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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

C1D Gene

protein-coding   GIFtS: 56
GCID: GC02M068180

C1D Nuclear Receptor Corepressor

(Previous name: C1D nuclear receptor co-repressor)
Microbiology & Infectious Diseases Congress
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
C1D Nuclear Receptor Corepressor1 2     SUN-CoR2
C1D Nuclear Receptor Co-Repressor1 2     C1D DNA-Binding Protein2
Small Unique Nuclear Receptor Co-Repressor1 2     Nuclear DNA-Binding Protein2
hC1D2 3     Nuclear Nucleic Acid-Binding Protein C1D2
SUNCOR2 5     Small Unique Nuclear Receptor Corepressor2
LRP12     

External Ids:    HGNC: 299111   Entrez Gene: 104382   Ensembl: ENSG000001972237   OMIM: 6069975   UniProtKB: Q139013   

Export aliases for C1D gene to outside databases

Previous GC identifers: GC02M068402 GC02M068227 GC02M068243 GC02M068125 GC02M068006


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for C1D Gene:
The protein encoded by this gene is a DNA binding and apoptosis-inducing protein and is localized in the nucleus.
It is also a Rac3-interacting protein which acts as a corepressor for the thyroid hormone receptor. This protein
is thought to regulate TRAX/Translin complex formation. Alternate splicing results in multiple transcript
variants that encode the same protein. Multiple pseudogenes of this gene are found on chromosome 10.(provided by
RefSeq, Jun 2010)

GeneCards Summary for C1D Gene: 
C1D (C1D nuclear receptor corepressor) is a protein-coding gene. Diseases associated with C1D include botulism, and cerebral amyloid angiopathy, and among its related super-pathways are Deadenylation-dependent mRNA decay. GO annotations related to this gene include ligand-dependent nuclear receptor binding and RNA binding.

UniProtKB/Swiss-Prot: C1D_HUMAN, Q13901
Function: Plays a role in the recruitment of the RNA exosome complex to pre-rRNA to mediate the 3'-5' end
processing of the 5.8S rRNA; this function may include MPHOSPH6. Can activate PRKDC not only in the presence of
linear DNA but also in the presence of supercoiled DNA. Can induce apoptosis in a p53/TP53 dependent manner. May
regulate the TRAX/TSN complex formation. Potentiates transcriptional repression by NR1D1 and THRB (By similarity)

Gene Wiki entry for C1D Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000002.11  NC_018913.2  NT_022184.15  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the C1D gene promoter:
         STAT1   Bach2   STAT1beta   AP-4   POU3F2 (N-Oct-5a)   POU3F2 (N-Oct-5b)   LCR-F1   POU3F2   STAT1alpha   STAT3   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidC1D promoter sequence
   Search SABiosciences Chromatin IP Primers for C1D

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C1D


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2p13-p12   Ensembl cytogenetic band:  2p14   HGNC cytogenetic band: 2p13-p12

C1D Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
C1D gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02M068180:  view genomic region     (about GC identifiers)

Start:
68,268,262 bp from pter      End:
68,338,080 bp from pter
Size:
69,819 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: C1D_HUMAN, Q13901 (See protein sequence)
Recommended Name: Nuclear nucleic acid-binding protein C1D  
Size: 141 amino acids; 16019 Da
Subunit: Monomer and homodimer. Interacts with NR1D1, THRA, THRB, NCOR1 and NCOR2 (By similarity). Interacts with
EXOSC10; the interaction probably mediates the association with the nuclear form of the RNA exosome. The
homodimeric form interacts with TSNAX following gamma-radiation. Interacts with RAC3
Subcellular location: Cytoplasm. Nucleus, nucleolus. Note=EXOSC10 is required for nucleolar localization
Secondary accessions: A8K336 D6W5F8 Q05D64

Explore the universe of human proteins at neXtProt for C1D: NX_Q13901

Explore proteomics data for C1D at MOPED 

Post-translational modifications:

  • UniProtKB: Phosphorylated by PRKDC
  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q13901

  • C1D Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    C1D Protein Expression
    REFSEQ proteins (4 alternative transcripts): 
    NP_001177192.1  NP_001177194.1  NP_006324.1  NP_775269.1  

    ENSEMBL proteins: 
     ENSP00000348107   ENSP00000384304   ENSP00000386468   ENSP00000386779  

    Human Recombinant Protein Products for C1D: 
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    Novus Biologicals C1D Proteins
    Novus Biologicals C1D Lysates
    Sino Biological Recombinant Protein for C1D
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for C1D 

    Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000176nuclear exosome (RNase complex) TAS17412707
    GO:0005634nucleus IDA--
    GO:0005730nucleolus IDA--
    GO:0005739mitochondrion IDA--
    GO:0017053transcriptional repressor complex IEA--

    C1D for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    2 InterPro protein domains:
     IPR011082 Exosome-assoc_fac/DNA_repair
     IPR007146 Sas10/Utp3/C1D

    Graphical View of Domain Structure for InterPro Entry Q13901

    ProtoNet protein and cluster: Q13901

    UniProtKB/Swiss-Prot: C1D_HUMAN, Q13901
    Similarity: Belongs to the C1D family


    C1D for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: C1D_HUMAN, Q13901
    Function: Plays a role in the recruitment of the RNA exosome complex to pre-rRNA to mediate the 3'-5' end
    processing of the 5.8S rRNA; this function may include MPHOSPH6. Can activate PRKDC not only in the presence of
    linear DNA but also in the presence of supercoiled DNA. Can induce apoptosis in a p53/TP53 dependent manner. May
    regulate the TRAX/TSN complex formation. Potentiates transcriptional repression by NR1D1 and THRB (By similarity)
    Induction: By gamma-radiation

         Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding IEA--
    GO:0003714transcription corepressor activity IEA--
    GO:0003723RNA binding IDA17412707
    GO:0005515protein binding IPI17412707
    GO:0016922ligand-dependent nuclear receptor binding IEA--
         
    C1D for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for C1D 
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for C1D 
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    miRNA
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    miRTarBase miRNAs that target C1D:
    hsa-mir-30a (MIRT005157), hsa-mir-192 (MIRT004148)

    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat C1D
    8/10 QIAGEN miScript miRNA Assays for microRNAs that regulate C1D (see all 10):
    hsa-miR-3163 hsa-miR-520d-5p hsa-miR-522 hsa-miR-3133 hsa-miR-548aa hsa-miR-224* hsa-miR-570 hsa-miR-664
    SwitchGear 3'UTR luciferase reporter plasmidC1D 3' UTR sequence
    Inhib. RNA
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C1D


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for C1D About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Deadenylation-dependent mRNA decay
    RNA degradation0.49

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways




    1         Kegg Pathway  (Kegg details for C1D):
        RNA degradation


    C1D for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for C1D

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/26 Interacting proteins for C1D (Q139011, 3 ENSP000003481074) via UniProtKB, MINT, STRING, and/or I2D (see all 26)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    EXOSC10Q017801, 3, ENSP000003661354EBI-3844053,EBI-358236 I2D: score=2 STRING: ENSP00000366135
    TSNAXQ995983, ENSP000003555994I2D: score=4 STRING: ENSP00000355599
    PRKDCP785273, ENSP000003134204I2D: score=3 STRING: ENSP00000313420
    THRBP108283, ENSP000003488274I2D: score=2 STRING: ENSP00000348827
    NCOR1O753763, ENSP000002687124I2D: score=1 STRING: ENSP00000268712
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000460maturation of 5.8S rRNA IMP17412707
    GO:0006351transcription, DNA-dependent IEA--
    GO:0006915apoptotic process IEA--
    GO:0045892negative regulation of transcription, DNA-dependent IEA--

    C1D for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    C1D for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for C1D

    6 Novoseek inferred chemical compound relationships for C1D gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    oligonucleotide 25 1 9081096 (1)
    serine 9.95 3 8206988 (1), 10867876 (1), 8647861 (1)
    proline 9.69 2 2233723 (1), 10867876 (1)
    arginine 5.4 3 9757574 (1), 8647861 (1), 8670298 (1)
    zinc 3.19 1 11076952 (1)
    steroid 0 1 11303722 (1)

    Search CenterWatch for drugs/clinical trials and news about C1D

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for C1D gene (4 alternative transcripts): 
    NM_001190263.1  NM_001190265.1  NM_006333.3  NM_173177.2  

    Unigene Cluster for C1D:

    C1D nuclear receptor corepressor
    Hs.602900  [show with all ESTs]
    Unigene Representative Sequence: NM_001190265
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000355848(uc002sec.3 uc002seb.3) ENST00000407324(uc002sea.4 uc010fdc.3 uc021viu.1)
    ENST00000410067 ENST00000409302 ENST00000479484 ENST00000485709 ENST00000470189

    Congresses - knowledge worth sharing:  
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

    miRNA
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    8/10 QIAGEN miScript miRNA Assays for microRNAs that regulate C1D (see all 10):
    hsa-miR-3163 hsa-miR-520d-5p hsa-miR-522 hsa-miR-3133 hsa-miR-548aa hsa-miR-224* hsa-miR-570 hsa-miR-664
    SwitchGear 3'UTR luciferase reporter plasmidC1D 3' UTR sequence
    Inhib. RNA
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      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C1D

    Additional mRNA sequence: 

    AK290451.1 BC005235.1 BC009584.1 BC009589.1 BC016284.2 X95592.1 

    14 DOTS entries:

    DT.100797251  DT.452941  DT.91770516  DT.121253086  DT.97764095  DT.91770502  DT.121253037  DT.91770509 
    DT.121253092  DT.100797247  DT.121253051  DT.121253132  DT.97858764  DT.95329394 

    24/430 AceView cDNA sequences (see all 430):

    AY183476 CB306200 NM_000945 AW014787 BM263178 BC014022 BQ636280 BU581314 
    BU688593 BX109819 BM354091 AA019009 CR593156 BM786368 AI989469 AI435863 
    AA283054 BU675203 AI866855 W01341 CB160277 AA954730 BU177986 AA279031 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    C1D expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ATGACTGTAC
    C1D Expression
    About this image


    See C1D Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for C1D

    SOURCE GeneReport for Unigene cluster: Hs.602900

    UniProtKB/Swiss-Prot: C1D_HUMAN, Q13901
    Tissue specificity: Ubiquitous. Expressed at very high levels in the hippocampus, medulla oblongata, mammary
    gland, thyroid and salivary gland. Expressed at high levels in the fetal; lung, liver and kidney. Expressed at
    low levels in skeletal muscle, appendix, heart, lung and colon

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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C1D

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for C1D gene from 5/13 species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia C1d1 , 5 C1D nuclear receptor co-repressor1, 5 87.38(n)1
    90.71(a)1
      11 (9.89 cM)5
    573161  NM_020558.31  NP_065583.21 
     172575795 
    chicken
    (Gallus gallus)
    Aves C1D1 C1D nuclear receptor corepressor 77.13(n)
    76.64(a)
      421267  NM_001031036.2  NP_001026207.2 
    lizard
    (Anolis carolinensis)
    Reptilia C1D6
    Uncharacterized protein
    81(a)
    1 ↔ 1
    1(126524250-126530358)
    African clawed frog
    (Xenopus laevis)
    Amphibia 480305082   -- 75.76(n)    48030508 
    zebrafish
    (Danio rerio)
    Actinopterygii wufc33g022 Transcribed sequence with weak similarity to protein more 74.56(n)    BI673950.1 


    ENSEMBL Gene Tree for C1D (if available)
    TreeFam Gene Tree for C1D (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for C1D gene

    C1D for paralogs           About GeneDecksing


    4 Pseudogenes.org Pseudogenes for C1D
    PGOHUM00000238558 PGOHUM00000238559 PGOHUM00000238560 PGOHUM00000242386


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/509 SNPs in C1D are shown (see all 509)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1496328371,2
    --68269094(+) GGACTC/TCTCAT 4 -- ds50010--------
    rs1863983181,2
    --68269359(+) CTTTAC/TTGAGA 4 -- ut310--------
    rs1896839311,2
    --68269456(+) GGACAC/TAGAGG 4 -- ut310--------
    rs1817294501,2
    --68269564(+) GTATCC/TATACA 4 -- ut310--------
    rs1862731591,2
    C--68269609(+) CTTAAC/TATCAT 4 -- ut310--------
    rs2019233831,2
    --68269776(+) GAAAT-/AAGAGTC 4 -- ut310--------
    rs39618031,2
    A--68269843(+) AGTGCA/TAATCA 4 -- ut31 ese30--------
    rs1905985901,2
    --68269847(+) CTAATC/GAATAA 4 -- ut310--------
    rs28617951,2
    A--68269939(+) CCTTGC/TCCTGC 4 -- ut31 ese30--------
    rs29020521,2
    A--68269957(+) TTATTC/TTgcgg 4 -- ut310--------

    HapMap Linkage Disequilibrium report for C1D (68268262 - 68338080 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for C1D:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv525802CNV Loss19592680
    nsv834251CNV Loss17160897

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 606997    OMIM disorders: --

    16 diseases for C1D:    About MalaCards
    botulism    cerebral amyloid angiopathy    primary ciliary dyskinesia    disseminated intravascular coagulation
    vaccinia    polymyositis    scleroderma    thyroiditis
    meningioma    cerebritis    ischemia    rheumatoid arthritis
    arthritis    hepatocellular carcinoma    breast cancer    leukemia

    1 disease from the University of Copenhagen DISEASES database for C1D:
    Primary ciliary dyskinesia

    C1D for disorders           About GeneDecksing

    1 Novoseek inferred disease relationship for C1D gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    inflammation 6.82 1 19887013 (1)

    Genetic Association Database (GAD): C1D
    Human Genome Epidemiology (HuGE) Navigator: C1D (4 documents)

    Export disorders for C1D gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for C1D gene, integrated from 9 sources (see all 94):
    (articles sorted by number of sources associating them with C1D)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. C1D and hMtr4p associate with the human exosome subunit PM/Scl-100 and are involved in pre-rRNA processing. (PubMed id 17412707)1, 2, 3 Schilders G.... Pruijn G.J.M. (2007)
    2. DNA damage-dependent interaction of the nuclear matrix protein C1D with Translin-associated factor X (TRAX). (PubMed id 11801738)1, 2, 3 Erdemir T.... Yavuzer U. (2002)
    3. cDNA cloning, recombinant expression and characterization of polypetides with exceptional DNA affinity. (PubMed id 9469821)1, 2, 3 Nehls P.... Werner D. (1998)
    4. Risk of meningioma and common variation in genes rela ted to innate immunity. (PubMed id 20406964)1, 4 Rajaraman P....Inskip P.D. (2010)
    5. Polymorphisms in innate immunity genes and risk of ch ildhood leukemia. (PubMed id 20438785)1, 4 Han S....Kang D. (2010)
    6. C1D is a major autoantibody target in patients with the polymyositis-scleroderma overlap syndrome. (PubMed id 17599775)1, 3 Schilders G....Pruijn G.J. (2007)
    7. Induction of apoptosis by overexpression of the DNA-binding and DNA- PK-activating protein C1D. (PubMed id 10362552)1, 2 Rothbarth K....Werner D. (1999)
    8. DNA end-independent activation of DNA-PK mediated via association with the DNA-binding protein C1D. (PubMed id 9679063)1, 2 Yavuzer U....Jackson S.P. (1998)
    9. Identification of a novel Rac3-interacting protein C1D. (PubMed id 9852280)1, 2 Haataja L.... Heisterkamp N. (1998)
    10. Cloning and characterization of a corepressor and potential component of the nuclear hormone receptor repression complex. (PubMed id 9405624)1, 3 Zamir I....Lazar M.A. (1997)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 10438 HGNC: 29911 AceView: PPP3R1andC1DandLOC116143 Ensembl:ENSG00000197223 euGenes: HUgn10438
    ECgene: C1D Kegg: 10438 H-InvDB: C1D

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for C1D Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for C1D gene:
    Search GeneIP for patents involving C1D

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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