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Aliases for C19orf54 Gene

Aliases for C19orf54 Gene

  • Chromosome 19 Open Reading Frame 54 2 3 5

External Ids for C19orf54 Gene

Previous GeneCards Identifiers for C19orf54 Gene

  • GC19M045939
  • GC19M041246
  • GC19M037680

Summaries for C19orf54 Gene

GeneCards Summary for C19orf54 Gene

C19orf54 (Chromosome 19 Open Reading Frame 54) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C19orf54 Gene

Genomics for C19orf54 Gene

Regulatory Elements for C19orf54 Gene

Enhancers for C19orf54 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around C19orf54 on UCSC Golden Path with GeneCards custom track

Promoters for C19orf54 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around C19orf54 on UCSC Golden Path with GeneCards custom track

Genomic Location for C19orf54 Gene

Chromosome:
19
Start:
40,740,856 bp from pter
End:
40,751,553 bp from pter
Size:
10,698 bases
Orientation:
Minus strand

Genomic View for C19orf54 Gene

Genes around C19orf54 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C19orf54 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C19orf54 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C19orf54 Gene

Proteins for C19orf54 Gene

  • Protein details for C19orf54 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5BKX5-CS054_HUMAN
    Recommended name:
    UPF0692 protein C19orf54
    Protein Accession:
    Q5BKX5
    Secondary Accessions:
    • A8MSZ5
    • B4DNU7

    Protein attributes for C19orf54 Gene

    Size:
    351 amino acids
    Molecular mass:
    37779 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for C19orf54 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for C19orf54 Gene

Proteomics data for C19orf54 Gene at MOPED

Post-translational modifications for C19orf54 Gene

  • Ubiquitination at Lys 189
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for C19orf54 Gene

Domains & Families for C19orf54 Gene

Protein Domains for C19orf54 Gene

ProtoNet:

Suggested Antigen Peptide Sequences for C19orf54 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q5BKX5

UniProtKB/Swiss-Prot:

CS054_HUMAN :
  • Belongs to the UPF0692 family.
Family:
  • Belongs to the UPF0692 family.
genes like me logo Genes that share domains with C19orf54: view

No data available for Gene Families for C19orf54 Gene

Function for C19orf54 Gene

genes like me logo Genes that share phenotypes with C19orf54: view

Animal Model Products

CRISPR Products

miRNA for C19orf54 Gene

Inhibitory RNA Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C19orf54 Gene

Localization for C19orf54 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for C19orf54 Gene COMPARTMENTS Subcellular localization image for C19orf54 gene
Compartment Confidence
golgi apparatus 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C19orf54 Gene

Pathways & Interactions for C19orf54 Gene

SuperPathways for C19orf54 Gene

No Data Available

Interacting Proteins for C19orf54 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000367564%0d%0a9606.ENSP00000344818%0d%0a
Selected Interacting proteins: ENSP00000367564 for C19orf54 Gene via STRING

Symbol External ID(s) Details
UBC

Gene Ontology (GO) - Biological Process for C19orf54 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C19orf54 Gene

Drugs & Compounds for C19orf54 Gene

No Compound Related Data Available

Transcripts for C19orf54 Gene

Unigene Clusters for C19orf54 Gene

Chromosome 19 open reading frame 54:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for C19orf54 Gene

ExUns: 1a · 1b ^ 2a · 2b ^ 3 ^ 4 ^ 5a · 5b ^ 6a · 6b ^ 7a · 7b · 7c · 7d · 7e · 7f ^ 8a · 8b ^ 9
SP1: - - - - -
SP2: - - -
SP3:
SP4:
SP5: - - - -
SP6: - - -
SP7: -

Relevant External Links for C19orf54 Gene

GeneLoc Exon Structure for
C19orf54
ECgene alternative splicing isoforms for
C19orf54

Expression for C19orf54 Gene

mRNA expression in normal human tissues for C19orf54 Gene

Protein differential expression in normal tissues from HIPED for C19orf54 Gene

This gene is overexpressed in Liver, secretome (45.1) and Platelet (23.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C19orf54 Gene



SOURCE GeneReport for Unigene cluster for C19orf54 Gene Hs.585105

genes like me logo Genes that share expression patterns with C19orf54: view

Protein tissue co-expression partners for C19orf54 Gene

- Elite partner

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for C19orf54 Gene

Orthologs for C19orf54 Gene

This gene was present in the common ancestor of animals.

Orthologs for C19orf54 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia C18H19orf54 35
  • 84.48 (n)
  • 82.47 (a)
C19orf54 36
  • 83 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C1H19orf54 35
  • 85.85 (n)
  • 86.32 (a)
C19orf54 36
  • 81 (a)
OneToOne
mouse
(Mus musculus)
Mammalia BC024978 35
  • 82.56 (n)
  • 81.85 (a)
BC024978 16
BC024978 36
  • 74 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia C19H19orf54 35
  • 99.24 (n)
  • 98.29 (a)
C19orf54 36
  • 98 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia C19orf54 36
  • 60 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia C19orf54 36
  • 63 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia c19orf54 35
  • 60.23 (n)
  • 55.94 (a)
zebrafish
(Danio rerio)
Actinopterygii zgc:153119 35
  • 55.77 (n)
  • 49.43 (a)
C18H19orf54 36
  • 44 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta CG33108 36
  • 27 (a)
OneToOne
worm
(Caenorhabditis elegans)
Secernentea K07A1.3 36
  • 24 (a)
OneToOne
Species with no ortholog for C19orf54:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for C19orf54 Gene

ENSEMBL:
Gene Tree for C19orf54 (if available)
TreeFam:
Gene Tree for C19orf54 (if available)

Paralogs for C19orf54 Gene

(1) SIMAP similar genes for C19orf54 Gene using alignment to 6 proteins:

genes like me logo Genes that share paralogs with C19orf54: view

No data available for Paralogs for C19orf54 Gene

Variants for C19orf54 Gene

Sequence variations from dbSNP and Humsavar for C19orf54 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs66599479 -- 40,742,950(+) CTCCA(A/C)AGCTG intron-variant
rs66865752 -- 40,746,270(+) GCTGG(A/C)GTGCA intron-variant
rs28481926 -- 40,745,546(+) CAGGA(G/T)GGAAT intron-variant
rs28588431 -- 40,741,407(+) CACCG(C/G)ACTCC downstream-variant-500B, reference, synonymous-codon, utr-variant-3-prime
rs140185254 -- 40,744,091(+) CAGTG(A/G)CCAGG intron-variant, reference, missense

Variation tolerance for C19orf54 Gene

Residual Variation Intolerance Score: 89.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.64; 31.43% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Relevant External Links for C19orf54 Gene

Disorders for C19orf54 Gene

Relevant External Links for C19orf54

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C19orf54

No disorders were found for C19orf54 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C19orf54 Gene

Publications for C19orf54 Gene

  1. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3 67
  2. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  3. Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. (PMID: 15146197) Brandenberger R. … Stanton L.W. (Nat. Biotechnol. 2004) 3
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for C19orf54 Gene

Sources for C19orf54 Gene

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