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Aliases for C1orf112 Gene

Aliases for C1orf112 Gene

  • Chromosome 1 Open Reading Frame 112 2 3

External Ids for C1orf112 Gene

Summaries for C1orf112 Gene

GeneCards Summary for C1orf112 Gene

C1orf112 (Chromosome 1 Open Reading Frame 112) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C1orf112 Gene

Genomics for C1orf112 Gene

Genomic Location for C1orf112 Gene

Start:
169,662,007 bp from pter
End:
169,854,080 bp from pter
Size:
192,074 bases
Orientation:
Plus strand

Genomic View for C1orf112 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for C1orf112 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C1orf112 Gene

Regulatory Elements for C1orf112 Gene

Proteins for C1orf112 Gene

  • Protein details for C1orf112 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9NSG2-CA112_HUMAN
    Recommended name:
    Uncharacterized protein C1orf112
    Protein Accession:
    Q9NSG2
    Secondary Accessions:
    • A6NFP1
    • B3KU42
    • Q3KNQ1
    • Q9H8L5
    • Q9NVJ0

    Protein attributes for C1orf112 Gene

    Size:
    853 amino acids
    Molecular mass:
    96554 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for C1orf112 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for C1orf112 Gene

Proteomics data for C1orf112 Gene at MOPED

Post-translational modifications for C1orf112 Gene

  • Modification sites at PhosphoSitePlus
  • Ubiquitination at Lys25 and Lys783

Other Protein References for C1orf112 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C1orf112 Gene

Domains for C1orf112 Gene

Protein Domains for C1orf112 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for C1orf112 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C1orf112: view

No data available for Gene Families and UniProtKB/Swiss-Prot for C1orf112 Gene

Function for C1orf112 Gene

Phenotypes for C1orf112 Gene

MGI mutant phenotypes for C1orf112:
inferred from 1 alleles
GenomeRNAi human phenotypes for C1orf112:
genes like me logo Genes that share phenotypes with C1orf112: view

miRNA for C1orf112 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , Transcription Factor Targeting and HOMER Transcription for C1orf112 Gene

Localization for C1orf112 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for C1orf112 Gene COMPARTMENTS Subcellular localization image for C1orf112 gene
Compartment Confidence
cytosol 2
mitochondrion 2
nucleus 2
extracellular 1
peroxisome 1
plasma membrane 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C1orf112 Gene

Pathways for C1orf112 Gene

SuperPathways for C1orf112 Gene

No Data Available

Interacting Proteins for C1orf112 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000286031%0d%0a9606.ENSP00000344818%0d%0a
Selected Interacting proteins: ENSP00000286031 for C1orf112 Gene via STRING

Symbol External ID(s) Details
UBC

Gene Ontology (GO) - Biological Process for C1orf112 Gene

None

No data available for Pathways by source for C1orf112 Gene

Transcripts for C1orf112 Gene

Unigene Clusters for C1orf112 Gene

Chromosome 1 open reading frame 112:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for C1orf112 Gene

ExUns: 1 ^ 2a · 2b ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7a · 7b · 7c · 7d ^ 8 ^ 9a · 9b ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20 ^
SP1:
SP2: - -
SP3: - -
SP4: - - - -
SP5: - - -
SP6: - - - - -

ExUns: 21 ^ 22 ^ 23 ^ 24 ^ 25a · 25b
SP1:
SP2:
SP3:
SP4:
SP5:
SP6:

Relevant External Links for C1orf112 Gene

GeneLoc Exon Structure for
C1orf112
ECgene alternative splicing isoforms for
C1orf112

Expression for C1orf112 Gene

mRNA expression in normal human tissues for C1orf112 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for C1orf112 Gene

SOURCE GeneReport for Unigene cluster for C1orf112 Gene Hs.443551

genes like me logo Genes that share expressions with C1orf112: view

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for C1orf112 Gene

Orthologs for C1orf112 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C1orf112 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C1H1orf112 35
  • 99.3 (n)
  • 99.18 (a)
C1orf112 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia C16H1orf112 35
  • 87.29 (n)
  • 83.71 (a)
C1orf112 36
  • 78 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C1orf112 36
  • 79 (a)
OneToOne
C7H1orf112 35
  • 87.55 (n)
  • 83.98 (a)
mouse
(Mus musculus)
Mammalia BC055324 35
  • 81.36 (n)
  • 72.99 (a)
BC055324 16
BC055324 36
  • 68 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia C1orf112 36
  • 73 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 67 (a)
OneToMany
-- 36
  • 66 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia LOC498265 35
  • 81.67 (n)
  • 74.76 (a)
chicken
(Gallus gallus)
Aves C1orf112 36
  • 55 (a)
OneToOne
C8H1ORF112 35
  • 68.05 (n)
  • 63.04 (a)
lizard
(Anolis carolinensis)
Reptilia C1orf112 36
  • 49 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia c1orf112 35
  • 59.97 (n)
  • 54.89 (a)
Str.481 35
zebrafish
(Danio rerio)
Actinopterygii C20H1orf112 36
  • 43 (a)
OneToOne
si:dkey-97o5.1 35
  • 54.41 (n)
  • 46.59 (a)
Species with no ortholog for C1orf112:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C1orf112 Gene

ENSEMBL:
Gene Tree for C1orf112 (if available)
TreeFam:
Gene Tree for C1orf112 (if available)

Paralogs for C1orf112 Gene

No data available for Paralogs for C1orf112 Gene

Variants for C1orf112 Gene

Sequence variations from dbSNP and Humsavar for C1orf112 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs725526 -- 169,852,405(+) AATTA(C/G)TATAG intron-variant
rs730083 -- 169,798,280(-) AAAAA(A/G)AGAGA intron-variant
rs2056981 -- 169,821,210(-) ATAAC(C/T)TAATT intron-variant
rs2143121 -- 169,845,407(-) TATTT(C/T)AAGAA intron-variant
rs2143122 -- 169,845,392(-) CCACA(A/G)CCACC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C1orf112 Gene

Variant ID Type Subtype PubMed ID
dgv146e1 CNV Complex 17122850
nsv428268 CNV Gain+Loss 18775914
nsv872542 CNV Gain 21882294
esv2719417 CNV Deletion 23290073

Relevant External Links for C1orf112 Gene

HapMap Linkage Disequilibrium report
C1orf112

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C1orf112 Gene

Disorders for C1orf112 Gene

Relevant External Links for C1orf112

Human Genome Epidemiology (HuGE) Navigator
C1orf112
genes like me logo Genes that share disorders with C1orf112: view

No data available for UniProtKB/Swiss-Prot for C1orf112 Gene

Publications for C1orf112 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. Pre-B-cell leukemia homeobox 1 (PBX1) shows functional and possible genetic association with bone mineral density variation. (PMID: 19064610) Cheung C.L. … Kung A.W. (Hum. Mol. Genet. 2009) 3
  4. Follow-up of a major linkage peak on chromosome 1 reveals suggestive QTLs associated with essential hypertension: GenNet study. (PMID: 19536175) Ehret G.B. … Chakravarti A. (Eur. J. Hum. Genet. 2009) 3
  5. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3

Products for C1orf112 Gene

Sources for C1orf112 Gene

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