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Aliases for C1orf122 Gene

Aliases for C1orf122 Gene

  • Chromosome 1 Open Reading Frame 122 2 3 5
  • Uncharacterized Protein C1orf122 3
  • Protein ALAESM 4
  • ALAESM 3

External Ids for C1orf122 Gene

Previous GeneCards Identifiers for C1orf122 Gene

  • GC01P037944
  • GC01P038045
  • GC01P038272
  • GC01P036391

Summaries for C1orf122 Gene

GeneCards Summary for C1orf122 Gene

C1orf122 (Chromosome 1 Open Reading Frame 122) is a Protein Coding gene.

Additional gene information for C1orf122 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C1orf122 Gene

Genomics for C1orf122 Gene

Regulatory Elements for C1orf122 Gene

Enhancers for C1orf122 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01H038008 1.7 Ensembl ENCODE dbSUPER 10.2 +205.9 205931 9.3 MLX ZFP64 DMAP1 YY1 SLC30A9 ZNF143 SP3 NFYC MEF2D ZNF610 SF3A3 C1orf109 INPP5B SNIP1 RNU6-510P RSPO1 ENSG00000230955 MTF1 YRDC C1orf122
GH01H037850 1.6 FANTOM5 Ensembl ENCODE dbSUPER 10.8 +44.9 44922 3.8 SOX6 HLF CEBPB CEBPG ZNF316 GATA2 ZNF366 NR2C1 HMBOX1 ZNF24 MTF1 INPP5B ZC3H12A YRDC C1orf122 ENSG00000233728 SNIP1 RPS2P13
GH01H037845 1.2 FANTOM5 Ensembl 11.3 +39.4 39422 2.4 PKNOX1 IRF2 ZNF316 GATA2 STAT2 TRIM24 NFE2 IKZF2 MTA2 CEBPB MTF1 ZC3H12A YRDC C1orf122 ENSG00000233728 C1orf109 CDCA8 FHL3 SNIP1 RPS2P13
GH01H038020 1 ENCODE dbSUPER 10.2 +212.1 212145 0.2 CTCF MAX CEBPG RAD21 SMC3 ZNF143 DEK ZNF654 L3MBTL2 ZBTB11 RNU6-510P SF3A3 INPP5B C1orf122 YRDC UTP11 GC01P038029
GH01H038018 0.7 dbSUPER 10.2 +211.8 211775 0.5 CTCF MAX CEBPG RAD21 ZNF143 SMC3 DEK ZNF654 L3MBTL2 ZBTB11 RNU6-510P SF3A3 INPP5B C1orf122 YRDC UTP11 GC01P038029
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around C1orf122 on UCSC Golden Path with GeneCards custom track

Promoters for C1orf122 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000004891 1221 2001 PKNOX1 ATF1 ARNT ARID4B SIN3A DMAP1 YY1 ETS1 GLIS2 ELK1

Genomic Locations for C1orf122 Gene

Genomic Locations for C1orf122 Gene
chr1:37,806,979-37,809,454
(GRCh38/hg38)
Size:
2,476 bases
Orientation:
Plus strand
chr1:38,272,651-38,275,126
(GRCh37/hg19)

Genomic View for C1orf122 Gene

Genes around C1orf122 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C1orf122 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C1orf122 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C1orf122 Gene

Proteins for C1orf122 Gene

  • Protein details for C1orf122 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6ZSJ8-CA122_HUMAN
    Recommended name:
    Uncharacterized protein C1orf122
    Protein Accession:
    Q6ZSJ8
    Secondary Accessions:
    • A2RQF4
    • E9PQ13
    • Q56A71

    Protein attributes for C1orf122 Gene

    Size:
    110 amino acids
    Molecular mass:
    11471 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAH57819.1; Type=Erroneous translation; Note=Wrong choice of CDS.; Evidence={ECO:0000305}; Sequence=BAC86950.1; Type=Erroneous translation; Note=Wrong choice of CDS.; Evidence={ECO:0000305}; Sequence=CAH70085.1; Type=Erroneous translation; Note=Wrong choice of CDS.; Evidence={ECO:0000305};

    Alternative splice isoforms for C1orf122 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for C1orf122 Gene

Post-translational modifications for C1orf122 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C1orf122 Gene

No data available for DME Specific Peptides for C1orf122 Gene

Domains & Families for C1orf122 Gene

Gene Families for C1orf122 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for C1orf122 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for C1orf122 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C1orf122: view

No data available for UniProtKB/Swiss-Prot for C1orf122 Gene

Function for C1orf122 Gene

Phenotypes From GWAS Catalog for C1orf122 Gene

Phenotypes for C1orf122 Gene

genes like me logo Genes that share phenotypes with C1orf122: view

miRNA for C1orf122 Gene

miRTarBase miRNAs that target C1orf122

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C1orf122 Gene

Localization for C1orf122 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C1orf122 gene
Compartment Confidence
extracellular 3
nucleus 3
cytosol 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for C1orf122 Gene

Pathways & Interactions for C1orf122 Gene

SuperPathways for C1orf122 Gene

No Data Available

Interacting Proteins for C1orf122 Gene

Gene Ontology (GO) - Biological Process for C1orf122 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C1orf122 Gene

Drugs & Compounds for C1orf122 Gene

No Compound Related Data Available

Transcripts for C1orf122 Gene

Unigene Clusters for C1orf122 Gene

Chromosome 1 open reading frame 122:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for C1orf122 Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3a · 3b
SP1: -
SP2:
SP3:

Relevant External Links for C1orf122 Gene

GeneLoc Exon Structure for
C1orf122
ECgene alternative splicing isoforms for
C1orf122

Expression for C1orf122 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for C1orf122 Gene

Protein differential expression in normal tissues from HIPED for C1orf122 Gene

This gene is overexpressed in Bone marrow stromal cell (17.3), Fetal testis (11.2), Testis (6.9), Seminal vesicle (6.3), and Prostate (6.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for C1orf122 Gene



Protein tissue co-expression partners for C1orf122 Gene

NURSA nuclear receptor signaling pathways regulating expression of C1orf122 Gene:

C1orf122

SOURCE GeneReport for Unigene cluster for C1orf122 Gene:

Hs.532749

Evidence on tissue expression from TISSUES for C1orf122 Gene

  • Nervous system(3.3)
  • Pancreas(2.1)
genes like me logo Genes that share expression patterns with C1orf122: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for C1orf122 Gene

Orthologs for C1orf122 Gene

This gene was present in the common ancestor of mammals.

Orthologs for C1orf122 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C1H1orf122 33
  • 99.7 (n)
cow
(Bos Taurus)
Mammalia C1orf122 34
  • 96 (a)
OneToOne
C3H1orf122 33
  • 95.45 (n)
dog
(Canis familiaris)
Mammalia C1orf122 34
  • 95 (a)
OneToOne
C15H1orf122 33
  • 92.12 (n)
rat
(Rattus norvegicus)
Mammalia RGD1559909 33
  • 90.83 (n)
mouse
(Mus musculus)
Mammalia 1110065P20Rik 34
  • 87 (a)
OneToOne
Species where no ortholog for C1orf122 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C1orf122 Gene

ENSEMBL:
Gene Tree for C1orf122 (if available)
TreeFam:
Gene Tree for C1orf122 (if available)

Paralogs for C1orf122 Gene

No data available for Paralogs for C1orf122 Gene

Variants for C1orf122 Gene

Sequence variations from dbSNP and Humsavar for C1orf122 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs1001173441 -- 37,806,473(+) CTGGG(C/G)TCACA intron-variant, upstream-variant-2KB
rs1001204513 -- 37,806,668(+) TTTGA(A/G)ATAAA intron-variant, upstream-variant-2KB
rs1003104554 -- 37,808,586(+) GGCCA(C/T)CCCCA upstream-variant-2KB, reference, missense, utr-variant-5-prime
rs1003420581 -- 37,809,040(+) TTTCC(A/G)AAGGA upstream-variant-2KB, reference, synonymous-codon
rs1003472677 -- 37,809,824(+) TGGAA(A/G)TCCGT intron-variant, upstream-variant-2KB, utr-variant-3-prime

Variation tolerance for C1orf122 Gene

Gene Damage Index Score: 0.38; 8.35% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C1orf122 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
C1orf122

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for C1orf122 Gene

Disorders for C1orf122 Gene

Relevant External Links for C1orf122

Human Genome Epidemiology (HuGE) Navigator
C1orf122
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C1orf122

No disorders were found for C1orf122 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C1orf122 Gene

Publications for C1orf122 Gene

  1. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory SG … Prigmore E (Nature 2006) 3 4 60
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 60
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 60
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 2 3 60
  5. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 60

Products for C1orf122 Gene

Sources for C1orf122 Gene

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