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Aliases for C1orf122 Gene

Aliases for C1orf122 Gene

  • Chromosome 1 Open Reading Frame 122 2 3 5
  • Uncharacterized Protein C1orf122 3
  • Protein ALAESM 4
  • ALAESM 3

External Ids for C1orf122 Gene

Previous GeneCards Identifiers for C1orf122 Gene

  • GC01P037944
  • GC01P038045
  • GC01P038272
  • GC01P036391

Summaries for C1orf122 Gene

GeneCards Summary for C1orf122 Gene

C1orf122 (Chromosome 1 Open Reading Frame 122) is a Protein Coding gene.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C1orf122 Gene

Genomics for C1orf122 Gene

Regulatory Elements for C1orf122 Gene

Enhancers for C1orf122 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01G038008 1.7 Ensembl ENCODE dbSUPER 10.2 +205.9 205931 9.3 MLX CREB3L1 ZFP64 DMAP1 YY1 SLC30A9 ZNF143 ZNF263 SP3 NFYC INPP5B RNU6-510P SF3A3 ENSG00000230955 MTF1 YRDC C1orf122 C1orf109 CDCA8 UTP11
GH01G037850 1.6 FANTOM5 Ensembl ENCODE dbSUPER 10.8 +44.9 44922 3.8 NR2F1 HLF CEBPB CEBPG ZNF316 GATA2 ZNF366 NR2C1 HMBOX1 NR2F6 MTF1 INPP5B ZC3H12A YRDC C1orf122 ENSG00000233728 SNIP1 RPS2P13
GH01G037845 1.2 FANTOM5 Ensembl 11.3 +39.4 39422 2.4 BCOR PKNOX1 ESRRA IRF2 ZMYM3 ZNF316 GATA2 STAT2 TRIM24 NFE2 MTF1 ZC3H12A YRDC C1orf122 ENSG00000233728 C1orf109 CDCA8 FHL3 SNIP1 RPS2P13
GH01G037844 0.9 Ensembl 11.4 +37.7 37722 0.2 HDAC1 CBX3 PKNOX1 TBL1XR1 ARNT CREB3L1 NFRKB TCF12 CREM EGR2 C1orf122 YRDC ENSG00000233728 RPS2P13 MTF1
GH01G038020 1 ENCODE dbSUPER 10.2 +212.1 212145 0.2 CTCF MAX CEBPG RAD21 SMC3 DEK ZNF654 L3MBTL2 ZBTB11 TRIM22 RNU6-510P SF3A3 INPP5B C1orf122 YRDC UTP11 GC01P038029
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around C1orf122 on UCSC Golden Path with GeneCards custom track

Promoters for C1orf122 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000004891 1221 2001 PKNOX1 ARNT CREB3L1 AGO1 WRNIP1 ARID4B SIN3A DMAP1 YY1 SP3

Genomic Location for C1orf122 Gene

Chromosome:
1
Start:
37,806,979 bp from pter
End:
37,809,454 bp from pter
Size:
2,476 bases
Orientation:
Plus strand

Genomic View for C1orf122 Gene

Genes around C1orf122 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C1orf122 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C1orf122 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C1orf122 Gene

Proteins for C1orf122 Gene

  • Protein details for C1orf122 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6ZSJ8-CA122_HUMAN
    Recommended name:
    Uncharacterized protein C1orf122
    Protein Accession:
    Q6ZSJ8
    Secondary Accessions:
    • A2RQF4
    • E9PQ13
    • Q56A71

    Protein attributes for C1orf122 Gene

    Size:
    110 amino acids
    Molecular mass:
    11471 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAH57819.1; Type=Erroneous translation; Note=Wrong choice of CDS.; Evidence={ECO:0000305}; Sequence=BAC86950.1; Type=Erroneous translation; Note=Wrong choice of CDS.; Evidence={ECO:0000305}; Sequence=CAH70085.1; Type=Erroneous translation; Note=Wrong choice of CDS.; Evidence={ECO:0000305};

    Alternative splice isoforms for C1orf122 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for C1orf122 Gene

Post-translational modifications for C1orf122 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C1orf122 Gene

No data available for DME Specific Peptides for C1orf122 Gene

Domains & Families for C1orf122 Gene

Protein Domains for C1orf122 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for C1orf122 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C1orf122: view

No data available for Gene Families and UniProtKB/Swiss-Prot for C1orf122 Gene

Function for C1orf122 Gene

Phenotypes for C1orf122 Gene

genes like me logo Genes that share phenotypes with C1orf122: view

Animal Model Products

CRISPR Products

miRNA for C1orf122 Gene

miRTarBase miRNAs that target C1orf122

Inhibitory RNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C1orf122 Gene

Localization for C1orf122 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C1orf122 gene
Compartment Confidence
extracellular 3
nucleus 3
cytosol 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C1orf122 Gene

Pathways & Interactions for C1orf122 Gene

SuperPathways for C1orf122 Gene

No Data Available

Interacting Proteins for C1orf122 Gene

Gene Ontology (GO) - Biological Process for C1orf122 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C1orf122 Gene

Drugs & Compounds for C1orf122 Gene

No Compound Related Data Available

Transcripts for C1orf122 Gene

Unigene Clusters for C1orf122 Gene

Chromosome 1 open reading frame 122:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for C1orf122 Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3a · 3b
SP1: -
SP2:
SP3:

Relevant External Links for C1orf122 Gene

GeneLoc Exon Structure for
C1orf122
ECgene alternative splicing isoforms for
C1orf122

Expression for C1orf122 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for C1orf122 Gene

Protein differential expression in normal tissues from HIPED for C1orf122 Gene

This gene is overexpressed in Bone marrow stromal cell (17.3), Fetal testis (11.2), Testis (6.9), Seminal vesicle (6.3), and Prostate (6.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for C1orf122 Gene



Protein tissue co-expression partners for C1orf122 Gene

NURSA nuclear receptor signaling pathways regulating expression of C1orf122 Gene:

C1orf122

SOURCE GeneReport for Unigene cluster for C1orf122 Gene:

Hs.532749

Evidence on tissue expression from TISSUES for C1orf122 Gene

  • Nervous system(3.3)
  • Pancreas(2.1)
genes like me logo Genes that share expression patterns with C1orf122: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for C1orf122 Gene

Orthologs for C1orf122 Gene

This gene was present in the common ancestor of mammals.

Orthologs for C1orf122 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C1H1orf122 34
  • 99.7 (n)
cow
(Bos Taurus)
Mammalia C1orf122 35
  • 96 (a)
OneToOne
C3H1orf122 34
  • 95.45 (n)
dog
(Canis familiaris)
Mammalia C1orf122 35
  • 95 (a)
OneToOne
C15H1orf122 34
  • 92.12 (n)
rat
(Rattus norvegicus)
Mammalia RGD1559909 34
  • 90.83 (n)
mouse
(Mus musculus)
Mammalia 1110065P20Rik 35
  • 87 (a)
OneToOne
Species where no ortholog for C1orf122 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C1orf122 Gene

ENSEMBL:
Gene Tree for C1orf122 (if available)
TreeFam:
Gene Tree for C1orf122 (if available)

Paralogs for C1orf122 Gene

No data available for Paralogs for C1orf122 Gene

Variants for C1orf122 Gene

Sequence variations from dbSNP and Humsavar for C1orf122 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs1001173441 -- 37,806,473(+) CTGGG(C/G)TCACA intron-variant, upstream-variant-2KB
rs1001204513 -- 37,806,668(+) TTTGA(A/G)ATAAA intron-variant, upstream-variant-2KB
rs1003104554 -- 37,808,586(+) GGCCA(C/T)CCCCA upstream-variant-2KB, reference, missense, utr-variant-5-prime
rs1003420581 -- 37,809,040(+) TTTCC(A/G)AAGGA upstream-variant-2KB, reference, synonymous-codon
rs1003472677 -- 37,809,824(+) TGGAA(A/G)TCCGT intron-variant, upstream-variant-2KB, utr-variant-3-prime

Variation tolerance for C1orf122 Gene

Gene Damage Index Score: 0.38; 8.35% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C1orf122 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
C1orf122

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for C1orf122 Gene

Disorders for C1orf122 Gene

Relevant External Links for C1orf122

Human Genome Epidemiology (HuGE) Navigator
C1orf122
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C1orf122

No disorders were found for C1orf122 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C1orf122 Gene

Publications for C1orf122 Gene

  1. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4 64
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3 64
  5. Novel interactive partners of neuroligin 3: new aspects for pathogenesis of autism. (PMID: 25464930) Shen C. … Zhong N. (J. Mol. Neurosci. 2015) 3 64

Products for C1orf122 Gene

Sources for C1orf122 Gene

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