Free for academic non-profit institutions. Other users need a Commercial license

Aliases for C1QTNF2 Gene

Aliases for C1QTNF2 Gene

  • C1q And Tumor Necrosis Factor Related Protein 2 2 3
  • CTRP2 3 4
  • Complement-C1q Tumor Necrosis Factor-Related Protein 2 3
  • Zacrp2 3

External Ids for C1QTNF2 Gene

Previous GeneCards Identifiers for C1QTNF2 Gene

  • GC05M159893
  • GC05M159710
  • GC05M159755
  • GC05M159707
  • GC05M154868

Summaries for C1QTNF2 Gene

GeneCards Summary for C1QTNF2 Gene

C1QTNF2 (C1q And Tumor Necrosis Factor Related Protein 2) is a Protein Coding gene. GO annotations related to this gene include identical protein binding and receptor binding. An important paralog of this gene is COL8A1.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C1QTNF2 Gene

Genomics for C1QTNF2 Gene

Regulatory Elements for C1QTNF2 Gene

Genomic Location for C1QTNF2 Gene

160,347,751 bp from pter
160,370,652 bp from pter
22,902 bases
Minus strand

Genomic View for C1QTNF2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for C1QTNF2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C1QTNF2 Gene

Proteins for C1QTNF2 Gene

  • Protein details for C1QTNF2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Complement C1q tumor necrosis factor-related protein 2
    Protein Accession:

    Protein attributes for C1QTNF2 Gene

    285 amino acids
    Molecular mass:
    29952 Da
    Quaternary structure:
    • May interact with FAM132B.
    • Sequence=AAH11699.2; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAH54506.2; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for C1QTNF2 Gene

Proteomics data for C1QTNF2 Gene at MOPED

Post-translational modifications for C1QTNF2 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C1QTNF2 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C1QTNF2 Gene

Domains & Families for C1QTNF2 Gene

Protein Domains for C1QTNF2 Gene

Suggested Antigen Peptide Sequences for C1QTNF2 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 C1q domain.
  • Contains 1 C1q domain.
  • Contains 1 collagen-like domain.
genes like me logo Genes that share domains with C1QTNF2: view

No data available for Gene Families for C1QTNF2 Gene

Function for C1QTNF2 Gene

Gene Ontology (GO) - Molecular Function for C1QTNF2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005102 receptor binding IEA --
GO:0005515 protein binding IPI 25416956
GO:0042802 identical protein binding IEA --
genes like me logo Genes that share ontologies with C1QTNF2: view

Phenotypes for C1QTNF2 Gene

GenomeRNAi human phenotypes for C1QTNF2:
genes like me logo Genes that share phenotypes with C1QTNF2: view

Animal Model Products

miRNA for C1QTNF2 Gene

miRTarBase miRNAs that target C1QTNF2

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targets and HOMER Transcription for C1QTNF2 Gene

Localization for C1QTNF2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for C1QTNF2 Gene


Subcellular locations from

Jensen Localization Image for C1QTNF2 Gene COMPARTMENTS Subcellular localization image for C1QTNF2 gene
Compartment Confidence
extracellular 2

Gene Ontology (GO) - Cellular Components for C1QTNF2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005581 collagen trimer IEA --
GO:0005615 extracellular space IEA --
genes like me logo Genes that share ontologies with C1QTNF2: view

Pathways & Interactions for C1QTNF2 Gene

SuperPathways for C1QTNF2 Gene

No Data Available

Gene Ontology (GO) - Biological Process for C1QTNF2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000187 activation of MAPK activity IEA --
GO:0045725 positive regulation of glycogen biosynthetic process IEA --
GO:0046321 positive regulation of fatty acid oxidation IEA --
GO:0046326 positive regulation of glucose import IEA --
GO:0051260 protein homooligomerization IEA --
genes like me logo Genes that share ontologies with C1QTNF2: view

No data available for Pathways by source and SIGNOR curated interactions for C1QTNF2 Gene

Drugs & Compounds for C1QTNF2 Gene

No Compound Related Data Available

Transcripts for C1QTNF2 Gene

mRNA/cDNA for C1QTNF2 Gene

Unigene Clusters for C1QTNF2 Gene

C1q and tumor necrosis factor related protein 2:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for C1QTNF2 Gene

No ASD Table

Relevant External Links for C1QTNF2 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C1QTNF2 Gene

mRNA expression in normal human tissues for C1QTNF2 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for C1QTNF2 Gene

This gene is overexpressed in Artery - Aorta (x6.9), Artery - Coronary (x4.3), and Artery - Tibial (x4.1).

Protein differential expression in normal tissues from HIPED for C1QTNF2 Gene

This gene is overexpressed in Tlymphocyte (39.2), Monocytes (14.6), and Blymphocyte (8.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for C1QTNF2 Gene

SOURCE GeneReport for Unigene cluster for C1QTNF2 Gene Hs.110062

genes like me logo Genes that share expression patterns with C1QTNF2: view

Protein tissue co-expression partners for C1QTNF2 Gene

Primer Products

In Situ Assay Products

No data available for mRNA Expression by UniProt/SwissProt for C1QTNF2 Gene

Orthologs for C1QTNF2 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C1QTNF2 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia C1QTNF2 35
  • 89.47 (n)
  • 94.04 (a)
C1QTNF2 36
  • 94 (a)
(Canis familiaris)
Mammalia C1QTNF2 35
  • 90.76 (n)
  • 97.19 (a)
C1QTNF2 36
  • 97 (a)
(Mus musculus)
Mammalia C1qtnf2 35
  • 88 (n)
  • 94.12 (a)
C1qtnf2 16
C1qtnf2 36
  • 93 (a)
(Pan troglodytes)
Mammalia C1QTNF2 35
  • 98.99 (n)
  • 98.79 (a)
C1QTNF2 36
  • 99 (a)
(Rattus norvegicus)
Mammalia C1qtnf2 35
  • 86.51 (n)
  • 93.77 (a)
(Monodelphis domestica)
Mammalia C1QTNF2 36
  • 76 (a)
(Ornithorhynchus anatinus)
Mammalia C1QTNF2 36
  • 84 (a)
(Gallus gallus)
Aves C1QTNF2 35
  • 72.65 (n)
  • 80.28 (a)
C1QTNF2 36
  • 79 (a)
(Anolis carolinensis)
Reptilia C1QTNF2 36
  • 75 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100490036 35
  • 66.07 (n)
  • 74.29 (a)
(Danio rerio)
Actinopterygii c1qtnf2 35
  • 63.47 (n)
  • 70.11 (a)
c1qtnf2 36
  • 64 (a)
Species with no ortholog for C1QTNF2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C1QTNF2 Gene

Gene Tree for C1QTNF2 (if available)
Gene Tree for C1QTNF2 (if available)

Paralogs for C1QTNF2 Gene

(9) SIMAP similar genes for C1QTNF2 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with C1QTNF2: view

Variants for C1QTNF2 Gene

Structural Variations from Database of Genomic Variants (DGV) for C1QTNF2 Gene

Variant ID Type Subtype PubMed ID
esv2730977 CNV Deletion 23290073

Variation tolerance for C1QTNF2 Gene

Residual Variation Intolerance Score: 46.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.06; 37.83% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C1QTNF2 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations from dbSNP and Humsavar for C1QTNF2 Gene

Disorders for C1QTNF2 Gene

Relevant External Links for C1QTNF2

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with C1QTNF2: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C1QTNF2 Gene

Publications for C1QTNF2 Gene

  1. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 67
  2. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 67
  3. Weight loss after gastric bypass is associated with a variant at 15q26.1. (PMID: 23643386) Hatoum I.J. … Kaplan L.M. (Am. J. Hum. Genet. 2013) 67
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 67
  5. The DNA sequence and comparative analysis of human chromosome 5. (PMID: 15372022) Schmutz J. … Rubin E.M. (Nature 2004) 67

Products for C1QTNF2 Gene

Sources for C1QTNF2 Gene

Back to Top