C19orf47 Gene
protein-coding GIFtS: 41
GCID: GC19M040826
|
|
Chromosome 19 Open Reading Frame 47
| |
Aliases
for C19orf47 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
10fRNAdb,
12H-InvDB,
13NCBI,
14NONCODE,
and/or 15RNAdb)
About This Section
|
| Aliases |
|---|
| Chromosome 19 Open Reading Frame 471 2 | | Uncharacterized Protein C19orf472 |
Export aliases for C19orf47 gene to outside databasesPrevious GC identifers: GC19M045517 GC19M037262 |
Summaries
for C19orf47 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
GeneCards Summary for C19orf47 Gene: 
C19orf47 (chromosome 19 open reading frame 47) is a protein-coding gene.
|
Genomic Views
for C19orf47 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 73),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000019.9 NT_011109.16 NC_018930.2
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the C19orf47 gene promoter:
Max1 Pax-5 AREB6 CP2 CBF-A CBF-B CP1A c-Myc CBF(2)
Other transcription factors
Search SABiosciences Chromatin IP Primers for C19orf47
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C19orf47 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 19q13.2 Ensembl cytogenetic band: 19q13.2 HGNC cytogenetic band: 19q13.2C19orf47 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19M040826: view genomic region
(about GC identifiers)
Start:
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40,825,443 bp from pter |
End:
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40,854,434 bp from pter |
Size:
|
28,992 bases |
Orientation:
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minus strand |
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Proteins
for C19orf47 gene
(According to
UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE 1MOPED,
2PaxDb, and 3MAXQB
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Cloud-Clone Corp.,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Cloud-Clone Corp.,
Ontologies according to Gene
Ontology Consortium 01 Oct 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
LSBio,
Abcam, and/or
Cloud-Clone Corp.)
About This Section
|
UniProtKB/Swiss-Prot: CS047_HUMAN, Q8N9M1 (See
protein sequence)Recommended Name: Uncharacterized protein C19orf47 Size: 422 amino acids; 44746 Da
Secondary accessions: Q8IZ33 Q8N0V9Alternative splicing: 3 isoforms: Q8N9M1-1 Q8N9M1-2 Q8N9M1-3 Explore the universe of human proteins at neXtProt for C19orf47: NX_Q8N9M1
Explore proteomics data for C19orf47 at MOPED
Post-translational modifications:
View modification sites using PhosphoSitePlusView neXtProt modification sites for NX_Q8N9M1
C19orf47 Protein expression data from MOPED1, PaxDb2 and
MAXQB3 : About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001243369.1 NP_001243370.1
ENSEMBL proteins: ENSP00000463159 ENSP00000464567 ENSP00000375889 ENSP00000350556 ENSP00000463305 ENSP00000464478 ENSP00000463294
Human Recombinant Protein Products for C19orf47:
C19orf47 Antibody Products:
Assay Products for C19orf47: |
Protein
Domains /
Families
for C19orf47 gene(According to HGNC, IUPHAR, InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| 1 InterPro protein domain:Graphical View of Domain Structure for InterPro Entry Q8N9M1 ProtoNet protein and cluster: Q8N9M1
C19orf47 for domains About GeneDecksing
|
Function
for C19orf47 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Oct 2013 via
Entrez Gene.)
About This Section
|
Animal Models:
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C19orf47 |
|
Pathways & Interactions
for C19orf47 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Sino Biological,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Oct 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for C19orf47
STRING Interaction
Network Preview (showing 1 interactants - click image to see more details)
1 Interacting protein for C19orf47 (ENSP000003758894) via UniProtKB, MINT, STRING, and/or I2DAbout this table
|
Drugs & Compounds
for C19orf47 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
IUPHAR,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for C19orf47 (CS047)
Search CenterWatch for drugs/clinical trials and news about C19orf47 / CS047
|
Transcripts
for C19orf47 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
Conferences by KenesGroup,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for C19orf47 gene (3 alternative transcripts): NM_178830.2 NM_001256440.1 NM_001256441.1 Unigene Cluster for C19orf47: Chromosome 19 open reading frame 47 Hs.631557 [show with all ESTs]Unigene Representative Sequence: CR9367609 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000582783(uc002oni.4) ENST00000577617 ENST00000392035(uc002ong.3 uc002onh.3)
ENST00000582734 ENST00000584868 ENST00000357884 ENST00000582006 ENST00000580606
ENST00000580977
Primer
Products: |  | OriGene qPCR primer pairs and template standards for C19orf47
OriGene qSTAR qPCR primer pairs in human, mouse for C19orf47
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat C19orf47 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C19orf47 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C19orf47 |
Additional mRNA sequence: AK094207.1 AL834131.1 BC023623.2 BC027935.1 CR936760.1 NR_046202.1 10 DOTS entries: DT.308784 DT.100783728 DT.121470397 DT.95070273 DT.100783729 DT.100783731 DT.121470336 DT.100707851 DT.100885917 DT.91781047 24/94 AceView cDNA sequences (see all 94): BI827924 BE393376 AL834131 BE395946 BI259748 BM459040 BQ064955 BC027935 F36994 BX363522 BQ685500 AK094207 BQ686373 BC023623 BM763065 BU857685 NM_178830 AL555423 BM670612 BI256930 BQ879861 BG680008 BU188266 CR591102
GeneLoc Exon Structure
5/6 Alternative Splicing Database (ASD) splice patterns (SP) for C19orf47 (see all 6) About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12a | · | 12b | · | 12c | ^ | 13a | · | 13b |
|---|
|
| SP1: | | | - | | - | | | | - | | | | | | | | - | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | - | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | - | | | | | | | | - | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for C19orf47
|
Expression
for C19orf47 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| C19orf47 expression in normal human tissues
(normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: TCCTCTGTGC
About this image
See C19orf47 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for C19orf47
SOURCE GeneReport for Unigene cluster: Hs.631557
SABiosciences Custom PCR Arrays for C19orf47
Primer
Products: | | OriGene qPCR primer pairs and template standards for C19orf47
OriGene qSTAR qPCR primer pairs in human, mouse for C19orf47
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat C19orf47 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C19orf47 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C19orf47 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C19orf47 |
Orthologs
for C19orf47 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for C19orf47 gene from 5/13 species (see all 13) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
lizard
(Anolis carolinensis) |
Reptilia |
C19ORF476 |
Uncharacterized protein |
62(a) |
1 ↔ 1 |
LGf(2268935-2277057) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.67392 |
Xenopus laevis transcribed sequence with weak similarity more |
75.82(n) |
|
BX854187.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
C18H19orf476 |
chromosome 19 open reading frame 47 |
50(a) |
1 ↔ 1 |
18(35122766-35139877) |
fruit fly
(Drosophila melanogaster) |
Insecta |
CG168126 |
-- |
19(a) |
1 ↔ 1 |
2L(13222561-13224550) |
worm
(Caenorhabditis elegans) |
Secernentea |
F53F8.56 |
Protein F53F8.5 |
20(a) |
1 ↔ 1 |
V(20700559-20704037) |
Species with no ortholog for C19orf47
ENSEMBL Gene Tree for C19orf47 (if available)
TreeFam Gene Tree for C19orf47 (if available) |
Paralogs
for C19orf47 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for C19orf47 gene
18/36 SIMAP similar genes for C19orf47 using alignment to 6 protein entries: CS047_HUMAN (see all proteins)
(see all similar genes):MTX2 COX7A2 C12orf23 ZNF738 SENP7 SUN3
WDR6 PSD3 TGFBR3 IPO7 MST132 C15orf40
ZNF415 ZNF616 CNOT2 FANCA KLHDC1 LRTOMT
C19orf47 for paralogs About GeneDecksing
|
Genomic Variants
for C19orf47 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
4UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 19 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for C19orf47 (40825443 - 40854434 bp)
Structural Variations
Database of Genomic Variants (DGV) 3 variations for C19orf47: About this table
| | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing C19orf47 |
|
Disorders
/ Diseases
for C19orf47 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Conferences by KenesGroup,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for C19orf47 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for C19orf47 gene, integrated from 9 sources (see all 11):
(articles sorted by number of sources associating them with C19orf47) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
- Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)2 Mayya V.... Han D.K. (2009)
- Two-hybrid analysis identifies PSMD11, a non-ATPase s ubunit of the proteasome, as a novel interaction partner of AMP-activated prote in kinase. (PubMed id 19616115)1 Moreno D....Sanz P. (2009)
- A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)2 Dephoure N.... Gygi S.P. (2008)
- The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
- The LIFEdb database in 2006. (PubMed id 16381901)1 Mehrle A....Wiemann S. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- From ORFeome to biology: a functional genomics pipeline. (PubMed id 15489336)1 Wiemann S....Poustka A. (2004)
- Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1 Wiemann S.... Poustka A. (2001)
|
External Searches for C19orf47 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing C19orf47 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing C19orf47 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing C19orf47 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for C19orf47 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for C19orf47 gene:
Search GeneIP for patents involving C19orf47
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for C19orf47 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
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 |
 |
|  | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat C19orf47 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing C19orf47 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C19orf47 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat C19orf47 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C19orf47 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C19orf47 |
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 |
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 | | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C19orf47 |
|  |  |  |  | | | | Search ThermoFisher Antibodies for C19orf47 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C19orf47 |
| |  |  | | | | LSBio Antibodies in human, mouse, rat for C19orf47 |
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