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Aliases for C1orf112 Gene

Aliases for C1orf112 Gene

  • Chromosome 1 Open Reading Frame 112 2 3 5

External Ids for C1orf112 Gene

Previous GeneCards Identifiers for C1orf112 Gene

  • GC01P166496
  • GC01P168030
  • GC01P169631
  • GC01P140986

Summaries for C1orf112 Gene

GeneCards Summary for C1orf112 Gene

C1orf112 (Chromosome 1 Open Reading Frame 112) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C1orf112 Gene

Genomics for C1orf112 Gene

Regulatory Elements for C1orf112 Gene

Enhancers for C1orf112 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around C1orf112 on UCSC Golden Path with GeneCards custom track

Promoters for C1orf112 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around C1orf112 on UCSC Golden Path with GeneCards custom track

Genomic Location for C1orf112 Gene

169,662,007 bp from pter
169,854,080 bp from pter
192,074 bases
Plus strand

Genomic View for C1orf112 Gene

Genes around C1orf112 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C1orf112 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C1orf112 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C1orf112 Gene

Proteins for C1orf112 Gene

  • Protein details for C1orf112 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized protein C1orf112
    Protein Accession:
    Secondary Accessions:
    • A6NFP1
    • B3KU42
    • Q3KNQ1
    • Q9H8L5
    • Q9NVJ0

    Protein attributes for C1orf112 Gene

    853 amino acids
    Molecular mass:
    96554 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for C1orf112 Gene


neXtProt entry for C1orf112 Gene

Proteomics data for C1orf112 Gene at MOPED

Post-translational modifications for C1orf112 Gene

  • Ubiquitination at Lys 25 and Lys 783
  • Modification sites at PhosphoSitePlus

Other Protein References for C1orf112 Gene

No data available for DME Specific Peptides for C1orf112 Gene

Domains & Families for C1orf112 Gene

Protein Domains for C1orf112 Gene


Suggested Antigen Peptide Sequences for C1orf112 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C1orf112: view

No data available for Gene Families and UniProtKB/Swiss-Prot for C1orf112 Gene

Function for C1orf112 Gene

Phenotypes for C1orf112 Gene

MGI mutant phenotypes for C1orf112:
inferred from 2 alleles
GenomeRNAi human phenotypes for C1orf112:
genes like me logo Genes that share phenotypes with C1orf112: view

Animal Models for C1orf112 Gene

MGI Knock Outs for C1orf112:

Animal Model Products

CRISPR Products

miRNA for C1orf112 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for C1orf112 Gene

Localization for C1orf112 Gene

Subcellular locations from

Jensen Localization Image for C1orf112 Gene COMPARTMENTS Subcellular localization image for C1orf112 gene
Compartment Confidence
mitochondrion 3
nucleus 3
cytosol 2
extracellular 1
peroxisome 1
plasma membrane 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C1orf112 Gene

Pathways & Interactions for C1orf112 Gene

SuperPathways for C1orf112 Gene

No Data Available

Interacting Proteins for C1orf112 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
Selected Interacting proteins: ENSP00000286031 for C1orf112 Gene via STRING

Symbol External ID(s) Details

Gene Ontology (GO) - Biological Process for C1orf112 Gene


No data available for Pathways by source and SIGNOR curated interactions for C1orf112 Gene

Drugs & Compounds for C1orf112 Gene

No Compound Related Data Available

Transcripts for C1orf112 Gene

Unigene Clusters for C1orf112 Gene

Chromosome 1 open reading frame 112:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for C1orf112 Gene

ExUns: 1 ^ 2a · 2b ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7a · 7b · 7c · 7d ^ 8 ^ 9a · 9b ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20 ^
SP2: - -
SP3: - -
SP4: - - - -
SP5: - - -
SP6: - - - - -

ExUns: 21 ^ 22 ^ 23 ^ 24 ^ 25a · 25b

Relevant External Links for C1orf112 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C1orf112 Gene

mRNA expression in normal human tissues for C1orf112 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for C1orf112 Gene

This gene is overexpressed in Bone (62.7) and Heart (6.3).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MOPED, and MaxQB for C1orf112 Gene

SOURCE GeneReport for Unigene cluster for C1orf112 Gene Hs.443551

genes like me logo Genes that share expression patterns with C1orf112: view

Protein tissue co-expression partners for C1orf112 Gene

- Elite partner

Primer Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for C1orf112 Gene

Orthologs for C1orf112 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C1orf112 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia C16H1orf112 35
  • 87.29 (n)
  • 83.71 (a)
C1orf112 36
  • 78 (a)
(Canis familiaris)
Mammalia C7H1orf112 35
  • 87.55 (n)
  • 83.98 (a)
C1orf112 36
  • 79 (a)
(Mus musculus)
Mammalia BC055324 35
  • 81.36 (n)
  • 72.99 (a)
BC055324 16
BC055324 36
  • 68 (a)
(Pan troglodytes)
Mammalia C1H1orf112 35
  • 99.3 (n)
  • 99.18 (a)
C1orf112 36
  • 99 (a)
(Rattus norvegicus)
Mammalia LOC498265 35
  • 81.67 (n)
  • 74.76 (a)
(Monodelphis domestica)
Mammalia C1orf112 36
  • 73 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 67 (a)
-- 36
  • 66 (a)
(Gallus gallus)
Aves C8H1ORF112 35
  • 68.05 (n)
  • 63.04 (a)
C1orf112 36
  • 55 (a)
(Anolis carolinensis)
Reptilia C1orf112 36
  • 49 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia c1orf112 35
  • 59.97 (n)
  • 54.89 (a)
Str.481 35
(Danio rerio)
Actinopterygii si:dkey-97o5.1 35
  • 54.41 (n)
  • 46.59 (a)
C20H1orf112 36
  • 43 (a)
Species with no ortholog for C1orf112:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C1orf112 Gene

Gene Tree for C1orf112 (if available)
Gene Tree for C1orf112 (if available)

Paralogs for C1orf112 Gene

No data available for Paralogs for C1orf112 Gene

Variants for C1orf112 Gene

Sequence variations from dbSNP and Humsavar for C1orf112 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs2272920 - 169,830,739(-) ATGAG(A/C)CACTA nc-transcript-variant, reference, missense
rs725526 -- 169,852,405(+) AATTA(C/G)TATAG intron-variant
rs730083 -- 169,798,280(-) AAAAA(A/G)AGAGA intron-variant
rs2143121 -- 169,845,407(-) TATTT(C/T)AAGAA intron-variant
rs2143122 -- 169,845,392(-) CCACA(A/G)CCACC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C1orf112 Gene

Variant ID Type Subtype PubMed ID
dgv146e1 CNV Complex 17122850
nsv428268 CNV Gain+Loss 18775914
nsv872542 CNV Gain 21882294
esv2719417 CNV Deletion 23290073

Variation tolerance for C1orf112 Gene

Residual Variation Intolerance Score: 10.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 5.22; 69.95% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for C1orf112 Gene

Disorders for C1orf112 Gene

Relevant External Links for C1orf112

Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for C1orf112 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C1orf112 Gene

Publications for C1orf112 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 67
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  4. A human interactome in three quantitative dimensions organized by stoichiometries and abundances. (PMID: 26496610) Hein M.Y. … Mann M. (Cell 2015) 3
  5. GeneFriends: an online co-expression analysis tool to identify novel gene targets for aging and complex diseases. (PMID: 23039964) van Dam S. … de MagalhALes J.P. (BMC Genomics 2012) 3

Products for C1orf112 Gene

Sources for C1orf112 Gene