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Aliases for C1orf137 Gene

Aliases for C1orf137 Gene

  • Chromosome 1 Open Reading Frame 137 2 3 5

External Ids for C1orf137 Gene

Previous GeneCards Identifiers for C1orf137 Gene

  • GC01P116950
  • GC01P117038
  • GC01U902252
  • GC01P117236

Summaries for C1orf137 Gene

GeneCards Summary for C1orf137 Gene

C1orf137 (Chromosome 1 Open Reading Frame 137) is a Protein Coding gene.

Additional gene information for C1orf137 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C1orf137 Gene

Genomics for C1orf137 Gene

Regulatory Elements for C1orf137 Gene

Enhancers for C1orf137 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01H116777 1.3 Ensembl ENCODE dbSUPER 10 +84.0 84029 1.2 FOXA2 MAX EBF1 CEBPG RARA FOSL1 LCORL FOS IKZF2 GATAD2A CD2 CD101 C1orf137 FTH1P22 LOC105378927
GH01H116645 1.1 Ensembl ENCODE 10.9 -46.4 -46440 3.8 HDGF FOXA2 SIN3A KLF17 FEZF1 YY1 FOS ATF7 ZEB2 ZNF217 IGSF3 MIR320B1 C1orf137 CD101 LOC105378924
GH01H116594 1.1 Ensembl ENCODE 10.4 -97.1 -97061 4.3 HDGF ARNT BMI1 RAD21 TCF12 ZSCAN5C SCRT2 ZNF143 ATF7 IKZF2 CD58 IGSF3 MIR320B1 C1orf137 LOC105378924
GH01H117050 1 Ensembl ENCODE 9.6 +357.6 357610 1.8 HDGF PKNOX1 ZNF687 ZBED1 BACH1 ZNF175 ZNF407 ELF1 GATA3 POLR2A CD101 CD2 CD58 TRIM45 C1orf137 PIR49222 LOC101929099
GH01H116885 0.9 Ensembl ENCODE 9.4 +192.6 192642 1.7 ZNF362 ZBTB21 JUN ZNF518A ATF2 ZFHX2 ZNF341 ZNF629 SCRT2 ZNF600 CD101 PTGFRN CD2 C1orf137 LOC105378927 ENSG00000272715
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around C1orf137 on UCSC Golden Path with GeneCards custom track

Genomic Locations for C1orf137 Gene

Genomic Locations for C1orf137 Gene
12,492 bases
Plus strand

Genomic View for C1orf137 Gene

Genes around C1orf137 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C1orf137 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C1orf137 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C1orf137 Gene

Proteins for C1orf137 Gene

  • Protein details for C1orf137 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Putative uncharacterized protein C1orf137
    Protein Accession:

    Protein attributes for C1orf137 Gene

    98 amino acids
    Molecular mass:
    10987 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C1orf137 Gene

Post-translational modifications for C1orf137 Gene

No Post-translational modifications

Other Protein References for C1orf137 Gene

REFSEQ proteins:

No data available for DME Specific Peptides for C1orf137 Gene

Domains & Families for C1orf137 Gene

Protein Domains for C1orf137 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C1orf137: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C1orf137 Gene

Function for C1orf137 Gene

Phenotypes From GWAS Catalog for C1orf137 Gene

Animal Model Products

Inhibitory RNA Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for C1orf137 Gene

Localization for C1orf137 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C1orf137 gene
Compartment Confidence
extracellular 2
nucleus 1
cytosol 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for C1orf137 Gene

Pathways & Interactions for C1orf137 Gene

SuperPathways for C1orf137 Gene

No Data Available

Interacting Proteins for C1orf137 Gene

Gene Ontology (GO) - Biological Process for C1orf137 Gene


No data available for Pathways by source and SIGNOR curated interactions for C1orf137 Gene

Drugs & Compounds for C1orf137 Gene

No Compound Related Data Available

Transcripts for C1orf137 Gene

mRNA/cDNA for C1orf137 Gene

(1) REFSEQ mRNAs :
(1) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Inhibitory RNA Products

Alternative Splicing Database (ASD) splice patterns (SP) for C1orf137 Gene

No ASD Table

Relevant External Links for C1orf137 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C1orf137 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for C1orf137 Gene

NURSA nuclear receptor signaling pathways regulating expression of C1orf137 Gene:

genes like me logo Genes that share expression patterns with C1orf137: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for C1orf137 Gene

Orthologs for C1orf137 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for C1orf137 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia C1orf137 34
  • 100 (a)
LOC101059503 33
  • 99.66 (n)
Species where no ortholog for C1orf137 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C1orf137 Gene

Gene Tree for C1orf137 (if available)
Gene Tree for C1orf137 (if available)

Paralogs for C1orf137 Gene

No data available for Paralogs for C1orf137 Gene

Variants for C1orf137 Gene

Sequence variations from dbSNP and Humsavar for C1orf137 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs1000115615 -- 116,693,074(+) TAGGG(A/C)AAACA upstream-variant-2KB
rs1000354200 -- 116,705,253(+) AATTT(A/T)TCTGT intron-variant
rs1000531267 -- 116,693,295(+) CCCTG(A/C)CAGAC upstream-variant-2KB
rs1000808912 -- 116,705,578(+) CCAGG(A/C)ACAGT intron-variant
rs1000851608 -- 116,701,020(+) CTAAT(A/C)GTTTG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C1orf137 Gene

Variant ID Type Subtype PubMed ID
nsv831148 CNV gain 17160897
nsv473513 CNV novel sequence insertion 20440878
nsv428190 CNV gain 18775914
esv2758963 CNV gain+loss 17122850

Variation tolerance for C1orf137 Gene

Gene Damage Index Score: 0.06; 1.30% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C1orf137 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C1orf137 Gene

Disorders for C1orf137 Gene

Relevant External Links for C1orf137

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for C1orf137 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C1orf137 Gene

Publications for C1orf137 Gene

  1. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory SG … Prigmore E (Nature 2006) 4 60

Products for C1orf137 Gene

Sources for C1orf137 Gene

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