Aliases for C19orf53 Gene
Aliases for C19orf53 Gene
External Ids for C19orf53 Gene
- HGNC: 24991
- Entrez Gene: 28974
- Ensembl: ENSG00000104979
- UniProtKB: Q9UNZ5
Previous GeneCards Identifiers for C19orf53 Gene
- GC19P013885
- GC19P013456
Summaries for C19orf53 Gene
GeneCards Summary for C19orf53 Gene
C19orf53 (Chromosome 19 Open Reading Frame 53) is a Protein Coding gene.
UniProtKB/Swiss-Prot for C19orf53 Gene
-
May have a potential role in hypercalcemia of malignancy.
No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C19orf53 Gene
Genomics for C19orf53 Gene
Regulatory Elements for C19orf53 Gene
Enhancers for C19orf53 Gene
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around C19orf53 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Location for C19orf53 Gene
- Chromosome:
- 19
- Start:
- 13,774,168 bp from pter
- End:
- 13,778,773 bp from pter
- Size:
- 4,606 bases
- Orientation:
- Plus strand
Genomic View for C19orf53 Gene
Genes around C19orf53 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 19p13.13 by Ensembl
- 19p13.13 by Entrez Gene
- 19p13.13 by HGNC
C19orf53 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for C19orf53 Gene
Proteins for C19orf53 Gene
-
Protein details for C19orf53 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9UNZ5-L10K_HUMAN
- Recommended name:
- Leydig cell tumor 10 kDa protein homolog
- Protein Accession:
- Q9UNZ5
- B2R4J9
Protein attributes for C19orf53 Gene
- Size:
- 99 amino acids
- Molecular mass:
- 10577 Da
- Quaternary structure:
- No Data Available
Protein Expression for C19orf53 Gene
Post-translational modifications for C19orf53 Gene
Other Protein References for C19orf53 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for C19orf53
- Novus Biologicals Antibodies for C19orf53
-
Abcam antibodies for C19orf53
- Invitrogen Antibodies for C19orf53
- Search GeneTex for Antibodies for C19orf53
-
Santa Cruz Biotechnology (SCBT) Antibodies for C19orf53
Protein Products
-
OriGene Purified Proteins for C19orf53
- Search Origene for MassSpec and Protein Over-expression Lysates for C19orf53
- Origene Custom Protein Services for C19orf53
- antibodies-online Proteins for C19orf53: See all 3
- Search antibodies-online for peptides
- Search GeneTex for Proteins for C19orf53
Assay Products
No data available for DME Specific Peptides for C19orf53 Gene
Domains & Families for C19orf53 Gene
Suggested Antigen Peptide Sequences for C19orf53 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q9UNZ5- Family:
-
- Belongs to the UPF0390 family.
No data available for Gene Families for C19orf53 Gene
Function for C19orf53 Gene
Molecular function for C19orf53 Gene
- UniProtKB/Swiss-Prot Function:
- May have a potential role in hypercalcemia of malignancy.
Phenotypes for C19orf53 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for C19orf53
-
-
ViGene Biosciences lentiviral particle packaged cDNA for C19orf53 gene
- Search ViGene Biosciences for C19orf53
CRISPR Products
-
OriGene CRISPR knockouts for C19orf53
-
Santa Cruz Biotechnology (SCBT) CRISPR for C19orf53
- GenScript: Design CRISPR guide RNA sequences for C19orf53
miRNA for C19orf53 Gene
- miRTarBase miRNAs that target C19orf53
-
- hsa-mir-98-5p (MIRT027806)
- hsa-mir-6728-5p (MIRT451134)
- hsa-mir-6878-3p (MIRT451135)
- hsa-mir-4278 (MIRT451136)
- hsa-mir-4769-5p (MIRT451137)
- hsa-mir-4654 (MIRT451138)
- hsa-mir-6766-5p (MIRT451139)
- hsa-mir-6756-5p (MIRT451140)
- hsa-mir-608 (MIRT451141)
- hsa-mir-4651 (MIRT451142)
- hsa-mir-7110-5p (MIRT451143)
- hsa-mir-6842-5p (MIRT451144)
- hsa-mir-6752-5p (MIRT451145)
- hsa-mir-5187-5p (MIRT451146)
- hsa-mir-6735-3p (MIRT451147)
- hsa-mir-6851-5p (MIRT451148)
- hsa-mir-3689d (MIRT451149)
- hsa-mir-4500 (MIRT451150)
- hsa-mir-4458 (MIRT451151)
- hsa-let-7i-5p (MIRT451152)
- hsa-let-7g-5p (MIRT451153)
- hsa-let-7f-5p (MIRT451154)
- hsa-let-7e-5p (MIRT451155)
- hsa-let-7d-5p (MIRT451156)
- hsa-let-7c-5p (MIRT451157)
- hsa-let-7b-5p (MIRT451158)
- hsa-let-7a-5p (MIRT451159)
- hsa-mir-4781-3p (MIRT451160)
- hsa-mir-6514-5p (MIRT451161)
- hsa-mir-4802-5p (MIRT451162)
- hsa-mir-8076 (MIRT451163)
- hsa-mir-6732-5p (MIRT451164)
- hsa-mir-6805-5p (MIRT451165)
- hsa-mir-6794-5p (MIRT451166)
- hsa-mir-4716-3p (MIRT451167)
miRNA Products
- Search ViGene Biosciences for C19orf53
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for C19orf53
- Browse OriGene Inhibitory RNA Products For C19orf53
- Search ViGene Biosciences for C19orf53
Clone Products
-
OriGene ORF clones in human for C19orf53
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- VectorBuilder custom plasmid, inducible vectors for C19orf53
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for C19orf53
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
ViGene Biosciences adenoviral particle packaged cDNA for C19orf53 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for C19orf53 gene
- Search ViGene Biosciences for C19orf53
Flow Cytometry Products
No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C19orf53 Gene
Localization for C19orf53 Gene
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IDA | -- |
| GO:0005730 | nucleolus | IDA | -- |
No data available for Subcellular locations from UniProtKB/Swiss-Prot for C19orf53 Gene
Pathways & Interactions for C19orf53 Gene
No Data Available
No data available for Pathways by source and SIGNOR curated interactions for C19orf53 Gene
Transcripts for C19orf53 Gene
mRNA/cDNA for C19orf53 Gene
- (1) REFSEQ mRNAs :
- (4) Additional mRNA sequences :
- (318) Selected AceView cDNA sequences:
- (6) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for C19orf53 Gene
CRISPR Products
-
OriGene CRISPR knockouts for C19orf53
-
Santa Cruz Biotechnology (SCBT) CRISPR for C19orf53
- GenScript: Design CRISPR guide RNA sequences for C19orf53
miRNA Products
- Search ViGene Biosciences for C19orf53
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for C19orf53
- Browse OriGene Inhibitory RNA Products For C19orf53
- Search ViGene Biosciences for C19orf53
Clone Products
-
OriGene ORF clones in human for C19orf53
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for C19orf53
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for C19orf53
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
Expression for C19orf53 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Brain (Nervous System)
- Bone (Muscoskeletal System)
-
Uterus (Reproductive System)
-
Prostate (Endocrine System)
-
Spleen (Hematopoietic System)
-
Thyroid (Endocrine System)
-
Gall Bladder (Hepatobiliary System)
-
Kidney (Urinary System)
-
Adrenal Gland (Endocrine System)
-
Esophagus (Gastrointestinal Tract)
-
Ovary (Reproductive System)
-
Adipose (Muscoskeletal System)
This gene is overexpressed in Peripheral blood mononuclear cells (51.7).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for C19orf53 Gene
NURSA nuclear receptor signaling pathways regulating expression of C19orf53 Gene:
C19orf53SOURCE GeneReport for Unigene cluster for C19orf53 Gene:
Hs.231616Evidence on tissue expression from TISSUES for C19orf53 Gene
- Blood(4.2)
- Intestine(2.5)
- Nervous system(2)
Primer Products
-
OriGene qPCR primer pairs and template standards for C19orf53
-
OriGene qPCR primer pairs for C19orf53
No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for C19orf53 Gene
Orthologs for C19orf53 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | C19orf53 35 |
|
OneToOne | |
| C19H19orf53 34 |
|
||||
| dog (Canis familiaris) |
Mammalia | C20H19orf53 34 |
|
||
| C19orf53 35 |
|
OneToOne | |||
| cow (Bos Taurus) |
Mammalia | C7H19orf53 34 35 35 |
|
||
| mouse (Mus musculus) |
Mammalia | D8Ertd738e 34 16 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | LOC288913 34 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | C19orf53 35 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | C19orf53 35 |
|
OneToOne | |
| zebrafish (Danio rerio) |
Actinopterygii | C1H19orf53 35 |
|
OneToOne |
- Species where no ortholog for C19orf53 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for C19orf53 Gene
Pseudogenes.org Pseudogenes for C19orf53 Gene
No data available for Paralogs for C19orf53 Gene
Variants for C19orf53 Gene
| SNP ID | Clin | Chr 19 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000400241 | -- | 13,774,793(+) | TGGAG(C/T)CCGGG | intron-variant | |
| rs1000524220 | -- | 13,779,174(+) | GGTCC(C/T)GCATA | downstream-variant-500B | |
| rs1000765052 | -- | 13,776,696(+) | TCCCA(A/G)TAATA | intron-variant | |
| rs1000771175 | -- | 13,774,561(+) | CGGGG(C/T)CCAAG | downstream-variant-500B, reference, synonymous-codon | |
| rs1001762923 | -- | 13,775,258(+) | GGGCT(C/T)AAAGA | intron-variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv3893166 | CNV | gain | 25118596 |
| nsv833757 | CNV | loss | 17160897 |
Residual Variation Intolerance Score:
88.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
12.11;
93.84% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for C19orf53 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- C19orf53
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C19orf53 Gene
Disorders for C19orf53 Gene
Relevant External Links for C19orf53
No disorders were found for C19orf53 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C19orf53 Gene
Publications for C19orf53 Gene
- Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PMID: 11042152) Zhang Q.-H. … Chen Z. (Genome Res. 2000) 2 3 4 64
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
- Panorama of ancient metazoan macromolecular complexes. (PMID: 26344197) Wan C. … Emili A. (Nature 2015) 3 64
- A human interactome in three quantitative dimensions organized by stoichiometries and abundances. (PMID: 26496610) Hein M.Y. … Mann M. (Cell 2015) 3 64
- The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis. (PMID: 26687479) Oliviero G. … Cagney G. (Sci. Rep. 2015) 3 64
Products for C19orf53 Gene
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- Custom Antibody ServicesOriGene Antibodies for C19orf53
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for C19orf53
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- OriGene qPCR primer pairs and template standards for C19orf53
- OriGene qPCR primer pairs for C19orf53
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- GenScript: Design CRISPR guide RNA sequences for C19orf53
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- Novus Biologicals Antibodies for C19orf53
- Novus Biologicals proteins and lysates for C19orf53
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- ViGene Biosciences adenoviral particle packaged cDNA for C19orf53 gene
- ViGene Biosciences lentiviral particle packaged cDNA for C19orf53 gene
- Search ViGene Biosciences for C19orf53
- Santa Cruz Biotechnology (SCBT) Antibodies for C19orf53
- Search Santa Cruz Biotechnology (SCBT) for C19orf53 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for C19orf53
- Cyagen custom Knockout/knockin (KOKI) mouse models for C19orf53
- VectorBuilder custom plasmid, inducible vectors for C19orf53
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for C19orf53
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for C19orf53 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer