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C1QTNF1 Gene

protein-coding   GIFtS: 59
GCID: GC17P077020

C1q And Tumor Necrosis Factor Related Protein 1

  Search for C1QTNF1
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
C1q And Tumor Necrosis Factor Related Protein 11 2     CTRP12 3
GIP2 3 5     ZSIG372
G Protein Coupled Receptor Interacting Protein1 2     Complement C1q Tumor Necrosis Factor-Related Protein 12
G Protein-Coupled Receptor-Interacting Protein2 3     

External Ids:    HGNC: 143241   Entrez Gene: 1148972   Ensembl: ENSG000001739187   OMIM: 6103655   UniProtKB: Q9BXJ13   

Export aliases for C1QTNF1 gene to outside databases

Previous GC identifers: GC17U990301 GC17M080159 GC17P077481 GC17P077627 GC17P077617 GC17P074531 GC17P072443


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for C1QTNF1 Gene:
C1QTNF1 (C1q and tumor necrosis factor related protein 1) is a protein-coding gene. An important paralog of this gene is C1QTNF6.

Gene Wiki entry for C1QTNF1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000017.10  NT_010783.16  NC_018928.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the C1QTNF1 gene promoter:
         Sp1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 3): C1QTNF1 promoter sequence
   Search Chromatin IP Primers for C1QTNF1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat C1QTNF1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q25.3   Ensembl cytogenetic band:  17q25.3   HGNC cytogenetic band: 17q25

C1QTNF1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
C1QTNF1 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17P077020:  view genomic region     (about GC identifiers)

Start:
77,018,896 bp from pter      End:
77,045,870 bp from pter
Size:
26,975 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: C1QT1_HUMAN, Q9BXJ1 (See protein sequence)
Recommended Name: Complement C1q tumor necrosis factor-related protein 1 precursor  
Size: 281 amino acids; 31743 Da
Sequence caution: Sequence=AAG44303.1; Type=Erroneous initiation; Sequence=CAC20425.1; Type=Erroneous initiation;
Secondary accessions: Q96NF2 Q9GZR4

Explore the universe of human proteins at neXtProt for C1QTNF1: NX_Q9BXJ1

Explore proteomics data for C1QTNF1 at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn93
  • Modification sites at PhosphoSitePlus

  • See C1QTNF1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (4 alternative transcripts): 
    NP_112230.1  NP_699203.1  NP_940995.1  NP_940996.1  

    ENSEMBL proteins: 
     ENSP00000463337   ENSP00000462990   ENSP00000463922   ENSP00000340864   ENSP00000311265  
     ENSP00000376240   ENSP00000462481   ENSP00000463008   ENSP00000463108   ENSP00000343230  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    3 InterPro protein domains:
     IPR008983 Tumour_necrosis_fac-like_dom
     IPR008160 Collagen
     IPR001073 C1q

    Graphical View of Domain Structure for InterPro Entry Q9BXJ1

    ProtoNet protein and cluster: Q9BXJ1

    3 Blocks protein domains:
    IPB001073 Complement C1q protein
    IPB008160 Collagen triple helix repeat
    IPB008161 Collagen helix repeat


    UniProtKB/Swiss-Prot: C1QT1_HUMAN, Q9BXJ1
    Similarity: Contains 1 C1q domain
    Similarity: Contains 1 collagen-like domain


    Find genes that share domains with C1QTNF1           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI12409230
    GO:0005518collagen binding IDA16195328
         
    Find genes that share ontologies with C1QTNF1           About GenesLikeMe


    Phenotypes:
         2 GenomeRNAi human phenotypes for C1QTNF1:
     Increased cell number in S and  Increased gamma-H2AX phosphory 

         1 MGI phenotypic allele for C1qtnf1 (no phenotypes)

    Find genes that share phenotypes with C1QTNF1           About GenesLikeMe

    Animal Models:
         MGI mouse knock-out C1qtnf1tm1Lex for C1QTNF1

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for C1QTNF1
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for C1QTNF1
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for C1QTNF1

    miRNA
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    hsa-mir-335-5p (MIRT019162), hsa-mir-26b-5p (MIRT030279)

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    7 qRT-PCR Assays for microRNAs that regulate C1QTNF1:
    hsa-miR-33a* hsa-miR-4307 hsa-miR-875-3p hsa-miR-1276 hsa-miR-298 hsa-miR-409-3p hsa-miR-1299
    SwitchGear 3'UTR luciferase reporter plasmidC1QTNF1 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat C1QTNF1

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C1QTNF1


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    C1QT1_HUMAN, Q9BXJ1: Secreted (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    extracellular3
    cytosol1
    lysosome1
    nucleus1

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005581collagen IEA--
    GO:0005615extracellular space IDA18171693
    GO:0005887integral component of plasma membrane IDA12409230

    Find genes that share ontologies with C1QTNF1           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for C1QTNF1
    Interactions:

        Search GeneGlobe Interaction Network for C1QTNF1

    STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

    5 Interacting proteins for C1QTNF1 (Q9BXJ13 ENSP000003408644) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    AVPR2P305183, ENSP000003380724I2D: score=2 STRING: ENSP00000338072
    UBQLN4Q9NRR53, ENSP000003572924I2D: score=2 STRING: ENSP00000357292
    SGTAO437653, ENSP000002215664I2D: score=3 STRING: ENSP00000221566
    CACNA1AO005553I2D: score=1 
    SUGT1ENSP000003672084STRING: ENSP00000367208
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 10):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007204positive regulation of cytosolic calcium ion concentration IDA18171693
    GO:0010544negative regulation of platelet activation IDA16195328
    GO:0010628positive regulation of gene expression IDA18171693
    GO:0010906regulation of glucose metabolic process IEA--
    GO:0043410positive regulation of MAPK cascade IEA--

    Find genes that share ontologies with C1QTNF1           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for C1QTNF1 (C1QT1)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for C1QTNF1 gene (4 alternative transcripts): 
    NM_030968.3  NM_153372.1  NM_198593.3  NM_198594.2  

    Unigene Cluster for C1QTNF1:

    C1q and tumor necrosis factor related protein 1
    Hs.201398  [show with all ESTs]
    Unigene Representative Sequence: AY358424
    12 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000578229 ENST00000580454 ENST00000579760 ENST00000582295 ENST00000339142(uc002jwp.3 uc002jwq.3)
    ENST00000311661 ENST00000392445(uc002jwr.4) ENST00000581774 ENST00000583904
    ENST00000580474 ENST00000582625 ENST00000354124
    miRNA
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    7 qRT-PCR Assays for microRNAs that regulate C1QTNF1:
    hsa-miR-33a* hsa-miR-4307 hsa-miR-875-3p hsa-miR-1276 hsa-miR-298 hsa-miR-409-3p hsa-miR-1299
    SwitchGear 3'UTR luciferase reporter plasmidC1QTNF1 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for C1QTNF1
    Predesigned siRNA for gene silencing in human, mouse, rat C1QTNF1
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    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 3): C1QTNF1 (NM_198594)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C1QTNF1
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    OriGene qPCR primer pairs and template standards for C1QTNF1
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    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat C1QTNF1
      QuantiTect SYBR Green Assays in human, mouse, rat C1QTNF1
      QuantiFast Probe-based Assays in human, mouse, rat C1QTNF1

    Additional mRNA sequence: 

    AF329840.1 AK055541.1 AK075175.1 AK172767.1 AK292034.1 AY358424.1 BC021553.1 NR_049769.1 

    15 DOTS entries:

    DT.441684  DT.100700668  DT.95203169  DT.91758423  DT.100818299  DT.101984250  DT.100028802  DT.100818295 
    DT.121012903  DT.95203153  DT.97844525  DT.97844528  DT.100818294  DT.121012907  DT.92016169 

    Selected AceView cDNA sequences (see all 177):

    BU753652 BQ668700 CD742981 CR612304 C18539 AI066402 NM_198593 AW519177 
    NM_030968 BM708441 BM544179 CA415378 C00999 AW469083 BU730760 CA446411 
    AL043828 BX339524 AI682301 AA631689 AI460198 NM_198594 BU679665 BM723520 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for C1QTNF1 (see all 10)    About this scheme

    ExUns: 1 ^ 2a · 2b · 2c ^ 3a · 3b ^ 4a · 4b ^ 5 ^ 6a · 6b · 6c ^ 7 ^ 8 ^ 9a · 9b · 9c · 9d · 9e · 9f · 9g
    SP1:                                                  -     -                       -                                             
    SP2:        -     -     -     -     -     -     -     -     -                       -                                             
    SP3:                                                        -                       -                                             
    SP4:                          -     -     -     -     -     -                       -                                             
    SP5:                                      -     -     -     -                       -                                             


    ECgene alternative splicing isoforms for C1QTNF1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    C1QTNF1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTGATGCCCA
    C1QTNF1 Expression
    About this image


    C1QTNF1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 4) fully expand
     
     Epithelial Cells
             Podocytes Podocyte Layer
     
     Kidney (Urinary System)
             Podocytes Podocyte Layer
     
     Adipose (Muscoskeletal System)
     
     Placenta (Extraembryonic Tissues)
    C1QTNF1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    C1QTNF1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.201398
        Custom PCR Arrays for C1QTNF1
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    QuantiTect SYBR Green Assays in human, mouse, rat C1QTNF1
    QuantiFast Probe-based Assays in human, mouse, rat C1QTNF1
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C1QTNF1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for C1QTNF1 gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia C1qtnf11 , 5 C1q and tumor necrosis factor related protein 11, 5 81.97(n)1
    77.58(a)1
      11 (83.17 cM)5
    567451  NM_001204129.11  NP_001191058.11 
     1184282035 
    chicken
    (Gallus gallus)
    Aves C1QTNF11 C1q and tumor necrosis factor related protein 1 77.17(n)
    75.63(a)
      768784  XM_004946289.1  XP_004946346.1 
    lizard
    (Anolis carolinensis)
    Reptilia C1QTNF16
    C1q and tumor necrosis factor related protein 1
    65(a)
    1 ↔ 1
    2(101674691-101685977)
    zebrafish
    (Danio rerio)
    Actinopterygii LOC1005380791 complement C1q tumor necrosis factor-related protein more 71.77(n)
    74.64(a)
      100538079  XM_003199627.2  XP_003199675.1 


    ENSEMBL Gene Tree for C1QTNF1 (if available)
    TreeFam Gene Tree for C1QTNF1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for C1QTNF1 gene
    C1QTNF62  C1QB2  COL10A12  C1QTNF9B2  C1QA2  C1QTNF42  COL8A22  C1QTNF92  
    C1QTNF52  COL8A12  OTOL12  C1QTNF82  C1QTNF72  C1QC2  C1QTNF22  ADIPOQ2  
    4 SIMAP similar genes for C1QTNF1 using alignment to 2 protein entries:     C1QT1_HUMAN (see all proteins):
    C1QTNF6    dJ151B14.4    C1QTNF8    ADIPOQ

    Find genes that share paralogs with C1QTNF1           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for C1QTNF1 (see all 739)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs2015056571,2
    Cuntested178125511(+) CCGGAC/TCATGC 3 D int1 syn10--------
    rs352430481,2
    C--77035866(+) TGTGT-/GT/TA 
            
    ATATA
    3 -- int10--------
    rs568049831,2
    C--77039735(+) GTGAC-/TGTGTGT 3 -- int10--------
    rs1905591741,2
    --78103652(+) CTGGGA/GTTAAA 2 -- us2k10--------
    rs786433241,2
    C--78103656(+) GATTAA/CAGGTG 2 -- us2k10--------
    rs1165390641,2
    C,F--78103719(+) TGTCCC/TGCTTT 2 -- us2k12Minor allele frequency- T:0.08WA NA 238
    rs1454232361,2
    --78103788(+) AAGAAG/TCCTTC 2 -- us2k10--------
    rs1171698681,2
    C,F--78103861(+) ATGGAC/TGAAGG 2 -- us2k11Minor allele frequency- T:0.03NA 120
    rs1816470861,2
    --78104029(+) AGCTTA/CTCTCT 2 -- us2k10--------
    rs1401740171,2
    --78104060(+) GCAACC/GAGGGA 2 -- us2k10--------

    HapMap Linkage Disequilibrium report for C1QTNF1 (77018896 - 77045870 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for C1QTNF1 (see all 11):    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv2156CNV Loss18451855
    nsv833556CNV Loss17160897
    nsv908903CNV Loss21882294
    dgv3284n71CNV Loss21882294
    nsv908900CNV Loss21882294
    dgv3285n71CNV Loss21882294
    nsv521186CNV Loss19592680
    nsv523650CNV Loss19592680
    nsv470610CNV Loss18288195
    nsv470611CNV Gain18288195

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 610365    OMIM disorders: --


    Find genes that share disorders with C1QTNF1           About GenesLikeMe

    Genetic Association Database (GAD): C1QTNF1
    Human Genome Epidemiology (HuGE) Navigator: C1QTNF1 (1 document)

    Export disorders for C1QTNF1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for C1QTNF1 gene, integrated from 10 sources (see all 20):
    (articles sorted by number of sources associating them with C1QTNF1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Association between the SERPING1 gene and age-related macular degeneration: a two-stage case-control study. (PubMed id 18842294)1, 4 Ennis S....Lotery A. (Lancet 2008)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    4. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (Genome Res. 2003)
    5. GIP, a G-protein-coupled receptor interacting protein. (PubMed id 12409230)1, 3 Innamorati G....Birnbaumer M. (Regul. Pept. 2002)
    6. Development of a novel enzyme-linked immunosorbent assay (ELISA) for measurement of serum CTRP1: a pilot study: measurement of serum CTRP1 in healthy donors and patients with metabolic syndrome. (PubMed id 23000311)1 Chalupova L....Adamcova K. (Clin. Biochem. 2013)
    7. Comparison of an expanded ataxia interactome with patient medical records reveals a relationship between macular degeneration and ataxia. (PubMed id 21078624)1 Kahle J.J....Zoghbi H.Y. (Hum. Mol. Genet. 2011)
    8. Molecular, biochemical and functional characterizations of C1q/TNF family members: adipose-tissue-selective expression patterns, regulation by PPAR-gamma agonist, cysteine-mediated oligomerizations, combinatorial associations and metabolic functions. (PubMed id 18783346)1 Wong G.W....Lodish H.F. (Biochem. J. 2008)
    9. A novel adipokine CTRP1 stimulates aldosterone production. (PubMed id 18171693)1 Jeon J.H....Yang Y. (FASEB J. 2008)
    10. Tumor necrosis factor-alpha and interleukin-1beta increases CTRP1 expression in adipose tissue. (PubMed id 16806199)1 Kim K.Y....Yang Y. (FEBS Lett. 2006)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 114897 HGNC: 14324 AceView: C1QTNF1 Ensembl:ENSG00000173918 euGenes: HUgn114897
    ECgene: C1QTNF1 H-InvDB: C1QTNF1

    (According to HUGE)
    About This Section

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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for C1QTNF1 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for C1QTNF1 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for C1QTNF1 gene:
    Search GeneIP for patents involving C1QTNF1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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