C1orf105 Gene
protein-coding GIFtS: 38
GCID: GC01P172389
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chromosome 1 open reading frame 105
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Aliases
for C1orf105 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Chromosome 1 Open Reading Frame 1051 2 | | Uncharacterized Protein C1orf1052 |
Export aliases for C1orf105 gene to outside databasesPrevious GC identifers: GC01P169122 GC01P170656 GC01P143613 |
Summaries
for C1orf105 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for C1orf105 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000001.10 NC_018912.1 NT_004487.19
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the C1orf105 gene promoter:
COUP-TF1 USF1 COUP HNF-4alpha2 HNF-4alpha1 Evi-1 Pax-3 COUP-TF USF-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for C1orf105
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C1orf105 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 1q24.3 Ensembl cytogenetic band: 1q24.3 HGNC cytogenetic band: 1q24.3C1orf105 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01P172389: view genomic region
(about GC identifiers)
Start:
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172,389,828 bp from pter |
End:
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172,437,971 bp from pter |
Size:
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48,144 bases |
Orientation:
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plus strand |
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Proteins
for C1orf105 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CA105_HUMAN, O95561 (See
protein sequence)Recommended Name: Uncharacterized protein C1orf105 Size: 183 amino acids; 21209 Da
Secondary accessions: Q8IY02Explore the universe of human proteins at neXtProt for C1orf105: NX_O95561
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_O95561
C1orf105 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_640333.3
ENSEMBL proteins: ENSP00000356700 ENSP00000435216 ENSP00000431442 ENSP00000356698
Human Recombinant Protein Products for C1orf105:
C1orf105 Antibody Products:
Assay Products for C1orf105: |
Protein
Domains /
Families
for C1orf105 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: O95561 |
Function
for C1orf105 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C1orf105
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C1orf105
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: C1orf105 (NM_139240) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for C1orf105 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C1orf105 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C1orf105 |
|
Pathways & Interactions
for C1orf105 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for C1orf105
STRING Interaction
Network Preview (showing 5 interactants - click image to see 9)
5/9 Interacting proteins for C1orf105 (ENSP000003567004) via UniProtKB, MINT, STRING, and/or I2D (see all 9)About this table
|
Drugs & Compounds
for C1orf105 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for C1orf105
Search CenterWatch for drugs/clinical trials and news about C1orf105 / CA105
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Transcripts
for C1orf105 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for C1orf105 gene: NM_139240.3 Unigene Cluster for C1orf105: Chromosome 1 open reading frame 105 Hs.517991 [show with all ESTs]Unigene Representative Sequence: BC0384105 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000367727(uc001gik.3) ENST00000460397 ENST00000488100 ENST00000367726
ENST00000367725
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C1orf105
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C1orf105
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: C1orf105 (NM_139240) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for C1orf105 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C1orf105 |
Additional cDNA sequence: AL035295.1 BC038410.1 5 DOTS entries: DT.100018732 DT.91899623 DT.121390294 DT.121390224 DT.444042 24/31 AceView cDNA sequences (see all 31): AI828633 AL035295 AW510869 BI827163 W56365 AA954090 AI191972 BV203381 BX104688 AI052662 BQ188191 BM873777 AA923390 AI659525 AI033856 NM_139240 AA693603 CD386750 BC038410 AW444454 CB159852 BQ185352 W56576 AA994252
GeneLoc Exon Structure
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Expression
for C1orf105 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| C1orf105 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: ATTATAAAGA
About this image
See C1orf105 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for C1orf105
SOURCE GeneReport for Unigene cluster: Hs.517991
SABiosciences Custom PCR Arrays for C1orf105
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C1orf105
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat C1orf105 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C1orf105 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C1orf105 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C1orf105 |
Orthologs
for C1orf105 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of human and mouse.
Orthologs for C1orf105 gene from 1/5 species (see all 5) About this table
ENSEMBL Gene Tree for C1orf105 (if available)
TreeFam Gene Tree for C1orf105 (if available) |
Paralogs
for C1orf105 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for C1orf105 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 1 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
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HapMap Linkage Disequilibrium report for C1orf105 (172389828 - 172437971 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for C1orf105: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing C1orf105 |
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Disorders
/ Diseases
for C1orf105 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
 C1orf105 for disorders About MalaCards
C1orf105 for disorders About GeneDecksing
Human Genome Epidemiology (HuGE) Navigator: C1orf105 (1 document)
Export disorders for C1orf105 gene to outside databases
|
Publications
for C1orf105 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for C1orf105 gene integrated from 9 sources:
(articles sorted by number of sources associating them with C1orf105) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
- Interactions of pathological hallmark proteins: tubul in polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (2011)
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
- Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1 Olsen J.V....Mann M. (2006)
- Hepatitis C virus core protein interacts with 14-3-3 protein and activates the kinase Raf-1. (PubMed id )2 Aoki H.... Hino O. (2000)
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External Searches for C1orf105 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
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Genome Databases showing C1orf105 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing C1orf105 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing C1orf105 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for C1orf105 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for C1orf105 gene:
Search GeneIP for patents involving C1orf105
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for C1orf105 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for C1orf105 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for C1orf105 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C1orf105 | | | OriGene Protein Over-expression Lysate for C1orf105 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for C1orf105 | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C1orf105 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C1orf105 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for C1orf105 | | OriGene Custom Protein Services for C1orf105 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat C1orf105 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing C1orf105 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C1orf105 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat C1orf105 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C1orf105 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C1orf105 |
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 | | | C1orf105 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C1orf105 |
|  |  |  |  | | | | Search ThermoFisher Antibodies for C1orf105 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C1orf105 |
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