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Aliases for C19orf68 Gene

Aliases for C19orf68 Gene

  • Chromosome 19 Open Reading Frame 68 2 3

External Ids for C19orf68 Gene

Summaries for C19orf68 Gene

GeneCards Summary for C19orf68 Gene

C19orf68 (Chromosome 19 Open Reading Frame 68) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C19orf68 Gene

Genomics for C19orf68 Gene

Genomic Location for C19orf68 Gene

Start:
48,170,678 bp from pter
End:
48,197,622 bp from pter
Size:
26,945 bases
Orientation:
Plus strand

Genomic View for C19orf68 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for C19orf68 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C19orf68 Gene

Regulatory Elements for C19orf68 Gene

Proteins for C19orf68 Gene

  • Protein details for C19orf68 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q86XI8-CS068_HUMAN
    Recommended name:
    Uncharacterized protein C19orf68
    Protein Accession:
    Q86XI8
    Secondary Accessions:

    Protein attributes for C19orf68 Gene

    Size:
    627 amino acids
    Molecular mass:
    70073 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAH43386.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for C19orf68 Gene

Proteomics data for C19orf68 Gene at MOPED

Post-translational modifications for C19orf68 Gene

  • Modification sites at PhosphoSitePlus
  • Ubiquitination at Lys286

Other Protein References for C19orf68 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C19orf68 Gene

Domains for C19orf68 Gene

Protein Domains for C19orf68 Gene

InterPro:
ProtoNet:
genes like me logo Genes that share domains with C19orf68: view

No data available for Gene Families and UniProtKB/Swiss-Prot for C19orf68 Gene

Function for C19orf68 Gene

Gene Ontology (GO) - Molecular Function for C19orf68 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 20195357
GO:0008270 zinc ion binding --
genes like me logo Genes that share ontologies with C19orf68: view

Phenotypes for C19orf68 Gene

GenomeRNAi human phenotypes for C19orf68:
genes like me logo Genes that share phenotypes with C19orf68: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for C19orf68 Gene

Localization for C19orf68 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for C19orf68 Gene COMPARTMENTS Subcellular localization image for C19orf68 gene
Compartment Confidence
cytosol 2
nucleus 2

Gene Ontology (GO) - Cellular Components for C19orf68 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with C19orf68: view

Pathways for C19orf68 Gene

SuperPathways for C19orf68 Gene

No Data Available

Interacting Proteins for C19orf68 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000331363%0d%0a9606.ENSP00000344818%0d%0a
Selected Interacting proteins: ENSP00000331363 Q86XI8-CS068_HUMAN for C19orf68 Gene via STRING UniProtKB I2D

Gene Ontology (GO) - Biological Process for C19orf68 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0002244 hematopoietic progenitor cell differentiation --
GO:0006511 ubiquitin-dependent protein catabolic process IEA --
GO:0007275 multicellular organismal development IEA --
genes like me logo Genes that share ontologies with C19orf68: view

No data available for Pathways by source for C19orf68 Gene

Transcripts for C19orf68 Gene

mRNA/cDNA for C19orf68 Gene

Unigene Clusters for C19orf68 Gene

Chromosome 19 open reading frame 68:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for C19orf68 Gene

No ASD Table

Relevant External Links for C19orf68 Gene

GeneLoc Exon Structure for
C19orf68
ECgene alternative splicing isoforms for
C19orf68

Expression for C19orf68 Gene

mRNA expression in normal human tissues for C19orf68 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for C19orf68 Gene

SOURCE GeneReport for Unigene cluster for C19orf68 Gene Hs.664054

genes like me logo Genes that share expressions with C19orf68: view

Orthologs for C19orf68 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C19orf68 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C19H19orf68 36
  • 97.96 (n)
  • 98.1 (a)
C19orf68 37
  • 86 (a)
OneToOne
cow
(Bos Taurus)
Mammalia C18H19orf68 36
  • 86.4 (n)
  • 86.65 (a)
C19orf68 37
  • 89 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C19orf68 37
  • 59 (a)
OneToOne
C1H19orf68 36
  • 86.9 (n)
  • 85.95 (a)
mouse
(Mus musculus)
Mammalia 6330408A02Rik 36
  • 76.95 (n)
  • 73.62 (a)
6330408A02Rik 16
6330408A02Rik 37
  • 50 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia C19orf68 37
  • 48 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia C19orf68 37
  • 39 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia RGD1310257 36
  • 76 (n)
  • 73.07 (a)
lizard
(Anolis carolinensis)
Reptilia C19orf68 37
  • 34 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia 6330408a02rik 36
  • 50.07 (n)
  • 42.58 (a)
Species with no ortholog for C19orf68:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C19orf68 Gene

ENSEMBL:
Gene Tree for C19orf68 (if available)
TreeFam:
Gene Tree for C19orf68 (if available)

Paralogs for C19orf68 Gene

No data available for Paralogs for C19orf68 Gene

Variants for C19orf68 Gene

Sequence variations from dbSNP and Humsavar for C19orf68 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs183902 -- 48,178,730(-) ggtgc(C/G)gtggc intron-variant
rs274867 -- 48,172,998(-) TCTCC(C/T)AGTCT intron-variant
rs274868 -- 48,174,463(-) GCAGC(A/G)CAATG intron-variant
rs274869 -- 48,174,891(-) AGTCT(C/T)GGATT intron-variant
rs274870 -- 48,175,757(-) ACTTC(A/G)AGAGA intron-variant

Relevant External Links for C19orf68 Gene

HapMap Linkage Disequilibrium report
C19orf68

No data available for Structural Variations from Database of Genomic Variants (DGV) for C19orf68 Gene

Disorders for C19orf68 Gene

Relevant External Links for C19orf68

Human Genome Epidemiology (HuGE) Navigator
C19orf68
genes like me logo Genes that share disorders with C19orf68: view

No data available for UniProtKB/Swiss-Prot for C19orf68 Gene

Publications for C19orf68 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. Association between genetic variants in VEGF, ERCC3 and occupational benzene haematotoxicity. (PMID: 19773279) Hosgood H.D. … Lan Q. (Occup Environ Med 2009) 3
  3. A comprehensive resource of interacting protein regions for refining human transcription factor networks. (PMID: 20195357) Miyamoto-Sato E. … Yanagawa H. (PLoS ONE 2010) 3
  4. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3
  5. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PMID: 21906983) Kim W. … Gygi S.P. (Mol. Cell 2011) 3

Products for C19orf68 Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate C19orf68
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for C19orf68
    • Block miRNA regulation of C19orf68 using miScript Target Protectors

    Sources for C19orf68 Gene

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