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Aliases for C19orf48 Gene

Aliases for C19orf48 Gene

  • Chromosome 19 Open Reading Frame 48 2 3
  • Multidrug Resistance-Related Protein 2 4

External Ids for C19orf48 Gene

Summaries for C19orf48 Gene

GeneCards Summary for C19orf48 Gene

C19orf48 (Chromosome 19 Open Reading Frame 48) is a Protein Coding gene. Diseases associated with C19orf48 include intraocular lymphoma and temporal lobe epilepsy.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C19orf48 Gene

Genomics for C19orf48 Gene

Genomic Location for C19orf48 Gene

Start:
50,797,704 bp from pter
End:
50,804,929 bp from pter
Size:
7,226 bases
Orientation:
Minus strand

Genomic View for C19orf48 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for C19orf48 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C19orf48 Gene

Regulatory Elements for C19orf48 Gene

Proteins for C19orf48 Gene

  • Protein details for C19orf48 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6RUI8-CS048_HUMAN
    Recommended name:
    Uncharacterized protein C19orf48
    Protein Accession:
    Q6RUI8
    Secondary Accessions:

    Protein attributes for C19orf48 Gene

    Size:
    117 amino acids
    Molecular mass:
    13085 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C19orf48 Gene

Proteomics data for C19orf48 Gene at MOPED

Post-translational modifications for C19orf48 Gene

No Post-translational modifications

No data available for DME Specific Peptides for C19orf48 Gene

Domains for C19orf48 Gene

Protein Domains for C19orf48 Gene

ProtoNet:
genes like me logo Genes that share domains with C19orf48: view

No data available for Gene Families and UniProtKB/Swiss-Prot for C19orf48 Gene

Function for C19orf48 Gene

miRNA for C19orf48 Gene

miRTarBase miRNAs that target C19orf48

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for C19orf48 Gene

Localization for C19orf48 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for C19orf48 Gene COMPARTMENTS Subcellular localization image for C19orf48 gene
Compartment Confidence
extracellular 3
golgi apparatus 2
cytosol 1
nucleus 1
plasma membrane 1
vacuole 1

No data available for Gene Ontology (GO) - Cellular Components for C19orf48 Gene

Pathways for C19orf48 Gene

SuperPathways for C19orf48 Gene

No Data Available

Interacting Proteins for C19orf48 Gene

Gene Ontology (GO) - Biological Process for C19orf48 Gene

None

No data available for Pathways by source for C19orf48 Gene

Compounds for C19orf48 Gene

(8) Novoseek inferred chemical compound relationships for C19orf48 Gene

Compound -log(P) Hits PubMed IDs
probenecid 63.2 3
daunorubicin 62.4 2
doxorubicin 56.3 1
estrone sulfate 48.9 1
verapamil 37.7 1
genes like me logo Genes that share compounds with C19orf48: view

Transcripts for C19orf48 Gene

Unigene Clusters for C19orf48 Gene

Chromosome 19 open reading frame 48:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for C19orf48 Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7a · 7b · 7c ^ 8a · 8b · 8c · 8d · 8e · 8f · 8g · 8h · 8i · 8j · 8k
SP1: - - - - - -
SP2: - - - -
SP3: - -
SP4: - - - - - - -
SP5: - - - - - - - -
SP6: - - - - - -
SP7: - - - -
SP8: - -
SP9: - - - - -
SP10: - - -
SP11: - - -
SP12: - - - -

Relevant External Links for C19orf48 Gene

GeneLoc Exon Structure for
C19orf48
ECgene alternative splicing isoforms for
C19orf48

Expression for C19orf48 Gene

mRNA expression in normal human tissues for C19orf48 Gene

mRNA differential expression in normal tissues according to GTEx for C19orf48 Gene

This gene is overexpressed in Pancreas (5.1) and Prostate (4.4).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for C19orf48 Gene

SOURCE GeneReport for Unigene cluster for C19orf48 Gene Hs.256301

genes like me logo Genes that share expressions with C19orf48: view

Orthologs for C19orf48 Gene

This gene was present in the common ancestor of human and mouse.

Orthologs for C19orf48 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C19H19orf48 36
  • 98.29 (n)
  • 95.73 (a)
C19orf48 37
  • 96 (a)
OneToOne
mouse
(Mus musculus)
Mammalia 2410002F23Rik 16
Species with no ortholog for C19orf48:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C19orf48 Gene

ENSEMBL:
Gene Tree for C19orf48 (if available)
TreeFam:
Gene Tree for C19orf48 (if available)

Paralogs for C19orf48 Gene

No data available for Paralogs for C19orf48 Gene

Variants for C19orf48 Gene

Sequence variations from dbSNP and Humsavar for C19orf48 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs9991 -- 50,797,973(-) GGTAC(C/T)GGAAG utr-variant-3-prime
rs266119 -- 50,797,279(-) TTGCT(G/T)TGTGT intron-variant
rs788891 -- 50,806,607(-) cttgt(A/C)gtctt upstream-variant-2KB
rs2247216 -- 50,804,576(-) AAATG(A/C/T)TGGGG utr-variant-5-prime, upstream-variant-2KB
rs2247289 -- 50,804,835(-) GCAGG(G/T)GACAA utr-variant-5-prime, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for C19orf48 Gene

Variant ID Type Subtype PubMed ID
dgv3977n71 CNV Loss 21882294
dgv203n21 CNV Loss 19592680

Relevant External Links for C19orf48 Gene

HapMap Linkage Disequilibrium report
C19orf48
Human Gene Mutation Database (HGMD)
C19orf48

Disorders for C19orf48 Gene

(7) Novoseek inferred disease relationships for C19orf48 Gene

Disease -log(P) Hits PubMed IDs
leukemia 25.5 2
breast cancer 17.7 6
cancer 16.9 2
acute leukemia 14.1 2
tumors 11 4
genes like me logo Genes that share disorders with C19orf48: view

No data available for UniProtKB/Swiss-Prot for C19orf48 Gene

Publications for C19orf48 Gene

  1. [Cloning and sequence analysis of a new, full-length cDNA fragment of drug resistance-related gene in human lung adenocarcinoma]. (PMID: 12452007) Zhou X.D. … Chen J. (Ai Zheng 2002) 2 3
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. C19orf48 encodes a minor histocompatibility antigen recognized by CD8+ cytotoxic T cells from renal cell carcinoma patients. (PMID: 18698046) Tykodi S.S. … Warren E.H. (Clin. Cancer Res. 2008) 2 3
  4. The human lung cancer drug resistance-related gene BC006151 regulates chemosensitivity in H446/CDDP cells. (PMID: 20686220) Li S. … Qian G. (Biol. Pharm. Bull. 2010) 3
  5. Translation of 5' leaders is pervasive in genes resistant to eIF2 repression. (PMID: 25621764) Andreev D.E. … Baranov P.V. (Elife 2015) 3

Products for C19orf48 Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate C19orf48
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat
  • Predesigned siRNA for gene silencing in human,mouse,rat for C19orf48
  • Block miRNA regulation of C19orf48 using miScript Target Protectors

Sources for C19orf48 Gene

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