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Aliases for C19orf57 Gene

Aliases for C19orf57 Gene

  • Chromosome 19 Open Reading Frame 57 2 3
  • Pre-T/NK Cell-Associated Protein 3B3 4

External Ids for C19orf57 Gene

Previous GeneCards Identifiers for C19orf57 Gene

  • GC19M013855
  • GC19M013856
  • GC19M013993
  • GC19M013564

Summaries for C19orf57 Gene

GeneCards Summary for C19orf57 Gene

C19orf57 (Chromosome 19 Open Reading Frame 57) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C19orf57 Gene

Genomics for C19orf57 Gene

Regulatory Elements for C19orf57 Gene

Genomic Location for C19orf57 Gene

Start:
13,882,348 bp from pter
End:
13,906,452 bp from pter
Size:
24,105 bases
Orientation:
Minus strand

Genomic View for C19orf57 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for C19orf57 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C19orf57 Gene

Proteins for C19orf57 Gene

  • Protein details for C19orf57 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q0VDD7-CS057_HUMAN
    Recommended name:
    Uncharacterized protein C19orf57
    Protein Accession:
    Q0VDD7
    Secondary Accessions:
    • Q13411
    • Q8N825
    • Q96D63
    • Q9BU49

    Protein attributes for C19orf57 Gene

    Size:
    668 amino acids
    Molecular mass:
    69556 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAB02340.1; Type=Erroneous translation; Note=Wrong choice of frame.; Evidence={ECO:0000305};

    Alternative splice isoforms for C19orf57 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for C19orf57 Gene

Proteomics data for C19orf57 Gene at MOPED

Post-translational modifications for C19orf57 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C19orf57 Gene

No data available for DME Specific Peptides for C19orf57 Gene

Domains for C19orf57 Gene

Protein Domains for C19orf57 Gene

ProtoNet:

Suggested Antigen Peptide Sequences for C19orf57 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C19orf57: view

No data available for Gene Families and UniProtKB/Swiss-Prot for C19orf57 Gene

Function for C19orf57 Gene

Gene Ontology (GO) - Molecular Function for C19orf57 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
GO:0005515 protein binding IPI 16189514
genes like me logo Genes that share ontologies with C19orf57: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for C19orf57 Gene

Localization for C19orf57 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for C19orf57 Gene COMPARTMENTS Subcellular localization image for C19orf57 gene
Compartment Confidence
nucleus 3
cytosol 2
cytoskeleton 1

Gene Ontology (GO) - Cellular Components for C19orf57 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005575 cellular_component ND --
genes like me logo Genes that share ontologies with C19orf57: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for C19orf57 Gene

Pathways for C19orf57 Gene

SuperPathways for C19orf57 Gene

No Data Available

Gene Ontology (GO) - Biological Process for C19orf57 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007275 multicellular organismal development NAS 8228263
genes like me logo Genes that share ontologies with C19orf57: view

No data available for Pathways by source for C19orf57 Gene

Transcripts for C19orf57 Gene

Unigene Clusters for C19orf57 Gene

Chromosome 19 open reading frame 57:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C19orf57

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C19orf57 Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7 ^ 8 ^ 9 ^ 10
SP1: - - -
SP2: - -
SP3: -
SP4:

Relevant External Links for C19orf57 Gene

GeneLoc Exon Structure for
C19orf57
ECgene alternative splicing isoforms for
C19orf57

Expression for C19orf57 Gene

mRNA expression in normal human tissues for C19orf57 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for C19orf57 Gene

This gene is overexpressed in Testis (8.1).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for C19orf57 Gene

SOURCE GeneReport for Unigene cluster for C19orf57 Gene Hs.143288

genes like me logo Genes that share expressions with C19orf57: view

In Situ Assay Products

No data available for mRNA Expression by UniProt/SwissProt for C19orf57 Gene

Orthologs for C19orf57 Gene

This gene was present in the common ancestor of mammals.

Orthologs for C19orf57 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C19H19orf57 35
  • 99.06 (n)
  • 98.43 (a)
C19orf57 36
  • 94 (a)
OneToOne
cow
(Bos Taurus)
Mammalia C19orf57 36
  • 50 (a)
OneToOne
C7H19orf57 35
  • 70.11 (n)
  • 51.69 (a)
dog
(Canis familiaris)
Mammalia C19orf57 36
  • 55 (a)
OneToOne
C20H19orf57 35
  • 70.81 (n)
  • 52.58 (a)
mouse
(Mus musculus)
Mammalia 4930432K21Rik 35
  • 62.89 (n)
  • 46.44 (a)
4930432K21Rik 16
4930432K21Rik 36
  • 38 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia RGD1306072 35
  • 62.3 (n)
  • 45.66 (a)
Species with no ortholog for C19orf57:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C19orf57 Gene

ENSEMBL:
Gene Tree for C19orf57 (if available)
TreeFam:
Gene Tree for C19orf57 (if available)

Paralogs for C19orf57 Gene

No data available for Paralogs for C19orf57 Gene

Variants for C19orf57 Gene

Sequence variations from dbSNP and Humsavar for C19orf57 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs877701 -- 13,888,613(-) GCCCC(A/G)CCGGC intron-variant
rs1811526 -- 13,903,399(+) cgggc(A/G)cggtg intron-variant
rs2013999 -- 13,888,927(-) GGGCC(C/G)CCCAC intron-variant
rs2124912 -- 13,895,752(+) AATGC(A/G)CACCA intron-variant
rs2242130 -- 13,882,644(-) GTCCT(A/G)GCCTC utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for C19orf57 Gene

Variant ID Type Subtype PubMed ID
nsv833757 CNV Loss 17160897
nsv911098 CNV Loss 21882294
dgv3738n71 CNV Loss 21882294
nsv911102 CNV Loss 21882294
dgv3739n71 CNV Loss 21882294
nsv833760 CNV Loss 17160897
esv2668513 CNV Deletion 23128226
dgv3740n71 CNV Loss 21882294
dgv3741n71 CNV Loss 21882294

Relevant External Links for C19orf57 Gene

HapMap Linkage Disequilibrium report
C19orf57

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C19orf57 Gene

Disorders for C19orf57 Gene

Relevant External Links for C19orf57

Genetic Association Database (GAD)
C19orf57
genes like me logo Genes that share disorders with C19orf57: view

No data available for UniProtKB/Swiss-Prot for C19orf57 Gene

Publications for C19orf57 Gene

  1. Identification of human pre-T/NK cell-associated genes. (PMID: 8228263) Ranes-Goldberg M.G. … Spits H. (J. Immunol. 1993) 2 3 4
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. Towards a proteome-scale map of the human protein-protein interaction network. (PMID: 16189514) Rual J.F. … Vidal M. (Nature 2005) 3
  4. An empirical framework for binary interactome mapping. (PMID: 19060904) Venkatesan K. … Vidal M. (Nat. Methods 2009) 3
  5. Expanding the substantial interactome of NEMO using protein microarrays. (PMID: 20098747) Fenner B.J. … Prehn J.H. (PLoS ONE 2010) 3

Products for C19orf57 Gene

Sources for C19orf57 Gene

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