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Aliases for C1orf123 Gene

Aliases for C1orf123 Gene

  • Chromosome 1 Open Reading Frame 123 2 3 5

External Ids for C1orf123 Gene

Previous GeneCards Identifiers for C1orf123 Gene

  • GC01M053392
  • GC01M053452
  • GC01M053679
  • GC01M051795

Summaries for C1orf123 Gene

GeneCards Summary for C1orf123 Gene

C1orf123 (Chromosome 1 Open Reading Frame 123) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C1orf123 Gene

Genomics for C1orf123 Gene

Regulatory Elements for C1orf123 Gene

Promoters for C1orf123 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around C1orf123 on UCSC Golden Path with GeneCards custom track

Genomic Location for C1orf123 Gene

Chromosome:
1
Start:
53,214,099 bp from pter
End:
53,220,639 bp from pter
Size:
6,541 bases
Orientation:
Minus strand

Genomic View for C1orf123 Gene

Genes around C1orf123 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C1orf123 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C1orf123 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C1orf123 Gene

Proteins for C1orf123 Gene

  • Protein details for C1orf123 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9NWV4-CA123_HUMAN
    Recommended name:
    UPF0587 protein C1orf123
    Protein Accession:
    Q9NWV4

    Protein attributes for C1orf123 Gene

    Size:
    160 amino acids
    Molecular mass:
    18048 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C1orf123 Gene

Proteomics data for C1orf123 Gene at MOPED

Post-translational modifications for C1orf123 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C1orf123 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C1orf123 Gene

Domains & Families for C1orf123 Gene

Protein Domains for C1orf123 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for C1orf123 Gene

Graphical View of Domain Structure for InterPro Entry

Q9NWV4

UniProtKB/Swiss-Prot:

CA123_HUMAN :
  • Belongs to the UPF0587 family.
Family:
  • Belongs to the UPF0587 family.
genes like me logo Genes that share domains with C1orf123: view

No data available for Gene Families for C1orf123 Gene

Function for C1orf123 Gene

genes like me logo Genes that share phenotypes with C1orf123: view

Animal Model Products

CRISPR Products

miRNA for C1orf123 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C1orf123 Gene

Localization for C1orf123 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for C1orf123 Gene COMPARTMENTS Subcellular localization image for C1orf123 gene
Compartment Confidence
extracellular 5
cytosol 3
nucleus 1
plasma membrane 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C1orf123 Gene

Pathways & Interactions for C1orf123 Gene

SuperPathways for C1orf123 Gene

No Data Available

Interacting Proteins for C1orf123 Gene

Gene Ontology (GO) - Biological Process for C1orf123 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C1orf123 Gene

Drugs & Compounds for C1orf123 Gene

No Compound Related Data Available

Transcripts for C1orf123 Gene

Unigene Clusters for C1orf123 Gene

Chromosome 1 open reading frame 123:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for C1orf123 Gene

ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7 ^ 8 ^ 9a · 9b · 9c · 9d · 9e · 9f
SP1: - - -
SP2: - - -
SP3: - - - -
SP4: - -
SP5: -
SP6:
SP7: -

Relevant External Links for C1orf123 Gene

GeneLoc Exon Structure for
C1orf123
ECgene alternative splicing isoforms for
C1orf123

Expression for C1orf123 Gene

mRNA expression in normal human tissues for C1orf123 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for C1orf123 Gene



SOURCE GeneReport for Unigene cluster for C1orf123 Gene Hs.525391

genes like me logo Genes that share expression patterns with C1orf123: view

Protein tissue co-expression partners for C1orf123 Gene

- Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA differential expression in normal tissues , Protein differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for C1orf123 Gene

Orthologs for C1orf123 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for C1orf123 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia -- 36
  • 100 (a)
OneToMany
-- 36
  • 99 (a)
OneToMany
C1H1orf123 35
  • 100 (n)
  • 100 (a)
cow
(Bos Taurus)
Mammalia C3H1orf123 36
  • 96 (a)
OneToOne
C3H1orf123 35
  • 91.67 (n)
  • 95.62 (a)
dog
(Canis familiaris)
Mammalia C5H1orf123 35
  • 91.25 (n)
  • 95 (a)
C1orf123 36
  • 75 (a)
OneToOne
mouse
(Mus musculus)
Mammalia 0610037L13Rik 16
0610037L13Rik 35
  • 91.56 (n)
  • 94.94 (a)
0610037L13Rik 36
  • 77 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia C1orf123 36
  • 54 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia C1orf123 36
  • 83 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia RGD1559786 35
  • 90.21 (n)
  • 95.62 (a)
chicken
(Gallus gallus)
Aves C8H1ORF123 35
  • 79.58 (n)
  • 83.75 (a)
C1orf123 36
  • 84 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia C1orf123 36
  • 85 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100497300 35
  • 75 (n)
  • 80.62 (a)
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.10583 35
zebrafish
(Danio rerio)
Actinopterygii Dr.23495 35
si:ch211-284b7.3 35
  • 74.79 (n)
  • 81.87 (a)
C2H1orf123 36
  • 82 (a)
OneToOne
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP003919 35
  • 54.09 (n)
  • 44.65 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG4646 35
  • 55.49 (n)
  • 46.84 (a)
CG4646 36
  • 44 (a)
OneToOne
worm
(Caenorhabditis elegans)
Secernentea F46B6.12 36
  • 46 (a)
OneToOne
F46B6.12 35
  • 55.27 (n)
  • 48.73 (a)
A. gosspyii yeast
(Ashbya gossypii)
Saccharomycetes AGOS_AGL238W 35
  • 43.61 (n)
  • 30.08 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes YCR090C 35
  • 43.01 (n)
  • 27.1 (a)
-- 38
K. lactis yeast
(Kluyveromyces lactis)
Saccharomycetes KLLA0F10153g 35
  • 46 (n)
  • 34.67 (a)
thale cress
(Arabidopsis thaliana)
eudicotyledons AT4G32930 35
  • 50.85 (n)
  • 38.46 (a)
rice
(Oryza sativa)
Liliopsida Os01g0565600 35
  • 52.69 (n)
  • 41.94 (a)
bread mold
(Neurospora crassa)
Ascomycetes NCU08505 35
  • 51.9 (n)
  • 42.95 (a)
fission yeast
(Schizosaccharomyces pombe)
Schizosaccharomycetes SPBC2D10.03c 35
  • 49.54 (n)
  • 40.41 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 48 (a)
OneToOne
Species with no ortholog for C1orf123:
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for C1orf123 Gene

ENSEMBL:
Gene Tree for C1orf123 (if available)
TreeFam:
Gene Tree for C1orf123 (if available)

Paralogs for C1orf123 Gene

Pseudogenes.org Pseudogenes for C1orf123 Gene

genes like me logo Genes that share paralogs with C1orf123: view

No data available for Paralogs for C1orf123 Gene

Variants for C1orf123 Gene

Sequence variations from dbSNP and Humsavar for C1orf123 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs436887 -- 53,218,853(+) TTGGG(C/G/T)GGGGA intron-variant
rs1134688 -- 53,216,027(-) GAGTC(A/C)GGGAC reference, synonymous-codon
rs1679913 -- 53,220,711(+) CGCGC(C/G)GCTGC upstream-variant-2KB
rs11546995 -- 53,218,444(-) AGAAG(A/T)GCAAG reference, missense
rs12567834 -- 53,217,355(+) CCATG(C/T)AGTAA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C1orf123 Gene

Variant ID Type Subtype PubMed ID
esv2422213 CNV Duplication 17116639
nsv829871 CNV Loss 17160897

Variation tolerance for C1orf123 Gene

Residual Variation Intolerance Score: 33.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.74; 15.59% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C1orf123 Gene

HapMap Linkage Disequilibrium report
C1orf123

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C1orf123 Gene

Disorders for C1orf123 Gene

Relevant External Links for C1orf123

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C1orf123

No disorders were found for C1orf123 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C1orf123 Gene

Publications for C1orf123 Gene

  1. Integrated genomics and proteomics of the Torpedo californica electric organ: concordance with the mammalian neuromuscular junction. (PMID: 21798097) Mate S.E. … Hoffman E.P. (Skelet Muscle 2011) 2 3 67
  2. Panorama of ancient metazoan macromolecular complexes. (PMID: 26344197) Wan C. … Emili A. (Nature 2015) 3
  3. Proteomic analysis of podocyte exosome-enriched fraction from normal human urine. (PMID: 23376485) Prunotto M. … Moll S. (J Proteomics 2013) 3
  4. A directed protein interaction network for investigating intracellular signal transduction. (PMID: 21900206) Vinayagam A. … Wanker E.E. (Sci Signal 2011) 3
  5. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P. … Vidal M. (Genomics 2007) 3

Products for C1orf123 Gene

Sources for C1orf123 Gene

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