Aliases for C19orf48 Gene
Aliases for C19orf48 Gene
External Ids for C19orf48 Gene
- HGNC: 29667
- Entrez Gene: 84798
- Ensembl: ENSG00000167747
- UniProtKB: Q6RUI8
Previous GeneCards Identifiers for C19orf48 Gene
- GC19M055993
- GC19M051300
- GC19M047635
Summaries for C19orf48 Gene
GeneCards Summary for C19orf48 Gene
C19orf48 (Chromosome 19 Open Reading Frame 48) is a Protein Coding gene. Diseases associated with C19orf48 include Intraocular Lymphoma and Eye Lymphoma.
No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C19orf48 Gene
Genomics for C19orf48 Gene
Regulatory Elements for C19orf48 Gene
Enhancers for C19orf48 Gene
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around C19orf48 on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the C19orf48 gene promoter:
Regulatory Element Products
Genomic Location for C19orf48 Gene
- Chromosome:
- 19
- Start:
- 50,797,693 bp from pter
- End:
- 50,804,929 bp from pter
- Size:
- 7,237 bases
- Orientation:
- Minus strand
Genomic View for C19orf48 Gene
Genes around C19orf48 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 19q13.33 by Ensembl
- 19q13.33 by Entrez Gene
- 19q13.33 by HGNC
C19orf48 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for C19orf48 Gene
Proteins for C19orf48 Gene
-
Protein details for C19orf48 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q6RUI8-CS048_HUMAN
- Recommended name:
- Uncharacterized protein C19orf48
- Protein Accession:
- Q6RUI8
Protein attributes for C19orf48 Gene
- Size:
- 117 amino acids
- Molecular mass:
- 13085 Da
- Quaternary structure:
- No Data Available
Protein Expression for C19orf48 Gene
Post-translational modifications for C19orf48 Gene
Other Protein References for C19orf48 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for C19orf48
-
Abcam antibodies for C19orf48
- Invitrogen Antibodies for C19orf48
- Search GeneTex for Antibodies for C19orf48
Protein Products
-
OriGene Purified Proteins for C19orf48
- Search Origene for MassSpec and Protein Over-expression Lysates for C19orf48
- Origene Custom Protein Services for C19orf48
- Search GeneTex for Proteins for C19orf48
Assay Products
No data available for DME Specific Peptides for C19orf48 Gene
Domains & Families for C19orf48 Gene
Gene Families for C19orf48 Gene
Protein Domains for C19orf48 Gene
- ProtoNet:
Suggested Antigen Peptide Sequences for C19orf48 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
No data available for UniProtKB/Swiss-Prot for C19orf48 Gene
Function for C19orf48 Gene
Phenotypes for C19orf48 Gene
- GenomeRNAi human phenotypes for C19orf48:
Animal Model Products
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-
-
ViGene Biosciences lentiviral particle packaged cDNA for C19orf48 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for C19orf48 gene
- Search ViGene Biosciences for C19orf48
CRISPR Products
-
OriGene CRISPR knockouts for C19orf48
-
Santa Cruz Biotechnology (SCBT) CRISPR for C19orf48
- GenScript: Design CRISPR guide RNA sequences for C19orf48
miRNA for C19orf48 Gene
- miRTarBase miRNAs that target C19orf48
miRNA Products
- Search ViGene Biosciences for C19orf48
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for C19orf48
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-
ViGene Biosciences ready-to-package AAV shRNAs for C19orf48 gene
Clone Products
- Sino Biological Human cDNA Clone for C19orf48
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- Addgene plasmids for C19orf48
- VectorBuilder custom plasmid, inducible vectors for C19orf48
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for C19orf48
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for C19orf48
-
ViGene Biosciences adenoviral particle packaged cDNA for C19orf48 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for C19orf48 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for C19orf48 gene
Flow Cytometry Products
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C19orf48 Gene
Localization for C19orf48 Gene
| Compartment | Confidence |
|---|---|
| extracellular | 3 |
| plasma membrane | 1 |
| nucleus | 1 |
| cytosol | 1 |
| golgi apparatus | 1 |
No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C19orf48 Gene
Pathways & Interactions for C19orf48 Gene
No Data Available
Interacting Proteins for C19orf48 Gene
| Symbol | External ID(s) | Details |
|---|---|---|
| ILF3 |
No data available for Pathways by source and SIGNOR curated interactions for C19orf48 Gene
Transcripts for C19orf48 Gene
mRNA/cDNA for C19orf48 Gene
- (10) REFSEQ mRNAs :
- (4) Additional mRNA sequences :
- (569) Selected AceView cDNA sequences:
- (14) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for C19orf48 Gene
CRISPR Products
-
OriGene CRISPR knockouts for C19orf48
-
Santa Cruz Biotechnology (SCBT) CRISPR for C19orf48
- GenScript: Design CRISPR guide RNA sequences for C19orf48
miRNA Products
- Search ViGene Biosciences for C19orf48
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for C19orf48
- Browse OriGene Inhibitory RNA Products For C19orf48
-
ViGene Biosciences ready-to-package AAV shRNAs for C19orf48 gene
Clone Products
- Sino Biological Human cDNA Clone for C19orf48
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Addgene plasmids for C19orf48
- VectorBuilder custom plasmid, inducible vectors for C19orf48
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for C19orf48
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | ^ | 5 | ^ | 6 | ^ | 7a | · | 7b | · | 7c | ^ | 8a | · | 8b | · | 8c | · | 8d | · | 8e | · | 8f | · | 8g | · | 8h | · | 8i | · | 8j | · | 8k |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||
| SP2: | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||
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| SP4: | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||
| SP5: | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||
| SP6: | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||
| SP7: | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||
| SP8: | - | - | |||||||||||||||||||||||||||||||||||||||||||
| SP9: | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||
| SP10: | - | - | - | ||||||||||||||||||||||||||||||||||||||||||
| SP11: | - | - | - | ||||||||||||||||||||||||||||||||||||||||||
| SP12: | - | - | - | - |
Expression for C19orf48 Gene
mRNA differential expression in normal tissues according to GTEx for C19orf48 Gene
This gene is overexpressed in Pancreas (x5.1) and Prostate (x4.4).
This gene is overexpressed in Breast (69.0).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C19orf48 Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of C19orf48 Gene:
C19orf48SOURCE GeneReport for Unigene cluster for C19orf48 Gene:
Hs.256301Evidence on tissue expression from TISSUES for C19orf48 Gene
- Nervous system(3.2)
- Lung(2.8)
- Eye(2.4)
- Intestine(2.4)
Primer Products
-
OriGene qPCR primer pairs and template standards for C19orf48
-
OriGene qPCR primer pairs for C19orf48
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for C19orf48 Gene
Orthologs for C19orf48 Gene
This gene was present in the common ancestor of human and chimp.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | C19H19orf48 34 |
|
||
| C19orf48 35 |
|
OneToOne |
- Species where no ortholog for C19orf48 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- cow (Bos Taurus)
- dog (Canis familiaris)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- lizard (Anolis carolinensis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- mouse (Mus musculus)
- oppossum (Monodelphis domestica)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rainbow trout (Oncorhynchus mykiss)
- rat (Rattus norvegicus)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
- zebrafish (Danio rerio)
Paralogs for C19orf48 Gene
No data available for Paralogs for C19orf48 Gene
Variants for C19orf48 Gene
| SNP ID | Clin | Chr 19 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000202670 | -- | 50,803,817(+) | CTCCT(C/T)GGCAG | intron-variant, upstream-variant-2KB, utr-variant-5-prime | |
| rs1000507527 | -- | 50,800,465(+) | CGGCC(A/G)GGCAT | intron-variant, upstream-variant-2KB | |
| rs1000823791 | -- | 50,800,676(+) | CGTGA(A/C)CCTGG | intron-variant, upstream-variant-2KB | |
| rs1001069952 | -- | 50,804,600(+) | GGGCG(C/G)GGGTT | upstream-variant-2KB, utr-variant-5-prime | |
| rs1001834226 | -- | 50,801,528(+) | TGAAG(A/T)GCAAT | intron-variant, upstream-variant-2KB |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv203n21 | CNV | loss | 19592680 |
| nsv1140251 | OTHER | inversion | 24896259 |
Residual Variation Intolerance Score:
87.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
6.47;
77.47% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for C19orf48 Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C19orf48 Gene
Disorders for C19orf48 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| intraocular lymphoma |
|
|
| eye lymphoma |
|
|
Search C19orf48 in MalaCards
View complete list of genes associated with diseases
Relevant External Links for C19orf48
- Atlas of Genetics and Cytogenetics in Oncology and Haematology:
- C19orf48
No data available for UniProtKB/Swiss-Prot and Genatlas for C19orf48 Gene
Publications for C19orf48 Gene
- C19orf48 encodes a minor histocompatibility antigen recognized by CD8+ cytotoxic T cells from renal cell carcinoma patients. (PMID: 18698046) Tykodi S.S. … Warren E.H. (Clin. Cancer Res. 2008) 2 3 64
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
- [Cloning and sequence analysis of a new, full-length cDNA fragment of drug resistance-related gene in human lung adenocarcinoma]. (PMID: 12452007) Zhou X.D. … Chen J. (Ai Zheng 2002) 2 3 64
- Translation of 5' leaders is pervasive in genes resistant to eIF2 repression. (PMID: 25621764) Andreev D.E. … Baranov P.V. (Elife 2015) 3 64
- The human lung cancer drug resistance-related gene BC006151 regulates chemosensitivity in H446/CDDP cells. (PMID: 20686220) Li S. … Qian G. (Biol. Pharm. Bull. 2010) 3 64
Products for C19orf48 Gene
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- Novus Biologicals Antibodies for C19orf48
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- Search GeneTex for Antibodies for C19orf48
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- ViGene Biosciences adenoviral particle packaged cDNA for C19orf48 gene
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- Search ViGene Biosciences for C19orf48
- Horizon Cell Lines for C19orf48
- Cyagen custom Knockout/knockin (KOKI) mouse models for C19orf48
- VectorBuilder custom plasmid, inducible vectors for C19orf48
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for C19orf48
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for C19orf48 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
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- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer