Aliases for C19orf68 Gene
External Ids for C19orf68 Gene
- HGNC: 34495
- Entrez Gene: 374920
- Ensembl: ENSG00000185453
- UniProtKB: Q86XI8
Previous GeneCards Identifiers for C19orf68 Gene
- GC19P053366
- GC19P048673
- GC19P045057
Summaries for C19orf68 Gene
GeneCards Summary for C19orf68 Gene
C19orf68 (Chromosome 19 Open Reading Frame 68) is a Protein Coding gene.
No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C19orf68 Gene
Genomics for C19orf68 Gene
Regulatory Elements for C19orf68 Gene
Enhancers for C19orf68 Gene
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around C19orf68 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Location for C19orf68 Gene
- Chromosome:
- 19
- Start:
- 48,170,662 bp from pter
- End:
- 48,197,621 bp from pter
- Size:
- 26,960 bases
- Orientation:
- Plus strand
Genomic View for C19orf68 Gene
Genes around C19orf68 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 19q13.33 by Ensembl
- 19q13.33 by Entrez Gene
- 19q13.33 by HGNC
C19orf68 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for C19orf68 Gene
Proteins for C19orf68 Gene
-
Protein details for C19orf68 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q86XI8-CS068_HUMAN
- Recommended name:
- Uncharacterized protein C19orf68
- Protein Accession:
- Q86XI8
Protein attributes for C19orf68 Gene
- Size:
- 627 amino acids
- Molecular mass:
- 70073 Da
- Quaternary structure:
- No Data Available
- SequenceCaution:
-
- Sequence=AAH43386.1; Type=Erroneous initiation; Evidence={ECO:0000305};
Protein Expression for C19orf68 Gene
Post-translational modifications for C19orf68 Gene
Other Protein References for C19orf68 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for C19orf68
-
Abcam antibodies for C19orf68
- Invitrogen Antibodies for C19orf68
- Search GeneTex for Antibodies for C19orf68
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for C19orf68
- Origene Custom Protein Services for C19orf68
- Novus Biologicals proteins for C19orf68
- Search GeneTex for Proteins for C19orf68
Assay Products
No data available for DME Specific Peptides for C19orf68 Gene
Domains & Families for C19orf68 Gene
Graphical View of Domain Structure for InterPro Entry
No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C19orf68 Gene
Function for C19orf68 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | 20195357 |
| GO:0008270 | zinc ion binding | IEA | -- |
Phenotypes for C19orf68 Gene
- GenomeRNAi human phenotypes for C19orf68:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for C19orf68
-
- Search ViGene Biosciences for C19orf68
CRISPR Products
- Browse CRISPR knockouts for C19orf68
miRNA for C19orf68 Gene
- miRTarBase miRNAs that target C19orf68
-
- hsa-mir-6881-3p (MIRT710720)
- hsa-mir-6780a-3p (MIRT710721)
- hsa-mir-7111-3p (MIRT710722)
- hsa-mir-6845-3p (MIRT710723)
- hsa-mir-1976 (MIRT710724)
- hsa-mir-3653-5p (MIRT710725)
- hsa-mir-3667-3p (MIRT710726)
- hsa-mir-6893-3p (MIRT710727)
- hsa-mir-370-3p (MIRT710728)
- hsa-mir-6769b-3p (MIRT710729)
- hsa-mir-4723-3p (MIRT710730)
- hsa-mir-3183 (MIRT710731)
- hsa-mir-5088-3p (MIRT710732)
- hsa-mir-1247-5p (MIRT710733)
- hsa-mir-1238-3p (MIRT714146)
- hsa-mir-670-3p (MIRT714147)
- hsa-mir-3679-3p (MIRT714148)
- hsa-mir-6891-3p (MIRT714149)
- hsa-mir-6072 (MIRT714150)
- hsa-mir-361-3p (MIRT714151)
- hsa-mir-208b-5p (MIRT714152)
- hsa-mir-208a-5p (MIRT714153)
miRNA Products
- Search ViGene Biosciences for C19orf68
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for C19orf68
- Browse OriGene Inhibitory RNA Products For C19orf68
- Search ViGene Biosciences for C19orf68
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for C19orf68
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for C19orf68
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C19orf68 Gene
Localization for C19orf68 Gene
| Compartment | Confidence |
|---|---|
| nucleus | 3 |
| cytosol | 2 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IEA | -- |
No data available for Subcellular locations from UniProtKB/Swiss-Prot for C19orf68 Gene
Pathways & Interactions for C19orf68 Gene
No Data Available
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006511 | ubiquitin-dependent protein catabolic process | IEA | -- |
| GO:0007275 | multicellular organism development | IEA | -- |
No data available for Pathways by source and SIGNOR curated interactions for C19orf68 Gene
Transcripts for C19orf68 Gene
mRNA/cDNA for C19orf68 Gene
- (6) REFSEQ mRNAs :
- (3) Additional mRNA sequences :
- (20) Selected AceView cDNA sequences:
- (3) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for C19orf68 Gene
CRISPR Products
- Browse CRISPR knockouts for C19orf68
miRNA Products
- Search ViGene Biosciences for C19orf68
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for C19orf68
- Browse OriGene Inhibitory RNA Products For C19orf68
- Search ViGene Biosciences for C19orf68
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for C19orf68
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for C19orf68
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
Expression for C19orf68 Gene
This gene is overexpressed in Testis (23.0), Liver, secretome (22.0), and Peripheral blood mononuclear cells (21.2).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C19orf68 Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of C19orf68 Gene:
C19orf68SOURCE GeneReport for Unigene cluster for C19orf68 Gene:
Hs.664054Evidence on tissue expression from TISSUES for C19orf68 Gene
- Eye(4)
Primer Products
-
OriGene qPCR primer pairs for C19orf68
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for C19orf68 Gene
Orthologs for C19orf68 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | C19H19orf68 34 |
|
||
| C19orf68 35 |
|
OneToOne | |||
| cow (Bos Taurus) |
Mammalia | C19orf68 35 |
|
OneToOne | |
| C18H19orf68 34 |
|
||||
| dog (Canis familiaris) |
Mammalia | C1H19orf68 34 |
|
||
| C19orf68 35 |
|
OneToOne | |||
| mouse (Mus musculus) |
Mammalia | 6330408A02Rik 34 16 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | RGD1310257 34 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | C19orf68 35 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | C19orf68 35 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | C19orf68 35 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | 6330408a02rik 34 |
|
- Species where no ortholog for C19orf68 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
- zebrafish (Danio rerio)
Paralogs for C19orf68 Gene
No data available for Paralogs for C19orf68 Gene
Variants for C19orf68 Gene
| SNP ID | Clin | Chr 19 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000004962 | -- | 48,182,503(+) | AGCCC(A/G)CTGCG | reference, synonymous-codon | |
| rs1000013643 | -- | 48,183,367(+) | TGTGA(C/T)CCGCC | intron-variant | |
| rs1000025107 | -- | 48,179,140(+) | TCTGA(-/T)TTTTT | intron-variant, upstream-variant-2KB | |
| rs1000048604 | -- | 48,171,696(+) | TAGAG(G/T)CACCA | intron-variant, upstream-variant-2KB | |
| rs1000071585 | -- | 48,183,489(+) | GCAGA(C/G)GTAAC | intron-variant |
Gene Damage Index Score:
0.82;
17.21% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for C19orf68 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- C19orf68
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C19orf68 Gene
Disorders for C19orf68 Gene
Relevant External Links for C19orf68
No disorders were found for C19orf68 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C19orf68 Gene
Publications for C19orf68 Gene
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3 64
- A human interactome in three quantitative dimensions organized by stoichiometries and abundances. (PMID: 26496610) Hein M.Y. … Mann M. (Cell 2015) 3 64
- A comprehensive resource of interacting protein regions for refining human transcription factor networks. (PMID: 20195357) Miyamoto-Sato E. … Yanagawa H. (PLoS ONE 2010) 3 64
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 64
- Association between genetic variants in VEGF, ERCC3 and occupational benzene haematotoxicity. (PMID: 19773279) Hosgood H.D. … Lan Q. (Occup Environ Med 2009) 3 64
Products for C19orf68 Gene
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- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
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- Custom Antibody Services
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- Custom Assay Services
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for C19orf68
- Origene Custom Protein Services for C19orf68
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for C19orf68
- Browse OriGene Inhibitory RNA Products For C19orf68
- OriGene qPCR primer pairs for C19orf68
- Browse CRISPR knockouts for C19orf68
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- GenScript: Next-day shipping cDNA ORF clone for C19orf68 in any vector
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- Novus Biologicals Antibodies for C19orf68
- Novus Biologicals proteins for C19orf68
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Cyagen custom Knockout/knockin (KOKI) mouse models for C19orf68
- VectorBuilder custom plasmid, inducible vectors for C19orf68
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for C19orf68
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for C19orf68 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
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- (122) diseasecard
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- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
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- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer