Home
GeneCards Guide
Suite
- MalaCards
- GeneALaCart
- GeneDecks
- GeneIP
- GeneLoc
Terms and Conditions
- Terms of Use
- 3rd Party Notice
About Us
User Feedback
Mirror sites

Set Analyses:

Generates a file of GeneCards annotations for your list of genes

Advanced Search

Search By

Section (entire)

for

All GeneCards Within gene subset (to enable gene prioritization):
or upload a file of gene symbols

Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

C1QTNF5 Gene

protein-coding GIFtS: 49
GCID: GC11M119243

C1q and tumor necrosis factor related protein 5

Explore 14 diseases affiliated with
C1QTNF5 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
C1q And Tumor Necrosis Factor Related Protein 5¹ ²
CTRP5¹ ² ³ ⁵
LORD¹ ² ⁵
DKFZp586B0621¹
Complement C1q Tumor Necrosis Factor-Related Protein 5²

External Ids:	HGNC: 14344¹	Entrez Gene: 114902²	Ensembl: ENSG00000223953⁷	OMIM: 608752⁵	UniProtKB: Q9BXJ0³

Export aliases for C1QTNF5 gene to outside databases

Previous GC identifers: GC11U990608 GC11M120721 GC11M118747 GC11M118715 GC11M115151

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for C1QTNF5:

This gene encodes a member of the a member of the C1q/tumor necrosis factor superfamily. The encoded protein may be a

component of basement membranes and may play a role in cell adhesion. This gene is contained entirely within the 3'

UTR of the membrane frizzled-related protein gene on chromosome 11q23 and both genes are expressed from a bicistronic

transcript. Mutations in this gene have been associated with late-onset retinal degeneration.(provided by RefSeq, May

2010)

Gene Wiki entry for C1QTNF5

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000011.9 NC_018922.1 NT_033899.8

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the C1QTNF5 gene promoter:
STAT1 HTF MyoD C/EBPalpha Egr-4 CREB S8 POU2F1 deltaCREB POU2F1a
Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids

Search SABiosciences Chromatin IP Primers for C1QTNF5

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C1QTNF5

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11q23.3 Ensembl cytogenetic band: 11q23.3 HGNC cytogenetic band: 11q23.3

C1QTNF5 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
C1QTNF5 gene location

GeneLoc information about chromosome 11 GeneLoc Exon Structure

GeneLoc location for GC11M119243: view genomic region (about GC identifiers)

Start:	119,209,652 bp from pter	End:	119,217,383 bp from pter
Size:	7,732 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: C1QT5_HUMAN, Q9BXJ0 (See protein sequence)

Recommended Name: Complement C1q tumor necrosis factor-related protein 5 precursor

Size: 243 amino acids; 25298 Da

Subcellular location: Secreted (Probable)

1 PDB 3D structure from and Proteopedia for C1QTNF5:

4F3J (3D)

Secondary accessions: A6NDD3 B0YJ35 Q335M2 Q8N6P2 Q9UFX4

Explore the universe of human proteins at neXtProt for C1QTNF5: NX_Q9BXJ0

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q9BXJ0

C1QTNF5 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_056460.1

ENSEMBL proteins:

ENSP00000431140 ENSP00000402389

Human Recombinant Protein Products for C1QTNF5:

	Browse Purified and Recombinant Proteins at EMD Millipore
	Browse R&D Systems for human recombinant proteins
	Enzo Life Sciences proteins for C1QTNF5
	Browse OriGene full length recombinant human proteins expressed in human HEK293 cells Browse OriGene Protein Over-expression Lysates OriGene Custom Protein Services for C1QTNF5
	GenScript Custom Purified and Recombinant Proteins Services for C1QTNF5
	Novus Biologicals C1QTNF5 Proteins Novus Biologicals C1QTNF5 Lysate
	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins
	Uscn Proteins for C1QTNF5

Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005581	collagen	IEA	--

C1QTNF5 for ontologies About GeneDecksing

C1QTNF5 Antibody Products:

	Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	R&D Systems Antibodies for C1QTNF5
	OriGene Antibodies (see all 2): C1QTNF5 OriGene Custom Antibody Services for C1QTNF5
	GenScript Custom Superior Antibodies Services for C1QTNF5
	Novus Biologicals C1QTNF5 Antibodies
	Abcam antibodies for C1QTNF5
	Uscn Antibodies for C1QTNF5
	ThermoFisher Antibodies for C1QTNF5

Assay Products for C1QTNF5:

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for C1QTNF5
	Enzo Life Sciences assays for C1QTNF5
	Uscn ELISAs and CLIAs for C1QTNF5

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

C1QTNF5 for domains About GeneDecksing

3 InterPro domains/families:

IPR008983 Tumour_necrosis_fac-like_dom

IPR008160 Collagen

IPR001073 C1q

Graphical View of Domain Structure for InterPro Entry Q9BXJ0

ProtoNet protein and cluster: Q9BXJ0

2 Blocks protein families:

IPB001073 Complement C1q protein

IPB008160 Collagen triple helix repeat

UniProtKB/Swiss-Prot: C1QT5_HUMAN, Q9BXJ0

Similarity: Contains 1 C1q domain

Similarity: Contains 1 collagen-like domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Phenotypes:
1 GenomeRNAi human phenotype for C1QTNF5:

Increased gamma-H2AX phosphory

5 MGI mutant phenotypes (inferred from 2 alleles) (MGI details for C1qtnf5):

cardiovascular system

nervous system

normal

pigmentation

vision/eye

C1QTNF5 for phenotypes About GeneDecksing

Animal Models:

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for C1QTNF5

miRNA Products:		OriGene 3'-UTR Clone: C1QTNF5 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat C1QTNF5
		5 QIAGEN miScript miRNA Assays for microRNAs that regulate C1QTNF5:
		hsa-miR-3194-5p hsa-miR-4251 hsa-miR-4290 hsa-miR-3921 hsa-miR-635
		Browse SwitchGear 3'UTR luciferase reporter plasmids

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for C1QTNF5 (see all 7) OriGene shRNA RFP: C1QTNF5 OriGene siRNA: C1QTNF5
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat C1QTNF5
		Sirion Biotech Custom design and validation of potent shRNA sequences against C1QTNF5

Gene Editing Products:			DNA2.0 Custom Protein Engineering Service for C1QTNF5
			Sirion Biotech Customized adenovirus for overexpression of C1QTNF5 Sirion Biotech Customized adenovirus for potent knockdown of C1QTNF5

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C1QTNF5 (see all 7) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C1QTNF5 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: C1QTNF5 (NM_015645)
		Browse Sino Biological Human cDNA Clones
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for C1QTNF5
		Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat C1QTNF5

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for C1QTNF5
		Search LifeMap BioReagents cell lines for C1QTNF5
		Sirion Biotech Customized stable knockdown cell line services for C1QTNF5 Sirion Biotech Customized inducible knockdown cell line services for C1QTNF5 Sirion Biotech Customized stable overexpressing cell line services for C1QTNF5 Sirion Biotech Customized inducible overexpressing cell line services for C1QTNF5

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C1QTNF5

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for C1QTNF5

STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

2 Interacting proteins for C1QTNF5 (Q9BXJ0³ ENSP00000402389⁴) via UniProtKB, MINT, STRING, and/or I2D

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
SLC2A4	P14672³	I2D: score=2
MFRP	ENSP00000391664⁴	STRING: ENSP00000391664

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for C1QTNF5
Search CenterWatch for drugs/clinical trials and news about C1QTNF5 / C1QT5

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for C1QTNF5 gene:

NM_015645.3

Unigene Cluster for C1QTNF5:

C1q and tumor necrosis factor related protein 5

Hs.632102 [show with all ESTs]

Unigene Representative Sequence: BC036675

3 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000525657 ENST00000528368 ENST00000445041

miRNA Products:		OriGene 3'-UTR Clone: C1QTNF5 Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat C1QTNF5
		5 QIAGEN miScript miRNA Assays for microRNAs that regulate C1QTNF5:
		hsa-miR-3194-5p hsa-miR-4251 hsa-miR-4290 hsa-miR-3921 hsa-miR-635
		Browse SwitchGear 3'UTR luciferase reporter plasmids

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for C1QTNF5 (see all 7) OriGene shRNA RFP: C1QTNF5 OriGene siRNA: C1QTNF5
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat C1QTNF5
		Sirion Biotech Custom design and validation of potent shRNA sequences against C1QTNF5

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C1QTNF5 (see all 7) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C1QTNF5 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: C1QTNF5 (NM_015645)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for C1QTNF5
		Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat C1QTNF5

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C1QTNF5 Browse OriGene validated miRNA SYBR primer pairs
		Search SABiosciences RT² qPCR Primer Assays in human, mouse, rat C1QTNF5
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C1QTNF5
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C1QTNF5

Additional cDNA sequence:

AB055505.1 AF086482.1 AF329841.1 AJ862823.1 AK055132.1 AK295203.1 AL110261.1 AY358383.1

BC029485.1 BC036675.1

6 DOTS entries:

DT.411344 DT.95170481 DT.92418575 DT.100744595 DT.95170478 DT.100020201

24/96 AceView cDNA sequences (see all 96):

AI805087 BM021127 BM893587 BM966810 AF086482 CA397875 BM021381 AI564511

AI783751 AI619600 AL110261 BF724241 CA390714 BM929480 NM_015645 BM719761

BU742804 BM547549 BE138819 BM924569 BM544255 AW190639 CK904254 BM966954

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

C1QTNF5 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GGGCAGTGGC

About this image

C1QTNF5 expression in embryonic tissues and stem cells
Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

2 LifeMap In Vivo Development Anatomical Compartments/Cells

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Brain

Neural Tube

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See C1QTNF5 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for C1QTNF5

SOURCE GeneReport for Unigene cluster: Hs.632102

SABiosciences Custom PCR Arrays for C1QTNF5

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C1QTNF5 Browse OriGene validated miRNA SYBR primer pairs
		Search SABiosciences RT² qPCR Primer Assays in human, mouse, rat C1QTNF5
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C1QTNF5
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C1QTNF5

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C1QTNF5

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of chordates.

Orthologs for C1QTNF5 gene from 3/9 species (see all 9) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	C1QTNF5¹	C1q and tumor necrosis factor related protein 5	73.11(n) 73.66(a)		769989 XM_001232466.2 XP_001232467.2
lizard (Anolis carolinensis)	Reptilia	C1QTNF5⁶	--	70(a)	1 ↔ 1	GL343797.1(29769-32504)
zebrafish (Danio rerio)	Actinopterygii	wufb02f05²	Transcribed sequence with weak similarity to protein more	73.67(n)		BI705095.1

ENSEMBL Gene Tree for C1QTNF5 (if available)
TreeFam Gene Tree for C1QTNF5 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for C1QTNF5 gene

C1QL3² COL8A2² C1QL2² C1QTNF9² OTOL1² C1QB² COL10A1² C1QTNF3²

C1QTNF9B² C1QA² COL8A1² C1QL1² C1QTNF7² C1QTNF2² C1QC² C1QL4²

ADIPOQ²

10 SIMAP similar genes for C1QTNF5 using alignment to 2 protein entries: C1QT5_HUMAN (see all proteins):

MFRP CUBN OTOL1 C1QC ADIPOQ DKFZp686L21135

C1QL3 C1QB C1QTNF9 C1QTNF9B

C1QTNF5 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

Human Gene Mutation Database (HGMD): C1QTNF5

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing C1QTNF5

DNA2.0 Custom Variant and Variant Library Synthesis for C1QTNF5

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

C1QTNF5 for disorders           About GeneDecksing

OMIM gene information: 608752
OMIM disorders: 605670
UniProtKB/Swiss-Prot: C1QT5_HUMAN, Q9BXJ0

Defects in C1QTNF5 are a cause of late-onset retinal degeneration (LORD) [MIM:605670]. LORD is an autosomal

dominant disorder characterized by onset in the fifth to sixth decade with night blindness and punctate yellow-white

deposits in the retinal fundus, progressing to severe central and peripheral degeneration, with choroidal

neovascularization and chorioretinal atrophy

14 diseases for C1QTNF5: About MalaCards

late-onset retinal degeneration retinal degeneration, late-onset, autosomal dominant retinal degeneration retinitis

chorioretinitis night blindness hemiplegia blindness

spasticity choroiditis

1 Novoseek disease relationship for C1QTNF5 gene About this table

Disease	-log (P-Val)	Hits	PubMed IDs for Articles with Shared Sentences (# sentences)
retinal degeneration	76.2	1	12944416 (1)

Human Genome Epidemiology (HuGE) Navigator: C1QTNF5 (2 documents)

Export disorders for C1QTNF5 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for C1QTNF5 gene, integrated from 9 sources (see all 23):
(articles sorted by number of sources associating them with C1QTNF5)

Utopia: connect your pdf to the dynamic
world of online information

Mutation in a short-chain collagen gene, CTRP5, results in extracellular deposit formation in late-onset retinal degeneration: a genetic model for age-related macular degeneration. (PubMed id 12944416)^{1, 2, 3, 9} Hayward C.... Wright A.F. (2003)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Signal peptide prediction based on analysis of experimentally verified cleavage sites. (PubMed id 15340161)^{1, 2} Zhang Z. and Henzel W.J. (2004)
The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)^{1, 2} Clark H.F.... Gray A.M. (2003)
Late-onset macular degeneration and long anterior lens zonules result from a CTRP5 gene mutation. (PubMed id 16123441)^{1, 9} Ayyagari R....Sieving P.A. (2005)
Long anterior lens zonules in late-onset retinal degeneration (L-ORD). (PubMed id 16376663)^{1, 9} Subrayan V....Dhillon B. (2005)
The characterization of retinal phenotype in a family with C1QTNF5-related late-onset retinal degeneration. (PubMed id 22277927)¹ Vincent A....Heon E. (2012)
The global gene-expression profiles of U-937 human mac rophages treated with Tat peptide and Tat-FITC conjugate. (PubMed id 22632162)¹ Lin C.W....Jan M.S. (2012)
Effects of aerobic exercise training on C1q tumor necr osis factor a-related protein isoform 5 (myonectin): association with insulin re sistance and mitochondrial DNA density in women. (PubMed id 22031510)¹ Lim S....Park K.S. (2012)
Characterisation of a C1qtnf5 Ser163Arg knock-in mouse model of late-onset retinal macular degeneration. (PubMed id 22110650)¹ Shu X....Wright A.F. (2011)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Disorders
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 114902	HGNC: 14344	AceView: C1QTNF5andMFRP	Ensembl:ENSG00000223953	euGenes: HUgn114902
ECgene: C1QTNF5	H-InvDB: C1QTNF5

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for C1QTNF5	Pharmacogenomics, SNPs, Pathways
ATLAS Chromosomes in Cancer entry for C1QTNF5	Genetics and Cytogenetics in Oncology and Haematology

Intellectual Property for C1QTNF5 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for C1QTNF5 gene:
Search GeneIP for patents involving C1QTNF5

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section


	EMD Millipore Custom Antibody & Bulk Services
	EMD Millipore Preclinical / Clinical Development Services
	EMD Millipore Immunoassay Services
	EMD Millipore Target Screening & Profiling Services

	Antibodies for C1QTNF5 (C1qTNF5)		Browse Cell Culture Products
	Browse ELISAs		Browse Flow Cytometry Kits
	Browse Primer Pairs		Browse Kinase Activity Assays/Reagents
	Browse ELISpot Kits/Development Modules		Browse TFB/Immunoprecipitation Assays
	Browse Apoptosis Detection Kits/Reagents		Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents
	Browse DNA Damage/Repair Kits/Reagents		Browse Multiplex/Array Assay Kits/Reagents
	Browse Cell Selection/Detection Kits/Reagents		Browse Secondary Antibodies/Controls/Staining Reagents
	Browse Phosphatase Activity Assays/Reagents		Browse Recombinant/Natural Proteins

	OriGene Antibodies for C1QTNF5		OriGene shRNA RFP for C1QTNF5
	OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for C1QTNF5		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C1QTNF5
	Browse OriGene Protein Over-expression Lysates		Browse OriGene Fluorogenic Cell Assay Kits
	OriGene siRNA for C1QTNF5		OriGene 3'-UTR Clone for C1QTNF5
	OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C1QTNF5		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C1QTNF5
	Browse OriGene GFP tagged cDNA clones in CMV expression vector		Browse OriGene MicroRNA Expression Plasmids
	Browse OriGene basic RS shRNAs		Browse OriGene validated miRNA SYBR primer pairs
	Browse OriGene full length recombinant human proteins expressed in human HEK293 cells		OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
	OriGene Custom Antibody Services for C1QTNF5		OriGene Custom Protein Services for C1QTNF5
	OriGene Custom Immunoassay Development

	QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat C1QTNF5
	QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing C1QTNF5
	QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C1QTNF5
	QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat C1QTNF5
	QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C1QTNF5
	QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C1QTNF5

	GenScript Custom Purified and Recombinant Proteins Services for C1QTNF5		GenScript cDNA clones with any tag delivered in your preferred vector for C1QTNF5
	GenScript Custom Assay Services for C1QTNF5		GenScript Custom Superior Antibodies Services for C1QTNF5
	GenScript Custom overexpressing Cell Line Services for C1QTNF5		CloneReady with Over 120,000 Genes
	Gene Synthesis: Any Gene in Any Vector		Vector-based siRNA and miRNA, Ready for Transfection
	Gene Mutant Library, Variants up to 10^11		Plasmid Preparation
	Custom Peptide Services

Search for Antibodies & Assays

	Regulatory tfbs in C1QTNF5 promoter
	Search Chromatin IP Primers for C1QTNF5
	Search RT² qPCR Primer Assays in human, mouse, rat C1QTNF5
	Search GNC Networks for C1QTNF5
	SABiosciences Custom PCR Arrays for C1QTNF5

Search Tocris compounds for C1QTNF5

	Browse Sino Biological Proteins and Antibodies
	Browse Sino Biological cDNA Clones
	Antibodies/Proteins Production Services
	Rabbit Monoclonal Antibody Platform
	Bulk Purchasing

	Assays/Proteins for C1QTNF5
	Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

	Novus Tissue Slides
	C1QTNF5 antibodies
	C1QTNF5 proteins
	C1QTNF5 lysates

	Antibodies for C1QTNF5
	See all of Abcam's Antibodies, Kits and Proteins for C1QTNF5
	Custom Antibody / Protein Production Service
	Bulk Purchasing
	Advantages of Rabbit Monoclonal antibodies
	Abcam protocols and scientific support

Browse ProSpec Recombinant Proteins

C1QTNF5 Proteins, Antibodies, CLIAs, and ELISAs

Search LifeMap BioReagents cell lines for C1QTNF5

	Gene Synthesis
	Protein Engineering
	Variant Library Synthesis
	Codon Optimization
	Protein Production and Purification

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C1QTNF5

	Browse SwitchGear 3'UTR luciferase reporter plasmids for C1QTNF5
	Browse SwitchGear Promoter luciferase reporter plasmids for C1QTNF5

ThermoFisher Antibodies for C1QTNF5

Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat C1QTNF5

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for C1QTNF5

Sirion Biotech Customized:

	stable knockdown cell line services for C1QTNF5
	inducible knockdown cell line services for C1QTNF5
	design and validation of potent shRNA sequences against C1QTNF5
	adenovirus for potent knockdown of C1QTNF5
	adenovirus for overexpression of C1QTNF5
	stable overexpressing cell line services for C1QTNF5
	inducible overexpressing cell line services for C1QTNF5

GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 27 Apr 2013 , 14 May 2013

View Random Gene

Category			VWF (GIFTS: 73) von Willebrand factor
GIFtS Group

The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes Disease genes C1QTNF5 gene at Home site.

hostname: 356977-web1.xennexinc.com index build: 106 solr: 1.4

Advanced Search

Export list of displayed genes

C1QTNF5 Gene

C1q and tumor necrosis factor related protein 5

Aliases
for C1QTNF5 gene

Summaries
for C1QTNF5 gene

Genomic Views
for C1QTNF5 gene

Proteins
for C1QTNF5 gene

Protein Domains /
Families
for C1QTNF5 gene

Function
for C1QTNF5 gene

Pathways & Interactions
for C1QTNF5 gene

Drugs & Compounds
for C1QTNF5 gene

Transcripts
for C1QTNF5 gene

Expression
for C1QTNF5 gene

Orthologs
for C1QTNF5 gene

Paralogs
for C1QTNF5 gene

Genomic Variants
for C1QTNF5 gene

Disorders / Diseases
for C1QTNF5 gene

Publications
for C1QTNF5 gene

External Searches for C1QTNF5 gene

Genome Databases showing C1QTNF5 gene

Other Databases showing C1QTNF5 gene

Specialized Databases showing C1QTNF5 gene

Intellectual Property
for C1QTNF5 gene

Products
for C1QTNF5 gene

View Random Gene

Advanced Search

Export list of displayed genes

C1QTNF5 Gene

C1q and tumor necrosis factor related protein 5

Aliasesfor C1QTNF5 gene

Summariesfor C1QTNF5 gene

Genomic Viewsfor C1QTNF5 gene

Proteinsfor C1QTNF5 gene

Protein Domains /Familiesfor C1QTNF5 gene

Functionfor C1QTNF5 gene

Pathways & Interactionsfor C1QTNF5 gene

Drugs & Compoundsfor C1QTNF5 gene

Transcriptsfor C1QTNF5 gene

Expression for C1QTNF5 gene

Orthologsfor C1QTNF5 gene

Paralogsfor C1QTNF5 gene

Genomic Variantsfor C1QTNF5 gene

Disorders / Diseasesfor C1QTNF5 gene

Publicationsfor C1QTNF5 gene

External Searches for C1QTNF5 gene

Genome Databases showing C1QTNF5 gene

Other Databases showing C1QTNF5 gene

Specialized Databases showing C1QTNF5 gene

Intellectual Propertyfor C1QTNF5 gene

Productsfor C1QTNF5 gene

View Random Gene

Aliases
for C1QTNF5 gene

Summaries
for C1QTNF5 gene

Genomic Views
for C1QTNF5 gene

Proteins
for C1QTNF5 gene

Protein Domains /
Families
for C1QTNF5 gene

Function
for C1QTNF5 gene

Pathways & Interactions
for C1QTNF5 gene

Drugs & Compounds
for C1QTNF5 gene

Transcripts
for C1QTNF5 gene

Expression
for C1QTNF5 gene

Orthologs
for C1QTNF5 gene

Paralogs
for C1QTNF5 gene

Genomic Variants
for C1QTNF5 gene

Disorders / Diseases
for C1QTNF5 gene

Publications
for C1QTNF5 gene

Intellectual Property
for C1QTNF5 gene

Products
for C1QTNF5 gene