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Aliases for C19orf44 Gene

Aliases for C19orf44 Gene

  • Chromosome 19 Open Reading Frame 44 2 3 5

External Ids for C19orf44 Gene

Previous GeneCards Identifiers for C19orf44 Gene

  • GC19P016469
  • GC19P016607
  • GC19P016175
  • GC19P016578
  • GC19P016816
  • GC19P017593
  • GC19P018261
  • GC19P018663

Summaries for C19orf44 Gene

GeneCards Summary for C19orf44 Gene

C19orf44 (Chromosome 19 Open Reading Frame 44) is a Protein Coding gene.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C19orf44 Gene

Genomics for C19orf44 Gene

Regulatory Elements for C19orf44 Gene


Enhancers around C19orf44 on UCSC Golden Path with GeneCards custom track

Promoters for C19orf44 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000107764 -10 1400 HDGF PKNOX1 CREB3L1 ARNT ARID4B SIN3A DMAP1 ZNF2 YY1 ZNF766

Genomic Location for C19orf44 Gene

Chromosome:
19
Start:
16,496,311 bp from pter
End:
16,521,369 bp from pter
Size:
25,059 bases
Orientation:
Plus strand

Genomic View for C19orf44 Gene

Genes around C19orf44 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C19orf44 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C19orf44 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C19orf44 Gene

Proteins for C19orf44 Gene

  • Protein details for C19orf44 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9H6X5-CS044_HUMAN
    Recommended name:
    Uncharacterized protein C19orf44
    Protein Accession:
    Q9H6X5
    Secondary Accessions:
    • Q8N6Y7

    Protein attributes for C19orf44 Gene

    Size:
    657 amino acids
    Molecular mass:
    71343 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for C19orf44 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for C19orf44 Gene

Post-translational modifications for C19orf44 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for C19orf44 Gene

Domains & Families for C19orf44 Gene

Protein Domains for C19orf44 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C19orf44: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C19orf44 Gene

Function for C19orf44 Gene

Gene Ontology (GO) - Molecular Function for C19orf44 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with C19orf44: view
genes like me logo Genes that share phenotypes with C19orf44: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C19orf44 Gene

Localization for C19orf44 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C19orf44 gene
Compartment Confidence
nucleus 3
cytosol 3

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C19orf44 Gene

Pathways & Interactions for C19orf44 Gene

SuperPathways for C19orf44 Gene

No Data Available

Interacting Proteins for C19orf44 Gene

Gene Ontology (GO) - Biological Process for C19orf44 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C19orf44 Gene

Transcripts for C19orf44 Gene

Unigene Clusters for C19orf44 Gene

Chromosome 19 open reading frame 44:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C19orf44 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7a · 7b · 7c ^ 8 ^ 9a · 9b ^ 10
SP1:
SP2:
SP3: -
SP4: - -
SP5:

Relevant External Links for C19orf44 Gene

GeneLoc Exon Structure for
C19orf44
ECgene alternative splicing isoforms for
C19orf44

Expression for C19orf44 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for C19orf44 Gene

Protein differential expression in normal tissues from HIPED for C19orf44 Gene

This gene is overexpressed in Heart (39.1) and Lung (29.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C19orf44 Gene



Protein tissue co-expression partners for C19orf44 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of C19orf44 Gene:

C19orf44

SOURCE GeneReport for Unigene cluster for C19orf44 Gene:

Hs.631627

Evidence on tissue expression from TISSUES for C19orf44 Gene

  • Nervous system(2.2)
genes like me logo Genes that share expression patterns with C19orf44: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for C19orf44 Gene

Orthologs for C19orf44 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C19orf44 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C19H19orf44 34
  • 99.31 (n)
C19orf44 35
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia C7H19orf44 34
  • 73.98 (n)
C19orf44 35
  • 59 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C20H19orf44 34
  • 73.77 (n)
C19orf44 35
  • 59 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia RGD1311847 34
  • 66.84 (n)
mouse
(Mus musculus)
Mammalia 1700030K09Rik 34 16 35
  • 66.56 (n)
oppossum
(Monodelphis domestica)
Mammalia C19orf44 35
  • 44 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia C19orf44 35
  • 39 (a)
OneToOne
chicken
(Gallus gallus)
Aves C19orf44 35
  • 29 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia C19orf44 35
  • 32 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii C22H19orf44 35
  • 27 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea -- 35
  • 33 (a)
OneToOne
Species where no ortholog for C19orf44 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C19orf44 Gene

ENSEMBL:
Gene Tree for C19orf44 (if available)
TreeFam:
Gene Tree for C19orf44 (if available)

Paralogs for C19orf44 Gene

No data available for Paralogs for C19orf44 Gene

Variants for C19orf44 Gene

Sequence variations from dbSNP and Humsavar for C19orf44 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs201304731 Uncertain significance 16,495,755(+) CCTTT(A/C)TCTTT upstream-variant-2KB, reference, missense
rs368506422 Uncertain significance 16,496,063(+) TTGGA(A/T)ATAGA upstream-variant-2KB, reference, missense
rs878855223 Uncertain significance 16,496,092(-) ATGCA(C/T)GCTGC upstream-variant-2KB, reference, missense
rs149634686 Benign 16,495,819(+) AGTCA(C/T)TGGTG upstream-variant-2KB, reference, missense
rs1000047279 -- 16,502,452(+) GTGAT(A/G)GTCTC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C19orf44 Gene

Variant ID Type Subtype PubMed ID
esv3370089 CNV insertion 20981092

Variation tolerance for C19orf44 Gene

Residual Variation Intolerance Score: 13.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.06; 21.62% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C19orf44 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
C19orf44

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C19orf44 Gene

Disorders for C19orf44 Gene

Relevant External Links for C19orf44

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C19orf44

No disorders were found for C19orf44 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C19orf44 Gene

Publications for C19orf44 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3 64
  2. A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning. (PMID: 26673895) KA+rlA+ K. … GAPrlich D. (Elife 2015) 3 64
  3. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3 64
  4. Toward a comprehensive characterization of a human cancer cell phosphoproteome. (PMID: 23186163) Zhou H. … Mohammed S. (J. Proteome Res. 2013) 4 64
  5. A directed protein interaction network for investigating intracellular signal transduction. (PMID: 21900206) Vinayagam A. … Wanker E.E. (Sci Signal 2011) 3 64

Products for C19orf44 Gene

Sources for C19orf44 Gene

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