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Aliases for C19orf84 Gene

Aliases for C19orf84 Gene

  • Chromosome 19 Open Reading Frame 84 2 3 5

External Ids for C19orf84 Gene

Previous GeneCards Identifiers for C19orf84 Gene

  • GC19M051892

Summaries for C19orf84 Gene

GeneCards Summary for C19orf84 Gene

C19orf84 (Chromosome 19 Open Reading Frame 84) is a Protein Coding gene.

Additional gene information for C19orf84 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C19orf84 Gene

Genomics for C19orf84 Gene

GeneHancer (GH) Regulatory Elements for C19orf84 Gene

Promoters and enhancers for C19orf84 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH19I051388 Promoter/Enhancer 1.6 EPDnew Ensembl ENCODE 571 +0.4 352 3.2 HDGF ATF1 ARNT ARID4B DMAP1 ZNF48 NCOA2 POLR2B E2F8 ATF7 C19orf84 LIM2
GH19I051393 Promoter/Enhancer 1.9 FANTOM5 Ensembl ENCODE 20.6 -4.5 -4473 2.8 HDGF PKNOX1 SMAD1 ARNT ZFP64 ARID4B SIN3A IRF4 YY1 POLR2B ENSG00000268889 LOC105372446 ZNF841 ZNF766 ZNF577 ZNF616 ZNF175 ZNF836 ZNF432 ZNF614
GH19I051386 Promoter/Enhancer 1.4 EPDnew Ensembl ENCODE 15.2 +3.0 2976 1.4 FOXA2 SAP130 RAD21 RARA TEAD3 SCRT2 NR2F6 GATAD2A SOX5 RFX1 LIM2 C19orf84 NKG7
GH19I051847 Enhancer 0.2 FANTOM5 22.2 -457.3 -457269 0.5 LOC105369197 CLDND2 ZNF610 C19orf84 ENSG00000269483 ZNF616 SIGLEC14 VN1R98P ZNF577
GH19I051392 Enhancer 0.3 FANTOM5 7.3 -2.3 -2333 0.2 ZNF592 ENSG00000268889 LOC105372446 C19orf84 SIGLEC14
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around C19orf84 on UCSC Golden Path with GeneCards custom track

Genomic Locations for C19orf84 Gene

Genomic Locations for C19orf84 Gene
chr19:51,388,289-51,390,574
(GRCh38/hg38)
Size:
2,286 bases
Orientation:
Minus strand
chr19:51,891,543-51,893,828
(GRCh37/hg19)

Genomic View for C19orf84 Gene

Genes around C19orf84 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C19orf84 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C19orf84 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C19orf84 Gene

Proteins for C19orf84 Gene

  • Protein details for C19orf84 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    I3L1E1-CS084_HUMAN
    Recommended name:
    Uncharacterized protein C19orf84
    Protein Accession:
    I3L1E1

    Protein attributes for C19orf84 Gene

    Size:
    186 amino acids
    Molecular mass:
    19614 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C19orf84 Gene

Post-translational modifications for C19orf84 Gene

No Post-translational modifications

Other Protein References for C19orf84 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C19orf84 Gene

Domains & Families for C19orf84 Gene

Gene Families for C19orf84 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for C19orf84 Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C19orf84: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C19orf84 Gene

Function for C19orf84 Gene

Phenotypes for C19orf84 Gene

GenomeRNAi human phenotypes for C19orf84:
genes like me logo Genes that share phenotypes with C19orf84: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for C19orf84 Gene

Localization for C19orf84 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for C19orf84 Gene

Pathways & Interactions for C19orf84 Gene

SuperPathways for C19orf84 Gene

No Data Available

Interacting Proteins for C19orf84 Gene

Gene Ontology (GO) - Biological Process for C19orf84 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C19orf84 Gene

Drugs & Compounds for C19orf84 Gene

No Compound Related Data Available

Transcripts for C19orf84 Gene

mRNA/cDNA for C19orf84 Gene

(1) REFSEQ mRNAs :
(5) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for C19orf84 Gene

No ASD Table

Relevant External Links for C19orf84 Gene

GeneLoc Exon Structure for
C19orf84
ECgene alternative splicing isoforms for
C19orf84

Expression for C19orf84 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for C19orf84 Gene

mRNA differential expression in normal tissues according to GTEx for C19orf84 Gene

This gene is overexpressed in Testis (x42.9).

Protein differential expression in normal tissues from HIPED for C19orf84 Gene

This gene is overexpressed in Placenta (42.9), Esophagus (18.7), and Lung (7.3).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C19orf84 Gene



Protein tissue co-expression partners for C19orf84 Gene

NURSA nuclear receptor signaling pathways regulating expression of C19orf84 Gene:

C19orf84
genes like me logo Genes that share expression patterns with C19orf84: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for C19orf84 Gene

Orthologs for C19orf84 Gene

This gene was present in the common ancestor of mammals.

Orthologs for C19orf84 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC748798 33
  • 98.92 (n)
cow
(Bos Taurus)
Mammalia LOC100848300 33
  • 73.7 (n)
mouse
(Mus musculus)
Mammalia Lim2 34 34
  • 61 (a)
OneToMany
Species where no ortholog for C19orf84 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C19orf84 Gene

ENSEMBL:
Gene Tree for C19orf84 (if available)
TreeFam:
Gene Tree for C19orf84 (if available)

Paralogs for C19orf84 Gene

No data available for Paralogs for C19orf84 Gene

Variants for C19orf84 Gene

Sequence variations from dbSNP and Humsavar for C19orf84 Gene

SNP ID Clin Chr 19 pos Variation AA Info Type
rs113926789 uncertain-significance, Cortical pulverulent cataract 51,387,939(-) G/A/T downstream_transcript_variant
rs539594698 uncertain-significance, Cortical pulverulent cataract 51,387,953(-) C/T downstream_transcript_variant
rs568064524 uncertain-significance, Cortical pulverulent cataract 51,387,905(-) C/T downstream_transcript_variant
rs891719203 uncertain-significance, Cortical pulverulent cataract 51,387,941(-) G/C downstream_transcript_variant
rs1000110447 -- 51,389,792(-) C/T intron_variant

Structural Variations from Database of Genomic Variants (DGV) for C19orf84 Gene

Variant ID Type Subtype PubMed ID
esv21876 CNV loss 19812545
nsv1140251 OTHER inversion 24896259

Variation tolerance for C19orf84 Gene

Gene Damage Index Score: 9.37; 88.43% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for C19orf84 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
C19orf84

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C19orf84 Gene

Disorders for C19orf84 Gene

Additional Disease Information for C19orf84

No disorders were found for C19orf84 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C19orf84 Gene

Publications for C19orf84 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 2 3 58
  2. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J … Lucas SM (Nature 2004) 4 58

Products for C19orf84 Gene

Sources for C19orf84 Gene

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