Free for academic non-profit institutions. Other users need a Commercial license

Aliases for C19orf67 Gene

Aliases for C19orf67 Gene

  • Chromosome 19 Open Reading Frame 67 2 3 5

External Ids for C19orf67 Gene

Previous GeneCards Identifiers for C19orf67 Gene

  • GC19M014055
  • GC19M014191

Summaries for C19orf67 Gene

GeneCards Summary for C19orf67 Gene

C19orf67 (Chromosome 19 Open Reading Frame 67) is a Protein Coding gene.

Additional gene information for C19orf67 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C19orf67 Gene

Genomics for C19orf67 Gene

Regulatory Elements for C19orf67 Gene

Enhancers for C19orf67 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH19H014227 1.1 ENCODE dbSUPER 11.5 -142.4 -142375 0.7 ZNF493 ZNF138 ZNF354C ZNF202 ZNF680 SMAD5 ZC3H11A OVOL3 REST ZNF623 CCDC130 MRI1 ZNF333 RFX1 DCAF15 NOTCH3 DDX39A SYDE1 SNRPGP15 C19orf67
GH19H014085 0.7 dbSUPER 0.7 +0.2 218 0.8 HDAC1 DMAP1 ZKSCAN1 RARA CCNT2 CTBP1 POLR2A L3MBTL2 BHLHE40 NRF1 PRKACA C19orf67 GC19M014079
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around C19orf67 on UCSC Golden Path with GeneCards custom track

Genomic Locations for C19orf67 Gene

Genomic Locations for C19orf67 Gene
4,275 bases
Minus strand

Genomic View for C19orf67 Gene

Genes around C19orf67 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C19orf67 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C19orf67 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C19orf67 Gene

Proteins for C19orf67 Gene

  • Protein details for C19orf67 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    UPF0575 protein C19orf67
    Protein Accession:

    Protein attributes for C19orf67 Gene

    358 amino acids
    Molecular mass:
    39779 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C19orf67 Gene

Post-translational modifications for C19orf67 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C19orf67 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C19orf67 Gene

Domains & Families for C19orf67 Gene

Gene Families for C19orf67 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for C19orf67 Gene


Suggested Antigen Peptide Sequences for C19orf67 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the UPF0575 family.
  • Belongs to the UPF0575 family.
genes like me logo Genes that share domains with C19orf67: view

Function for C19orf67 Gene

genes like me logo Genes that share phenotypes with C19orf67: view

Animal Models for C19orf67 Gene

MGI Knock Outs for C19orf67:

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , miRNA , Transcription Factor Targets and HOMER Transcription for C19orf67 Gene

Localization for C19orf67 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C19orf67 gene
Compartment Confidence
nucleus 2
cytosol 2
extracellular 1
peroxisome 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for C19orf67 Gene

Pathways & Interactions for C19orf67 Gene

SuperPathways for C19orf67 Gene

No Data Available

Interacting Proteins for C19orf67 Gene

Gene Ontology (GO) - Biological Process for C19orf67 Gene


No data available for Pathways by source and SIGNOR curated interactions for C19orf67 Gene

Drugs & Compounds for C19orf67 Gene

No Compound Related Data Available

Transcripts for C19orf67 Gene

mRNA/cDNA for C19orf67 Gene

(2) REFSEQ mRNAs :
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for C19orf67 Gene

No ASD Table

Relevant External Links for C19orf67 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C19orf67 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for C19orf67 Gene

mRNA differential expression in normal tissues according to GTEx for C19orf67 Gene

This gene is overexpressed in Testis (x31.4).

NURSA nuclear receptor signaling pathways regulating expression of C19orf67 Gene:

genes like me logo Genes that share expression patterns with C19orf67: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for C19orf67 Gene

Orthologs for C19orf67 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C19orf67 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia C19H19orf67 33
  • 99.35 (n)
C19orf67 34
  • 99 (a)
(Canis familiaris)
Mammalia C19orf67 34
  • 90 (a)
(Bos Taurus)
Mammalia C19orf67 34
  • 89 (a)
C7H19orf67 33
  • 85.33 (n)
(Mus musculus)
Mammalia 1700067K01Rik 33 16 34
  • 81.67 (n)
(Rattus norvegicus)
Mammalia LOC686013 33
  • 78.97 (n)
(Monodelphis domestica)
Mammalia C19orf67 34
  • 66 (a)
(Anolis carolinensis)
Reptilia C19orf67 34
  • 61 (a)
(Danio rerio)
Actinopterygii si:ch211-214c7.5 33
  • 52.69 (n)
C1H19orf67 34
  • 35 (a)
Species where no ortholog for C19orf67 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C19orf67 Gene

Gene Tree for C19orf67 (if available)
Gene Tree for C19orf67 (if available)

Paralogs for C19orf67 Gene

No data available for Paralogs for C19orf67 Gene

Variants for C19orf67 Gene

Sequence variations from dbSNP and Humsavar for C19orf67 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs1000194596 -- 14,086,152(+) CTGGA(C/G)TCAAG upstream-variant-2KB, utr-variant-5-prime
rs1000527823 -- 14,086,342(+) CAGGC(A/T)GGACT upstream-variant-2KB
rs1000562963 -- 14,083,278(+) TCTGG(A/G)GTGGC reference, synonymous-codon
rs1000726785 -- 14,086,197(+) CCTCT(C/T)TTTTT upstream-variant-2KB
rs1000847630 -- 14,083,548(+) GGAAG(C/T)GTACA reference, missense

Structural Variations from Database of Genomic Variants (DGV) for C19orf67 Gene

Variant ID Type Subtype PubMed ID
nsv953980 CNV deletion 24416366
nsv833761 CNV loss 17160897
nsv828454 CNV gain 20364138
nsv828452 CNV loss 20364138
nsv578642 CNV gain 21841781
dgv49n68 CNV loss 17160897

Variation tolerance for C19orf67 Gene

Gene Damage Index Score: 1.52; 29.61% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C19orf67 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C19orf67 Gene

Disorders for C19orf67 Gene

Relevant External Links for C19orf67

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for C19orf67 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C19orf67 Gene

Publications for C19orf67 Gene

  1. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J … Lucas SM (Nature 2004) 3 4 60

Products for C19orf67 Gene

Sources for C19orf67 Gene

Loading form....