Aliases for C19orf60 Gene
External Ids for C19orf60 Gene
- HGNC: 26098
- Entrez Gene: 55049
- Ensembl: ENSG00000006015
- UniProtKB: Q96EN9
Previous GeneCards Identifiers for C19orf60 Gene
- GC19P018561
- GC19P018699
- GC19P018262
Summaries for C19orf60 Gene
GeneCards Summary for C19orf60 Gene
C19orf60 (Chromosome 19 Open Reading Frame 60) is a Protein Coding gene.
No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C19orf60 Gene
Genomics for C19orf60 Gene
Regulatory Elements for C19orf60 Gene
Enhancers for C19orf60 Gene
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around C19orf60 on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the C19orf60 gene promoter:
Regulatory Element Products
Genomic Location for C19orf60 Gene
- Chromosome:
- 19
- Start:
- 18,588,685 bp from pter
- End:
- 18,592,337 bp from pter
- Size:
- 3,653 bases
- Orientation:
- Plus strand
Genomic View for C19orf60 Gene
Genes around C19orf60 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 19p13.11 by Ensembl
- 19p13.11 by Entrez Gene
- 19p13.11 by HGNC
C19orf60 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for C19orf60 Gene
Proteins for C19orf60 Gene
-
Protein details for C19orf60 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q96EN9-CS060_HUMAN
- Recommended name:
- Uncharacterized protein C19orf60
- Protein Accession:
- Q96EN9
- E9PAS0
- Q8NAX4
- Q9NWI0
Protein attributes for C19orf60 Gene
- Size:
- 201 amino acids
- Molecular mass:
- 22599 Da
- Quaternary structure:
- No Data Available
- SequenceCaution:
-
- Sequence=BAA91400.1; Type=Frameshift; Positions=107; Evidence={ECO:0000305};
Protein Expression for C19orf60 Gene
Post-translational modifications for C19orf60 Gene
Other Protein References for C19orf60 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for C19orf60
-
Abcam antibodies for C19orf60
- Invitrogen Antibodies for C19orf60
- Search GeneTex for Antibodies for C19orf60
Protein Products
-
OriGene Purified Proteins for C19orf60
- Search Origene for MassSpec and Protein Over-expression Lysates for C19orf60
- Origene Custom Protein Services for C19orf60
- Search GeneTex for Proteins for C19orf60
Assay Products
No data available for DME Specific Peptides for C19orf60 Gene
Domains & Families for C19orf60 Gene
Protein Domains for C19orf60 Gene
- ProtoNet:
Graphical View of Domain Structure for InterPro Entry
No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C19orf60 Gene
Function for C19orf60 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | 16189514 |
Phenotypes for C19orf60 Gene
- GenomeRNAi human phenotypes for C19orf60:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for C19orf60
-
-
ViGene Biosciences lentiviral particle packaged cDNA for C19orf60 gene
- Search ViGene Biosciences for C19orf60
CRISPR Products
-
OriGene CRISPR knockouts for C19orf60
-
Santa Cruz Biotechnology (SCBT) CRISPR for C19orf60
- GenScript: Design CRISPR guide RNA sequences for C19orf60
miRNA Products
- Search ViGene Biosciences for C19orf60
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for C19orf60
- Browse OriGene Inhibitory RNA Products For C19orf60
- Search ViGene Biosciences for C19orf60
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for C19orf60
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for C19orf60
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for C19orf60
-
ViGene Biosciences adenoviral particle packaged cDNA for C19orf60 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for C19orf60 gene
- Search ViGene Biosciences for C19orf60
Flow Cytometry Products
No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for C19orf60 Gene
Localization for C19orf60 Gene
| Compartment | Confidence |
|---|---|
| nucleus | 2 |
| cytosol | 2 |
| extracellular | 1 |
| mitochondrion | 1 |
No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C19orf60 Gene
Pathways & Interactions for C19orf60 Gene
No Data Available
Interacting Proteins for C19orf60 Gene
Selected Interacting proteins:
Q96EN9-CS060_HUMAN
ENSP00000351422
for C19orf60 Gene via
MINT
STRING
UniProtKB
IID
No data available for Pathways by source and SIGNOR curated interactions for C19orf60 Gene
Transcripts for C19orf60 Gene
mRNA/cDNA for C19orf60 Gene
- (4) REFSEQ mRNAs :
- (5) Additional mRNA sequences :
- (173) Selected AceView cDNA sequences:
- (8) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for C19orf60 Gene
CRISPR Products
-
OriGene CRISPR knockouts for C19orf60
-
Santa Cruz Biotechnology (SCBT) CRISPR for C19orf60
- GenScript: Design CRISPR guide RNA sequences for C19orf60
miRNA Products
- Search ViGene Biosciences for C19orf60
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for C19orf60
- Browse OriGene Inhibitory RNA Products For C19orf60
- Search ViGene Biosciences for C19orf60
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for C19orf60
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for C19orf60
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2 | ^ | 3a | · | 3b | · | 3c | · | 3d | ^ | 4 | ^ | 5a | · | 5b | ^ | 6a | · | 6b | · | 6c | · | 6d |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | |||||||||||||||||||||||||||
| SP2: | - | - | - | - | - | ||||||||||||||||||||||||||
| SP3: | - | - | - | - | - | - | - | ||||||||||||||||||||||||
| SP4: | |||||||||||||||||||||||||||||||
| SP5: | - | - | - | ||||||||||||||||||||||||||||
| SP6: | - | - | |||||||||||||||||||||||||||||
| SP7: | - |
Expression for C19orf60 Gene
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for C19orf60 Gene
NURSA nuclear receptor signaling pathways regulating expression of C19orf60 Gene:
C19orf60SOURCE GeneReport for Unigene cluster for C19orf60 Gene:
Hs.655317Evidence on tissue expression from TISSUES for C19orf60 Gene
- Nervous system(3.2)
- Muscle(2.2)
Primer Products
-
OriGene qPCR primer pairs for C19orf60
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for C19orf60 Gene
Orthologs for C19orf60 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | C19H19orf60 34 |
|
||
| C19ORF60 35 |
|
OneToOne | |||
| cow (Bos Taurus) |
Mammalia | C7H19orf60 34 |
|
||
| C19orf60 35 |
|
OneToOne | |||
| dog (Canis familiaris) |
Mammalia | C20H19orf60 34 |
|
||
| C19orf60 35 |
|
OneToOne | |||
| mouse (Mus musculus) |
Mammalia | 2810428I15Rik 34 16 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | RGD1566239 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | C22H19orf60 35 |
|
OneToOne |
- Species where no ortholog for C19orf60 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- lizard (Anolis carolinensis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- oppossum (Monodelphis domestica)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for C19orf60 Gene
No data available for Paralogs for C19orf60 Gene
Variants for C19orf60 Gene
| SNP ID | Clin | Chr 19 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000758766 | -- | 18,589,973(+) | AATGC(A/T)CCACC | intron-variant | |
| rs1001735680 | -- | 18,588,405(+) | GACTG(C/G)AGGCG | upstream-variant-2KB | |
| rs1002154207 | -- | 18,590,735(+) | CCCTC(C/G)TGGTT | intron-variant | |
| rs1002749473 | -- | 18,592,268(+) | GGGTT(A/G)CGCCC | utr-variant-3-prime | |
| rs1002803966 | -- | 18,592,616(+) | TTAAT(G/T)TTTTT | downstream-variant-500B |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv3643841 | CNV | loss | 21293372 |
| nsv833776 | CNV | loss | 17160897 |
Gene Damage Index Score:
1.02;
20.88% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for C19orf60 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- C19orf60
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C19orf60 Gene
Disorders for C19orf60 Gene
Relevant External Links for C19orf60
- Atlas of Genetics and Cytogenetics in Oncology and Haematology:
- C19orf60
No disorders were found for C19orf60 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C19orf60 Gene
Publications for C19orf60 Gene
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3 64
- The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3 64
- A human interactome in three quantitative dimensions organized by stoichiometries and abundances. (PMID: 26496610) Hein M.Y. … Mann M. (Cell 2015) 3 64
- N-terminal acetylome analyses and functional insights of the N- terminal acetyltransferase NatB. (PMID: 22814378) Van Damme P. … Aldabe R. (Proc. Natl. Acad. Sci. U.S.A. 2012) 4 64
Products for C19orf60 Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Browse OriGene Antibodies
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for C19orf60
- Search Origene for MassSpec and Protein Over-expression Lysates for C19orf60
- Origene Custom Protein Services for C19orf60
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for C19orf60
- Browse OriGene Inhibitory RNA Products For C19orf60
- OriGene qPCR primer pairs for C19orf60
- OriGene CRISPR knockouts for C19orf60
- OriGene ORF clones in human for C19orf60
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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- GenScript: Next-day shipping cDNA ORF clone for C19orf60 in any vector
- GenScript Custom Purified and Recombinant Proteins Services for C19orf60
- GenScript Custom Assay Services for C19orf60
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- GenScript: Design CRISPR guide RNA sequences for C19orf60
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
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- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
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- Browse Sino Biological cDNA Clones
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- Sino Biological Antibodies
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- Sino Biological Cell Lysates
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- Sino Biological Transfection Reagents
- Novus Biologicals Antibodies for C19orf60
- Novus Biologicals proteins and lysates for C19orf60
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- ViGene Biosciences adenoviral particle packaged cDNA for C19orf60 gene
- ViGene Biosciences lentiviral particle packaged cDNA for C19orf60 gene
- Search ViGene Biosciences for C19orf60
- Horizon Cell Lines for C19orf60
- Cyagen custom Knockout/knockin (KOKI) mouse models for C19orf60
- VectorBuilder custom plasmid, inducible vectors for C19orf60
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for C19orf60
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for C19orf60 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer