C1QTNF9B Gene
protein-coding GIFtS: 34
GCID: GC13M024462
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C1q and tumor necrosis factor related protein 9B
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Aliases
for C1QTNF9B gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| C1q And Tumor Necrosis Factor Related Protein 9B1 2 | | Complement C1q And Tumor Necrosis Factor-Related Protein 9B2 | | CTRP9B1 2 3 | | Complement C1q Tumor Necrosis Factor-Related Protein 9B2 | | C1q/TNF-Related Protein 9B2 3 | | Complement C1q And Tumor Necrosis Factor-Related Protein 9-Like3 | | Collagen Triple Helix Repeat-Containing2 | | |
Export aliases for C1QTNF9B gene to outside databasesPrevious GC identifer: GC13M005276 |
Summaries
for C1QTNF9B gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for C1QTNF9B gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000013.10 NC_018924.1 NT_024524.14
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for C1QTNF9B
Other transcription factors
Search SABiosciences Chromatin IP Primers for C1QTNF9B
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C1QTNF9B |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 13q12.12 Ensembl cytogenetic band: 13q12.12 HGNC cytogenetic band: 13q12.12C1QTNF9B Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 13 GeneLoc Exon Structure GeneLoc location for GC13M024462: view genomic region
(about GC identifiers)
Start:
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24,465,238 bp from pter |
End:
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24,476,794 bp from pter |
Size:
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11,557 bases |
Orientation:
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minus strand |
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Proteins
for C1QTNF9B gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: C1T9B_HUMAN, B2RNN3 (See
protein sequence)Recommended Name: Complement C1q and tumor necrosis factor-related protein 9B precursor Size: 333 amino acids; 34713 Da
Subunit: Interacts with CTRP9A and ADIPOQ. Forms heterotrimers and heterooligomeric complexes with CTRP9A
Subcellular location: Secreted. Note=Heteromeric complex formation with CTRP9A or ADIPOQ is required for secretion,otherwise, it is retained in the endoplasmic reticulum
Secondary accessions: A2A3T6 B9EH31 Q0VGC5 Q5VX65 Q5VX66 Q8IUU4Alternative splicing: 2 isoforms: B2RNN3-1 B2RNN3-2 Explore the universe of human proteins at neXtProt for C1QTNF9B: NX_B2RNN3
C1QTNF9B Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_001007538.1
ENSEMBL proteins: ENSP00000371580 ENSP00000371575 ENSP00000371572 ENSP00000371489
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005581 | collagen |
IEA | -- |
C1QTNF9B for ontologies About GeneDecksing
C1QTNF9B Antibody Products:
Assay Products for C1QTNF9B: |
Protein
Domains /
Families
for C1QTNF9B gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
C1QTNF9B for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry B2RNN3ProtoNet protein and cluster: B2RNN3 UniProtKB/Swiss-Prot: C1T9B_HUMAN, B2RNN3Similarity: Contains 1 C1q domainSimilarity: Contains 3 collagen-like domains |
Function
for C1QTNF9B gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C1QTNF9B
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C1QTNF9B
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
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Synthesis Service for C1QTNF9B | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C1QTNF9B |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C1QTNF9B |
|
Pathways & Interactions
for C1QTNF9B gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for C1QTNF9B
|
Drugs & Compounds
for C1QTNF9B gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for C1QTNF9B
Search CenterWatch for drugs/clinical trials and news about C1QTNF9B / C1T9B
|
Transcripts
for C1QTNF9B gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for C1QTNF9B gene: NM_001007537.1 Unigene Cluster for C1QTNF9B: C1q and tumor necrosis factor related protein 9B Hs.740810 [show with all ESTs]Unigene Representative Sequence: BC1370045 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000382145(uc001uoz.1) ENST00000556521(uc010tcv.1) ENST00000382140
ENST00000382137(uc010tcw.2 uc010tcx.2) ENST00000382057
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C1QTNF9B
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C1QTNF9B
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: C1QTNF9B (NM_001007537) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for C1QTNF9B | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C1QTNF9B |
Additional cDNA sequence: BC110413.1 BC137004.1 BC137006.1 BC144450.1 2 DOTS entries: DT.97800636 DT.309897 5 AceView cDNA sequences: BI833629 BQ072381 AA578056 CA425716 AW973741
GeneLoc Exon Structure
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Expression
for C1QTNF9B gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| C1QTNF9B expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GGCCCTATTG
About this image
See C1QTNF9B Protein Expression from SPIRE MOPED and PaxDB
SOURCE GeneReport for Unigene cluster: Hs.740810
UniProtKB/Swiss-Prot: C1T9B_HUMAN, B2RNN3Tissue specificity: Expressed at low levels. Not expressed in adipose tissues
SABiosciences Custom PCR Arrays for C1QTNF9B
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C1QTNF9B
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat C1QTNF9B | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C1QTNF9B | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C1QTNF9B | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C1QTNF9B |
Orthologs
for C1QTNF9B gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for C1QTNF9B gene from 3/11 species (see all 11) About this table
ENSEMBL Gene Tree for C1QTNF9B (if available)
TreeFam Gene Tree for C1QTNF9B (if available) |
Paralogs
for C1QTNF9B gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for C1QTNF9B gene
- C1QL32 COL8A22 C1QL22 C1QTNF92 C1QTNF52 OTOL12 C1QB2 COL10A12
- C1QTNF32 C1QA2 COL8A12 C1QL12 C1QTNF72 C1QTNF22 C1QC2 C1QL42
- ADIPOQ2
18/36 SIMAP similar genes for C1QTNF9B using alignment to 1 protein entry: C1T9B_HUMAN(see all similar genes):C1QTNF9 ADIPOQ OTOL1 C1QTNF2 COL11A2 C1QTNF7
COL11A1 COL9A1 COL2A1 COL4A2 COL5A1 COL6A3
COL8A2 COL9A2 COL24A1 C1QC C1QL3 COL17A1
C1QTNF9B for paralogs About GeneDecksing
|
Genomic Variants
for C1QTNF9B gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 13 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for C1QTNF9B (24465238 - 24476794 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for C1QTNF9B: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing C1QTNF9B |
|
Disorders
/ Diseases
for C1QTNF9B gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
C1QTNF9B for disorders About GeneDecksing
OMIM gene information: 614148
OMIM disorders: --
1  disease for C1QTNF9B: About MalaCardsmyopia
Export disorders for C1QTNF9B gene to outside databases
|
Publications
for C1QTNF9B gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for C1QTNF9B gene integrated from 9 sources:
(articles sorted by number of sources associating them with C1QTNF9B) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- CTRP8 and CTRP9B are novel proteins that hetero-oligo merize with C1q/TNF family members. (PubMed id 19666007)1, 2 Peterson J.M....Wong G.W. (2009)
- C1q and its growing family. (PubMed id 17544811)1, 3 Ghai R....Kishore U. (2007)
- Genetic variants at 13q12.12 are associated with high myopia in the Han Chinese population. (PubMed id 21640322)1 Shi Y....Yang Z. (2011)
- The DNA sequence and analysis of human chromosome 13. (PubMed id 15057823)2 Dunham A.... Ross M.T. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
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External Searches for C1QTNF9B gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing C1QTNF9B gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing C1QTNF9B gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing C1QTNF9B gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for C1QTNF9B gene:
Search GeneIP for patents involving C1QTNF9B
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for C1QTNF9B gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
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 | |
 |
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 | | | C1QTNF9B Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C1QTNF9B |
|  |  |  | | | | Search ThermoFisher Antibodies for C1QTNF9B |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C1QTNF9B |
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