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Aliases for C19orf60 Gene

Aliases for C19orf60 Gene

  • Chromosome 19 Open Reading Frame 60 2 3 5

External Ids for C19orf60 Gene

Previous GeneCards Identifiers for C19orf60 Gene

  • GC19P018561
  • GC19P018699
  • GC19P018262

Summaries for C19orf60 Gene

GeneCards Summary for C19orf60 Gene

C19orf60 (Chromosome 19 Open Reading Frame 60) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C19orf60 Gene

Genomics for C19orf60 Gene

Regulatory Elements for C19orf60 Gene

Enhancers for C19orf60 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH19F018587 0.5 ENCODE 13 +0.8 755 3.6 HDGF PKNOX1 ARNT CREB3L1 MLX ARID4B SIN3A FEZF1 DMAP1 ZNF2 ENSG00000268030 KXD1 UBA52 ENSG00000268938 C19orf60 UPF1 ENSG00000268199 ENSG00000269191 RFXANK CRLF1
GH19F018492 1.3 FANTOM5 Ensembl ENCODE 11.9 -87.3 -87285 18.8 MLX ARID4B DMAP1 ZNF2 YY1 ZNF143 ZNF263 SP3 SP5 NFYC ELL SSBP4 FKBP8 UBA52 CRTC1 KXD1 C19orf60 ARRDC2 JUND IL12RB1
GH19F018472 1.2 FANTOM5 Ensembl ENCODE 11.8 -107.3 -107297 16.8 MLX CREB3L1 FEZF1 DMAP1 YY1 SLC30A9 ZNF143 ZNF263 SP3 NFYC KXD1 IFI30 ENSG00000268030 SSBP4 ELL ENSG00000268938 UBA52 UPF1 CRTC1 C19orf60
GH19F018846 0.9 Ensembl ENCODE 11.7 +260.1 260076 5.2 CBX3 TBL1XR1 SIN3A ARID4B ZNF2 RAD21 EGR1 ZNF143 ETV6 DEK COMP C19orf60 ENSG00000269694 LOC102724360 GC19P019013 PIR45819 UPF1
GH19F018671 0.7 Ensembl ENCODE 11.6 +83.9 83903 1.5 CTCF POLR2A REST RAD21 C19orf60 CRTC1 SNORA68 TMEM59L KLHL26
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around C19orf60 on UCSC Golden Path with GeneCards custom track

Promoters for C19orf60 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000344720 915 2401 HDGF PKNOX1 ARNT CREB3L1 MLX ARID4B SIN3A FEZF1 DMAP1 ZNF2

Genomic Location for C19orf60 Gene

Chromosome:
19
Start:
18,588,685 bp from pter
End:
18,592,337 bp from pter
Size:
3,653 bases
Orientation:
Plus strand

Genomic View for C19orf60 Gene

Genes around C19orf60 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C19orf60 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C19orf60 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C19orf60 Gene

Proteins for C19orf60 Gene

  • Protein details for C19orf60 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96EN9-CS060_HUMAN
    Recommended name:
    Uncharacterized protein C19orf60
    Protein Accession:
    Q96EN9
    Secondary Accessions:
    • E9PAS0
    • Q8NAX4
    • Q9NWI0

    Protein attributes for C19orf60 Gene

    Size:
    201 amino acids
    Molecular mass:
    22599 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAA91400.1; Type=Frameshift; Positions=107; Evidence={ECO:0000305};

    Alternative splice isoforms for C19orf60 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for C19orf60 Gene

Post-translational modifications for C19orf60 Gene

No Post-translational modifications

Other Protein References for C19orf60 Gene

No data available for DME Specific Peptides for C19orf60 Gene

Domains & Families for C19orf60 Gene

Protein Domains for C19orf60 Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C19orf60: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C19orf60 Gene

Function for C19orf60 Gene

Gene Ontology (GO) - Molecular Function for C19orf60 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 16189514
genes like me logo Genes that share ontologies with C19orf60: view
genes like me logo Genes that share phenotypes with C19orf60: view

Animal Model Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for C19orf60 Gene

Localization for C19orf60 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for C19orf60 Gene COMPARTMENTS Subcellular localization image for C19orf60 gene
Compartment Confidence
cytosol 2
nucleus 2
extracellular 1
mitochondrion 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C19orf60 Gene

Pathways & Interactions for C19orf60 Gene

SuperPathways for C19orf60 Gene

No Data Available

Gene Ontology (GO) - Biological Process for C19orf60 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C19orf60 Gene

Transcripts for C19orf60 Gene

Unigene Clusters for C19orf60 Gene

Chromosome 19 open reading frame 60:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C19orf60 Gene

ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3a · 3b · 3c · 3d ^ 4 ^ 5a · 5b ^ 6a · 6b · 6c · 6d
SP1: - - - -
SP2: - - - - -
SP3: - - - - - - -
SP4:
SP5: - - -
SP6: - -
SP7: -

Relevant External Links for C19orf60 Gene

GeneLoc Exon Structure for
C19orf60
ECgene alternative splicing isoforms for
C19orf60

Expression for C19orf60 Gene

mRNA expression in normal human tissues for C19orf60 Gene

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for C19orf60 Gene



NURSA nuclear receptor signaling pathways regulating expression of C19orf60 Gene:

C19orf60

SOURCE GeneReport for Unigene cluster for C19orf60 Gene:

Hs.655317
genes like me logo Genes that share expression patterns with C19orf60: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for C19orf60 Gene

Orthologs for C19orf60 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C19orf60 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C19H19orf60 34
  • 98.84 (n)
C19ORF60 35
  • 98 (a)
OneToOne
cow
(Bos Taurus)
Mammalia C7H19orf60 34
  • 85.29 (n)
C19orf60 35
  • 82 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C20H19orf60 34
  • 84.17 (n)
C19orf60 35
  • 78 (a)
OneToOne
mouse
(Mus musculus)
Mammalia 2810428I15Rik 34 16 35
  • 80.5 (n)
rat
(Rattus norvegicus)
Mammalia RGD1566239 34
  • 76.36 (n)
zebrafish
(Danio rerio)
Actinopterygii C22H19orf60 35
  • 31 (a)
OneToOne
Species where no ortholog for C19orf60 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C19orf60 Gene

ENSEMBL:
Gene Tree for C19orf60 (if available)
TreeFam:
Gene Tree for C19orf60 (if available)

Paralogs for C19orf60 Gene

No data available for Paralogs for C19orf60 Gene

Variants for C19orf60 Gene

Sequence variations from dbSNP and Humsavar for C19orf60 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs10402109 -- 18,587,612(+) acaaa(A/C)aaaAA upstream-variant-2KB
rs10403184 -- 18,591,647(+) tttga(C/G)ataga intron-variant
rs10407212 -- 18,588,635(+) TGGAC(A/G)GGAAC upstream-variant-2KB
rs10407322 -- 18,587,411(+) aaccc(C/T)gcctc upstream-variant-2KB
rs10409392 -- 18,588,523(+) CTTCA(A/C)GTGGA upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for C19orf60 Gene

Variant ID Type Subtype PubMed ID
esv3643841 CNV loss 21293372
nsv833776 CNV loss 17160897

Variation tolerance for C19orf60 Gene

Gene Damage Index Score: 1.02; 20.88% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C19orf60 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
C19orf60

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C19orf60 Gene

Disorders for C19orf60 Gene

Relevant External Links for C19orf60

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C19orf60

No disorders were found for C19orf60 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C19orf60 Gene

Publications for C19orf60 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3 64
  3. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3 64
  4. A human interactome in three quantitative dimensions organized by stoichiometries and abundances. (PMID: 26496610) Hein M.Y. … Mann M. (Cell 2015) 3 64
  5. N-terminal acetylome analyses and functional insights of the N- terminal acetyltransferase NatB. (PMID: 22814378) Van Damme P. … Aldabe R. (Proc. Natl. Acad. Sci. U.S.A. 2012) 4 64

Products for C19orf60 Gene

Sources for C19orf60 Gene

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