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Aliases for C1orf101 Gene

Aliases for C1orf101 Gene

  • Chromosome 1 Open Reading Frame 101 2 3 5

External Ids for C1orf101 Gene

Previous GeneCards Identifiers for C1orf101 Gene

  • GC01P240951
  • GC01P242691
  • GC01P244618
  • GC01P215007

Summaries for C1orf101 Gene

GeneCards Summary for C1orf101 Gene

C1orf101 (Chromosome 1 Open Reading Frame 101) is a Protein Coding gene. An important paralog of this gene is CATSPERD.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C1orf101 Gene

Genomics for C1orf101 Gene

Regulatory Elements for C1orf101 Gene

Promoters for C1orf101 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around C1orf101 on UCSC Golden Path with GeneCards custom track

Genomic Location for C1orf101 Gene

Chromosome:
1
Start:
244,452,100 bp from pter
End:
244,641,177 bp from pter
Size:
189,078 bases
Orientation:
Plus strand

Genomic View for C1orf101 Gene

Genes around C1orf101 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C1orf101 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C1orf101 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C1orf101 Gene

Proteins for C1orf101 Gene

  • Protein details for C1orf101 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5SY80-CA101_HUMAN
    Recommended name:
    Uncharacterized protein C1orf101
    Protein Accession:
    Q5SY80
    Secondary Accessions:
    • B4DZR4
    • B7Z7X5
    • E9PEA3
    • Q8IYZ6

    Protein attributes for C1orf101 Gene

    Size:
    951 amino acids
    Molecular mass:
    109662 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BC028392; Type=Frameshift; Positions=418; Evidence={ECO:0000305};

    Alternative splice isoforms for C1orf101 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for C1orf101 Gene

Proteomics data for C1orf101 Gene at MOPED

Post-translational modifications for C1orf101 Gene

  • Glycosylation at Asn 61, Asn 114, Asn 472, and Asn 535
  • Modification sites at PhosphoSitePlus

Other Protein References for C1orf101 Gene

No data available for DME Specific Peptides for C1orf101 Gene

Domains & Families for C1orf101 Gene

Protein Domains for C1orf101 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for C1orf101 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C1orf101: view

No data available for Gene Families and UniProtKB/Swiss-Prot for C1orf101 Gene

Function for C1orf101 Gene

Phenotypes for C1orf101 Gene

GenomeRNAi human phenotypes for C1orf101:
genes like me logo Genes that share phenotypes with C1orf101: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for C1orf101 Gene

Localization for C1orf101 Gene

Subcellular locations from UniProtKB/Swiss-Prot for C1orf101 Gene

Membrane; Single-pass type I membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for C1orf101 Gene COMPARTMENTS Subcellular localization image for C1orf101 gene
Compartment Confidence
plasma membrane 4
endoplasmic reticulum 1
extracellular 1

No data available for Gene Ontology (GO) - Cellular Components for C1orf101 Gene

Pathways & Interactions for C1orf101 Gene

SuperPathways for C1orf101 Gene

No Data Available

Interacting Proteins for C1orf101 Gene

Gene Ontology (GO) - Biological Process for C1orf101 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C1orf101 Gene

Drugs & Compounds for C1orf101 Gene

No Compound Related Data Available

Transcripts for C1orf101 Gene

Unigene Clusters for C1orf101 Gene

Chromosome 1 open reading frame 101:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for C1orf101 Gene

No ASD Table

Relevant External Links for C1orf101 Gene

GeneLoc Exon Structure for
C1orf101
ECgene alternative splicing isoforms for
C1orf101

Expression for C1orf101 Gene

mRNA expression in normal human tissues for C1orf101 Gene

mRNA differential expression in normal tissues according to GTEx for C1orf101 Gene

This gene is overexpressed in Testis (x14.8).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C1orf101 Gene



SOURCE GeneReport for Unigene cluster for C1orf101 Gene Hs.459534

genes like me logo Genes that share expression patterns with C1orf101: view

Protein tissue co-expression partners for C1orf101 Gene

- Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for C1orf101 Gene

Orthologs for C1orf101 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C1orf101 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia C16H1orf101 35
  • 80.44 (n)
  • 68.34 (a)
C1orf101 36
  • 64 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C7H1orf101 35
  • 81.68 (n)
  • 70.42 (a)
C1orf101 36
  • 70 (a)
OneToOne
mouse
(Mus musculus)
Mammalia LOC102632386 35
  • 65.37 (n)
  • 52.75 (a)
Gm7068 16
Gm16432 36
  • 18 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia C1H1orf101 35
  • 99.19 (n)
  • 98 (a)
C1orf101 36
  • 98 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia RGD1565309 35
  • 65.7 (n)
  • 52.02 (a)
oppossum
(Monodelphis domestica)
Mammalia C1orf101 36
  • 39 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia C1orf101 36
  • 42 (a)
OneToOne
chicken
(Gallus gallus)
Aves C3H1orf101 35
  • 51.84 (n)
  • 38.51 (a)
C1orf101 36
  • 29 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia C1orf101 36
  • 35 (a)
OneToOne
Species with no ortholog for C1orf101:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C1orf101 Gene

ENSEMBL:
Gene Tree for C1orf101 (if available)
TreeFam:
Gene Tree for C1orf101 (if available)

Paralogs for C1orf101 Gene

Paralogs for C1orf101 Gene

genes like me logo Genes that share paralogs with C1orf101: view

Variants for C1orf101 Gene

Sequence variations from dbSNP and Humsavar for C1orf101 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs11586356 - 244,477,914(+) ACCCA(A/C/T)GACAG nc-transcript-variant, reference, missense, utr-variant-5-prime
VAR_035494 A breast cancer sample
rs58602830 - 244,477,592(+) CAGAA(A/T)CTTGT nc-transcript-variant, reference, missense, utr-variant-5-prime
rs905251 -- 244,639,715(+) TCCCA(G/T)TGCAT intron-variant
rs955460 -- 244,630,664(+) atgca(C/G)gaagt intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C1orf101 Gene

Variant ID Type Subtype PubMed ID
nsv516557 CNV Gain 19592680
nsv818866 CNV Gain 17921354
esv2726640 CNV Deletion 23290073
esv2659474 CNV Deletion 23128226
esv2107521 CNV Deletion 18987734
esv2726651 CNV Deletion 23290073
esv2726662 CNV Deletion 23290073
esv992950 CNV Deletion 20482838
esv1291880 CNV Deletion 17803354
esv24695 CNV Loss 19812545
esv2726673 CNV Deletion 23290073
nsv528017 CNV Gain 19592680
esv1134718 CNV Deletion 17803354
nsv5154 CNV Insertion 18451855
esv2639096 CNV Deletion 19546169
nsv873394 CNV Gain 21882294

Variation tolerance for C1orf101 Gene

Residual Variation Intolerance Score: 67% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.59; 44.92% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C1orf101 Gene

HapMap Linkage Disequilibrium report
C1orf101

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C1orf101 Gene

Disorders for C1orf101 Gene

Relevant External Links for C1orf101

Genetic Association Database (GAD)
C1orf101
Human Genome Epidemiology (HuGE) Navigator
C1orf101
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C1orf101

No disorders were found for C1orf101 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C1orf101 Gene

Publications for C1orf101 Gene

  1. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4 67
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3

Products for C1orf101 Gene

Sources for C1orf101 Gene

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