Free for academic non-profit institutions. Other users need a Commercial license

Aliases for C19orf60 Gene

Aliases for C19orf60 Gene

  • Chromosome 19 Open Reading Frame 60 2 3 5

External Ids for C19orf60 Gene

Previous GeneCards Identifiers for C19orf60 Gene

  • GC19P018561
  • GC19P018699
  • GC19P018262

Summaries for C19orf60 Gene

GeneCards Summary for C19orf60 Gene

C19orf60 (Chromosome 19 Open Reading Frame 60) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C19orf60 Gene

Genomics for C19orf60 Gene

Regulatory Elements for C19orf60 Gene

Promoters for C19orf60 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around C19orf60 on UCSC Golden Path with GeneCards custom track

Genomic Location for C19orf60 Gene

Chromosome:
19
Start:
18,588,685 bp from pter
End:
18,592,337 bp from pter
Size:
3,653 bases
Orientation:
Plus strand

Genomic View for C19orf60 Gene

Genes around C19orf60 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C19orf60 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C19orf60 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C19orf60 Gene

Proteins for C19orf60 Gene

  • Protein details for C19orf60 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96EN9-CS060_HUMAN
    Recommended name:
    Uncharacterized protein C19orf60
    Protein Accession:
    Q96EN9
    Secondary Accessions:
    • E9PAS0
    • Q8NAX4
    • Q9NWI0

    Protein attributes for C19orf60 Gene

    Size:
    201 amino acids
    Molecular mass:
    22599 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAA91400.1; Type=Frameshift; Positions=107; Evidence={ECO:0000305};

    Alternative splice isoforms for C19orf60 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for C19orf60 Gene

Proteomics data for C19orf60 Gene at MOPED

Post-translational modifications for C19orf60 Gene

No Post-translational modifications

Other Protein References for C19orf60 Gene

No data available for DME Specific Peptides for C19orf60 Gene

Domains & Families for C19orf60 Gene

Protein Domains for C19orf60 Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C19orf60: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C19orf60 Gene

Function for C19orf60 Gene

genes like me logo Genes that share phenotypes with C19orf60: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for C19orf60 Gene

Localization for C19orf60 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for C19orf60 Gene COMPARTMENTS Subcellular localization image for C19orf60 gene
Compartment Confidence
cytosol 2
nucleus 2
extracellular 1
mitochondrion 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C19orf60 Gene

Pathways & Interactions for C19orf60 Gene

SuperPathways for C19orf60 Gene

No Data Available

Gene Ontology (GO) - Biological Process for C19orf60 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C19orf60 Gene

Drugs & Compounds for C19orf60 Gene

No Compound Related Data Available

Transcripts for C19orf60 Gene

Unigene Clusters for C19orf60 Gene

Chromosome 19 open reading frame 60:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for C19orf60 Gene

ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3a · 3b · 3c · 3d ^ 4 ^ 5a · 5b ^ 6a · 6b · 6c · 6d
SP1: - - - -
SP2: - - - - -
SP3: - - - - - - -
SP4:
SP5: - - -
SP6: - -
SP7: -

Relevant External Links for C19orf60 Gene

GeneLoc Exon Structure for
C19orf60
ECgene alternative splicing isoforms for
C19orf60

Expression for C19orf60 Gene

mRNA expression in normal human tissues for C19orf60 Gene

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MOPED, and MaxQB for C19orf60 Gene



SOURCE GeneReport for Unigene cluster for C19orf60 Gene Hs.655317

genes like me logo Genes that share expression patterns with C19orf60: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for C19orf60 Gene

Orthologs for C19orf60 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C19orf60 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia C7H19orf60 35
  • 85.29 (n)
  • 81.56 (a)
C19orf60 36
  • 82 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C20H19orf60 35
  • 84.17 (n)
  • 79.89 (a)
C19orf60 36
  • 78 (a)
OneToOne
mouse
(Mus musculus)
Mammalia 2810428I15Rik 35
  • 80.5 (n)
  • 73.58 (a)
2810428I15Rik 16
2810428I15Rik 36
  • 70 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia C19H19orf60 35
  • 98.84 (n)
  • 98.01 (a)
C19ORF60 36
  • 98 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia RGD1566239 35
  • 76.36 (n)
  • 70.91 (a)
zebrafish
(Danio rerio)
Actinopterygii C22H19orf60 36
  • 31 (a)
OneToOne
Species with no ortholog for C19orf60:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C19orf60 Gene

ENSEMBL:
Gene Tree for C19orf60 (if available)
TreeFam:
Gene Tree for C19orf60 (if available)

Paralogs for C19orf60 Gene

No data available for Paralogs for C19orf60 Gene

Variants for C19orf60 Gene

Sequence variations from dbSNP and Humsavar for C19orf60 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs2002632 -- 18,591,864(-) GTAAT(C/T)CAGCA intron-variant
rs1129208 -- 18,592,314(+) CTCCC(A/C)CAATA utr-variant-3-prime
rs2074174 -- 18,589,180(+) TTGTG(C/T)GGCTG intron-variant, upstream-variant-2KB
rs2074175 -- 18,589,237(+) CACGA(A/G)AAAGG intron-variant, reference, missense
rs2074176 -- 18,589,978(+) TCCAC(C/T)CACTC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C19orf60 Gene

Variant ID Type Subtype PubMed ID
nsv911281 CNV Loss 21882294
nsv911282 CNV Loss 21882294
nsv833776 CNV Loss 17160897
dgv3784n71 CNV Loss 21882294
dgv3785n71 CNV Loss 21882294
nsv911288 CNV Loss 21882294
nsv911290 CNV Loss 21882294

Variation tolerance for C19orf60 Gene

Gene Damage Index Score: 1.02; 20.88% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C19orf60 Gene

HapMap Linkage Disequilibrium report
C19orf60

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C19orf60 Gene

Disorders for C19orf60 Gene

Relevant External Links for C19orf60

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C19orf60

No disorders were found for C19orf60 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C19orf60 Gene

Publications for C19orf60 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 67
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  4. A directed protein interaction network for investigating intracellular signal transduction. (PMID: 21900206) Vinayagam A. … Wanker E.E. (Sci Signal 2011) 3
  5. An empirical framework for binary interactome mapping. (PMID: 19060904) Venkatesan K. … Vidal M. (Nat. Methods 2009) 3

Products for C19orf60 Gene

Sources for C19orf60 Gene

Back to Top

Content