Free for academic non-profit institutions. Other users need a Commercial license

Aliases for C1QTNF6 Gene

Aliases for C1QTNF6 Gene

  • C1q And Tumor Necrosis Factor Related Protein 6 2 3
  • CTFP6 3 6
  • CTRP6 3 4
  • Complement C1q Tumor Necrosis Factor-Related Protein 6 3
  • Complement-C1q Tumor Necrosis Factor-Related Protein 6 3
  • ZACRP6 3

External Ids for C1QTNF6 Gene

Summaries for C1QTNF6 Gene

GeneCards Summary for C1QTNF6 Gene

C1QTNF6 (C1q And Tumor Necrosis Factor Related Protein 6) is a Protein Coding gene. GO annotations related to this gene include identical protein binding. An important paralog of this gene is COL8A1.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C1QTNF6 Gene

Genomics for C1QTNF6 Gene

Genomic Location for C1QTNF6 Gene

Start:
37,180,166 bp from pter
End:
37,199,385 bp from pter
Size:
19,220 bases
Orientation:
Minus strand

Genomic View for C1QTNF6 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for C1QTNF6 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C1QTNF6 Gene

Regulatory Elements for C1QTNF6 Gene

Proteins for C1QTNF6 Gene

  • Protein details for C1QTNF6 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9BXI9-C1QT6_HUMAN
    Recommended name:
    Complement C1q tumor necrosis factor-related protein 6
    Protein Accession:
    Q9BXI9
    Secondary Accessions:
    • Q5H9G8
    • Q6ZRM7

    Protein attributes for C1QTNF6 Gene

    Size:
    259 amino acids
    Molecular mass:
    28669 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for C1QTNF6 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for C1QTNF6 Gene

Proteomics data for C1QTNF6 Gene at MOPED

Post-translational modifications for C1QTNF6 Gene

Other Protein References for C1QTNF6 Gene

No data available for DME Specific Peptides for C1QTNF6 Gene

Domains for C1QTNF6 Gene

UniProtKB/Swiss-Prot:

C1QT6_HUMAN
Domain:
  • Contains 1 C1q domain.:
    • Q9BXI9
  • Contains 1 collagen-like domain.:
    • Q9BXI9
genes like me logo Genes that share domains with C1QTNF6: view

No data available for Gene Families for C1QTNF6 Gene

Function for C1QTNF6 Gene

Gene Ontology (GO) - Molecular Function for C1QTNF6 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
GO:0042802 identical protein binding IEA --
genes like me logo Genes that share ontologies with C1QTNF6: view

miRNA for C1QTNF6 Gene

miRTarBase miRNAs that target C1QTNF6

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for C1QTNF6 Gene

Localization for C1QTNF6 Gene

Subcellular locations from UniProtKB/Swiss-Prot for C1QTNF6 Gene

Secreted.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for C1QTNF6 Gene COMPARTMENTS Subcellular localization image for C1QTNF6 gene
Compartment Confidence
extracellular 4
plasma membrane 2
cytosol 1
endoplasmic reticulum 1
lysosome 1
mitochondrion 1
nucleus 1
peroxisome 1

Gene Ontology (GO) - Cellular Components for C1QTNF6 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005581 collagen trimer IEA --
GO:0005615 extracellular space IEA --
genes like me logo Genes that share ontologies with C1QTNF6: view

Pathways for C1QTNF6 Gene

SuperPathways for C1QTNF6 Gene

No Data Available

Interacting Proteins for C1QTNF6 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000338812%0d%0a9606.ENSP00000221566%0d%0a
Selected Interacting proteins: ENSP00000338812 Q9BXI9-C1QT6_HUMAN for C1QTNF6 Gene via STRING UniProtKB

Gene Ontology (GO) - Biological Process for C1QTNF6 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0051259 protein oligomerization --
GO:0070208 protein heterotrimerization IEA --
genes like me logo Genes that share ontologies with C1QTNF6: view

No data available for Pathways by source for C1QTNF6 Gene

Transcripts for C1QTNF6 Gene

Unigene Clusters for C1QTNF6 Gene

C1q and tumor necrosis factor related protein 6:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for C1QTNF6 Gene

ExUns: 1 ^ 2a · 2b ^ 3a · 3b · 3c ^ 4 ^ 5a · 5b · 5c · 5d · 5e ^ 6
SP1: - - -
SP2: -
SP3: - - - -
SP4:
SP5: - - -

Relevant External Links for C1QTNF6 Gene

GeneLoc Exon Structure for
C1QTNF6
ECgene alternative splicing isoforms for
C1QTNF6

Expression for C1QTNF6 Gene

mRNA expression in normal human tissues for C1QTNF6 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for C1QTNF6 Gene

SOURCE GeneReport for Unigene cluster for C1QTNF6 Gene Hs.22011

genes like me logo Genes that share expressions with C1QTNF6: view

Orthologs for C1QTNF6 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C1QTNF6 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C1QTNF6 36
  • 99.04 (n)
  • 99.64 (a)
C1QTNF6 37
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia C1QTNF6 36
  • 81.93 (n)
  • 72.69 (a)
C1QTNF6 37
  • 69 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C1QTNF6 36
  • 82.7 (n)
  • 76.37 (a)
C1QTNF6 37
  • 70 (a)
OneToOne
mouse
(Mus musculus)
Mammalia C1qtnf6 36
  • 75.8 (n)
  • 69.5 (a)
C1qtnf6 16
C1qtnf6 37
  • 67 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia -- 37
  • 65 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 37
  • 53 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia C1qtnf6 36
  • 76.49 (n)
  • 70.93 (a)
chicken
(Gallus gallus)
Aves -- 37
  • 56 (a)
OneToMany
C1QTNF6 36
  • 63.99 (n)
  • 58.63 (a)
lizard
(Anolis carolinensis)
Reptilia -- 37
  • 55 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii c1qtnf6a 36
  • 64.36 (n)
  • 58.99 (a)
c1qtnf6a 37
  • 51 (a)
ManyToMany
CABZ01084570.1 37
  • 49 (a)
ManyToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 37
  • 16 (a)
OneToMany
Species with no ortholog for C1QTNF6:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C1QTNF6 Gene

ENSEMBL:
Gene Tree for C1QTNF6 (if available)
TreeFam:
Gene Tree for C1QTNF6 (if available)

Paralogs for C1QTNF6 Gene

Selected SIMAP similar genes for C1QTNF6 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with C1QTNF6: view

Variants for C1QTNF6 Gene

Sequence variations from dbSNP and Humsavar for C1QTNF6 Gene

SNP ID Clin Chr 22 pos Sequence Context AA Info Type MAF
rs1900 -- 37,189,056(+) TGGAT(C/T)ATTCA upstream-variant-2KB, intron-variant
rs8279 -- 37,180,322(-) CACAG(C/T)CGAGG utr-variant-3-prime
rs9286 -- 37,180,446(-) GGTGT(C/T)CCCCT utr-variant-3-prime
rs229515 -- 37,180,032(+) TGACA(C/T)GGCTG downstream-variant-500B
rs229517 -- 37,181,697(-) ACAtt(A/T)ttttt utr-variant-3-prime, intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C1QTNF6 Gene

Variant ID Type Subtype PubMed ID
esv34015 CNV Loss 18971310
nsv829203 CNV Loss 20364138
nsv915018 CNV Loss 21882294
nsv915019 CNV Loss 21882294
nsv915020 CNV Loss 21882294

Relevant External Links for C1QTNF6 Gene

HapMap Linkage Disequilibrium report
C1QTNF6

Disorders for C1QTNF6 Gene

Relevant External Links for C1QTNF6

Genetic Association Database (GAD)
C1QTNF6
Human Genome Epidemiology (HuGE) Navigator
C1QTNF6
genes like me logo Genes that share disorders with C1QTNF6: view

No data available for UniProtKB/Swiss-Prot for C1QTNF6 Gene

Publications for C1QTNF6 Gene

  1. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PMID: 12975309) Clark H.F. … Gray A.M. (Genome Res. 2003) 2 3 4
  2. Signal peptide prediction based on analysis of experimentally verified cleavage sites. (PMID: 15340161) Zhang Z. … Henzel W.J. (Protein Sci. 2004) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. Meta-analysis of genome-wide association study data identifies additional type 1 diabetes risk loci. (PMID: 18978792) Cooper J.D. … Todd J.A. (Nat. Genet. 2008) 3 49
  5. Shared and distinct genetic variants in type 1 diabetes and celiac disease. (PMID: 19073967) Smyth D.J. … Todd J.A. (N. Engl. J. Med. 2008) 3 49

Products for C1QTNF6 Gene

Sources for C1QTNF6 Gene

Back to Top

Content