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Aliases for C1orf105 Gene

Aliases for C1orf105 Gene

  • Chromosome 1 Open Reading Frame 105 2 3 5

External Ids for C1orf105 Gene

Previous GeneCards Identifiers for C1orf105 Gene

  • GC01P169122
  • GC01P170656
  • GC01P143613

Summaries for C1orf105 Gene

GeneCards Summary for C1orf105 Gene

C1orf105 (Chromosome 1 Open Reading Frame 105) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C1orf105 Gene

Genomics for C1orf105 Gene

Regulatory Elements for C1orf105 Gene

Enhancers for C1orf105 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01F172447 0.5 Ensembl ENCODE 31.1 +30.4 30429 7.1 PKNOX1 WRNIP1 ARID4B FEZF1 DMAP1 ZNF2 ZNF143 FOS SP5 MXD4 C1orf105 PIGC SUCO LOC102724528
GH01F172472 0.5 Ensembl 29 +52.7 52687 1.6 HDAC1 PKNOX1 TBL1XR1 ZNF766 GATA2 CREM ZBTB2 NCOA1 CEBPB ZEB2 C1orf105 SUCO PIGC RNU6-157P LOC102724528
GH01F172475 0.6 Ensembl ENCODE 27 +57.5 57518 5.5 PKNOX1 ARID4B DMAP1 FEZF1 ZNF2 ZNF48 ZNF766 GATA2 FOS KAT8 C1orf105 PIGC SUCO LOC102724528
GH01F172483 0.6 ENCODE 24.5 +63.5 63544 1.9 PKNOX1 RAD21 ZNF366 RCOR1 FOS MCM3 CEBPB TFDP1 ZNF217 SMARCA4 PIGC C1orf105 SUCO LOC102724528
GH01F172389 1.4 FANTOM5 Ensembl ENCODE 11.7 -24.0 -23959 13.8 PKNOX1 MLX FEZF1 ZNF2 CBX5 ZNF207 FOS DEK JUNB TBX21 PIGC LOC100422549 LOC391136 ENSG00000253060 RNU6-157P C1orf105 DNM3OS
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around C1orf105 on UCSC Golden Path with GeneCards custom track

Genomic Location for C1orf105 Gene

Chromosome:
1
Start:
172,420,515 bp from pter
End:
172,468,831 bp from pter
Size:
48,317 bases
Orientation:
Plus strand

Genomic View for C1orf105 Gene

Genes around C1orf105 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C1orf105 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C1orf105 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C1orf105 Gene

Proteins for C1orf105 Gene

  • Protein details for C1orf105 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    O95561-CA105_HUMAN
    Recommended name:
    Uncharacterized protein C1orf105
    Protein Accession:
    O95561
    Secondary Accessions:
    • Q8IY02

    Protein attributes for C1orf105 Gene

    Size:
    183 amino acids
    Molecular mass:
    21209 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C1orf105 Gene

Post-translational modifications for C1orf105 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for C1orf105 Gene

Domains & Families for C1orf105 Gene

Protein Domains for C1orf105 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for C1orf105 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C1orf105: view

No data available for Gene Families and UniProtKB/Swiss-Prot for C1orf105 Gene

Function for C1orf105 Gene

Gene Ontology (GO) - Molecular Function for C1orf105 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with C1orf105: view

Phenotypes for C1orf105 Gene

genes like me logo Genes that share phenotypes with C1orf105: view

Animal Model Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for C1orf105 Gene

Localization for C1orf105 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for C1orf105 Gene COMPARTMENTS Subcellular localization image for C1orf105 gene
Compartment Confidence
nucleus 2
cytosol 1
extracellular 1
mitochondrion 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C1orf105 Gene

Pathways & Interactions for C1orf105 Gene

SuperPathways for C1orf105 Gene

No Data Available

Interacting Proteins for C1orf105 Gene

Gene Ontology (GO) - Biological Process for C1orf105 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C1orf105 Gene

Transcripts for C1orf105 Gene

Unigene Clusters for C1orf105 Gene

Chromosome 1 open reading frame 105:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C1orf105 Gene

No ASD Table

Relevant External Links for C1orf105 Gene

GeneLoc Exon Structure for
C1orf105
ECgene alternative splicing isoforms for
C1orf105

Expression for C1orf105 Gene

mRNA expression in normal human tissues for C1orf105 Gene

mRNA differential expression in normal tissues according to GTEx for C1orf105 Gene

This gene is overexpressed in Testis (x19.7), Heart - Left Ventricle (x14.4), and Heart - Atrial Appendage (x14.1).

Protein differential expression in normal tissues from HIPED for C1orf105 Gene

This gene is overexpressed in Heart (39.7), Adrenal (12.0), Frontal cortex (11.1), and Fetal heart (6.2).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C1orf105 Gene



Protein tissue co-expression partners for C1orf105 Gene

NURSA nuclear receptor signaling pathways regulating expression of C1orf105 Gene:

C1orf105

SOURCE GeneReport for Unigene cluster for C1orf105 Gene:

Hs.517991
genes like me logo Genes that share expression patterns with C1orf105: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for C1orf105 Gene

Orthologs for C1orf105 Gene

This gene was present in the common ancestor of mammals.

Orthologs for C1orf105 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C1H1orf105 34
  • 98.91 (n)
C1orf105 35
  • 97 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C7H1orf105 34
  • 84.88 (n)
-- 35
  • 80 (a)
OneToMany
-- 35
  • 68 (a)
OneToMany
cow
(Bos Taurus)
Mammalia C16H1orf105 34
  • 83.06 (n)
rat
(Rattus norvegicus)
Mammalia RGD1309106 34
  • 75 (n)
mouse
(Mus musculus)
Mammalia 4930558K02Rik 34 16 35
  • 72.1 (n)
Species where no ortholog for C1orf105 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C1orf105 Gene

ENSEMBL:
Gene Tree for C1orf105 (if available)
TreeFam:
Gene Tree for C1orf105 (if available)

Paralogs for C1orf105 Gene

No data available for Paralogs for C1orf105 Gene

Variants for C1orf105 Gene

Sequence variations from dbSNP and Humsavar for C1orf105 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs786205667 Likely pathogenic 172,441,964(-) GAAAC(C/T)AAAGG intron-variant, reference, missense
rs1041911 -- 172,462,846(-) gcagt(A/G)agcca intron-variant
rs10522870 -- 172,466,601(+) ACACA(A/C)ACACA intron-variant
rs10573338 -- 172,460,408(+) TAGGC(-/TG)TGTTT intron-variant
rs1057520 -- 172,417,156(-) GCTCA(C/T)TTCCA intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for C1orf105 Gene

Variant ID Type Subtype PubMed ID
esv2669467 CNV deletion 23128226
esv3587924 CNV loss 21293372
nsv947449 CNV duplication 23825009

Variation tolerance for C1orf105 Gene

Residual Variation Intolerance Score: 84.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.23; 62.22% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C1orf105 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
C1orf105

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C1orf105 Gene

Disorders for C1orf105 Gene

Relevant External Links for C1orf105

Human Genome Epidemiology (HuGE) Navigator
C1orf105
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C1orf105

No disorders were found for C1orf105 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C1orf105 Gene

Publications for C1orf105 Gene

  1. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4 64
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3 64
  4. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3 64
  5. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3 64

Products for C1orf105 Gene

Sources for C1orf105 Gene

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