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Aliases for C1orf122 Gene

Aliases for C1orf122 Gene

  • Chromosome 1 Open Reading Frame 122 2 3 5
  • Protein ALAESM 4
  • ALAESM 3

External Ids for C1orf122 Gene

Previous GeneCards Identifiers for C1orf122 Gene

  • GC01P037944
  • GC01P038045
  • GC01P038272
  • GC01P036391

Summaries for C1orf122 Gene

GeneCards Summary for C1orf122 Gene

C1orf122 (Chromosome 1 Open Reading Frame 122) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C1orf122 Gene

Genomics for C1orf122 Gene

Regulatory Elements for C1orf122 Gene

Promoters for C1orf122 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around C1orf122 on UCSC Golden Path with GeneCards custom track

Genomic Location for C1orf122 Gene

Chromosome:
1
Start:
37,806,979 bp from pter
End:
37,809,454 bp from pter
Size:
2,476 bases
Orientation:
Plus strand

Genomic View for C1orf122 Gene

Genes around C1orf122 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C1orf122 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C1orf122 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C1orf122 Gene

Proteins for C1orf122 Gene

  • Protein details for C1orf122 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6ZSJ8-CA122_HUMAN
    Recommended name:
    Uncharacterized protein C1orf122
    Protein Accession:
    Q6ZSJ8
    Secondary Accessions:
    • A2RQF4
    • E9PQ13
    • Q56A71

    Protein attributes for C1orf122 Gene

    Size:
    110 amino acids
    Molecular mass:
    11471 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAH57819.1; Type=Erroneous translation; Note=Wrong choice of CDS.; Evidence={ECO:0000305}; Sequence=BAC86950.1; Type=Erroneous translation; Note=Wrong choice of CDS.; Evidence={ECO:0000305}; Sequence=CAH70085.1; Type=Erroneous translation; Note=Wrong choice of CDS.; Evidence={ECO:0000305};

    Alternative splice isoforms for C1orf122 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for C1orf122 Gene

Proteomics data for C1orf122 Gene at MOPED

Post-translational modifications for C1orf122 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C1orf122 Gene

No data available for DME Specific Peptides for C1orf122 Gene

Domains & Families for C1orf122 Gene

Protein Domains for C1orf122 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for C1orf122 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C1orf122: view

No data available for Gene Families and UniProtKB/Swiss-Prot for C1orf122 Gene

Function for C1orf122 Gene

Phenotypes for C1orf122 Gene

genes like me logo Genes that share phenotypes with C1orf122: view

Animal Model Products

CRISPR Products

miRNA for C1orf122 Gene

miRTarBase miRNAs that target C1orf122

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C1orf122 Gene

Localization for C1orf122 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for C1orf122 Gene COMPARTMENTS Subcellular localization image for C1orf122 gene
Compartment Confidence
extracellular 3
nucleus 3
cytosol 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C1orf122 Gene

Pathways & Interactions for C1orf122 Gene

SuperPathways for C1orf122 Gene

No Data Available

Interacting Proteins for C1orf122 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000362133%0d%0a9606.ENSP00000368831%0d%0a
Selected Interacting proteins: ENSP00000362133 for C1orf122 Gene via STRING

Symbol External ID(s) Details
SNX2

Gene Ontology (GO) - Biological Process for C1orf122 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C1orf122 Gene

Drugs & Compounds for C1orf122 Gene

No Compound Related Data Available

Transcripts for C1orf122 Gene

Unigene Clusters for C1orf122 Gene

Chromosome 1 open reading frame 122:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for C1orf122 Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3a · 3b
SP1: -
SP2:
SP3:

Relevant External Links for C1orf122 Gene

GeneLoc Exon Structure for
C1orf122
ECgene alternative splicing isoforms for
C1orf122

Expression for C1orf122 Gene

mRNA expression in normal human tissues for C1orf122 Gene

Protein differential expression in normal tissues from HIPED for C1orf122 Gene

This gene is overexpressed in Bone marrow stromal cell (17.3), Fetal testis (11.2), Testis (6.9), Seminal vesicle (6.3), and Prostate (6.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MOPED, and MaxQB for C1orf122 Gene



SOURCE GeneReport for Unigene cluster for C1orf122 Gene Hs.532749

genes like me logo Genes that share expression patterns with C1orf122: view

Protein tissue co-expression partners for C1orf122 Gene

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for C1orf122 Gene

Orthologs for C1orf122 Gene

This gene was present in the common ancestor of mammals.

Orthologs for C1orf122 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia C3H1orf122 35
  • 95.45 (n)
  • 96.36 (a)
C1orf122 36
  • 96 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C15H1orf122 35
  • 92.12 (n)
  • 95.45 (a)
C1orf122 36
  • 95 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia C1H1orf122 35
  • 99.7 (n)
  • 100 (a)
rat
(Rattus norvegicus)
Mammalia RGD1559909 35
  • 90.83 (n)
  • 91.74 (a)
mouse
(Mus musculus)
Mammalia 1110065P20Rik 36
  • 87 (a)
OneToOne
Species with no ortholog for C1orf122:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C1orf122 Gene

ENSEMBL:
Gene Tree for C1orf122 (if available)
TreeFam:
Gene Tree for C1orf122 (if available)

Paralogs for C1orf122 Gene

No data available for Paralogs for C1orf122 Gene

Variants for C1orf122 Gene

Structural Variations from Database of Genomic Variants (DGV) for C1orf122 Gene

Variant ID Type Subtype PubMed ID
nsv871810 CNV Loss 21882294
nsv870730 CNV Gain 21882294

Variation tolerance for C1orf122 Gene

Gene Damage Index Score: 0.38; 8.35% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C1orf122 Gene

HapMap Linkage Disequilibrium report
C1orf122

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations from dbSNP and Humsavar for C1orf122 Gene

Disorders for C1orf122 Gene

Relevant External Links for C1orf122

Human Genome Epidemiology (HuGE) Navigator
C1orf122
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C1orf122

No disorders were found for C1orf122 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C1orf122 Gene

Publications for C1orf122 Gene

  1. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4 67
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  4. Toward an understanding of the protein interaction network of the human liver. (PMID: 21988832) Wang J. … Yang X. (Mol. Syst. Biol. 2011) 3
  5. Association of genetic variants with chronic kidney disease in individuals with different lipid profiles. (PMID: 19578796) Yoshida T. … Yamada Y. (Int. J. Mol. Med. 2009) 3

Products for C1orf122 Gene

Sources for C1orf122 Gene

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