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Aliases for C1orf127 Gene

Aliases for C1orf127 Gene

  • Chromosome 1 Open Reading Frame 127 2 3

External Ids for C1orf127 Gene

Previous GeneCards Identifiers for C1orf127 Gene

  • GC01M010941
  • GC01M010159
  • GC01M011006

Summaries for C1orf127 Gene

GeneCards Summary for C1orf127 Gene

C1orf127 (Chromosome 1 Open Reading Frame 127) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C1orf127 Gene

Genomics for C1orf127 Gene

Regulatory Elements for C1orf127 Gene

Genomic Location for C1orf127 Gene

10,946,471 bp from pter
10,982,037 bp from pter
35,567 bases
Minus strand

Genomic View for C1orf127 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for C1orf127 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C1orf127 Gene

Proteins for C1orf127 Gene

  • Protein details for C1orf127 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized protein C1orf127
    Protein Accession:
    Secondary Accessions:
    • A0AVG8
    • A6NKM7
    • Q5VXJ2

    Protein attributes for C1orf127 Gene

    656 amino acids
    Molecular mass:
    69787 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for C1orf127 Gene


neXtProt entry for C1orf127 Gene

Proteomics data for C1orf127 Gene at MOPED

Post-translational modifications for C1orf127 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C1orf127 Gene

Antibody Products

No data available for DME Specific Peptides for C1orf127 Gene

Domains for C1orf127 Gene

Protein Domains for C1orf127 Gene


Suggested Antigen Peptide Sequences for C1orf127 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C1orf127: view

No data available for Gene Families and UniProtKB/Swiss-Prot for C1orf127 Gene

Function for C1orf127 Gene

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C1orf127

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for C1orf127 Gene

Localization for C1orf127 Gene

Subcellular locations from

Jensen Localization Image for C1orf127 Gene COMPARTMENTS Subcellular localization image for C1orf127 gene
Compartment Confidence
mitochondrion 3
cytosol 1
nucleus 1
plasma membrane 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C1orf127 Gene

Pathways for C1orf127 Gene

SuperPathways for C1orf127 Gene

No Data Available

Interacting Proteins for C1orf127 Gene

Gene Ontology (GO) - Biological Process for C1orf127 Gene


No data available for Pathways by source for C1orf127 Gene

Transcripts for C1orf127 Gene

mRNA/cDNA for C1orf127 Gene

Unigene Clusters for C1orf127 Gene

Chromosome 1 open reading frame 127:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C1orf127

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C1orf127 Gene

ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9a · 9b · 9c ^ 10a · 10b · 10c
SP1: - - - -
SP4: -

Relevant External Links for C1orf127 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C1orf127 Gene

mRNA expression in normal human tissues for C1orf127 Gene

mRNA differential expression in normal tissues according to GTEx for C1orf127 Gene

This gene is overexpressed in Muscle - Skeletal (16.3), Pancreas (8.6), and Brain - Cerebellum (5.1).

Protein differential expression in normal tissues for C1orf127 Gene

This gene is overexpressed in Platelet (69.0).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for C1orf127 Gene

SOURCE GeneReport for Unigene cluster for C1orf127 Gene Hs.127026

genes like me logo Genes that share expressions with C1orf127: view

Expression partners for C1orf127 Gene

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for C1orf127 Gene

Orthologs for C1orf127 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C1orf127 Gene

Organism Taxonomy Gene Similarity Type Details
(Mus musculus)
Mammalia Gm572 35
  • 77.93 (n)
  • 68.96 (a)
Gm572 16
Gm572 36
  • 63 (a)
(Pan troglodytes)
Mammalia C1H1orf127 35
  • 98.3 (n)
  • 97.33 (a)
C1orf127 36
  • 97 (a)
(Rattus norvegicus)
Mammalia LOC691354 35
  • 73.66 (n)
  • 62.94 (a)
(Monodelphis domestica)
Mammalia C1orf127 36
  • 60 (a)
(Danio rerio)
Actinopterygii LOC101883649 35
  • 48.8 (n)
  • 38 (a)
C23H1orf127 36
  • 34 (a)
Species with no ortholog for C1orf127:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C1orf127 Gene

Gene Tree for C1orf127 (if available)
Gene Tree for C1orf127 (if available)

Paralogs for C1orf127 Gene

No data available for Paralogs for C1orf127 Gene

Variants for C1orf127 Gene

Sequence variations from dbSNP and Humsavar for C1orf127 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs1122112 -- 10,950,515(-) GGTGG(G/T)CAGGC intron-variant
rs1281005 -- 10,951,567(-) ttaaa(C/T)ttttt intron-variant
rs1281006 -- 10,951,156(-) gtgcc(C/T)ggccT intron-variant
rs1281007 -- 10,950,975(-) GAACC(C/T)GCAGC intron-variant
rs1281008 -- 10,950,945(-) GAGCA(A/G)CCTCG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C1orf127 Gene

Variant ID Type Subtype PubMed ID
dgv19e1 CNV Complex 17122850
nsv832425 CNV Loss 17160897
nsv508869 CNV Insertion 20534489
esv2672799 CNV Deletion 23128226

Relevant External Links for C1orf127 Gene

HapMap Linkage Disequilibrium report
Human Gene Mutation Database (HGMD)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C1orf127 Gene

Disorders for C1orf127 Gene

Relevant External Links for C1orf127

Genetic Association Database (GAD)

No disorders were found for C1orf127 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for C1orf127 Gene

Publications for C1orf127 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 2 3 4
  2. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  3. Six novel susceptibility Loci for early-onset androgenetic alopecia and their unexpected association with common diseases. (PMID: 22693459) Li R. … Richards J.B. (PLoS Genet. 2012) 3
  4. Common variants near TARDBP and EGR2 are associated with susceptibility to Ewing sarcoma. (PMID: 22327514) Postel-Vinay S. … Delattre O. (Nat. Genet. 2012) 48
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4

Products for C1orf127 Gene

Sources for C1orf127 Gene

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