Aliases for C19orf84 Gene
External Ids for C19orf84 Gene
- HGNC: 27112
- Entrez Gene: 147646
- Ensembl: ENSG00000262874
- UniProtKB: I3L1E1
Previous GeneCards Identifiers for C19orf84 Gene
- GC19M051892
Summaries for C19orf84 Gene
GeneCards Summary for C19orf84 Gene
C19orf84 (Chromosome 19 Open Reading Frame 84) is a Protein Coding gene.
No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C19orf84 Gene
Genomics for C19orf84 Gene
Regulatory Elements for C19orf84 Gene
Enhancers for C19orf84 Gene
| GeneHancer Identifier | Enhancer Score | Enhancer Sources | Gene-Enhancer Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Gene Targets for Enhancer |
|---|---|---|---|---|---|---|---|---|
| GH19G051393 | 1.5 | FANTOM5 ENCODE | 20.5 | -4.5 | -4474 | 2.8 | HDGF PKNOX1 CREB3L1 ARNT WRNIP1 ZFP64 ARID4B SIN3A YY1 ZNF143 | ZNF766 ZNF577 SPACA6P-AS ZNF836 C19orf84 ZNF432 ZNF616 ZNF880 ENSG00000268015 ZNF175 |
| GH19G051388 | 1.2 | Ensembl ENCODE | 21 | +0.4 | 352 | 3.2 | HDGF ATF1 CREB3L1 ARNT ARID4B DMAP1 ZNF48 ZNF263 JUNB ZNF592 | C19orf84 LIM2 |
| GH19G051386 | 1.1 | Ensembl ENCODE | 15.1 | +3.0 | 2977 | 1.4 | LEF1 FOXA2 CBX3 SAP130 RAD21 RARA ZNF507 TEAD3 POLR2A EGR1 | C19orf84 LIM2 NKG7 |
| GH19G051847 | 0.3 | FANTOM5 | 22.2 | -457.3 | -457269 | 0.5 | CLDND2 ZNF610 C19orf84 ENSG00000269483 ZNF616 SIGLEC14 LOC105369197 VN1R98P | |
| GH19G051392 | 0.4 | FANTOM5 | 7.3 | -2.3 | -2334 | 0.2 | ZNF592 | C19orf84 SIGLEC14 LOC105372446 |
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around C19orf84 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Location for C19orf84 Gene
- Chromosome:
- 19
- Start:
- 51,388,289 bp from pter
- End:
- 51,390,574 bp from pter
- Size:
- 2,286 bases
- Orientation:
- Minus strand
Genomic View for C19orf84 Gene
Genes around C19orf84 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 19q13.41 by Ensembl
- 19q13.41 by Entrez Gene
- 19q13.41 by HGNC
C19orf84 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for C19orf84 Gene
Proteins for C19orf84 Gene
-
Protein details for C19orf84 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- I3L1E1-CS084_HUMAN
- Recommended name:
- Uncharacterized protein C19orf84
- Protein Accession:
- I3L1E1
Protein attributes for C19orf84 Gene
- Size:
- 186 amino acids
- Molecular mass:
- 19614 Da
- Quaternary structure:
- No Data Available
Protein Expression for C19orf84 Gene
Post-translational modifications for C19orf84 Gene
No Post-translational modifications
Other Protein References for C19orf84 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for C19orf84
-
Abcam antibodies for C19orf84
- Invitrogen Antibodies for C19orf84
- Search GeneTex for Antibodies for C19orf84
Protein Products
-
OriGene Purified Proteins for C19orf84
- Search Origene for MassSpec and Protein Over-expression Lysates for C19orf84
- Origene Custom Protein Services for C19orf84
- Novus Biologicals proteins for C19orf84
- Search GeneTex for Proteins for C19orf84
Assay Products
No data available for DME Specific Peptides for C19orf84 Gene
Domains & Families for C19orf84 Gene
Protein Domains for C19orf84 Gene
- ProtoNet:
Graphical View of Domain Structure for InterPro Entry
No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C19orf84 Gene
Function for C19orf84 Gene
Phenotypes for C19orf84 Gene
- GenomeRNAi human phenotypes for C19orf84:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for C19orf84
-
- Search ViGene Biosciences for C19orf84
CRISPR Products
-
OriGene CRISPR knockouts for C19orf84
miRNA Products
- Search ViGene Biosciences for C19orf84
Inhibitory RNA Products
- Search ViGene Biosciences for C19orf84
Clone Products
-
OriGene ORF clones in human for C19orf84
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- VectorBuilder custom plasmid, inducible vectors for C19orf84
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for C19orf84
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for C19orf84 Gene
Localization for C19orf84 Gene
No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for C19orf84 Gene
Transcripts for C19orf84 Gene
mRNA/cDNA for C19orf84 Gene
- (1) REFSEQ mRNAs :
- (5) Selected AceView cDNA sequences:
- (2) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
-
OriGene CRISPR knockouts for C19orf84
miRNA Products
- Search ViGene Biosciences for C19orf84
Inhibitory RNA Products
- Search ViGene Biosciences for C19orf84
Clone Products
-
OriGene ORF clones in human for C19orf84
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- VectorBuilder custom plasmid, inducible vectors for C19orf84
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for C19orf84
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
Expression for C19orf84 Gene
mRNA differential expression in normal tissues according to GTEx for C19orf84 Gene
This gene is overexpressed in Testis (x42.9).
This gene is overexpressed in Placenta (42.9), Esophagus (18.7), and Lung (7.3).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C19orf84 Gene
NURSA nuclear receptor signaling pathways regulating expression of C19orf84 Gene:
C19orf84Primer Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for C19orf84 Gene
Orthologs for C19orf84 Gene
This gene was present in the common ancestor of mammals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | LOC748798 34 |
|
||
| cow (Bos Taurus) |
Mammalia | LOC100848300 34 |
|
||
| mouse (Mus musculus) |
Mammalia | Lim2 35 35 |
|
OneToMany |
- Species where no ortholog for C19orf84 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- dog (Canis familiaris)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- lizard (Anolis carolinensis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- oppossum (Monodelphis domestica)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rainbow trout (Oncorhynchus mykiss)
- rat (Rattus norvegicus)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
- zebrafish (Danio rerio)
Paralogs for C19orf84 Gene
No data available for Paralogs for C19orf84 Gene
Variants for C19orf84 Gene
| SNP ID | Clin | Chr 19 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs113926789 | Uncertain significance | 51,387,939(+) | TGCCC(A/G)AGCCC | intron-variant, utr-variant-5-prime | |
| rs539594698 | Uncertain significance | 51,387,953(+) | TTCTG(C/T)CACGG | intron-variant, utr-variant-5-prime | |
| rs568064524 | Uncertain significance | 51,387,905(+) | TCTCA(C/T)GCCTG | intron-variant | |
| rs886054601 | Uncertain significance | 51,387,941(-) | GAGGG(C/G)TCGGG | intron-variant, downstream-variant-500B, utr-variant-5-prime | |
| rs1000110447 | -- | 51,389,792(+) | TATTC(C/T)GAACC | intron-variant, upstream-variant-2KB |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv21876 | CNV | loss | 19812545 |
| nsv1140251 | OTHER | inversion | 24896259 |
Gene Damage Index Score:
9.37;
88.43% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for C19orf84 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- C19orf84
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C19orf84 Gene
Disorders for C19orf84 Gene
Relevant External Links for C19orf84
- Atlas of Genetics and Cytogenetics in Oncology and Haematology:
- C19orf84
No disorders were found for C19orf84 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C19orf84 Gene
Publications for C19orf84 Gene
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3 64
- The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J. … Lucas S.M. (Nature 2004) 4 64
Products for C19orf84 Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Browse OriGene Antibodies
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for C19orf84
- Search Origene for MassSpec and Protein Over-expression Lysates for C19orf84
- Origene Custom Protein Services for C19orf84
- Browse OriGene Inhibitory RNA Products For C19orf84
- Browse OriGene qPCR primer pairs and template standards
- OriGene CRISPR knockouts for C19orf84
- OriGene ORF clones in human for C19orf84
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For C19orf84
- GenScript: Next-day shipping cDNA ORF clone for C19orf84 in any vector
- GenScript Custom Purified and Recombinant Proteins Services for C19orf84
- GenScript Custom Assay Services for C19orf84
- GenScript Custom overexpressing Cell Line Services for C19orf84
- Browse GenScript CRISPR for C19orf84
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for C19orf84
- Browse Sino Biological cDNA Clones
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Proteins
- Sino Biological Antibodies
- Sino Biological ELISA Kits and Pair Sets
- Sino Biological Cell Lysates
- Sino Biological qPCR Primers
- Sino Biological CRO Services for Proteins, Antibodies and Genes
- Sino Biological Transfection Reagents
- Novus Biologicals Antibodies for C19orf84
- Novus Biologicals proteins for C19orf84
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Invitrogen Antibodies for C19orf84
- Cyagen custom Knockout/knockin (KOKI) mouse models for C19orf84
- VectorBuilder custom plasmid, inducible vectors for C19orf84
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for C19orf84
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for C19orf84 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer