Free for academic non-profit institutions. Other users need a Commercial license

Aliases for C1orf101 Gene

Aliases for C1orf101 Gene

  • Chromosome 1 Open Reading Frame 101 2 3 5

External Ids for C1orf101 Gene

Previous GeneCards Identifiers for C1orf101 Gene

  • GC01P240951
  • GC01P242691
  • GC01P244618
  • GC01P215007

Summaries for C1orf101 Gene

GeneCards Summary for C1orf101 Gene

C1orf101 (Chromosome 1 Open Reading Frame 101) is a Protein Coding gene. An important paralog of this gene is CATSPERD.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C1orf101 Gene

Genomics for C1orf101 Gene

Regulatory Elements for C1orf101 Gene

Enhancers for C1orf101 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01F244730 1 FANTOM5 ENCODE 23 +278.5 278485 1.1 ATF1 MAX CTBP2 CREM C1orf100 C1orf101 ENSG00000282317 RPL37P8
GH01F244917 0.3 FANTOM5 22.9 +465.2 465169 0.1 C1orf101 RNU6-947P GC01P244944 ENSG00000273175
GH01F244460 0.2 ENCODE 15.2 +9.2 9204 2.4 PKNOX1 SIN3A FEZF1 GLI4 YY1 GLIS2 ZNF143 KLF7 SP3 YY2 C1orf101 DESI2 ADSS GC01M244569
GH01F244435 0.8 Ensembl ENCODE 11.2 -15.3 -15285 3.1 ATF1 PKNOX1 SIN3A YBX1 ZNF2 FOS ZNF263 SP3 JUNB TSHZ1 C1orf101 RPL37P8 ADSS LOC105373264
GH01F244449 0.6 ENCODE 11 -0.8 -764 3.6 HDGF PKNOX1 ARNT CREB3L1 ARID4B SIN3A DMAP1 ZNF2 YY1 CBX5 LOC101928068 C1orf101 COX20 ENSG00000236031 LOC105373264
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around C1orf101 on UCSC Golden Path with GeneCards custom track

Promoters for C1orf101 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

Genomic Location for C1orf101 Gene

244,452,100 bp from pter
244,641,177 bp from pter
189,078 bases
Plus strand

Genomic View for C1orf101 Gene

Genes around C1orf101 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C1orf101 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C1orf101 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C1orf101 Gene

Proteins for C1orf101 Gene

  • Protein details for C1orf101 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized protein C1orf101
    Protein Accession:
    Secondary Accessions:
    • B4DZR4
    • B7Z7X5
    • E9PEA3
    • Q8IYZ6

    Protein attributes for C1orf101 Gene

    951 amino acids
    Molecular mass:
    109662 Da
    Quaternary structure:
    No Data Available
    • Sequence=BC028392; Type=Frameshift; Positions=418; Evidence={ECO:0000305};

    Alternative splice isoforms for C1orf101 Gene


neXtProt entry for C1orf101 Gene

Post-translational modifications for C1orf101 Gene

  • Glycosylation at Asn 61, Asn 114, Asn 472, and Asn 535
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for C1orf101 Gene

Domains & Families for C1orf101 Gene

Protein Domains for C1orf101 Gene


Suggested Antigen Peptide Sequences for C1orf101 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C1orf101: view

No data available for Gene Families and UniProtKB/Swiss-Prot for C1orf101 Gene

Function for C1orf101 Gene

Phenotypes for C1orf101 Gene

GenomeRNAi human phenotypes for C1orf101:
genes like me logo Genes that share phenotypes with C1orf101: view

Animal Model Products

Inhibitory RNA Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for C1orf101 Gene

Localization for C1orf101 Gene

Subcellular locations from UniProtKB/Swiss-Prot for C1orf101 Gene

Membrane; Single-pass type I membrane protein.

Subcellular locations from

Jensen Localization Image for C1orf101 Gene COMPARTMENTS Subcellular localization image for C1orf101 gene
Compartment Confidence
plasma membrane 4
endoplasmic reticulum 1
extracellular 1

Gene Ontology (GO) - Cellular Components for C1orf101 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
GO:0036128 CatSper complex IEA --
genes like me logo Genes that share ontologies with C1orf101: view

Pathways & Interactions for C1orf101 Gene

SuperPathways for C1orf101 Gene

No Data Available

Interacting Proteins for C1orf101 Gene

Gene Ontology (GO) - Biological Process for C1orf101 Gene


No data available for Pathways by source and SIGNOR curated interactions for C1orf101 Gene

Transcripts for C1orf101 Gene

Unigene Clusters for C1orf101 Gene

Chromosome 1 open reading frame 101:
Representative Sequences:

Inhibitory RNA Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C1orf101 Gene

No ASD Table

Relevant External Links for C1orf101 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C1orf101 Gene

mRNA expression in normal human tissues for C1orf101 Gene

mRNA differential expression in normal tissues according to GTEx for C1orf101 Gene

This gene is overexpressed in Testis (x14.8).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C1orf101 Gene

Protein tissue co-expression partners for C1orf101 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of C1orf101 Gene:


SOURCE GeneReport for Unigene cluster for C1orf101 Gene:

genes like me logo Genes that share expression patterns with C1orf101: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for C1orf101 Gene

Orthologs for C1orf101 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C1orf101 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia C1H1orf101 34
  • 99.19 (n)
C1orf101 35
  • 98 (a)
(Canis familiaris)
Mammalia C7H1orf101 34
  • 81.68 (n)
C1orf101 35
  • 70 (a)
(Bos Taurus)
Mammalia C16H1orf101 34
  • 80.44 (n)
C1orf101 35
  • 64 (a)
(Rattus norvegicus)
Mammalia RGD1565309 34
  • 65.7 (n)
(Mus musculus)
Mammalia LOC102632386 34
  • 65.37 (n)
Gm16432 35
  • 18 (a)
Gm7068 16
(Ornithorhynchus anatinus)
Mammalia C1orf101 35
  • 42 (a)
(Monodelphis domestica)
Mammalia C1orf101 35
  • 39 (a)
(Gallus gallus)
Aves C3H1orf101 34
  • 51.84 (n)
C1orf101 35
  • 29 (a)
(Anolis carolinensis)
Reptilia C1orf101 35
  • 35 (a)
Species where no ortholog for C1orf101 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C1orf101 Gene

Gene Tree for C1orf101 (if available)
Gene Tree for C1orf101 (if available)

Paralogs for C1orf101 Gene

Paralogs for C1orf101 Gene

genes like me logo Genes that share paralogs with C1orf101: view

Variants for C1orf101 Gene

Sequence variations from dbSNP and Humsavar for C1orf101 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
VAR_035494 A breast cancer sample
rs10399868 -- 244,577,216(+) AAAAA(A/G)TCAAC intron-variant
rs10429925 -- 244,550,447(+) GAAAA(A/T)TGAAA intron-variant
rs10465638 -- 244,622,693(+) AAATC(A/G)TGAAA intron-variant
rs10524749 -- 244,489,475(+) TTTTT(-/TTTTTTT)GGTGG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C1orf101 Gene

Variant ID Type Subtype PubMed ID
esv1134718 CNV deletion 17803354
esv1291880 CNV deletion 17803354
esv2107521 CNV deletion 18987734
esv24695 CNV loss 19812545
esv2639096 CNV deletion 19546169
esv2659474 CNV deletion 23128226
esv2726640 CNV deletion 23290073
esv2726651 CNV deletion 23290073
esv2726662 CNV deletion 23290073
esv2726673 CNV deletion 23290073
esv3007798 CNV deletion 24192839
esv3589408 CNV loss 21293372
esv3589409 CNV loss 21293372
esv3589410 CNV loss 21293372
esv3589411 CNV loss 21293372
esv3589412 CNV loss 21293372
esv992950 CNV deletion 20482838
nsv1119770 CNV deletion 24896259
nsv1119771 CNV deletion 24896259
nsv1133956 CNV deletion 24896259
nsv1137861 CNV deletion 24896259
nsv1160479 CNV deletion 26073780
nsv5154 CNV insertion 18451855
nsv516557 CNV gain 19592680
nsv528017 CNV gain 19592680
nsv549492 CNV loss 21841781
nsv818866 CNV gain 17921354
nsv945426 CNV duplication 23825009

Variation tolerance for C1orf101 Gene

Residual Variation Intolerance Score: 67% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.59; 44.92% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C1orf101 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C1orf101 Gene

Disorders for C1orf101 Gene

Relevant External Links for C1orf101

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for C1orf101 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C1orf101 Gene

Publications for C1orf101 Gene

  1. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4 64
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3 64
  4. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 64
  5. The consensus coding sequences of human breast and colorectal cancers. (PMID: 16959974) Sjoeblom T. … Velculescu V.E. (Science 2006) 4 64

Products for C1orf101 Gene

Sources for C1orf101 Gene

Loading form....