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Aliases for C1orf122 Gene

Aliases for C1orf122 Gene

  • Chromosome 1 Open Reading Frame 122 2 3 5
  • Uncharacterized Protein C1orf122 3
  • Protein ALAESM 4
  • ALAESM 3

External Ids for C1orf122 Gene

Previous GeneCards Identifiers for C1orf122 Gene

  • GC01P037944
  • GC01P038045
  • GC01P038272
  • GC01P036391

Summaries for C1orf122 Gene

GeneCards Summary for C1orf122 Gene

C1orf122 (Chromosome 1 Open Reading Frame 122) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C1orf122 Gene

Genomics for C1orf122 Gene

Regulatory Elements for C1orf122 Gene

Enhancers for C1orf122 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01F037842 0.3 FANTOM5 11.4 +35.8 35809 0.2 FOSL1 TFDP1 ZBTB33 NR2C2 ZC3H12A YRDC C1orf122 ENSG00000233728 MTF1 FHL3 SNIP1 RPS2P13
GH01F037847 0.7 Ensembl 11.2 +40.9 40922 0.2 ARID1B SMAD5 IKZF1 YRDC C1orf122 ENSG00000233728 C1orf109 CDCA8 RPS2P13 MTF1
GH01F037844 1.3 FANTOM5 Ensembl 11.2 +39.2 39222 2.8 BCOR HDAC1 IRF2 ESRRA CREB3L1 NFRKB ZMYM3 ZNF316 GATA2 STAT2 MTF1 ZC3H12A INPP5B YRDC C1orf122 ENSG00000233728 C1orf109 CDCA8 FHL3 SNIP1
GH01F037849 1.2 FANTOM5 Ensembl ENCODE 10.8 +44.8 44822 4.0 HLF CEBPB ZNF316 ZNF366 GATA2 HMBOX1 ZNF24 NR2F6 MAFK EMSY MTF1 INPP5B ZC3H12A YRDC C1orf122 ENSG00000233728 SNIP1 RPS2P13
GH01F038008 0.5 Ensembl ENCODE 10.2 +205.9 205931 9.3 CREB3L1 MLX ZFP64 DMAP1 YY1 SLC30A9 ZNF143 ZNF263 SP3 NFYC INPP5B CDCA8 SF3A3 RNU6-510P ENSG00000230955 MTF1 YRDC C1orf122 GNL2 C1orf109
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around C1orf122 on UCSC Golden Path with GeneCards custom track

Promoters for C1orf122 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000534695 1221 2001 PKNOX1 ATF1 CREB3L1 WRNIP1 ARID4B SIN3A DMAP1 ZNF48 ETS1 YY1

Genomic Location for C1orf122 Gene

37,806,979 bp from pter
37,809,454 bp from pter
2,476 bases
Plus strand

Genomic View for C1orf122 Gene

Genes around C1orf122 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C1orf122 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C1orf122 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C1orf122 Gene

Proteins for C1orf122 Gene

  • Protein details for C1orf122 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized protein C1orf122
    Protein Accession:
    Secondary Accessions:
    • A2RQF4
    • E9PQ13
    • Q56A71

    Protein attributes for C1orf122 Gene

    110 amino acids
    Molecular mass:
    11471 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAH57819.1; Type=Erroneous translation; Note=Wrong choice of CDS.; Evidence={ECO:0000305}; Sequence=BAC86950.1; Type=Erroneous translation; Note=Wrong choice of CDS.; Evidence={ECO:0000305}; Sequence=CAH70085.1; Type=Erroneous translation; Note=Wrong choice of CDS.; Evidence={ECO:0000305};

    Alternative splice isoforms for C1orf122 Gene


neXtProt entry for C1orf122 Gene

Post-translational modifications for C1orf122 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C1orf122 Gene

No data available for DME Specific Peptides for C1orf122 Gene

Domains & Families for C1orf122 Gene

Protein Domains for C1orf122 Gene


Suggested Antigen Peptide Sequences for C1orf122 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C1orf122: view

No data available for Gene Families and UniProtKB/Swiss-Prot for C1orf122 Gene

Function for C1orf122 Gene

Phenotypes for C1orf122 Gene

genes like me logo Genes that share phenotypes with C1orf122: view

Animal Model Products

miRNA for C1orf122 Gene

miRTarBase miRNAs that target C1orf122

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C1orf122 Gene

Localization for C1orf122 Gene

Subcellular locations from

Jensen Localization Image for C1orf122 Gene COMPARTMENTS Subcellular localization image for C1orf122 gene
Compartment Confidence
extracellular 3
nucleus 3
cytosol 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C1orf122 Gene

Pathways & Interactions for C1orf122 Gene

SuperPathways for C1orf122 Gene

No Data Available

Interacting Proteins for C1orf122 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
Selected Interacting proteins: ENSP00000362133 Q6ZSJ8-CA122_HUMAN for C1orf122 Gene via STRING IID

Gene Ontology (GO) - Biological Process for C1orf122 Gene


No data available for Pathways by source and SIGNOR curated interactions for C1orf122 Gene

Transcripts for C1orf122 Gene

Unigene Clusters for C1orf122 Gene

Chromosome 1 open reading frame 122:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C1orf122 Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3a · 3b
SP1: -

Relevant External Links for C1orf122 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C1orf122 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for C1orf122 Gene

Protein differential expression in normal tissues from HIPED for C1orf122 Gene

This gene is overexpressed in Bone marrow stromal cell (17.3), Fetal testis (11.2), Testis (6.9), Seminal vesicle (6.3), and Prostate (6.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for C1orf122 Gene

Protein tissue co-expression partners for C1orf122 Gene

NURSA nuclear receptor signaling pathways regulating expression of C1orf122 Gene:


SOURCE GeneReport for Unigene cluster for C1orf122 Gene:

genes like me logo Genes that share expression patterns with C1orf122: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for C1orf122 Gene

Orthologs for C1orf122 Gene

This gene was present in the common ancestor of mammals.

Orthologs for C1orf122 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia C1H1orf122 34
  • 99.7 (n)
(Bos Taurus)
Mammalia C1orf122 35
  • 96 (a)
C3H1orf122 34
  • 95.45 (n)
(Canis familiaris)
Mammalia C1orf122 35
  • 95 (a)
C15H1orf122 34
  • 92.12 (n)
(Rattus norvegicus)
Mammalia RGD1559909 34
  • 90.83 (n)
(Mus musculus)
Mammalia 1110065P20Rik 35
  • 87 (a)
Species where no ortholog for C1orf122 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C1orf122 Gene

Gene Tree for C1orf122 (if available)
Gene Tree for C1orf122 (if available)

Paralogs for C1orf122 Gene

No data available for Paralogs for C1orf122 Gene

Variants for C1orf122 Gene

Sequence variations from dbSNP and Humsavar for C1orf122 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs1046387 -- 37,808,679(+) CCTGC(A/G)AGGAG upstream-variant-2KB, reference, missense, utr-variant-5-prime
rs1046484 -- 37,809,338(+) GTGGT(C/T)TGGCC downstream-variant-500B, upstream-variant-2KB, utr-variant-3-prime
rs1046520 -- 37,809,405(+) GCCCC(A/C)CAAAA downstream-variant-500B, upstream-variant-2KB, utr-variant-3-prime
rs111673512 -- 37,808,976(+) CAACT(A/G)GAACG upstream-variant-2KB, splice-acceptor-variant
rs111863822 -- 37,806,328(+) CCCAA(A/G)TAGCT intron-variant, upstream-variant-2KB

Variation tolerance for C1orf122 Gene

Gene Damage Index Score: 0.38; 8.35% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C1orf122 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for C1orf122 Gene

Disorders for C1orf122 Gene

Relevant External Links for C1orf122

Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for C1orf122 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C1orf122 Gene

Publications for C1orf122 Gene

  1. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4 64
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3 64
  5. Novel interactive partners of neuroligin 3: new aspects for pathogenesis of autism. (PMID: 25464930) Shen C. … Zhong N. (J. Mol. Neurosci. 2015) 3 64

Products for C1orf122 Gene

Sources for C1orf122 Gene

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