Free for academic non-profit institutions. Other users need a Commercial license

Aliases for C19orf66 Gene

Aliases for C19orf66 Gene

  • Chromosome 19 Open Reading Frame 66 2 3

External Ids for C19orf66 Gene

Previous GeneCards Identifiers for C19orf66 Gene

  • GC19P010196
  • GC19P009777

Summaries for C19orf66 Gene

GeneCards Summary for C19orf66 Gene

C19orf66 (Chromosome 19 Open Reading Frame 66) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C19orf66 Gene

Genomics for C19orf66 Gene

Regulatory Elements for C19orf66 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for C19orf66 Gene

10,086,119 bp from pter
10,093,252 bp from pter
7,134 bases
Plus strand

Genomic View for C19orf66 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for C19orf66 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C19orf66 Gene

Proteins for C19orf66 Gene

  • Protein details for C19orf66 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    UPF0515 protein C19orf66
    Protein Accession:
    Secondary Accessions:
    • A8MQT9
    • Q4G188
    • Q8IYH6
    • Q8N8V1

    Protein attributes for C19orf66 Gene

    291 amino acids
    Molecular mass:
    33110 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for C19orf66 Gene


neXtProt entry for C19orf66 Gene

Proteomics data for C19orf66 Gene at MOPED

Post-translational modifications for C19orf66 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C19orf66 Gene

No data available for DME Specific Peptides for C19orf66 Gene

Domains & Families for C19orf66 Gene

Protein Domains for C19orf66 Gene


Suggested Antigen Peptide Sequences for C19orf66 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the UPF0515 family.
  • Belongs to the UPF0515 family.
genes like me logo Genes that share domains with C19orf66: view

No data available for Gene Families for C19orf66 Gene

Function for C19orf66 Gene

Gene Ontology (GO) - Molecular Function for C19orf66 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with C19orf66: view

Phenotypes for C19orf66 Gene

genes like me logo Genes that share phenotypes with C19orf66: view

Animal Model Products

CRISPR Products

miRNA for C19orf66 Gene

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C19orf66

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targets and HOMER Transcription for C19orf66 Gene

Localization for C19orf66 Gene

Subcellular locations from

Jensen Localization Image for C19orf66 Gene COMPARTMENTS Subcellular localization image for C19orf66 gene
Compartment Confidence
cytosol 2
nucleus 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C19orf66 Gene

Pathways & Interactions for C19orf66 Gene

SuperPathways for C19orf66 Gene

No Data Available

Gene Ontology (GO) - Biological Process for C19orf66 Gene


No data available for Pathways by source and SIGNOR curated interactions for C19orf66 Gene

Drugs & Compounds for C19orf66 Gene

No Compound Related Data Available

Transcripts for C19orf66 Gene

Unigene Clusters for C19orf66 Gene

Chromosome 19 open reading frame 66:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C19orf66

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C19orf66 Gene

ExUns: 1 ^ 2a · 2b · 2c · 2d ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7a · 7b ^ 8a · 8b · 8c · 8d ^ 9 ^ 10
SP1: -
SP2: - - -
SP3: -
SP4: -
SP5: - - -
SP7: -

Relevant External Links for C19orf66 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C19orf66 Gene

mRNA expression in normal human tissues for C19orf66 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for C19orf66 Gene

This gene is overexpressed in Liver (x6.7).

Protein differential expression in normal tissues from HIPED for C19orf66 Gene

This gene is overexpressed in Peripheral blood mononuclear cells (14.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for C19orf66 Gene

SOURCE GeneReport for Unigene cluster for C19orf66 Gene Hs.655613

genes like me logo Genes that share expression patterns with C19orf66: view

Protein tissue co-expression partners for C19orf66 Gene

Primer Products

In Situ Assay Products

No data available for mRNA Expression by UniProt/SwissProt for C19orf66 Gene

Orthologs for C19orf66 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C19orf66 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia C7H19orf66 35
  • 91.21 (n)
  • 96.34 (a)
C7H19orf66 36
  • 95 (a)
(Canis familiaris)
Mammalia C20H19orf66 35
  • 90.96 (n)
  • 96.34 (a)
C19orf66 36
  • 95 (a)
(Mus musculus)
Mammalia A230050P20Rik 35
  • 84.94 (n)
  • 93.79 (a)
A230050P20Rik 16
A230050P20Rik 36
  • 96 (a)
(Pan troglodytes)
Mammalia C19H19orf66 35
  • 97.14 (n)
  • 96.9 (a)
C19ORF66 36
  • 100 (a)
(Rattus norvegicus)
Mammalia LOC500956 35
  • 85.28 (n)
  • 96.32 (a)
(Monodelphis domestica)
Mammalia C19orf66 36
  • 57 (a)
(Anolis carolinensis)
Reptilia C19orf66 36
  • 52 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia c19orf66 35
  • 61.22 (n)
  • 58.94 (a)
(Danio rerio)
Actinopterygii zgc:171711 35
  • 58.24 (n)
  • 54.72 (a)
C3H19orf66 36
  • 46 (a)
Species with no ortholog for C19orf66:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C19orf66 Gene

Gene Tree for C19orf66 (if available)
Gene Tree for C19orf66 (if available)

Paralogs for C19orf66 Gene

No data available for Paralogs for C19orf66 Gene

Variants for C19orf66 Gene

Sequence variations from dbSNP and Humsavar for C19orf66 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs1979262 -- 10,087,765(+) AGGCT(A/G)GGATG intron-variant
rs2227286 -- 10,087,083(+) GGTGC(G/T)GGGAC intron-variant
rs2232063 -- 10,085,674(+) ACCGG(A/G)CTACT upstream-variant-2KB
rs2232064 -- 10,089,726(+) TGGGG(C/G)AGTTG intron-variant, downstream-variant-500B
rs2232065 -- 10,089,781(+) GAGGG(C/G)AGATA intron-variant, downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for C19orf66 Gene

Variant ID Type Subtype PubMed ID
dgv3724n71 CNV Gain 21882294
nsv458355 CNV Loss 19166990
nsv2414 CNV Insertion 18451855
nsv833743 CNV Loss 17160897

Variation tolerance for C19orf66 Gene

Residual Variation Intolerance Score: 57.43% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.63; 13.52% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C19orf66 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C19orf66 Gene

Disorders for C19orf66 Gene

Relevant External Links for C19orf66

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with C19orf66: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C19orf66 Gene

Publications for C19orf66 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 67
  2. Phospho-tyrosine dependent protein-protein interaction network. (PMID: 25814554) Grossmann A. … Stelzl U. (Mol. Syst. Biol. 2015) 67
  3. An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. (PMID: 24275569) Bian Y. … Zou H. (J. Proteomics 2014) 67
  4. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 67
  5. N-terminal acetylome analyses and functional insights of the N- terminal acetyltransferase NatB. (PMID: 22814378) Van Damme P. … Aldabe R. (Proc. Natl. Acad. Sci. U.S.A. 2012) 67

Products for C19orf66 Gene

Sources for C19orf66 Gene

Back to Top