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Aliases for C19orf68 Gene

Aliases for C19orf68 Gene

  • Chromosome 19 Open Reading Frame 68 2 3 5

External Ids for C19orf68 Gene

Previous GeneCards Identifiers for C19orf68 Gene

  • GC19P053366
  • GC19P048673
  • GC19P045057

Summaries for C19orf68 Gene

GeneCards Summary for C19orf68 Gene

C19orf68 (Chromosome 19 Open Reading Frame 68) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C19orf68 Gene

Genomics for C19orf68 Gene

Regulatory Elements for C19orf68 Gene

Promoters for C19orf68 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around C19orf68 on UCSC Golden Path with GeneCards custom track

Genomic Location for C19orf68 Gene

48,170,662 bp from pter
48,197,621 bp from pter
26,960 bases
Plus strand

Genomic View for C19orf68 Gene

Genes around C19orf68 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C19orf68 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C19orf68 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C19orf68 Gene

Proteins for C19orf68 Gene

  • Protein details for C19orf68 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized protein C19orf68
    Protein Accession:

    Protein attributes for C19orf68 Gene

    627 amino acids
    Molecular mass:
    70073 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAH43386.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for C19orf68 Gene

Proteomics data for C19orf68 Gene at MOPED

Post-translational modifications for C19orf68 Gene

  • Ubiquitination at Lys 286
  • Modification sites at PhosphoSitePlus

Other Protein References for C19orf68 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C19orf68 Gene

Domains & Families for C19orf68 Gene

Protein Domains for C19orf68 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C19orf68: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C19orf68 Gene

Function for C19orf68 Gene

Gene Ontology (GO) - Molecular Function for C19orf68 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 20195357
genes like me logo Genes that share ontologies with C19orf68: view
genes like me logo Genes that share phenotypes with C19orf68: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C19orf68 Gene

Localization for C19orf68 Gene

Subcellular locations from

Jensen Localization Image for C19orf68 Gene COMPARTMENTS Subcellular localization image for C19orf68 gene
Compartment Confidence
nucleus 4
cytosol 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C19orf68 Gene

Pathways & Interactions for C19orf68 Gene

SuperPathways for C19orf68 Gene

No Data Available

Interacting Proteins for C19orf68 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
Selected Interacting proteins: Q86XI8-CS068_HUMAN ENSP00000331363 for C19orf68 Gene via UniProtKB I2D STRING

Gene Ontology (GO) - Biological Process for C19orf68 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006915 apoptotic process IBA --
GO:0007275 multicellular organism development IEA --
GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process IBA --
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process IBA --
genes like me logo Genes that share ontologies with C19orf68: view

No data available for Pathways by source and SIGNOR curated interactions for C19orf68 Gene

Drugs & Compounds for C19orf68 Gene

No Compound Related Data Available

Transcripts for C19orf68 Gene

mRNA/cDNA for C19orf68 Gene

Unigene Clusters for C19orf68 Gene

Chromosome 19 open reading frame 68:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for C19orf68 Gene

No ASD Table

Relevant External Links for C19orf68 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C19orf68 Gene

mRNA expression in normal human tissues for C19orf68 Gene

Protein differential expression in normal tissues from HIPED for C19orf68 Gene

This gene is overexpressed in Testis (23.0), Liver, secretome (22.0), and Peripheral blood mononuclear cells (21.2).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C19orf68 Gene

SOURCE GeneReport for Unigene cluster for C19orf68 Gene Hs.664054

genes like me logo Genes that share expression patterns with C19orf68: view

Protein tissue co-expression partners for C19orf68 Gene

- Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for C19orf68 Gene

Orthologs for C19orf68 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C19orf68 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia C18H19orf68 35
  • 86.4 (n)
  • 86.65 (a)
C19orf68 36
  • 89 (a)
(Canis familiaris)
Mammalia C1H19orf68 35
  • 86.9 (n)
  • 85.95 (a)
C19orf68 36
  • 59 (a)
(Mus musculus)
Mammalia 6330408A02Rik 35
  • 76.95 (n)
  • 73.62 (a)
6330408A02Rik 16
6330408A02Rik 36
  • 50 (a)
(Pan troglodytes)
Mammalia C19H19orf68 35
  • 97.96 (n)
  • 98.1 (a)
C19orf68 36
  • 86 (a)
(Rattus norvegicus)
Mammalia RGD1310257 35
  • 76 (n)
  • 73.07 (a)
(Monodelphis domestica)
Mammalia C19orf68 36
  • 48 (a)
(Ornithorhynchus anatinus)
Mammalia C19orf68 36
  • 39 (a)
(Anolis carolinensis)
Reptilia C19orf68 36
  • 34 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia 6330408a02rik 35
  • 50.07 (n)
  • 42.58 (a)
Species with no ortholog for C19orf68:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C19orf68 Gene

Gene Tree for C19orf68 (if available)
Gene Tree for C19orf68 (if available)

Paralogs for C19orf68 Gene

No data available for Paralogs for C19orf68 Gene

Variants for C19orf68 Gene

Sequence variations from dbSNP and Humsavar for C19orf68 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs448222 -- 48,178,810(-) GATCA(C/T)GAGGT intron-variant, upstream-variant-2KB
rs274867 -- 48,172,998(-) TCTCC(C/T)AGTCT intron-variant
rs274868 -- 48,174,463(-) GCAGC(A/G)CAATG intron-variant
rs274869 -- 48,174,891(-) AGTCT(C/T)GGATT intron-variant
rs274870 -- 48,175,757(-) ACTTC(A/G)AGAGA intron-variant

Variation tolerance for C19orf68 Gene

Gene Damage Index Score: 0.82; 17.21% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C19orf68 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for C19orf68 Gene

Disorders for C19orf68 Gene

Relevant External Links for C19orf68

Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for C19orf68 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C19orf68 Gene

Publications for C19orf68 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3 67
  2. A comprehensive resource of interacting protein regions for refining human transcription factor networks. (PMID: 20195357) Miyamoto-Sato E. … Yanagawa H. (PLoS ONE 2010) 3
  3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3
  4. Association between genetic variants in VEGF, ERCC3 and occupational benzene haematotoxicity. (PMID: 19773279) Hosgood H.D. … Lan Q. (Occup Environ Med 2009) 3

Products for C19orf68 Gene

Sources for C19orf68 Gene

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