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Aliases for C1QTNF9 Gene

Aliases for C1QTNF9 Gene

  • C1q And Tumor Necrosis Factor Related Protein 9 2 3
  • C1QTNF9A 3 4 6
  • Complement C1q And Tumor Necrosis Factor-Related Protein 9 3 4
  • Complement C1q And Tumor Necrosis Factor-Related Protein 9A 3
  • Complement C1q Tumor Necrosis Factor-Related Protein 9A 3
  • Complement C1q Tumor Necrosis Factor-Related Protein 9 3
  • CTRP9, 6
  • CTRP9 3
  • AQL1 3

External Ids for C1QTNF9 Gene

Previous GeneCards Identifiers for C1QTNF9 Gene

  • GC13P023779
  • GC13P024881
  • GC13P005695

Summaries for C1QTNF9 Gene

GeneCards Summary for C1QTNF9 Gene

C1QTNF9 (C1q And Tumor Necrosis Factor Related Protein 9) is a Protein Coding gene. GO annotations related to this gene include hormone activity. An important paralog of this gene is COL8A1.

UniProtKB/Swiss-Prot for C1QTNF9 Gene

  • Probable adipokine. Activates AMPK, AKT, and p44/42 MAPK signaling pathways (By similarity).

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C1QTNF9 Gene

Genomics for C1QTNF9 Gene

Regulatory Elements for C1QTNF9 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for C1QTNF9 Gene

24,307,166 bp from pter
24,322,535 bp from pter
15,370 bases
Plus strand

Genomic View for C1QTNF9 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for C1QTNF9 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C1QTNF9 Gene

Proteins for C1QTNF9 Gene

  • Protein details for C1QTNF9 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Complement C1q and tumor necrosis factor-related protein 9A
    Protein Accession:
    Secondary Accessions:
    • A2A3T6
    • Q0VGC5
    • Q5VX65
    • Q5VX66
    • Q8IUU4

    Protein attributes for C1QTNF9 Gene

    333 amino acids
    Molecular mass:
    34681 Da
    Quaternary structure:
    • Multimers (predominantly trimers). Interacts with ADIPOQ via the C1q domain to form a heterotrimeric complex (By similarity). Interacts with CTRP9B. Forms heterotrimers and heterooligomeric complexes with CTRP9B.

neXtProt entry for C1QTNF9 Gene

Proteomics data for C1QTNF9 Gene at MOPED

Post-translational modifications for C1QTNF9 Gene

  • Glycosylation at Lys73 and Lys127
  • Modification sites at PhosphoSitePlus

Other Protein References for C1QTNF9 Gene

Antibody Products

No data available for DME Specific Peptides for C1QTNF9 Gene

Domains for C1QTNF9 Gene

Protein Domains for C1QTNF9 Gene

Suggested Antigen Peptide Sequences for C1QTNF9 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • P0C862
  • Contains 1 C1q domain.
  • Contains 3 collagen-like domains.
genes like me logo Genes that share domains with C1QTNF9: view

No data available for Gene Families for C1QTNF9 Gene

Function for C1QTNF9 Gene

Molecular function for C1QTNF9 Gene

UniProtKB/Swiss-Prot Function: Probable adipokine. Activates AMPK, AKT, and p44/42 MAPK signaling pathways (By similarity).

Gene Ontology (GO) - Molecular Function for C1QTNF9 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005179 hormone activity IEA --
GO:0005515 protein binding --
genes like me logo Genes that share ontologies with C1QTNF9: view

Animal Model Products

CRISPR Products

miRNA for C1QTNF9 Gene

miRTarBase miRNAs that target C1QTNF9

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C1QTNF9

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for C1QTNF9 Gene

Localization for C1QTNF9 Gene

Subcellular locations from UniProtKB/Swiss-Prot for C1QTNF9 Gene


Subcellular locations from

Jensen Localization Image for C1QTNF9 Gene COMPARTMENTS Subcellular localization image for C1QTNF9 gene
Compartment Confidence
extracellular 5
cytosol 1
mitochondrion 1
nucleus 1
peroxisome 1

Gene Ontology (GO) - Cellular Components for C1QTNF9 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region IEA --
GO:0005581 collagen trimer IEA --
genes like me logo Genes that share ontologies with C1QTNF9: view

Pathways for C1QTNF9 Gene

SuperPathways for C1QTNF9 Gene

No Data Available

Interacting Proteins for C1QTNF9 Gene

Gene Ontology (GO) - Biological Process for C1QTNF9 Gene


No data available for Pathways by source for C1QTNF9 Gene

Transcripts for C1QTNF9 Gene

mRNA/cDNA for C1QTNF9 Gene

Unigene Clusters for C1QTNF9 Gene

C1q and tumor necrosis factor related protein 9:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C1QTNF9

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for C1QTNF9

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C1QTNF9 Gene

No ASD Table

Relevant External Links for C1QTNF9 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C1QTNF9 Gene

mRNA expression in normal human tissues for C1QTNF9 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for C1QTNF9 Gene

SOURCE GeneReport for Unigene cluster for C1QTNF9 Gene Hs.362854

mRNA Expression by UniProt/SwissProt for C1QTNF9 Gene

Tissue specificity: Expressed predominantly in adipose tissue.
genes like me logo Genes that share expressions with C1QTNF9: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA differential expression in normal tissues for C1QTNF9 Gene

Orthologs for C1QTNF9 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C1QTNF9 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia -- 36
  • 98 (a)
-- 36
  • 98 (a)
C1QTNF9 35
  • 98.9 (n)
  • 98.5 (a)
(Bos Taurus)
Mammalia C1QTNF9 36
  • 85 (a)
(Canis familiaris)
Mammalia -- 36
  • 89 (a)
(Mus musculus)
Mammalia C1qtnf9 16
C1qtnf9 36
  • 85 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 74 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 63 (a)
(Gallus gallus)
Aves -- 36
  • 64 (a)
(Anolis carolinensis)
Reptilia -- 36
  • 61 (a)
(Danio rerio)
Actinopterygii c1qtnf9 35
  • 58.82 (n)
  • 56.88 (a)
c1qtnf9 36
  • 54 (a)
Species with no ortholog for C1QTNF9:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C1QTNF9 Gene

Gene Tree for C1QTNF9 (if available)
Gene Tree for C1QTNF9 (if available)

Paralogs for C1QTNF9 Gene

genes like me logo Genes that share paralogs with C1QTNF9: view

Variants for C1QTNF9 Gene

Sequence variations from dbSNP and Humsavar for C1QTNF9 Gene

SNP ID Clin Chr 13 pos Sequence Context AA Info Type MAF
rs1320617 -- 24,321,917(+) ATTCT(A/G)TGTAA utr-variant-3-prime
rs1815680 -- 24,321,783(+) GTTTA(A/T)AAATC utr-variant-3-prime
rs1815681 -- 24,321,789(+) AAATC(C/T)GCCAC utr-variant-3-prime
rs1815682 -- 24,321,794(+) CGCCA(C/G)ACCAT utr-variant-3-prime
rs1961993 -- 24,316,879(+) AGGGT(A/C)ACATA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C1QTNF9 Gene

Variant ID Type Subtype PubMed ID
esv2422502 CNV Duplication 17116639
esv2747122 CNV Deletion 23290073
esv5325 CNV Complex 18987735
nsv455837 CNV Gain 19166990
nsv525965 CNV Gain 19592680
dgv1561n71 CNV Gain 21882294
esv2751136 CNV Loss 17911159
nsv899932 CNV Gain 21882294
esv2422202 CNV Duplication 17116639
esv2751137 CNV Gain 17911159
nsv899936 CNV Gain 21882294
nsv899938 CNV Gain 21882294
nsv455842 CNV Gain 19166990
nsv899940 CNV Loss 21882294
nsv832567 CNV Loss 17160897

Relevant External Links for C1QTNF9 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C1QTNF9 Gene

Disorders for C1QTNF9 Gene

No disorders were found for C1QTNF9 Gene.

No data available for UniProtKB/Swiss-Prot for C1QTNF9 Gene

Publications for C1QTNF9 Gene

  1. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PMID: 12975309) Clark H.F. … Gray A.M. (Genome Res. 2003) 2 3 4
  2. Identification and characterization of CTRP9, a novel secreted glycoprotein, from adipose tissue that reduces serum glucose in mice and forms heterotrimers with adiponectin. (PMID: 18787108) Wong G.W. … Lodish H.F. (FASEB J. 2009) 2 3
  3. The DNA sequence and analysis of human chromosome 13. (PMID: 15057823) Dunham A. … Ross M.T. (Nature 2004) 4
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4
  5. CTRP8 and CTRP9B are novel proteins that hetero-oligomerize with C1q/TNF family members. (PMID: 19666007) Peterson J.M. … Wong G.W. (Biochem. Biophys. Res. Commun. 2009) 4

Products for C1QTNF9 Gene

Sources for C1QTNF9 Gene

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