orf143
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for C1orf143 Gene

Localization for C1orf143 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C1orf143 gene
Compartment Confidence
extracellular 2
cytosol 2
plasma membrane 1
nucleus 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for C1orf143 Gene

Pathways & Interactions for C1orf143 Gene

SuperPathways for C1orf143 Gene

No Data Available

Interacting Proteins for C1orf143 Gene

Gene Ontology (GO) - Biological Process for C1orf143 Gene


No data available for Pathways by source and SIGNOR curated interactions for C1orf143 Gene

Drugs & Compounds for C1orf143 Gene

No Compound Related Data Available

Transcripts for C1orf143 Gene

mRNA/cDNA for C1orf143 Gene

(8) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

Clone Products

  • Applied Biological Materials Clones for C1orf143
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for C1orf143 Gene

No ASD Table

Relevant External Links for C1orf143 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C1orf143 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for C1orf143 Gene

mRNA differential expression in normal tissues according to GTEx for C1orf143 Gene

This gene is overexpressed in Brain - Hypothalamus (x6.5), Brain - Hippocampus (x6.0), Brain - Amygdala (x5.9), Brain - Nucleus accumbens (basal ganglia) (x5.6), and Brain - Frontal Cortex (BA9) (x4.1).

NURSA nuclear receptor signaling pathways regulating expression of C1orf143 Gene:

genes like me logo Genes that share expression patterns with C1orf143: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for C1orf143 Gene

Orthologs for C1orf143 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for C1orf143 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia C1orf143 34
  • 96 (a)
Species where no ortholog for C1orf143 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C1orf143 Gene

Gene Tree for C1orf143 (if available)
Gene Tree for C1orf143 (if available)

Paralogs for C1orf143 Gene

No data available for Paralogs for C1orf143 Gene

Variants for C1orf143 Gene

Variation tolerance for C1orf143 Gene

Gene Damage Index Score: 3.49; 55.24% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C1orf143 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Structural Variations from Database of Genomic Variants (DGV) for C1orf143 Gene

Disorders for C1orf143 Gene

Relevant External Links for C1orf143

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for C1orf143 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C1orf143 Gene

Publications for C1orf143 Gene

  1. The sequence of the human genome. (PMID: 11181995) Venter JC … Zhu X (Science (New York, N.Y.) 2001) 3 60
  2. Creation of genome-wide protein expression libraries using random activation of gene expression. (PMID: 11329013) Harrington JJ … Ducar M (Nature biotechnology 2001) 3 60

Products for C1orf143 Gene

Sources for C1orf143 Gene

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