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Aliases for C1orf105 Gene

Aliases for C1orf105 Gene

  • Chromosome 1 Open Reading Frame 105 2 3 5

External Ids for C1orf105 Gene

Previous GeneCards Identifiers for C1orf105 Gene

  • GC01P169122
  • GC01P170656
  • GC01P143613

Summaries for C1orf105 Gene

GeneCards Summary for C1orf105 Gene

C1orf105 (Chromosome 1 Open Reading Frame 105) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C1orf105 Gene

Genomics for C1orf105 Gene

Regulatory Elements for C1orf105 Gene

Enhancers for C1orf105 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around C1orf105 on UCSC Golden Path with GeneCards custom track

Genomic Location for C1orf105 Gene

172,420,515 bp from pter
172,468,831 bp from pter
48,317 bases
Plus strand

Genomic View for C1orf105 Gene

Genes around C1orf105 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C1orf105 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C1orf105 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C1orf105 Gene

Proteins for C1orf105 Gene

  • Protein details for C1orf105 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized protein C1orf105
    Protein Accession:
    Secondary Accessions:
    • Q8IY02

    Protein attributes for C1orf105 Gene

    183 amino acids
    Molecular mass:
    21209 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C1orf105 Gene

Proteomics data for C1orf105 Gene at MOPED

Post-translational modifications for C1orf105 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C1orf105 Gene

No data available for DME Specific Peptides for C1orf105 Gene

Domains & Families for C1orf105 Gene

Protein Domains for C1orf105 Gene


Suggested Antigen Peptide Sequences for C1orf105 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C1orf105: view

No data available for Gene Families and UniProtKB/Swiss-Prot for C1orf105 Gene

Function for C1orf105 Gene

Phenotypes for C1orf105 Gene

GenomeRNAi human phenotypes for C1orf105:
genes like me logo Genes that share phenotypes with C1orf105: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for C1orf105 Gene

Localization for C1orf105 Gene

Subcellular locations from

Jensen Localization Image for C1orf105 Gene COMPARTMENTS Subcellular localization image for C1orf105 gene
Compartment Confidence
nucleus 2
cytosol 1
extracellular 1
mitochondrion 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C1orf105 Gene

Pathways & Interactions for C1orf105 Gene

SuperPathways for C1orf105 Gene

No Data Available

Interacting Proteins for C1orf105 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
Selected Interacting proteins: ENSP00000356700 O95561-CA105_HUMAN for C1orf105 Gene via STRING UniProtKB

Gene Ontology (GO) - Biological Process for C1orf105 Gene


No data available for Pathways by source and SIGNOR curated interactions for C1orf105 Gene

Drugs & Compounds for C1orf105 Gene

No Compound Related Data Available

Transcripts for C1orf105 Gene

Unigene Clusters for C1orf105 Gene

Chromosome 1 open reading frame 105:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for C1orf105 Gene

No ASD Table

Relevant External Links for C1orf105 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C1orf105 Gene

mRNA expression in normal human tissues for C1orf105 Gene

mRNA differential expression in normal tissues according to GTEx for C1orf105 Gene

This gene is overexpressed in Testis (x19.7), Heart - Left Ventricle (x14.4), and Heart - Atrial Appendage (x14.1).

Protein differential expression in normal tissues from HIPED for C1orf105 Gene

This gene is overexpressed in Heart (39.7), Adrenal (12.0), Frontal cortex (11.1), and Fetal heart (6.2).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C1orf105 Gene

SOURCE GeneReport for Unigene cluster for C1orf105 Gene Hs.517991

genes like me logo Genes that share expression patterns with C1orf105: view

Protein tissue co-expression partners for C1orf105 Gene

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for C1orf105 Gene

Orthologs for C1orf105 Gene

This gene was present in the common ancestor of mammals.

Orthologs for C1orf105 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia C16H1orf105 35
  • 83.06 (n)
  • 71.04 (a)
(Canis familiaris)
Mammalia C7H1orf105 35
  • 84.88 (n)
  • 73.77 (a)
-- 36
  • 68 (a)
-- 36
  • 80 (a)
(Mus musculus)
Mammalia 4930558K02Rik 35
  • 72.1 (n)
  • 60.11 (a)
4930558K02Rik 16
4930558K02Rik 36
  • 58 (a)
(Pan troglodytes)
Mammalia C1H1orf105 35
  • 98.91 (n)
  • 97.81 (a)
C1orf105 36
  • 97 (a)
(Rattus norvegicus)
Mammalia RGD1309106 35
  • 75 (n)
  • 60.8 (a)
Species with no ortholog for C1orf105:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C1orf105 Gene

Gene Tree for C1orf105 (if available)
Gene Tree for C1orf105 (if available)

Paralogs for C1orf105 Gene

No data available for Paralogs for C1orf105 Gene

Variants for C1orf105 Gene

Sequence variations from dbSNP and Humsavar for C1orf105 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs16844498 - 172,462,193(+) GAACA(A/G)TGAAA intron-variant, reference, missense
rs1129942 - 172,468,452(+) AGAAA(A/G)CATTC reference, missense, utr-variant-3-prime
rs1041911 -- 172,462,846(-) gcagt(A/G)agcca intron-variant
rs2157450 -- 172,460,921(-) TGCTA(A/C)AGGGG intron-variant
rs2001132 -- 172,466,852(-) TATTC(C/T)CCCTG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C1orf105 Gene

Variant ID Type Subtype PubMed ID
esv2669467 CNV Deletion 23128226

Variation tolerance for C1orf105 Gene

Residual Variation Intolerance Score: 84.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.23; 62.22% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for C1orf105 Gene

Disorders for C1orf105 Gene

Relevant External Links for C1orf105

Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for C1orf105 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C1orf105 Gene

Publications for C1orf105 Gene

  1. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4 67
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  4. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3
  5. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PMID: 21832049) OlA!h J. … OvA!di J. (J. Biol. Chem. 2011) 3

Products for C1orf105 Gene

Sources for C1orf105 Gene