Aliases for C1QC Gene
Aliases for C1QC Gene
External Ids for C1QC Gene
- HGNC: 1245
- Entrez Gene: 714
- Ensembl: ENSG00000159189
- OMIM: 120575
- UniProtKB: P02747
Previous HGNC Symbols for C1QC Gene
- C1QG
Previous GeneCards Identifiers for C1QC Gene
- GC01P022842
- GC01P022970
- GC01P021214
Summaries for C1QC Gene
-
This gene encodes the C-chain polypeptide of serum complement subcomponent C1q, which associates with C1r and C1s to yield the first component of the serum complement system. C1q is composed of 18 polypeptide chains which include 6 A-chains, 6 B-chains, and 6 C-chains. Each chain contains an N-terminal collagen-like region and a C-terminal C1q globular domain. C1q deficiency is associated with lupus erythematosus and glomerulonephritis. [provided by RefSeq, Dec 2016]
GeneCards Summary for C1QC Gene
C1QC (Complement C1q C Chain) is a Protein Coding gene. Diseases associated with C1QC include C1q Deficiency and Immunodeficiency Due To A Classical Component Pathway Complement Deficiency. Among its related pathways are Creation of C4 and C2 activators and Toll-like receptor signaling pathway. An important paralog of this gene is C1QB.
UniProtKB/Swiss-Prot for C1QC Gene
-
C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes.
Additional gene information for C1QC Gene
- Monarch Initiative
- Search for C1QC at DataMed
- Search for C1QC at HumanCyc
No data available for CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C1QC Gene
Genomics for C1QC Gene
GeneHancer (GH) Regulatory Elements for C1QC Gene
GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
---|---|---|---|---|---|---|---|---|---|---|
GH01I022643 | Promoter | 0.7 | EPDnew | 550.8 | 0.0 | -11 | 0.1 | MAFG MAFK EMSY | C1QC C1QA | |
GH01I022412 | Enhancer | 1.2 | Ensembl ENCODE | 11.9 | -229.8 | -229805 | 2.6 | PKNOX1 CLOCK ATF1 FOXA2 MLX ARID4B NEUROD1 SIN3A ZNF48 YY1 | C1QC C1QA LACTBL1 ZBTB40 LOC105376856 ENSG00000279625 | |
GH01I022416 | Enhancer | 1.1 | Ensembl ENCODE | 11.9 | -226.9 | -226879 | 0.5 | ATF1 ARID4B SIN3A ZNF2 ZNF48 ARID2 ZNF143 ATF7 KLF13 DEK | C1QA C1QC LACTBL1 LOC105376856 ENSG00000279625 | |
GH01I023548 | Enhancer | 1.1 | Ensembl ENCODE dbSUPER | 5.1 | +905.4 | 905425 | 0.9 | HDAC1 BCOR HDGF ZBTB6 ZMYM3 NFXL1 ZFHX2 CTBP1 EGR1 PHF20 | ZNF436-AS1 TCEA3 C1QC LOC105376859 E2F2 | |
GH01I022851 | Enhancer | 0.2 | FANTOM5 | 2.2 | +208.1 | 208074 | 0.2 | C1QA C1QB C1QC ENSG00000225952 MIR4253 EPHB2 |
- Top Transcription factor binding sites by QIAGEN in the C1QC gene promoter:
Regulatory Element Products
Genomic Locations for C1QC Gene
- chr1:22,643,625-22,648,110
- (GRCh38/hg38)
- Size:
- 4,486 bases
- Orientation:
- Plus strand
- chr1:22,970,118-22,974,603
- (GRCh37/hg19)
Genomic View for C1QC Gene
- Cytogenetic band:
-
- 1p36.12 by Ensembl
- 1p36.12 by Entrez Gene
- 1p36.12 by HGNC


RefSeq DNA sequence for C1QC Gene
Proteins for C1QC Gene
-
Protein details for C1QC Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P02747-C1QC_HUMAN
- Recommended name:
- Complement C1q subcomponent subunit C
- Protein Accession:
- P02747
- Q7Z502
- Q96DL2
- Q96H05
Protein attributes for C1QC Gene
- Size:
- 245 amino acids
- Molecular mass:
- 25774 Da
- Quaternary structure:
-
- C1 is a calcium-dependent trimolecular complex of C1q, R and S in the molar ration of 1:2:2. C1q subcomponent is composed of nine subunits, six of which are disulfide-linked dimers of the A and B chains, and three of which are disulfide-linked dimers of the C chain.
Protein Expression for C1QC Gene
Post-translational modifications for C1QC Gene
- O-linked glycans consist of Glc-Gal disaccharides bound to the oxygen atom of post-translationally added hydroxyl groups.
- Glycosylation at Lys75
Other Protein References for C1QC Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- R&D Systems Antibodies for C1QC (Complement Component C1qC)
-
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Protein Products
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-
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Assay Products
No data available for DME Specific Peptides for C1QC Gene
Domains & Families for C1QC Gene
Gene Families for C1QC Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Disease related genes
- Plasma proteins
- Predicted secreted proteins
Protein Domains for C1QC Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for C1QC Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
No data available for UniProtKB/Swiss-Prot for C1QC Gene
Function for C1QC Gene
Molecular function for C1QC Gene
- UniProtKB/Swiss-Prot Function:
- C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0004252 | serine-type endopeptidase activity | TAS | -- |
GO:0005515 | protein binding | IPI | 28018340 |
Phenotypes for C1QC Gene
- GenomeRNAi human phenotypes for C1QC:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
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-
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-
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- Overview of 113 available C1QC gene related products
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- Overview of 113 available C1QC gene related products
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Clone Products
- Sino Biological Human cDNA Clone for C1QC
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-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for C1QC
-
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Cell Line Products
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Horizon Cell Lines for C1QC
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No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for C1QC Gene
Localization for C1QC Gene
Subcellular locations from UniProtKB/Swiss-Prot for C1QC Gene
- Secreted.
- Vesicles (1)
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005576 | extracellular region | TAS | -- |
GO:0005581 | collagen trimer | IEA | -- |
GO:0005615 | extracellular space | HDA,IDA | 22664934 |
GO:0070062 | extracellular exosome | HDA,IDA | 23376485 |
GO:0072562 | blood microparticle | HDA,IDA | 22516433 |
Pathways & Interactions for C1QC Gene
SuperPathway | Contained pathways | ||
---|---|---|---|
1 | Complement Pathway | ||
2 | Creation of C4 and C2 activators | ||
3 | Complement and coagulation cascades | ||
4 | Innate Immune System |
.61
|
|
5 | Toll-like receptor signaling pathway |
Pathways by source for C1QC Gene
1 Sino Biological pathway for C1QC Gene
2 BioSystems pathways for C1QC Gene
6 Reactome pathways for C1QC Gene
6 KEGG pathways for C1QC Gene
1 GeneGo (Thomson Reuters) pathway for C1QC Gene
2 Qiagen pathways for C1QC Gene
Interacting Proteins for C1QC Gene
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0006508 | proteolysis | IEA | -- |
GO:0006955 | immune response | NAS | 9777412 |
GO:0006956 | complement activation | TAS | -- |
GO:0006958 | complement activation, classical pathway | TAS,IEA | -- |
GO:0030449 | regulation of complement activation | TAS | -- |
No data available for SIGNOR curated interactions for C1QC Gene
Drugs & Compounds for C1QC Gene
Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
---|---|---|---|---|---|---|
Abciximab | Approved | Pharma | Target | 65 | ||
Adalimumab | Approved | Pharma | Target | 521 | ||
Alefacept | Approved, Investigational, Withdrawn | Pharma | Target | 40 | ||
alemtuzumab | Approved, Investigational | Pharma | Target | Therapeutic Antibodies | 319 | |
Basiliximab | Approved, Investigational | Pharma | Target | 140 |
Transcripts for C1QC Gene
mRNA/cDNA for C1QC Gene
- (4) REFSEQ mRNAs :
- (4) Additional mRNA sequences :
- (507) Selected AceView cDNA sequences:
- (3) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for C1QC Gene
CRISPR Products
-
OriGene CRISPR knockouts for C1QC
- genomics-online: gRNA clones - Search results for 113 available C1QC gene related products
- Overview of 113 available C1QC gene related products
- Applied Biological Materials CRISPR for C1QC
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for C1QC
- GenScript: Design CRISPR guide RNA sequences for C1QC
miRNA Products
- Search ViGene Biosciences for C1QC
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for C1QC
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- genomics-online: shRNA clones - Search results for 113 available C1QC gene related products
- Overview of 113 available C1QC gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for C1QC gene
Clone Products
- Sino Biological Human cDNA Clone for C1QC
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for C1QC
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for C1QC
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for C1QC
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
ExUns: | 1a | · | 1b | · | 1c | · | 1d | · | 1e | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SP1: | - | - | |||||||||||||||
SP2: | - | - | - | - | |||||||||||||
SP3: | |||||||||||||||||
SP4: | - | ||||||||||||||||
SP5: |
Expression for C1QC Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Skeletal Muscle (Muscoskeletal System)
-
Kidney (Urinary System)
- Metanephric Mesenchyme Cells Metanephric Mesenchyme
-
Lateral Plate Mesoderm (Gastrulation Derivatives)
- Hematopoietic Stem Cells Aorta-Gonad-Mesonephros
-
Blood (Cardiovascular System)
- Hematopoietic Stem Cells Aorta-Gonad-Mesonephros
-
Eye (Sensory Organs)
- Adult Retinal Pigmented Epithelium Cells Retinal Pigmented Epithelium
-
Epithelial Cells
- Adult Retinal Pigmented Epithelium Cells Retinal Pigmented Epithelium
- Brain (Nervous System)
- Intestine (Gastrointestinal Tract)
-
Colon (Gastrointestinal Tract)
-
Placenta (Extraembryonic Tissues)
-
Spleen (Hematopoietic System)
-
Gall Bladder (Hepatobiliary System)
-
Lung (Respiratory System)
-
Adrenal Gland (Endocrine System)
-
Stomach (Gastrointestinal Tract)
-
Liver (Hepatobiliary System)
-
Adipose (Muscoskeletal System)
mRNA differential expression in normal tissues according to GTEx for C1QC Gene
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for C1QC Gene
NURSA nuclear receptor signaling pathways regulating expression of C1QC Gene:
C1QCSOURCE GeneReport for Unigene cluster for C1QC Gene:
Hs.467753Evidence on tissue expression from TISSUES for C1QC Gene
- Nervous system(4.5)
- Blood(4.2)
- Lung(3.1)
- Spleen(2.9)
- Liver(2.3)
- Lymph node(2.3)
- Intestine(2.1)
- Adrenal gland(2)
- Gall bladder(2)
Phenotype-based relationships between genes and organs from Gene ORGANizer for C1QC Gene
- ectoderm
- endoderm
- mesoderm
- cardiovascular
- digestive
- endocrine
- immune
- integumentary
- lymphatic
- nervous
- respiratory
- skeletal muscle
- skeleton
- urinary
- brain
- cheek
- ear
- eye
- face
- head
- lip
- meninges
- mouth
- neck
- scalp
- thyroid
- bronchus
- esophagus
- heart
- lung
- intestine
- kidney
- large intestine
- liver
- pancreas
- small intestine
- spleen
- stomach
- ankle
- digit
- elbow
- finger
- foot
- hand
- hip
- knee
- lower limb
- shoulder
- toe
- upper limb
- wrist
- blood
- blood vessel
- coagulation system
- lymph node
- skin
- white blood cell
Primer Products
-
OriGene qPCR primer pairs and template standards for C1QC
-
OriGene qPCR primer pairs for C1QC
- genomics-online: primer clones - Search results for 113 available C1QC gene related products
- Overview of 113 available C1QC gene related products
No data available for mRNA Expression by UniProt/SwissProt for C1QC Gene
Orthologs for C1QC Gene
This gene was present in the common ancestor of chordates.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
chimpanzee (Pan troglodytes) |
Mammalia | C1QC 33 34 |
|
||
dog (Canis familiaris) |
Mammalia | C1QC 33 34 |
|
||
cow (Bos Taurus) |
Mammalia | C1QC 33 34 |
|
||
rat (Rattus norvegicus) |
Mammalia | C1qc 33 |
|
||
mouse (Mus musculus) |
Mammalia | C1qc 33 16 34 |
|
||
oppossum (Monodelphis domestica) |
Mammalia | C1QC 34 |
|
OneToOne | |
platypus (Ornithorhynchus anatinus) |
Mammalia | -- 34 |
|
OneToMany | |
-- 34 |
|
OneToMany | |||
chicken (Gallus gallus) |
Aves | C1QC 33 |
|
||
zebrafish (Danio rerio) |
Actinopterygii | c1qc 33 34 |
|
- Species where no ortholog for C1QC was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- lizard (Anolis carolinensis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for C1QC Gene
Paralogs for C1QC Gene
(11) SIMAP similar genes for C1QC Gene using alignment to 1 proteins:
Variants for C1QC Gene
SNP ID | Clin | Chr 01 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
rs200206736 | pathogenic, C1q deficiency, Complement component C1q deficiency (C1QD) [MIM:613652] | 22,644,123(+) | G/A | coding_sequence_variant, missense_variant | |
rs377549148 | pathogenic, C1q deficiency | 22,647,250(+) | C/T | coding_sequence_variant, stop_gained | |
rs752596663 | pathogenic, C1q deficiency | 22,647,535(+) | G/A | coding_sequence_variant, missense_variant | |
rs761681612 | pathogenic, C1q deficiency | 22,647,256(+) | CCC/CC | coding_sequence_variant, frameshift | |
rs1000071806 | -- | 22,642,776(+) | C/A | upstream_transcript_variant |
Additional Variant Information for C1QC Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C1QC Gene
Disorders for C1QC Gene

(8) MalaCards diseases for C1QC Gene - From: HGMD, OMIM, ClinVar, GTR, Orphanet, Swiss-Prot, DISEASES, and GeneCards
Disorder | Aliases | PubMed IDs |
---|---|---|
c1q deficiency |
|
|
immunodeficiency due to a classical component pathway complement deficiency |
|
|
glomerulonephritis |
|
|
lupus erythematosus |
|
|
rothmund-thomson syndrome |
|
|
UniProtKB/Swiss-Prot
C1QC_HUMAN- Complement component C1q deficiency (C1QD) [MIM:613652]: A disorder caused by impaired activation of the complement classical pathway. It generally leads to severe immune complex disease with features of systemic lupus erythematosus and glomerulonephritis. {ECO:0000269 PubMed:8630118}. Note=The disease is caused by mutations affecting the gene represented in this entry.
Additional Disease Information for C1QC
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No data available for Genatlas for C1QC Gene
Publications for C1QC Gene
- Characterization and organization of the genes encoding the A-, B- and C-chains of human complement subcomponent C1q. The complete derived amino acid sequence of human C1q. (PMID: 1706597) Sellar GC … Reid KB (The Biochemical journal 1991) 2 3 4 58
- Risk of meningioma and common variation in genes related to innate immunity. (PMID: 20406964) Rajaraman P … Inskip PD (Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2010) 3 44 58
- Polymorphisms in innate immunity genes and risk of childhood leukemia. (PMID: 20438785) Han S … Kang D (Human immunology 2010) 3 44 58
- Assessing association of common variation in the C1Q gene cluster with systemic lupus erythematosus. (PMID: 20528885) Rafiq S … Eggleton P (Clinical and experimental immunology 2010) 3 44 58
- Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PMID: 20628086) Bailey SD … DREAM investigators (Diabetes care 2010) 3 44 58
Products for C1QC Gene
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- Invitrogen Antibodies for C1QC
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- VectorBuilder custom plasmid, inducible vectors for C1QC
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for C1QC
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- antibodies-online: Search results for 54 available C1QC Antibodies ranked by validation data
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- antibodies-online: Search results for 15 available C1QC Elisa Kits ranked by validation data
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- antibodies-online: Search results for 4 available C1QC Proteins ranked by validation data
- Compare Top C1QC Proteins
- Search GeneTex for Antibodies for C1QC
- Search GeneTex for Proteins for C1QC
- ViGene Biosciences adenoviral particle packaged cDNA for C1QC gene
- ViGene Biosciences lentiviral particle packaged cDNA for C1QC gene
- ViGene Biosciences ready-to-package AAV shRNAs for C1QC gene
- Search ViGene Biosciences for C1QC
- Santa Cruz Biotechnology (SCBT) Antibodies for C1QC
- Search Santa Cruz Biotechnology (SCBT) for C1QC siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for C1QC
- Horizon Cell Lines for C1QC
- genomics-online: cdna clones - Search results for 113 available C1QC gene related products
- Overview of 113 available C1QC gene related products
- orf clones - Search results for 113 available C1QC gene related products
- Overview of 113 available C1QC gene related products
- genomics-online: gRNA clones - Search results for 113 available C1QC gene related products
- Overview of 113 available C1QC gene related products
- genomics-online: primer clones - Search results for 113 available C1QC gene related products
- Overview of 113 available C1QC gene related products
- genomics-online: shRNA clones - Search results for 113 available C1QC gene related products
- Overview of 113 available C1QC gene related products
Sources for C1QC Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew