Aliases for C19orf73 Gene
External Ids for C19orf73 Gene
- HGNC: 25534
- Entrez Gene: 55150
- Ensembl: ENSG00000221916
- UniProtKB: Q9NVV2
Previous GeneCards Identifiers for C19orf73 Gene
- GC19M054315
- GC19M049621
- GC19M045997
Summaries for C19orf73 Gene
GeneCards Summary for C19orf73 Gene
C19orf73 (Chromosome 19 Open Reading Frame 73) is a Protein Coding gene.
No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C19orf73 Gene
Genomics for C19orf73 Gene
Regulatory Elements for C19orf73 Gene
Enhancers for C19orf73 Gene
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around C19orf73 on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the C19orf73 gene promoter:
Regulatory Element Products
Genomic Location for C19orf73 Gene
- Chromosome:
- 19
- Start:
- 49,118,397 bp from pter
- End:
- 49,119,140 bp from pter
- Size:
- 744 bases
- Orientation:
- Minus strand
Genomic View for C19orf73 Gene
Genes around C19orf73 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 19q13.33 by Ensembl
- 19q13.33 by Entrez Gene
- 19q13.33 by HGNC
C19orf73 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for C19orf73 Gene
Proteins for C19orf73 Gene
-
Protein details for C19orf73 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9NVV2-CS073_HUMAN
- Recommended name:
- Putative uncharacterized protein C19orf73
- Protein Accession:
- Q9NVV2
- Q6NSX4
Protein attributes for C19orf73 Gene
- Size:
- 129 amino acids
- Molecular mass:
- 13750 Da
- Quaternary structure:
- No Data Available
Post-translational modifications for C19orf73 Gene
No Post-translational modifications
Other Protein References for C19orf73 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for C19orf73
- Novus Biologicals Antibodies for C19orf73
-
Abcam antibodies for C19orf73
- Invitrogen Antibodies for C19orf73
- Search GeneTex for Antibodies for C19orf73
Protein Products
-
OriGene Purified Proteins for C19orf73
- Search Origene for MassSpec and Protein Over-expression Lysates for C19orf73
- Origene Custom Protein Services for C19orf73
- Search GeneTex for Proteins for C19orf73
Assay Products
No data available for DME Specific Peptides for C19orf73 Gene
Domains & Families for C19orf73 Gene
Protein Domains for C19orf73 Gene
- ProtoNet:
Graphical View of Domain Structure for InterPro Entry
No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C19orf73 Gene
Function for C19orf73 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | 25416956 |
Phenotypes for C19orf73 Gene
- GenomeRNAi human phenotypes for C19orf73:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for C19orf73
-
-
ViGene Biosciences lentiviral particle packaged cDNA for C19orf73 gene
- Search ViGene Biosciences for C19orf73
CRISPR Products
-
OriGene CRISPR knockouts for C19orf73
-
Santa Cruz Biotechnology (SCBT) CRISPR for C19orf73
- GenScript: Design CRISPR guide RNA sequences for C19orf73
miRNA for C19orf73 Gene
- miRTarBase miRNAs that target C19orf73
miRNA Products
- Search ViGene Biosciences for C19orf73
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for C19orf73
- Browse OriGene Inhibitory RNA Products For C19orf73
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Clone Products
-
OriGene ORF clones in human for C19orf73
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for C19orf73
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for C19orf73
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for C19orf73
-
ViGene Biosciences adenoviral particle packaged cDNA for C19orf73 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for C19orf73 gene
- Search ViGene Biosciences for C19orf73
Flow Cytometry Products
No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C19orf73 Gene
Localization for C19orf73 Gene
| Compartment | Confidence |
|---|---|
| extracellular | 2 |
| mitochondrion | 2 |
| nucleus | 2 |
| cytosol | 1 |
No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C19orf73 Gene
Transcripts for C19orf73 Gene
mRNA/cDNA for C19orf73 Gene
- (1) REFSEQ mRNAs :
- (6) Additional mRNA sequences :
- (32) Selected AceView cDNA sequences:
- (1) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for C19orf73 Gene
CRISPR Products
-
OriGene CRISPR knockouts for C19orf73
-
Santa Cruz Biotechnology (SCBT) CRISPR for C19orf73
- GenScript: Design CRISPR guide RNA sequences for C19orf73
miRNA Products
- Search ViGene Biosciences for C19orf73
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for C19orf73
- Browse OriGene Inhibitory RNA Products For C19orf73
- Search ViGene Biosciences for C19orf73
Clone Products
-
OriGene ORF clones in human for C19orf73
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for C19orf73
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for C19orf73
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
Expression for C19orf73 Gene
NURSA nuclear receptor signaling pathways regulating expression of C19orf73 Gene:
C19orf73SOURCE GeneReport for Unigene cluster for C19orf73 Gene:
Hs.458310Primer Products
-
OriGene qPCR primer pairs for C19orf73
-
OriGene qPCR primer pairs and template standards for C19orf73
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for C19orf73 Gene
Orthologs for C19orf73 Gene
This gene was present in the common ancestor of human and chimp.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | C19H19orf73 34 |
|
||
| C19orf73 35 |
|
OneToOne |
- Species where no ortholog for C19orf73 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- cow (Bos Taurus)
- dog (Canis familiaris)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- lizard (Anolis carolinensis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- mouse (Mus musculus)
- oppossum (Monodelphis domestica)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rainbow trout (Oncorhynchus mykiss)
- rat (Rattus norvegicus)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
- zebrafish (Danio rerio)
Paralogs for C19orf73 Gene
No data available for Paralogs for C19orf73 Gene
Variants for C19orf73 Gene
| SNP ID | Clin | Chr 19 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000029134 | -- | 49,118,920(+) | GGGTG(C/G)AGAAT | intron-variant, downstream-variant-500B, upstream-variant-2KB, reference, missense | |
| rs1001607866 | -- | 49,120,048(+) | CGCGG(C/T)GGTGC | intron-variant, upstream-variant-2KB | |
| rs1001989135 | -- | 49,119,243(+) | CGACC(C/T)CTCCC | upstream-variant-2KB | |
| rs1003027372 | -- | 49,121,037(+) | CTTCA(C/T)ATCTC | intron-variant, upstream-variant-2KB | |
| rs1003604852 | -- | 49,118,035(+) | GGTCA(A/C)CACAC | intron-variant, nc-transcript-variant, downstream-variant-500B, upstream-variant-2KB, utr-variant-3-prime |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv3619n100 | CNV | gain | 25217958 |
| dgv3620n100 | CNV | gain | 25217958 |
| dgv3621n100 | CNV | gain | 25217958 |
| esv2760526 | CNV | gain | 21179565 |
| nsv1060108 | CNV | gain | 25217958 |
| nsv819445 | CNV | gain | 19587683 |
| nsv833857 | CNV | loss | 17160897 |
| nsv833859 | CNV | loss | 17160897 |
| nsv9739 | CNV | gain+loss | 18304495 |
Residual Variation Intolerance Score:
76.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
1.44;
28.27% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for C19orf73 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- C19orf73
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C19orf73 Gene
Disorders for C19orf73 Gene
Relevant External Links for C19orf73
- Atlas of Genetics and Cytogenetics in Oncology and Haematology:
- C19orf73
No disorders were found for C19orf73 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C19orf73 Gene
Publications for C19orf73 Gene
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3 64
- A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3 64
- hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P. … Vidal M. (Genomics 2007) 3 64
- The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J. … Lucas S.M. (Nature 2004) 4 64
Products for C19orf73 Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
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- Browse Cell Culture Products
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- Browse Proteome Profiler Antibody Arrays
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- Custom Antibody ServicesOriGene Antibodies for C19orf73
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for C19orf73
- Search Origene for MassSpec and Protein Over-expression Lysates for C19orf73
- Origene Custom Protein Services for C19orf73
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for C19orf73
- Browse OriGene Inhibitory RNA Products For C19orf73
- OriGene qPCR primer pairs and template standards for C19orf73
- OriGene qPCR primer pairs for C19orf73
- OriGene CRISPR knockouts for C19orf73
- OriGene ORF clones in human for C19orf73
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For C19orf73
- GenScript: Next-day shipping cDNA ORF clone for C19orf73 in any vector
- GenScript Custom Purified and Recombinant Proteins Services for C19orf73
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- GenScript: Design CRISPR guide RNA sequences for C19orf73
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- Novus Biologicals Antibodies for C19orf73
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- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- ViGene Biosciences adenoviral particle packaged cDNA for C19orf73 gene
- ViGene Biosciences lentiviral particle packaged cDNA for C19orf73 gene
- Search ViGene Biosciences for C19orf73
- Horizon Cell Lines for C19orf73
- Cyagen custom Knockout/knockin (KOKI) mouse models for C19orf73
- VectorBuilder custom plasmid, inducible vectors for C19orf73
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for C19orf73
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for C19orf73 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer