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Aliases for C1orf115 Gene

Aliases for C1orf115 Gene

  • Chromosome 1 Open Reading Frame 115 2 3 5

External Ids for C1orf115 Gene

Previous GeneCards Identifiers for C1orf115 Gene

  • GC01P217252
  • GC01P218929
  • GC01P220863
  • GC01P191538

Summaries for C1orf115 Gene

GeneCards Summary for C1orf115 Gene

C1orf115 (Chromosome 1 Open Reading Frame 115) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C1orf115 Gene

Genomics for C1orf115 Gene

Regulatory Elements for C1orf115 Gene

Promoters for C1orf115 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around C1orf115 on UCSC Golden Path with GeneCards custom track

Genomic Location for C1orf115 Gene

Chromosome:
1
Start:
220,689,845 bp from pter
End:
220,699,157 bp from pter
Size:
9,313 bases
Orientation:
Plus strand

Genomic View for C1orf115 Gene

Genes around C1orf115 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C1orf115 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C1orf115 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C1orf115 Gene

Proteins for C1orf115 Gene

  • Protein details for C1orf115 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9H7X2-CA115_HUMAN
    Recommended name:
    Uncharacterized protein C1orf115
    Protein Accession:
    Q9H7X2
    Secondary Accessions:
    • B3KRN3
    • D3DTB2

    Protein attributes for C1orf115 Gene

    Size:
    142 amino acids
    Molecular mass:
    15517 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C1orf115 Gene

Proteomics data for C1orf115 Gene at MOPED

Post-translational modifications for C1orf115 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C1orf115 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C1orf115 Gene

Domains & Families for C1orf115 Gene

Protein Domains for C1orf115 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C1orf115: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C1orf115 Gene

Function for C1orf115 Gene

Phenotypes for C1orf115 Gene

GenomeRNAi human phenotypes for C1orf115:
genes like me logo Genes that share phenotypes with C1orf115: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C1orf115 Gene

Localization for C1orf115 Gene

Subcellular locations from UniProtKB/Swiss-Prot for C1orf115 Gene

Membrane; Single-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for C1orf115 Gene COMPARTMENTS Subcellular localization image for C1orf115 gene
Compartment Confidence
nucleus 3
mitochondrion 2

No data available for Gene Ontology (GO) - Cellular Components for C1orf115 Gene

Pathways & Interactions for C1orf115 Gene

SuperPathways for C1orf115 Gene

No Data Available

Interacting Proteins for C1orf115 Gene

Gene Ontology (GO) - Biological Process for C1orf115 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C1orf115 Gene

Drugs & Compounds for C1orf115 Gene

No Compound Related Data Available

Transcripts for C1orf115 Gene

mRNA/cDNA for C1orf115 Gene

(1) REFSEQ mRNAs :
(5) Additional mRNA sequences :
(144) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for C1orf115 Gene

Chromosome 1 open reading frame 115:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for C1orf115 Gene

No ASD Table

Relevant External Links for C1orf115 Gene

GeneLoc Exon Structure for
C1orf115
ECgene alternative splicing isoforms for
C1orf115

Expression for C1orf115 Gene

mRNA expression in normal human tissues for C1orf115 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for C1orf115 Gene

This gene is overexpressed in Brain - Cortex (x4.3), Brain - Frontal Cortex (BA9) (x4.2), and Liver (x4.1).

SOURCE GeneReport for Unigene cluster for C1orf115 Gene Hs.519839

genes like me logo Genes that share expression patterns with C1orf115: view

Primer Products

In Situ Assay Products

No data available for Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for C1orf115 Gene

Orthologs for C1orf115 Gene

This gene was present in the common ancestor of mammals.

Orthologs for C1orf115 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia C16H1orf115 35
  • 86.03 (n)
  • 82.35 (a)
C16H1orf115 36
  • 80 (a)
OneToOne
mouse
(Mus musculus)
Mammalia C130074G19Rik 35
  • 76.83 (n)
  • 70.21 (a)
C130074G19Rik 16
C130074G19Rik 36
  • 70 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia C1H1orf115 35
  • 99.06 (n)
  • 99.3 (a)
C1orf115 36
  • 99 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia RGD1310587 35
  • 77.38 (n)
  • 72.14 (a)
dog
(Canis familiaris)
Mammalia C1orf115 36
  • 92 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia C1orf115 36
  • 52 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia C1orf115 36
  • 51 (a)
OneToOne
Species with no ortholog for C1orf115:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C1orf115 Gene

ENSEMBL:
Gene Tree for C1orf115 (if available)
TreeFam:
Gene Tree for C1orf115 (if available)

Paralogs for C1orf115 Gene

No data available for Paralogs for C1orf115 Gene

Variants for C1orf115 Gene

Sequence variations from dbSNP and Humsavar for C1orf115 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs14850 -- 220,699,073(-) CAAGC(A/G)AAAGC utr-variant-3-prime
rs337152 -- 220,699,328(-) GGGGT(C/T)TCTCC downstream-variant-500B
rs337153 -- 220,697,978(-) ATGAG(A/G)TCAAA utr-variant-3-prime
rs337154 -- 220,697,781(-) TCCAA(C/T)GTCCT utr-variant-3-prime
rs337155 -- 220,696,553(-) ATTCT(A/G)CCATC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C1orf115 Gene

Variant ID Type Subtype PubMed ID
nsv468194 CNV Loss 19166990
nsv826742 CNV Loss 20364138

Variation tolerance for C1orf115 Gene

Gene Damage Index Score: 1.02; 20.85% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C1orf115 Gene

HapMap Linkage Disequilibrium report
C1orf115

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C1orf115 Gene

Disorders for C1orf115 Gene

Relevant External Links for C1orf115

Genetic Association Database (GAD)
C1orf115
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C1orf115

No disorders were found for C1orf115 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C1orf115 Gene

Publications for C1orf115 Gene

  1. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4 67
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PMID: 21832049) OlA!h J. … OvA!di J. (J. Biol. Chem. 2011) 3
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3

Products for C1orf115 Gene

Sources for C1orf115 Gene

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