C19orf60 Gene
protein-coding GIFtS: 38
GCID: GC19P018699
|
|
chromosome 19 open reading frame 60
| |
Aliases
for C19orf60 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Chromosome 19 Open Reading Frame 601 2 | | FLJ208501 | | FLJ301081 | | FLJ346061 | | FLJ373911 | | Uncharacterized Protein C19orf602 |
Export aliases for C19orf60 gene to outside databasesPrevious GC identifers: GC19P018561 GC19P018262 |
Summaries
for C19orf60 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for C19orf60 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000019.9 NC_018930.1 NT_011295.11
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the C19orf60 gene promoter:
AhR Lmo2 AP-4 HNF-4alpha2 AP-2gamma Arnt HNF-4alpha1 CREB NF-kappaB1 MRF-2
Other transcription factors
Search SABiosciences Chromatin IP Primers for C19orf60
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C19orf60 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 19p13.11 Ensembl cytogenetic band: 19p13.11 HGNC cytogenetic band: 19p13.11C19orf60 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19P018699: view genomic region
(about GC identifiers)
Start:
|
18,699,495 bp from pter |
End:
|
18,703,147 bp from pter |
Size:
|
3,653 bases |
Orientation:
|
plus strand |
|
Proteins
for C19orf60 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CS060_HUMAN, Q96EN9 (See
protein sequence)Recommended Name: Uncharacterized protein C19orf60 Size: 201 amino acids; 22599 Da
Sequence caution: Sequence=BAA91400.1; Type=Frameshift; Positions=107;
Secondary accessions: Q8NAX4 Q9NWI0Alternative splicing: 2 isoforms: Q96EN9-1 Q96EN9-2 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for C19orf60: NX_Q96EN9
C19orf60 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001093888.1 NP_001093889.1
ENSEMBL proteins: ENSP00000351422 ENSP00000398467
Human Recombinant Protein Products:
C19orf60 Antibody Products:
Assay Products for C19orf60: |
Protein
Domains /
Families
for C19orf60 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: Q96EN9 |
Function
for C19orf60 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C19orf60 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C19orf60 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): C19orf60 (NM_001100419) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for C19orf60 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C19orf60 |
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table
C19orf60 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for C19orf60:
|
Pathways & Interactions
for C19orf60 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for C19orf60
STRING Interaction
Network Preview (showing 3 interactants - click image to see more details)
5/7 Interacting proteins for C19orf60 (Q96EN91, 2, 3 ENSP000003514224) via UniProtKB, MINT, STRING, and/or I2D (see all 7)About this table
|
Drugs & Compounds
for C19orf60 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for C19orf60
Search CenterWatch for drugs/clinical trials and news about C19orf60 / CS060
|
Transcripts
for C19orf60 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for C19orf60 gene (3 alternative transcripts): NM_017967.2 NM_001100418.1 NM_001100419.1 Unigene Cluster for C19orf60: Chromosome 19 open reading frame 60 Hs.655317 [show with all ESTs]Unigene Representative Sequence: AK0947102 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000358607(uc002nju.2 uc002njv.4) ENST00000450195(uc010ebs.3)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C19orf60 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C19orf60 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): C19orf60 (NM_001100419) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for C19orf60 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C19orf60 |
Additional cDNA sequence: AK000857.1 AK054670.1 AK091925.1 AK094710.1 BC012078.1 16 DOTS entries: DT.100845537 DT.86852028 DT.121499149 DT.95189254 DT.40111085 DT.100845535 DT.121499185 DT.102838526 DT.75168885 DT.100026653 DT.100845538 DT.95189260 DT.95189261 DT.121499147 DT.100845534 DT.95293310 24/173 AceView cDNA sequences (see all 173): BU844497 CK299281 BM128521 BF591405 CB177427 CR625418 CB137039 AI433538 AI223191 AV707942 CB047779 CD673861 AW075602 BF939241 CB155247 D20857 CA422953 CR616719 AI380546 BC012078 BM725708 AI874272 AI431740 BU631876
GeneLoc Exon Structure
5/7 Alternative Splicing Database (ASD) splice patterns (SP) for C19orf60 (see all 7) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2 | ^ | 3a | · | 3b | · | 3c | · | 3d | ^ | 4 | ^ | 5a | · | 5b | ^ | 6a | · | 6b | · | 6c | · | 6d |
|---|
|
| SP1: | | | | | | | | | | | - | | | | | | | | - | | - | | | | - | | | | | | | | |
| SP2: | | | | | | | | | | | - | | - | | | | | | - | | - | | | | - | | | | | | | | |
| SP3: | | | | | | | | | | | - | | - | | - | | - | | - | | - | | | | - | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | - | | - | | | | - | | | | | | | |
ECgene alternative splicing isoforms for C19orf60
|
Expression
for C19orf60 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| C19orf60 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GAGGCGATCA
About this image
See C19orf60 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for C19orf60
SOURCE GeneReport for Unigene cluster: Hs.655317
SABiosciences Custom PCR Arrays for C19orf60
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C19orf60
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat C19orf60 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C19orf60 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C19orf60 |
Orthologs
for C19orf60 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for C19orf60 gene from 3/9 species (see all 9) About this table
ENSEMBL Gene Tree for C19orf60 (if available)
TreeFam Gene Tree for C19orf60 (if available) |
Paralogs
for C19orf60 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for C19orf60 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 19 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for C19orf60 (18699495 - 18703147 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for C19orf60: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing C19orf60 |
|
Disorders
/ Diseases
for C19orf60 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for C19orf60 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for C19orf60 gene integrated from 9 sources:
(articles sorted by number of sources associating them with C19orf60) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
- A directed protein interaction network for investigat ing intracellular signal transduction. (PubMed id 21900206)1 Vinayagam A....Wanker E.E. (2011)
- A novel human protein is able to interact with hepati tis B virus core deletion mutant but not with the wild-type protein. (PubMed id 19770013)1 Razanskas R. and Sasnauskas K. (2009)
- An empirical framework for binary interactome mapping . (PubMed id 19060904)1 Venkatesan K....Vidal M. (2009)
- Defining the human deubiquitinating enzyme interactio n landscape. (PubMed id 19615732)1 Sowa M.E....Harper J.W. (2009)
- hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (2007)
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
- Towards a proteome-scale map of the human protein-protein interaction network. (PubMed id 16189514)1 Rual J.F....Vidal M. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
|
External Searches for C19orf60 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing C19orf60 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing C19orf60 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing C19orf60 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for C19orf60 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for C19orf60 gene:
Search GeneIP for patents involving C19orf60
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for C19orf60 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for C19orf60 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for C19orf60 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C19orf60 | | | OriGene Protein Over-expression Lysate for C19orf60 | | Browse OriGene Fluorogenic Cell Assay Kits | | | Browse OriGene siRNAs | | OriGene 3'-UTR Clone for C19orf60 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C19orf60 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C19orf60 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for C19orf60 | | OriGene Custom Protein Services for C19orf60 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat C19orf60 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing C19orf60 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C19orf60 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat C19orf60 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C19orf60 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C19orf60 |
| |
 |  |  |  | |
| | | |  |  |  |  | | | | |
 |
 |
 |
 | | | C19orf60 Proteins, Antibodies, CLIAs, and ELISAs |
| | | |  |  |  | | | | Search ThermoFisher Antibodies for C19orf60 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C19orf60 |
|
|
|
|
